Potential roles of gut microbiota and microbial metabolites in Parkinson’s disease

Pathomechanism Characterization and Potential Therapeutics Identification for Parkinson’s Disease Targeting Neuroinflammation

(2021) Chiung-Mei Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A narrative review of relationship between gut microbiota and neuropsychiatric disorders: mechanisms and clinical application of probiotics and prebiotics

(2021) Huan Yang et al.   Annals of Palliative Medicine

Hydrogen sulfide in longevity and pathologies: Inconsistency is malodorous

(2021) Alexander S. Sokolov et al.   AGEING RESEARCH REVIEWS

Regulation of immune-driven pathogenesis in Parkinson’s disease by gut microbiota

(2020) Wenxia Zheng et al.   BRAIN BEHAVIOR AND IMMUNITY

Diagnosis and Treatment of Parkinson Disease

(2020) Melissa J. Armstrong et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Progressive Supranuclear Palsy Clinical Deficits Scale

(2020) Ines Piot et al.   MOVEMENT DISORDERS

Regulation of intestinal lipid metabolism: current concepts and relevance to disease

(2020) Chih-Wei Ko et al.   Nature Reviews Gastroenterology & Hepatology

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

(2020) Aonghus Lavelle et al.   Nature Reviews Gastroenterology & Hepatology

Treatment of Nonmotor Symptoms Associated with Parkinson Disease

(2020) Jennifer G. Goldman et al.   NEUROLOGIC CLINICS

Therapies to modulate gut microbiota: Past, present and future

(2020) Akshita Gupta et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Gut Microbiota Altered in Mild Cognitive Impairment Compared With Normal Cognition in Sporadic Parkinson's Disease

(2020) Tengzhu Ren et al.   Frontiers in Neurology

Synucleinphagy: a microglial “community cleanup program” for neuroprotection

(2020) Insup Choi et al.   Autophagy

Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction

(2020) Zhenwei Yu et al.   BRAIN

Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism

(2020) Alexander Duscha et al.   CELL

Plasma Short‐Chain Fatty Acids in Patients With Parkinson's Disease

(2020) Chaewon Shin et al.   MOVEMENT DISORDERS

Host–microbiota interactions in immune-mediated diseases

(2020) William E. Ruff et al.   NATURE REVIEWS MICROBIOLOGY

Clinical implications of gastric complications on levodopa treatment in Parkinson's disease

(2020) Ronald F. Pfeiffer et al.   PARKINSONISM & RELATED DISORDERS

Role of Alterations in Protein Kinase p38γ in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and α-Synuclein Transgenic Models

(2020) Michiyo Iba et al.   Frontiers in Neuroscience

Gut Microbiome-Modified Polyphenolic Compounds Inhibit α-Synuclein Seeding and Spreading in α-Synucleinopathies

(2020) Tritia R. Yamasaki et al.   Frontiers in Neuroscience

Gut microbiota from persons with attention-deficit/hyperactivity disorder affects the brain in mice

(2020) Anouk C. Tengeler et al.   Microbiome

Probiotics Alleviate the Progressive Deterioration of Motor Functions in a Mouse Model of Parkinson's Disease

(2020) Tsung-Hsun Hsieh et al.   Brain Sciences

The Gut Microbiota and Unhealthy Aging: Disentangling Cause from Consequence

(2020) Erica N. DeJong et al.   Cell Host & Microbe

Identification and optimization of piperine analogues as neuroprotective agents for the treatment of Parkinson’s disease via the activation of Nrf2/keap1 pathway

(2020) Lun Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Intrepidly studying deep brain stimulation in patients with Parkinson's disease

(2020) Günther Deuschl et al.   LANCET NEUROLOGY

Hydrogen sulfide alleviates oxidative stress injury and reduces apoptosis induced by MPP+ in Parkinson’s disease cell model

(2020) Lin Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Virtual reality in research and rehabilitation of gait and balance in Parkinson disease

