Hypoxia-induced autophagy of stellate cells inhibits expression and secretion of lumican into microenvironment of pancreatic ductal adenocarcinoma

Prolonged exposure to extracellular lumican restrains pancreatic adenocarcinoma growth

(2017) X Li et al.   ONCOGENE

Lumican effectively regulates the estrogen receptors-associated functional properties of breast cancer cells, expression of matrix effectors and epithelial-to-mesenchymal transition

(2017) Konstantina Karamanou et al.   Scientific Reports

Transforming Growth Factor-  Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors

(2016) Y. Kang et al.   CLINICAL CANCER RESEARCH

Ex Vivo Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma

(2016) D. Roife et al.   CLINICAL CANCER RESEARCH

Extracellular lumican augments cytotoxicity of chemotherapy in pancreatic ductal adenocarcinoma cells via autophagy inhibition

(2016) X Li et al.   ONCOGENE

Extracellular Lumican Inhibits Pancreatic Cancer Cell Growth and Is Associated with Prolonged Survival after Surgery

(2014) X. Li et al.   CLINICAL CANCER RESEARCH

Transport properties of pancreatic cancer describe gemcitabine delivery and response

(2014) Eugene J. Koay et al.   JOURNAL OF CLINICAL INVESTIGATION

Lumican effects in the control of tumour progression and their links with metalloproteinases and integrins

(2013) Stéphane Brézillon et al.   FEBS Journal

Lumican affects tumor cell functions, tumor–ECM interactions, angiogenesis and inflammatory response

(2013) Dragana Nikitovic et al.   MATRIX BIOLOGY

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Hypoxia-Induced Aggressiveness of Pancreatic Cancer Cells Is Due to Increased Expression of VEGF, IL-6 and miR-21, Which Can Be Attenuated by CDF Treatment

(2012) Bin Bao et al.   PLoS One

miRNAs in human cancer

(2010) Thalia A Farazi et al.   JOURNAL OF PATHOLOGY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

A complex interplay between Akt, TSC2 and the two mTOR complexes: Figure 1

(2009) Jingxiang Huang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Lumican core protein inhibits melanoma cell migration via alterations of focal adhesion complexes

(2009) Stéphane Brézillon et al.   CANCER LETTERS

Autophagy-A double-edged sword in oncology

(2009) Anja Apel et al.   INTERNATIONAL JOURNAL OF CANCER

Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival

(2009) Thomas Greither et al.   INTERNATIONAL JOURNAL OF CANCER

Looking at Cancer Through an Evolutionary Lens

(2009) Karyn Hede   JNCI-Journal of the National Cancer Institute

A "Lactatic" Perspective on Metabolism

(2009) L. BRUCE GLADDEN   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Generation of orthotopic and heterotopic human pancreatic cancer xenografts in immunodeficient mice

(2009) Michael P Kim et al.   Nature Protocols

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

(2008) R. F. Hwang et al.   CANCER RESEARCH

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

The Activated Stroma Index Is a Novel and Independent Prognostic Marker in Pancreatic Ductal Adenocarcinoma

(2008) Mert Erkan et al.   Clinical Gastroenterology and Hepatology

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY