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Environment-Recognizing DNA-Computation Circuits for the Intracellular Transport of Molecular Payloads for mRNA Imaging

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I-Motif/miniduplex hybrid structures bind benzothiazole dyes with unprecedented efficiencies: a generic light-up system for label-free DNA nanoassemblies and bioimaging

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Monitoring H 2 O 2 on the Surface of Single Cells with Liquid Crystal Elastomer Microspheres

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Programming switchable transcription of topologically constrained DNA

(2020) Kai Jiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Extracellular Ion-Responsive Logic Sensors Utilizing DNA Dimeric Nanoassemblies on Cell Surface and Application to Boosting AS1411 Internalization

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Aptamer-Braked Multi-hairpin Cascade Circuits for Logic-Controlled Label-Free In Situ Bioimaging

(2020) Zhijin Tian et al.   ANALYTICAL CHEMISTRY

Desuccinylation-Triggered Peptide Self-Assembly: Live Cell Imaging of SIRT5 Activity and Mitochondrial Activity Modulation

(2020) Liu Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Beyond Blocking: Engineering RNAi-Mediated Targeted Immune Checkpoint Nanoblocker Enables T-Cell-Independent Cancer Treatment

(2020) Xiaoyan Han et al.   ACS Nano

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Acidification of tumor at stromal boundaries drives transcriptome alterations associated with aggressive phenotypes

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Engineering of Nucleic Acids and Synthetic Cofactors as Holo Sensors for Probing Signaling Molecules in the Cellular Membrane Microenvironment

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Split Dapoxyl Aptamer for Sequence-Selective Analysis of Nucleic Acid Sequence Based Amplification Amplicons

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Intracellular Zinc Quantification by Fluorescence Imaging with a FRET System

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DNA Logic Operations in Living Cells Utilizing Lysosome-Recognizing Framework Nucleic Acid Nanodevices for Subcellular Imaging

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An Acidic-Microenvironment-Driven DNA Nanomachine Enables Specific ATP Imaging in the Extracellular Milieu of Tumor

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Ultrastable Bimolecular G-Quadruplexes Programmed DNA Nanoassemblies for Reconfigurable Biomimetic DNAzymes

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Enhanced Intracellular Ca2+ Nanogenerator for Tumor-Specific Synergistic Therapy via Disruption of Mitochondrial Ca2+ Homeostasis and Photothermal Therapy

(2018) Lihua Xu et al.   ACS Nano

DNA Nanotechnology-Enabled Interfacial Engineering for Biosensor Development

(2018) Dekai Ye et al.   Annual Review of Analytical Chemistry

Framework-Nucleic-Acid-Enabled Biosensor Development

(2018) Fan Yang et al.   ACS Sensors

Integration of Cell-Penetrating Peptides with Rod-like Bionanoparticles: Virus-Inspired Gene-Silencing Technology

(2018) Ye Tian et al.   NANO LETTERS

DNA nanotriangle-scaffolded activatable aptamer probe with ultralow background and robust stability for cancer theranostics

(2018) Yanli Lei et al.   Theranostics

Triggered Reversible Reconfiguration of G-Quadruplex-Bridged “Domino”-Type Origami Dimers: Application of the Systems for Programmed Catalysis

(2018) Jianbang Wang et al.   ACS Nano

Regulation of Ca2+ Signaling for Drug-Resistant Breast Cancer Therapy with Mesoporous Silica Nanocapsule Encapsulated Doxorubicin/siRNA Cocktail

(2018) Shu Wang et al.   ACS Nano

Reconfigurable Bioinspired Framework Nucleic Acid Nanoplatform Dynamically Manipulated in Living Cells for Subcellular Imaging

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Concept and Development of Framework Nucleic Acids

(2018) Zhilei Ge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages

(2018) Toszka Bohn et al.   NATURE IMMUNOLOGY

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(2018) Stéphanie Cornen et al.   SCIENCE