(2020) Colleen G. Canning et al.   Nature Reviews Neurology

Sodium Butyrate Exacerbates Parkinson’s Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model

(2020) Chen-Meng Qiao et al.   NEUROCHEMICAL RESEARCH

Deep brain stimulation in early-stage Parkinson disease

(2020) Mallory L. Hacker et al.   NEUROLOGY

Gut metagenomics-derived genes as potential biomarkers of Parkinson’s disease

(2020) Yiwei Qian et al.   BRAIN

Probiotic Clostridium Butyricum Ameliorated Motor Deficits in a Mouse Model of Parkinson's Disease via Gut Microbiota-GLP-1 Pathway

(2020) Jing Sun et al.   BRAIN BEHAVIOR AND IMMUNITY

Fecal microbiota transplantation therapy for Parkinson's disease

(2020) Liu-Jun Xue et al.   MEDICINE

Helicobacter pylori Eradication in Parkinson's Disease: A Randomized Placebo‐Controlled Trial

(2020) Ai Huey Tan et al.   MOVEMENT DISORDERS

Probiotics for constipation in Parkinson’s disease: A randomized placebo-controlled study

(2020) Ai Huey Tan et al.   NEUROLOGY

Clostridium butyricum protects intestinal barrier function via upregulation of tight junction proteins and activation of the Akt/mTOR signaling pathway in a mouse model of dextran sodium sulfate‑induced colitis

(2020) Miao Liu et al.   Experimental and Therapeutic Medicine

Neuroprotective Effects of Molecular Hydrogen: A Critical Review

(2020) Wei Chen et al.   Neuroscience Bulletin

Gut Microbial Ecosystem in Parkinson Disease: New Clinicobiological Insights from Multi‐Omics

(2020) Ai Huey Tan et al.   ANNALS OF NEUROLOGY

Acylated Ghrelin as a Multi-Targeted Therapy for Alzheimer's and Parkinson's Disease

(2020) Niklas Reich et al.   Frontiers in Neuroscience

The Gut Mycobiome in Parkinson’s Disease

(2020) Mihai S. Cirstea et al.   Journal of Parkinsons Disease

Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease

(2019) Sebastiaan P. van Kessel et al.   Nature Communications

Lactobacillus plantarum DR7 alleviates stress and anxiety in adults: a randomised, double-blind, placebo-controlled study

(2019) H.X. Chong et al.   Beneficial Microbes

Psychotropics and the Microbiome: a Chamber of Secrets…

(2019) Sofia Cussotto et al.   PSYCHOPHARMACOLOGY

Fecal microbiota transplantation for treatment of recurrent C. difficile infection: An updated randomized controlled trial meta-analysis

(2019) Wenjia Hui et al.   PLoS One

Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson’s Disease Mice via Gut Microbiota and Metabolites

(2019) Zhi-Lan Zhou et al.   Neurotherapeutics

Sensitivity and Specificity of Diagnostic Criteria for Progressive Supranuclear Palsy

(2019) Farwa Ali et al.   MOVEMENT DISORDERS

Toward the discovery and development of effective modulators of α-synuclein amyloid aggregation

(2019) Valentina Oliveri   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The role of short-chain fatty acids in microbiota–gut–brain communication

(2019) Boushra Dalile et al.   Nature Reviews Gastroenterology & Hepatology

Fecal microbiota transplant for Crohn disease: A study evaluating safety, efficacy, and microbiome profile

(2019) Liat Gutin et al.   United European Gastroenterology Journal

Toll-like receptors and their therapeutic potential in Parkinson’s disease and α-synucleinopathies

(2019) Antonina Kouli et al.   BRAIN BEHAVIOR AND IMMUNITY

Role of Vitamin D in Multiple Sclerosis and Other Neurodegenerative Processes: Bibliometric Analysis and Systematic Review

(2019) Javier Caballero-Villarraso et al.   CNS & Neurological Disorders-Drug Targets

Gut microbiota, dysbiosis and colon lavage

(2019) Lorenzo Drago et al.   DIGESTIVE AND LIVER DISEASE

Altered gut microbiota and inflammatory cytokine responses in patients with Parkinson’s disease

(2019) Chin-Hsien Lin et al.   Journal of Neuroinflammation

Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity

(2019) Sunil Srivastav et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Parkinsonism in essential tremor cases: A clinicopathological study

(2019) Ali H. Rajput et al.   MOVEMENT DISORDERS

Dysbiosis of gut microbiota in a selected population of Parkinson's patients

(2019) Daniele Pietrucci et al.   PARKINSONISM & RELATED DISORDERS

Oral administration of heat-killed Lactobacillus brevis SBC8803 elevates the ratio of acyl/des-acyl ghrelin in blood and increases short-term food intake

(2019) H. Saito et al.   Beneficial Microbes

Parkinson’s Disease: The Emerging Role of Gut Dysbiosis, Antibiotics, Probiotics, and Fecal Microbiota Transplantation

(2019) Sudhir K Dutta et al.   Journal of Neurogastroenterology and Motility

Gut microbiota in Parkinson's disease: Temporal stability and relations to disease progression

(2019) Velma T.E. Aho et al.   EBioMedicine

Gastrointestinal Care of the Parkinson Patient

(2019) John Legge et al.   CLINICS IN GERIATRIC MEDICINE

Probiotics for Parkinson’s Disease

(2019) Gazerani   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alteration of the fecal microbiota in North-Eastern Han Chinese population with sporadic Parkinson’s disease

(2019) Fang Li et al.   NEUROSCIENCE LETTERS

The Microbiota-Gut-Brain Axis

(2019) John F. Cryan et al.   PHYSIOLOGICAL REVIEWS

Increasing Comparability and Utility of Gut Microbiome Studies in Parkinson’s Disease: A Systematic Review

(2019) Jeffrey M. Boertien et al.   Journal of Parkinsons Disease

Lactulose: Patient- and dose-dependent prebiotic properties in humans

(2019) Jakub Ruszkowski et al.   ANAEROBE

Parkinson disease

(2019) R. Balestrino et al.   EUROPEAN JOURNAL OF NEUROLOGY

Selegiline: a molecule with innovative potential

(2019) Tamás Tábi et al.   JOURNAL OF NEURAL TRANSMISSION

The gut microbiome in neurological disorders

(2019) John F Cryan et al.   LANCET NEUROLOGY

Altered gut microbiota and intestinal permeability in Parkinson’s disease: Pathological highlight to management

(2019) Shakshi Sharma et al.   NEUROSCIENCE LETTERS

Bacterial Metabolites Mirror Altered Gut Microbiota Composition in Patients with Parkinson’s Disease

(2019) Sebastiaan P. van Kessel et al.   Journal of Parkinsons Disease

Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway

(2019) Chen-Meng Qiao et al.   EXPERIMENTAL CELL RESEARCH

Dysbiosis of gut microbiota and microbial metabolites in Parkinson’s Disease

(2018) Meng-Fei Sun et al.   AGEING RESEARCH REVIEWS

Neuroprotective effects of fecal microbiota transplantation on MPTP-induced Parkinson’s disease mice: Gut microbiota, glial reaction and TLR4/TNF-α signaling pathway

(2018) Meng-Fei Sun et al.   BRAIN BEHAVIOR AND IMMUNITY

Alteration of the fecal microbiota in Chinese patients with Parkinson’s disease

(2018) Yiwei Qian et al.   BRAIN BEHAVIOR AND IMMUNITY

In vitro fermentation of Cookeina speciosa glucans stimulates the growth of the butyrogenic Clostridium cluster XIVa in a targeted way

(2018) Thaisa Moro Cantu-Jungles et al.   CARBOHYDRATE POLYMERS

Clinical and metabolic response to probiotic administration in people with Parkinson's disease: A randomized, double-blind, placebo-controlled trial

(2018) Omid Reza Tamtaji et al.   CLINICAL NUTRITION

Faecal microbiota transplantation alters gut microbiota in patients with irritable bowel syndrome: results from a randomised, double-blind placebo-controlled study

(2018) Sofie Ingdam Halkjær et al.   GUT

Network imaging biomarkers: insights and clinical applications in Parkinson's disease

(2018) Katharina A Schindlbeck et al.   LANCET NEUROLOGY

Current understanding of the human microbiome

(2018) Jack A Gilbert et al.   NATURE MEDICINE

Inadequate Production of H 2 by Gut Microbiota and Parkinson Disease

(2018) Sergej M. Ostojic   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Oral administration of Proteus mirabilis damages dopaminergic neurons and motor functions in mice

(2018) Jin Gyu Choi et al.   Scientific Reports

Efficacy of different faecal microbiota transplantation protocols for Clostridium difficile infection: A systematic review and meta-analysis

(2018) Gianluca Ianiro et al.   United European Gastroenterology Journal

Sodium Butyrate Inhibits Inflammation and Maintains Epithelium Barrier Integrity in a TNBS-induced Inflammatory Bowel Disease Mice Model

(2018) Guangxin Chen et al.   EBioMedicine

Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain-gut axis alterations

(2018) Marcel van de Wouw et al.   JOURNAL OF PHYSIOLOGY-LONDON

Fecal microbiota transplantation: Review and update

(2018) Jiunn-Wei Wang et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Extensive impact of non-antibiotic drugs on human gut bacteria

(2018) Lisa Maier et al.   NATURE

Intestinal Pathology and Gut Microbiota Alterations in a Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Mouse Model of Parkinson’s Disease

(2018) Feng Lai et al.   NEUROCHEMICAL RESEARCH

Gut microbiota in patients with Parkinson's disease in southern China

(2018) Aiqun Lin et al.   PARKINSONISM & RELATED DISORDERS

Parkinson’s disease and bacteriophages as its overlooked contributors

(2018) George Tetz et al.   Scientific Reports

The Human Gut Microbiome – A Potential Controller of Wellness and Disease

(2018) Zhi Y. Kho et al.   Frontiers in Microbiology

Role of TLR4 in the gut-brain axis in Parkinson’s disease: a translational study from men to mice

(2018) Paula Perez-Pardo et al.   GUT

Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) E. Ray Dorsey et al.   LANCET NEUROLOGY

Parkinson Disease

(2018) Stephen G. Reich et al.   MEDICAL CLINICS OF NORTH AMERICA

Unraveling gut microbiota in Parkinson's disease and atypical parkinsonism

(2018) Michela Barichella et al.   MOVEMENT DISORDERS

Microbial treatment: the potential application for Parkinson’s disease

(2018) Xin Fang   NEUROLOGICAL SCIENCES

Oxidative Stress and the Microbiota-Gut-Brain Axis

(2018) Laura Dumitrescu et al.   Oxidative Medicine and Cellular Longevity

Quantification of hydrogen production by intestinal bacteria that are specifically dysregulated in Parkinson's disease

(2018) Anzu Suzuki et al.   PLoS One

Probiotics and Prebiotics as a Therapeutic Strategy to Improve Memory in a Model of Middle-Aged Rats

(2018) Alejandra Romo-Araiza et al.   Frontiers in Aging Neuroscience

The Emerging Evidence of the Parkinson Pandemic

(2018) E. Ray Dorsey et al.   Journal of Parkinsons Disease

The gut-brain axis in Parkinson's disease: Possibilities for food-based therapies

(2017) Paula Perez-Pardo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage

(2017) Isabel Paiva et al.   HUMAN MOLECULAR GENETICS

Homologous HSV1 and alpha-synuclein peptides stimulate a T cell response in Parkinson's disease

(2017) E. Caggiu et al.   JOURNAL OF NEUROIMMUNOLOGY

Sodium butyrate exerts protective effect against Parkinson's disease in mice via stimulation of glucagon like peptide-1

(2017) Jiaming Liu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2017) Valery L Feigin et al.   LANCET NEUROLOGY

The SH-SY5Y cell line in Parkinson’s disease research: a systematic review

(2017) Helena Xicoy et al.   Molecular Neurodegeneration

Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome

(2017) Erin M. Hill-Burns et al.   MOVEMENT DISORDERS

The nasal and gut microbiome in Parkinson's disease and idiopathic rapid eye movement sleep behavior disorder

(2017) Anna Heintz-Buschart et al.   MOVEMENT DISORDERS

Brain–gut–microbiota axis — mood, metabolism and behaviour

(2017) Timothy G. Dinan et al.   Nature Reviews Gastroenterology & Hepatology

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

(2017) Glenn R. Gibson et al.   Nature Reviews Gastroenterology & Hepatology

Hydrogen sulfide in stroke: Protective or deleterious?

(2017) Su Jing Chan et al.   NEUROCHEMISTRY INTERNATIONAL

Vagotomy and Parkinson disease

(2017) Bojing Liu et al.   NEUROLOGY

Oral and nasal microbiota in Parkinson's disease

(2017) Pedro A.B. Pereira et al.   PARKINSONISM & RELATED DISORDERS

Progression of Parkinson's disease is associated with gut dysbiosis: Two-year follow-up study

(2017) Tomomi Minato et al.   PLoS One

Involvement of the kynurenine pathway in the pathogenesis of Parkinson’s disease

(2017) Chai K. Lim et al.   PROGRESS IN NEUROBIOLOGY

Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation

(2017) Koji Atarashi et al.   SCIENCE

Structural changes of gut microbiota in Parkinson’s disease and its correlation with clinical features

(2017) Wei Li et al.   Science China-Life Sciences

Feeding the microbiota-gut-brain axis: diet, microbiome, and neuropsychiatry

(2017) Kiran V. Sandhu et al.   Translational Research

Brain Autoimmunity and Intestinal Microbiota: 100 Trillion Game Changers

(2017) Hartmut Wekerle   TRENDS IN IMMUNOLOGY

Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson’s disease patients

(2017) J. R. Bedarf et al.   Genome Medicine

Prion-Like Domains in Phagobiota

(2017) George Tetz et al.   Frontiers in Microbiology

Exploring Braak’s Hypothesis of Parkinson’s Disease

(2017) Carmen D. Rietdijk et al.   Frontiers in Neurology

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

(2017) Dae-Wook Kang et al.   Microbiome

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

Identification of donor microbe species that colonize and persist long term in the recipient after fecal transplant for recurrent Clostridium difficile

(2017) Ranjit Kumar et al.   npj Biofilms and Microbiomes

Brain-to-stomach transfer of α-synuclein via vagal preganglionic projections

(2016) Ayse Ulusoy et al.   ACTA NEUROPATHOLOGICA

Pathological α-synuclein in gastrointestinal tissues from prodromal Parkinson disease patients

(2016) Morten Gersel Stokholm et al.   ANNALS OF NEUROLOGY

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Short- and medium-chain fatty acids in energy metabolism: the cellular perspective

(2016) Peter Schönfeld et al.   JOURNAL OF LIPID RESEARCH

Humoral cross reactivity between α-synuclein and herpes simplex-1 epitope in Parkinson's disease, a triggering role in the disease?

(2016) Elisa Caggiu et al.   JOURNAL OF NEUROIMMUNOLOGY

Probiotics and prebiotic fiber for constipation associated with Parkinson disease

(2016) Michela Barichella et al.   NEUROLOGY

Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls

(2016) Marcus M. Unger et al.   PARKINSONISM & RELATED DISORDERS

Bacteriophage infections of microbiota can lead to leaky gut in an experimental rodent model

(2016) George Tetz et al.   Gut Pathogens

Effect of Probiotics on Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2016) Ruixue Huang et al.   Nutrients

Intestinal Microbiota Distinguish Gout Patients from Healthy Humans

(2016) Zhuang Guo et al.   Scientific Reports

Nonmotor gastrointestinal disorders in older patients with Parkinson’s disease: is there hope?

(2016) Doina Georgescu et al.   Clinical Interventions in Aging

Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant

(2016) Claire Hoenen et al.   PLoS One

Vagotomy and subsequent risk of Parkinson's disease

(2015) Elisabeth Svensson et al.   ANNALS OF NEUROLOGY

Beneficial effects of sodium butyrate in 6-OHDA induced neurotoxicity and behavioral abnormalities: Modulation of histone deacetylase activity

(2015) Sorabh Sharma et al.   BEHAVIOURAL BRAIN RESEARCH

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

Control of Brain Development, Function, and Behavior by the Microbiome

(2015) Timothy R. Sampson et al.   Cell Host & Microbe

Risk and Safety of Probiotics

(2015) Shira Doron et al.   CLINICAL INFECTIOUS DISEASES

How informative is the mouse for human gut microbiota research?

(2015) T. L. A. Nguyen et al.   Disease Models & Mechanisms

Modulation of Gut Microbiota–Brain Axis by Probiotics, Prebiotics, and Diet

(2015) Xiaofei Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Suppression of MAPK attenuates neuronal cell death induced by activated glia-conditioned medium in alpha-synuclein overexpressing SH-SY5Y cells

(2015) Lidia M. Yshii et al.   Journal of Neuroinflammation

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Colonic bacterial composition in Parkinson's disease

(2015) Ali Keshavarzian et al.   MOVEMENT DISORDERS

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Towards microbial fermentation metabolites as markers for health benefits of prebiotics

(2015) Kristin A. Verbeke et al.   NUTRITION RESEARCH REVIEWS

Fecal microbiota transplantation broadening its application beyond intestinal disorders

(2015) Meng-Que Xu   WORLD JOURNAL OF GASTROENTEROLOGY

Brain-gut-microbiota axis in Parkinson's disease

(2015) Agata Mulak   WORLD JOURNAL OF GASTROENTEROLOGY

Reduction of butyrate- and methane-producing microorganisms in patients with Irritable Bowel Syndrome

(2015) Marta Pozuelo et al.   Scientific Reports

Probiotic-based strategies for therapeutic and prophylactic use against multiple gastrointestinal diseases

(2015) Natallia V. Varankovich et al.   Frontiers in Microbiology

Meta-analyses on prevalence of selected Parkinson’s nonmotor symptoms before and after diagnosis

(2015) Honglei Chen et al.   Translational Neurodegeneration

Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury

(2015) Ayse Ulusoy et al.   Acta Neuropathologica Communications

Structural alterations of the intestinal epithelial barrier in Parkinson’s disease

(2015) Thomas Clairembault et al.   Acta Neuropathologica Communications

Intestinal Dysbiosis and Lowered Serum Lipopolysaccharide-Binding Protein in Parkinson’s Disease

(2015) Satoru Hasegawa et al.   PLoS One

Hydrogen Sulfide: A Neuromodulator and Neuroprotectant in the Central Nervous System

(2014) Xingzhou Zhang et al.   ACS Chemical Neuroscience

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

(2014) Staffan Holmqvist et al.   ACTA NEUROPATHOLOGICA

Effect of Probiotic Lactobacillus salivarius UBL S22 and Prebiotic Fructo-oligosaccharide on Serum Lipids, Inflammatory Markers, Insulin Sensitivity, and Gut Bacteria in Healthy Young Volunteers

(2014) Hemalatha Rajkumar et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Rapid and Sustained Long-Term Decrease of Fecal Short-Chain Fatty Acids in Critically Ill Patients With Systemic Inflammatory Response Syndrome

(2014) Tomoki Yamada et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Gut microbiota are related to Parkinson's disease and clinical phenotype

(2014) Filip Scheperjans et al.   MOVEMENT DISORDERS

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

(2014) Colin Hill et al.   Nature Reviews Gastroenterology & Hepatology

Effects of Fructo-Oligosaccharide Supplementation on Constipation in Elderly Continuous Ambulatory Peritoneal Dialysis Patients

(2014) K. Meksawan et al.   PERITONEAL DIALYSIS INTERNATIONAL

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Exploiting gut bacteriophages for human health

(2014) Marion Dalmasso et al.   TRENDS IN MICROBIOLOGY

Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes

(2014) Chi Liu et al.   Scientific Reports

Mechanisms underlying immune effects of dietary oligosaccharides

(2013) Prescilla V Jeurink et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease

(2013) Leo P. Kelly et al.   MOVEMENT DISORDERS

Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-d-aspartate receptor subunits and d-serine

(2013) Helene M. Savignac et al.   NEUROCHEMISTRY INTERNATIONAL

Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson’s disease

(2013) R. St. Laurent et al.   NEUROSCIENCE

Epigenetic targeting of histone deacetylase: Therapeutic potential in Parkinson's disease?

(2013) Ian F. Harrison et al.   PHARMACOLOGY & THERAPEUTICS

Oral ‘hydrogen water’ induces neuroprotective ghrelin secretion in mice

(2013) Akio Matsumoto et al.   Scientific Reports

Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice

(2012) Yasunari Asano et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The interplay between the intestinal microbiota and the brain

(2012) Stephen M. Collins et al.   NATURE REVIEWS MICROBIOLOGY

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

Phenylbutyrate Up-regulates the DJ-1 Protein and Protects Neurons in Cell Culture and in Animal Models of Parkinson Disease

(2011) Wenbo Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Probiotics, prebiotics, and synbiotics: impact on the gut immune system and allergic reactions

(2011) P. Gourbeyre et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication

(2011) P. Bercik et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease

(2011) Christopher B. Forsyth et al.   PLoS One

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenome targeting by probiotic metabolites

(2011) Paul V Licciardi et al.   Gut Pathogens

Inhaled Hydrogen Sulfide Prevents Neurodegeneration and Movement Disorder in a Mouse Model of Parkinson's Disease

(2010) Kotaro Kida et al.   ANTIOXIDANTS & REDOX SIGNALING

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys

(2010) Daniella Rylander et al.   NEUROBIOLOGY OF DISEASE

Use of pre-, pro- and synbiotics in patients with acute pancreatitis: A meta-analysis

(2010) Ming-Ming Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

Neuroprotective effects of hydrogen sulfide on Parkinson’s disease rat models

(2009) Li-Fang Hu et al.   AGING CELL

GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

(2009) M. Thangaraju et al.   CANCER RESEARCH

Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling

(2009) John W. Calvert et al.   CIRCULATION RESEARCH

Alpha-synuclein immunopositive aggregates in the myenteric plexus of the aging Fischer 344 rat

(2009) Robert J. Phillips et al.   EXPERIMENTAL NEUROLOGY

The blood–brain barrier and immune function and dysfunction

(2009) William A. Banks et al.   NEUROBIOLOGY OF DISEASE

Medical records documentation of constipation preceding Parkinson disease: A case-control study

(2009) R. Savica et al.   NEUROLOGY

Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease

(2009) Kyota Fujita et al.   PLoS One

Probiotics: Role in Pathophysiology and Prevention in Necrotizing Enterocolitis

(2008) Camilia R. Martin et al.   SEMINARS IN PERINATOLOGY