Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage

Gene Expression Differences in Peripheral Blood of Parkinson’s Disease Patients with Distinct Progression Profiles

(2016) Raquel Pinho et al.   PLoS One

Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease

(2016) Sara Sepe et al.   Cell Reports

BRCA1 and p53 Tumor Suppressor Molecules in Alzheimer’s Disease

(2015) Atsuko Nakanishi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structure, function and toxicity of alpha-synuclein: the Bermuda triangle in synucleinopathies

(2015) Anna Villar-Piqué et al.   JOURNAL OF NEUROCHEMISTRY

The associations between Parkinson’s disease and cancer: the plot thickens

(2015) Danielle D. Feng et al.   Translational Neurodegeneration

Mitochondrial Dysfunction in Parkinson's Disease

(2015) Hyo Eun Moon et al.   Experimental Neurobiology

Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization

(2014) Judith Eschbach et al.   ANNALS OF NEUROLOGY

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

(2014) Katrina J. Falkenberg et al.   NATURE REVIEWS DRUG DISCOVERY

DNA Damage and Its Links to Neurodegeneration

(2014) Ram Madabhushi et al.   NEURON

α-Synuclein Overexpression Represses 14-3-3θ Transcription

(2013) Huiping Ding et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Transcriptional regulation and its misregulation in Alzheimer’s disease

(2013) Xiao-Fen Chen et al.   Molecular Brain

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

(2012) Jian Ye et al.   BMC BIOINFORMATICS

Anti-Parkinsonian Effects of Nurr1 Activator in Ubiquitin-Proteasome System Impairment Induced Animal Model of Parkinson’s Disease

(2012) Zhen Zhang et al.   CNS & Neurological Disorders-Drug Targets

Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: Implications for Parkinson’s disease

(2012) Almas Siddiqui et al.   FREE RADICAL BIOLOGY AND MEDICINE

α-Synuclein Induces Alterations in Adult Neurogenesis in Parkinson Disease Models via p53-mediated Repression of Notch1

(2012) Paula Desplats et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons

(2012) M. Decressac et al.   Science Translational Medicine

Interference of alpha-synuclein with cAMP/PKA-dependent CREB signaling for tyrosine hydroxylase gene expression in SK-N-BE(2)C cells

(2011) Sa Suk Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Biophysics of α-synuclein membrane interactions

(2011) Candace M. Pfefferkorn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Alpha-synuclein functions in the nucleus to protect against hydroxyurea-induced replication stress in yeast

(2011) Xianpeng Liu et al.   HUMAN MOLECULAR GENETICS

Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line

(2011) Diana Scholz et al.   JOURNAL OF NEUROCHEMISTRY

 -Synuclein Negatively Regulates Protein Kinase C  Expression to Suppress Apoptosis in Dopaminergic Neurons by Reducing p300 Histone Acetyltransferase Activity

(2011) H. Jin et al.   JOURNAL OF NEUROSCIENCE

Meta-analysis of genetic and environmental Parkinson's disease models reveals a common role of mitochondrial protection pathways

(2011) Lilach Soreq et al.   NEUROBIOLOGY OF DISEASE

Parkinson's Disease Therapeutics: New Developments and Challenges Since the Introduction of Levodopa

(2011) Yoland Smith et al.   NEUROPSYCHOPHARMACOLOGY

The regulatory role of α-synuclein and parkin in neuronal cell apoptosis; possible implications for the pathogenesis of Parkinson’s disease

(2010) Toru Yasuda et al.   APOPTOSIS

Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo

(2010) Shankar J. Chinta et al.   NEUROSCIENCE LETTERS

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics

Valproic Acid is Neuroprotective in the Rotenone Rat Model of Parkinson’s Disease: Involvement of α-Synuclein

(2009) Barbara Monti et al.   NEUROTOXICITY RESEARCH

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial association of alpha-synuclein causes oxidative stress

(2008) M. S. Parihar et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain

(2008) Latha Devi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional dysregulation in a transgenic model of Parkinson disease

(2007) Talene A. Yacoubian et al.   NEUROBIOLOGY OF DISEASE