Extracellular nucleosides and nucleotides as immunomodulators

(2017) Oliver Kepp et al.   IMMUNOLOGICAL REVIEWS

A Photoactivatable Probe for Super-Resolution Imaging of Enzymatic Activity in Live Cells

(2017) Elias A. Halabi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Facile Assembly/Disassembly of DNA Nanostructures Anchored on Cell-Mimicking Giant Vesicles

(2017) Ruizi Peng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA probes for monitoring dynamic and transient molecular encounters on live cell membranes

(2017) Mingxu You et al.   Nature Nanotechnology

Programmable i-motif DNA folding topology for a pH-switched reversible molecular sensing device

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Imaging extracellular ATP with a genetically-encoded, ratiometric fluorescent sensor

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An enhanced bioluminescence-based Annexin V probe for apoptosis detection in vitro and in vivo

(2017) Trajen Head et al.   Cell Death & Disease

A Fluorescent Split Aptamer for Visualizing RNA–RNA Assembly In Vivo

(2017) Khalid K. Alam et al.   ACS Synthetic Biology

Thioflavin T behaves as an efficient fluorescent ligand for label-free ATP aptasensor

(2016) Huihui Wang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Ionic immune suppression within the tumour microenvironment limits T cell effector function

(2016) Robert Eil et al.   NATURE

Triplex molecular beacons for sensitive recognition of melamine based on abasic-site-containing DNA and fluorescent silver nanoclusters

(2015) Ya Wang et al.   CHEMICAL COMMUNICATIONS

General Strategy to Introduce pH-Induced Allostery in DNA-Based Receptors to Achieve Controlled Release of Ligands

(2015) Alessandro Porchetta et al.   NANO LETTERS

Chemotherapeutic Drugs Induce ATP Release via Caspase-gated Pannexin-1 Channels and a Caspase/Pannexin-1-independent Mechanism

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Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery

(2014) Wujin Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic Behavior of DNA Cages Anchored on Spherically Supported Lipid Bilayers

(2014) J. W. Conway et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell Membrane-Anchored Biosensors for Real-Time Monitoring of the Cellular Microenvironment

(2014) Liping Qiu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Programmable and Multiparameter DNA-Based Logic Platform For Cancer Recognition and Targeted Therapy

(2014) Mingxu You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Programmable pH-Triggered DNA Nanoswitches

(2014) Andrea Idili et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dual Switchable CRET-Induced Luminescence of CdSe/ZnS Quantum Dots (QDs) by the Hemin/G-Quadruplex-Bridged Aggregation and Deaggregation of Two-Sized QDs

(2014) Lianzhe Hu et al.   NANO LETTERS

Interlocked DNA nanostructures controlled by a reversible logic circuit

(2014) Tao Li et al.   Nature Communications

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Acidity Generated by the Tumor Microenvironment Drives Local Invasion

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I-Motif-Programmed Functionalization of DNA Nanocircles

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DNA Computation in Mammalian Cells: MicroRNA Logic Operations

(2013) James Hemphill et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Input-Dependent Induction of Oligonucleotide Structural Motifs for Performing Molecular Logic

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Cell Surface-Anchored Fluorescent Aptamer Sensor Enables Imaging of Chemical Transmitter Dynamics

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(2011) Weian Zhao et al.   Nature Nanotechnology

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

A Robust Electronic Switch Made of Immobilized Duplex/Quadruplex DNA

(2010) Bixia Ge et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

(2010) Faraaz B. Chekeni et al.   NATURE

DNA Minicircles Connected via G-Quadruplex Interaction Modules

(2010) Diana P. N. Gonçalves et al.   Small

A pH-Triggered, Fast-Responding DNA Hydrogel

(2009) Enjun Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High Specificity, Electrochemical Sandwich Assays Based on Single Aptamer Sequences and Suitable for the Direct Detection of Small-Molecule Targets in Blood and Other Complex Matrices

(2009) Xiaolei Zuo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

Expression, purification and use of recombinant annexin V for the detection of apoptotic cells

(2009) Susan E Logue et al.   Nature Protocols