Chemotherapeutic Drugs Induce ATP Release via Caspase-gated Pannexin-1 Channels and a Caspase/Pannexin-1-independent Mechanism

Intrinsic properties and regulation of Pannexin 1 channel

(2014) Yu-Hsin Chiu et al.   Channels

The role of pannexin1 in the induction and resolution of inflammation

(2014) Samantha E. Adamson et al.   FEBS LETTERS

Unexpected link between an antibiotic, pannexin channels and apoptosis

(2014) Ivan K. H. Poon et al.   NATURE

Pannexin-1 Is Blocked by Its C-Terminus through a Delocalized Non-Specific Interaction Surface

(2014) Michelle Dourado et al.   PLoS One

Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells

(2014) Hiroshi Yamaguchi et al.   eLife

Autophagy-dependent ATP release from dying cells via lysosomal exocytosis

(2013) Yidan Wang et al.   Autophagy

The ubiquitin proteasome system — Implications for cell cycle control and the targeted treatment of cancer

(2013) Florian Bassermann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Molecular mechanisms of ATP secretion during immunogenic cell death

(2013) I Martins et al.   CELL DEATH AND DIFFERENTIATION

The role of the ubiquitin proteasome system in lymphoma

(2013) K. Stephen Suh et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells

(2013) Yuting Ma et al.   IMMUNITY

Structural and Functional Similarities of Calcium Homeostasis Modulator 1 (CALHM1) Ion Channel with Connexins, Pannexins, and Innexins

(2013) Adam P. Siebert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes

(2013) Akiyuki Taruno et al.   NATURE

CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer

(2013) S. Loi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blockade of A2Areceptors potently suppresses the metastasis of CD73+tumors

(2013) Paul A. Beavis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells

(2012) Md. Rafiqul Islam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Function without form: an ongoing search for maxi-anion channel proteins. Focus on “Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells”

(2012) George R. Dubyak   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Premortem autophagy determines the immunogenicity of chemotherapy-induced cancer cell death

(2012) Isabelle Martins et al.   Autophagy

Paracrine signaling through plasma membrane hemichannels

(2012) Nan Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The biochemistry and function of pannexin channels

(2012) Silvia Penuela et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Apaf-1- and Caspase-8-independent apoptosis

(2012) T Imao et al.   CELL DEATH AND DIFFERENTIATION

P2X7 receptor regulation of non-classical secretion from immune effector cells

(2012) George R. Dubyak   CELLULAR MICROBIOLOGY

Pannexin1 Drives Multicellular Aggregate Compaction via a Signaling Cascade That Remodels the Actin Cytoskeleton

(2012) Brian A. Bao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pannexin 1, an ATP Release Channel, Is Activated by Caspase Cleavage of Its Pore-associated C-terminal Autoinhibitory Region

(2012) Joanna K. Sandilos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Pannexin 1 Attenuates Melanoma Progression by Reversion to a Melanocytic Phenotype

(2012) Silvia Penuela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Constitutive lysosome exocytosis releases ATP and engages P2Y receptors in human monocytes

(2012) V. Sivaramakrishnan et al.   JOURNAL OF CELL SCIENCE

The ATP permeability of pannexin 1 channels in a heterologous system and in mammalian taste cells is dispensable

(2012) Roman A. Romanov et al.   JOURNAL OF CELL SCIENCE

Physiological mechanisms for the modulation of pannexin 1 channel activity

(2012) Joanna K. Sandilos et al.   JOURNAL OF PHYSIOLOGY-LONDON

Inflammasomes in carcinogenesis and anticancer immune responses

(2012) Laurence Zitvogel et al.   NATURE IMMUNOLOGY

Pannexin 1 forms an anion-selective channel

(2012) Weihong Ma et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability

(2012) Z. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vesicular and conductive mechanisms of nucleotide release

(2012) Eduardo R. Lazarowski   Purinergic Signalling

CD73: a potent suppressor of antitumor immune responses

(2012) Paul. A. Beavis et al.   TRENDS IN IMMUNOLOGY

Proteasome inhibitor MG132-induced apoptosis via ER stress-mediated apoptotic pathway and its potentiation by protein tyrosine kinase p56lck in human Jurkat T cells

(2011) Hae Sun Park et al.   BIOCHEMICAL PHARMACOLOGY

CD73-Deficient Mice Have Increased Antitumor Immunity and Are Resistant to Experimental Metastasis

(2011) J. Stagg et al.   CANCER RESEARCH

Altered purinergic signaling in CD73-deficient mice inhibits tumor progression

(2011) Gennady G. Yegutkin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1

(2011) Joachim Manns et al.   FASEB JOURNAL

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

(2011) Balázs Csóka et al.   FASEB JOURNAL

Pathways Regulating the Trafficking and Turnover of Pannexin1 Protein and the Role of the C-terminal Domain

(2011) Ruchi Gehi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of Adenosine A2A Receptors in Engulfment-Dependent Apoptotic Cell Suppression of Inflammation

(2011) K. Koroskenyi et al.   JOURNAL OF IMMUNOLOGY

Pannexin-1 Is Required for ATP Release during Apoptosis but Not for Inflammasome Activation

(2011) Y. Qu et al.   JOURNAL OF IMMUNOLOGY

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse

(2010) T. Woehrle et al.   BLOOD

Chemotherapy induces ATP release from tumor cells

(2010) Isabelle Martins et al.   CELL CYCLE

Involvement of SLC17A9-dependent Vesicular Exocytosis in the Mechanism of ATP Release during T Cell Activation

(2010) Akihiro Tokunaga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pannexin1 and Pannexin3 Delivery, Cell Surface Dynamics, and Cytoskeletal Interactions

(2010) Ruchi Bhalla-Gehi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pannexin1 and Pannexin2 Channels Show Quaternary Similarities to Connexons and Different Oligomerization Numbers from Each Other

(2010) Cinzia Ambrosi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Implications of pannexin 1 and pannexin 3 for keratinocyte differentiation

(2010) S. J. Celetti et al.   JOURNAL OF CELL SCIENCE

SCAM analysis of Panx1 suggests a peculiar pore structure

(2010) Junjie Wang et al.   JOURNAL OF GENERAL PHYSIOLOGY

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

(2010) Faraaz B. Chekeni et al.   NATURE

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

(2010) J. Stagg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autocrine regulation of T-cell activation by ATP release and P2X7 receptors

(2009) Linda Yip et al.   FASEB JOURNAL

Glycosylation Regulates Pannexin Intermixing and Cellular Localization

(2009) Silvia Penuela et al.   MOLECULAR BIOLOGY OF THE CELL

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

P2X7 receptors regulate multiple types of membrane trafficking responses and non-classical secretion pathways

(2009) Yan Qu et al.   Purinergic Signalling

A2B adenosine receptors in immunity and inflammation

(2009) György Haskó et al.   TRENDS IN IMMUNOLOGY

A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP

(2008) Feng Qiu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk

(2008) Ute Dreses-Werringloer et al.   CELL

Trafficking Dynamics of Glycosylated Pannexin1 Proteins

(2008) Daniela Boassa et al.   CELL COMMUNICATION AND ADHESION

The immunogenicity of tumor cell death

(2008) Oliver Kepp et al.   CURRENT OPINION IN ONCOLOGY

Antigen-independent adhesion and cell spreading by inducible costimulator engagement inhibits T cell migration in a PI-3K-dependent manner

(2008) Jennifer L. Franko et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Linking Calcium to Aβ and Alzheimer's Disease

(2008) Kim N. Green et al.   NEURON

Identification of a vesicular nucleotide transporter

(2008) K. Sawada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA