The Human Gut Microbiome – A Potential Controller of Wellness and Disease

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis in Mice via a Toll-Like Receptor 4/p21-Activated Kinase 1 Cascade

(2018) Yaxin Wu et al.   DIGESTIVE DISEASES AND SCIENCES

Effect of methotrexate/vitamin B12 on DNA methylation as a potential factor in leukemia treatment-related neurotoxicity

(2017) Victoria J Forster et al.   Epigenomics

Dietary fibre-based SCFA mixtures promote both protection and repair of intestinal epithelial barrier function in a Caco-2 cell model

(2017) Tingting Chen et al.   Food & Function

Modulatory Influence of Segmented Filamentous Bacteria on Transcriptomic Response of Gnotobiotic Mice Exposed to TCDD

(2017) Robert D. Stedtfeld et al.   Frontiers in Microbiology

Transglutaminases in Dysbiosis As Potential Environmental Drivers of Autoimmunity

(2017) Aaron Lerner et al.   Frontiers in Microbiology

Pro- and anti-inflammatory responses of peripheral blood mononuclear cells induced by Staphylococcus aureus and Pseudomonas aeruginosa phages

(2017) Jonas D. Van Belleghem et al.   Scientific Reports

Fap2 Mediates Fusobacterium nucleatum Colorectal Adenocarcinoma Enrichment by Binding to Tumor-Expressed Gal-GalNAc

(2016) Jawad Abed et al.   Cell Host & Microbe

Oxidative Stress and Nitric Oxide in Autism Spectrum Disorder and Other Neuropsychiatric Disorders

(2016) Kunio Yui et al.   CNS & Neurological Disorders-Drug Targets

Gut Microbiota and Celiac Disease

(2016) Giovanni Marasco et al.   DIGESTIVE DISEASES AND SCIENCES

Global patterns and trends in colorectal cancer incidence and mortality

(2016) Melina Arnold et al.   GUT

Enteric Glial Cells

(2016) Fernando Ochoa-Cortes et al.   INFLAMMATORY BOWEL DISEASES

Interaction between gut microbiota and toll-like receptor: from immunity to metabolism

(2016) Jensen H.C. Yiu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

(2016) John R. Kelly et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Butyrate production from high-fiber diet protects against lymphoma tumor

(2016) Wei Wei et al.   LEUKEMIA & LYMPHOMA

Vitamin D deficiency changes the intestinal microbiome reducing B vitamin production in the gut. The resulting lack of pantothenic acid adversely affects the immune system, producing a “pro-inflammatory” state associated with atherosclerosis and autoimmunity

(2016) S.C. Gominak   MEDICAL HYPOTHESES

The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis

(2016) E Thiele Orberg et al.   Mucosal Immunology

Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease

(2016) Francesca Pistollato et al.   NUTRITION REVIEWS

The healthy human microbiome

(2016) Jason Lloyd-Price et al.   Genome Medicine

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

T4 Phage Tail Adhesin Gp12 Counteracts LPS-Induced Inflammation In Vivo

(2016) Paulina Miernikiewicz et al.   Frontiers in Microbiology

Phage Therapy: Combating Infections with Potential for Evolving from Merely a Treatment for Complications to Targeting Diseases

(2016) Andrzej Górski et al.   Frontiers in Microbiology

Dysbiosis May Trigger Autoimmune Diseases via Inappropriate Post-Translational Modification of Host Proteins

(2016) Aaron Lerner et al.   Frontiers in Microbiology

Systematic Information to Health-Care Professionals about Vaccination Guidelines Improves Adherence in Patients With Inflammatory Bowel Disease in Anti-TNFα Therapy

(2015) Katrine R Christensen et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease

(2015) Aaron Lerner et al.   AUTOIMMUNITY REVIEWS

Intracerebroventricular injection of propionic acid, an enteric metabolite implicated in autism, induces social abnormalities that do not differ between seizure-prone (FAST) and seizure-resistant (SLOW) rats

(2015) Sandy R. Shultz et al.   BEHAVIOURAL BRAIN RESEARCH

Metabolism Links Bacterial Biofilms and Colon Carcinogenesis

(2015) Caroline H. Johnson et al.   Cell Metabolism

Gut Dysbiosis Is Linked to HypertensionNovelty and Significance

(2015) Tao Yang et al.   HYPERTENSION

Cross-talk between bile acids and intestinal microbiota in host metabolism and health

(2015) Yang-fan Nie et al.   Journal of Zhejiang University-SCIENCE B

Colonic bacterial composition in Parkinson's disease

(2015) Ali Keshavarzian et al.   MOVEMENT DISORDERS

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Microbiota Controls the Homeostasis of Glial Cells in the Gut Lamina Propria

(2015) Panagiotis S. Kabouridis et al.   NEURON

Burden of Clostridium difficile Infection in the United States

(2015) Fernanda C. Lessa et al.   NEW ENGLAND JOURNAL OF MEDICINE

Building the microbiome in health and disease: niche construction and social conflict in bacteria

(2015) Luke McNally et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Structural insight into effector proteins of Gram-negative bacterial pathogens that modulate the phosphoproteome of their host

(2015) Andrey M. Grishin et al.   PROTEIN SCIENCE

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

(2015) M. Vetizou et al.   SCIENCE

Disruption of the Gut Microbiome: Clostridium difficile Infection and the Threat of Antibiotic Resistance

(2015) Priscilla Johanesen et al.   Genes

Double-blind, randomised, placebo-controlled intervention trial to evaluate the effects of Bifidobacterium longum CECT 7347 in children with newly diagnosed coeliac disease

(2014) Marta Olivares et al.   BRITISH JOURNAL OF NUTRITION

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

(2014) Filipe De Vadder et al.   CELL

Gut Microbiota Promote Hematopoiesis to Control Bacterial Infection

(2014) Arya Khosravi et al.   Cell Host & Microbe

Vitamin B 12 as a Modulator of Gut Microbial Ecology

(2014) Patrick H. Degnan et al.   Cell Metabolism

Gut Dysbiosis and Detection of “Live Gut Bacteria” in Blood of Japanese Patients With Type 2 Diabetes

(2014) Junko Sato et al.   DIABETES CARE

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

(2014) Madhukumar Venkatesh et al.   IMMUNITY

Nutrient-sensing nuclear receptors coordinate autophagy

(2014) Jae Man Lee et al.   NATURE

The SLE Transcriptome Exhibits Evidence of Chronic Endotoxin Exposure and Has Widespread Dysregulation of Non-Coding and Coding RNAs

(2014) Lihua Shi et al.   PLoS One

Secondary bile acids: an underrecognized cause of colon cancer

(2014) Hana Ajouz et al.   World Journal of Surgical Oncology

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

(2014) Casey M. Theriot et al.   Nature Communications

Outcomes of salvage therapy for steroid-refractory acute severe ulcerative colitis: ciclosporin vs. infliximab

(2013) A. Croft et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study

(2013) Mora Murri et al.   BMC Medicine

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

Analysis of Fecal Lactobacillus Community Structure in Patients with Early Rheumatoid Arthritis

(2013) Xiaofei Liu et al.   CURRENT MICROBIOLOGY

Endotoxicity of Lipopolysaccharide as a Determinant of T-Cell−Mediated Colitis Induction in Mice

(2013) Kerstin Gronbach et al.   GASTROENTEROLOGY

A decrease of the butyrate-producing speciesRoseburia hominisandFaecalibacterium prausnitziidefines dysbiosis in patients with ulcerative colitis

(2013) Kathleen Machiels et al.   GUT

Bacteriophages in Gut Samples From Pediatric Crohn’s Disease Patients

(2013) Josef Wagner et al.   INFLAMMATORY BOWEL DISEASES

Dysbiosis Signature of Fecal Microbiota in Colorectal Cancer Patients

(2013) Na Wu et al.   MICROBIAL ECOLOGY

Control of pathogens and pathobionts by the gut microbiota

(2013) Nobuhiko Kamada et al.   NATURE IMMUNOLOGY

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Intestinal microbiota influence the early postnatal development of the enteric nervous system

(2013) J. Collins et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis

(2013) Brian G. Feagan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

(2013) Jose U Scher et al.   eLife

Metabolic Profiling of the Impact of Oligofructose-Enriched Inulin in Crohn’s Disease Patients: A Double-Blinded Randomized Controlled Trial

(2013) Vicky De Preter et al.   Clinical and Translational Gastroenterology

Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APC Min/+ mice

(2012) Yinghui Li et al.   CARCINOGENESIS

The composition and metabolic activity of child gut microbiota demonstrate differential adaptation to varied nutrient loads in an in vitro model of colonic fermentation

(2012) Amanda N. Payne et al.   FEMS MICROBIOLOGY ECOLOGY

Gut Microbial Products Regulate Murine Gastrointestinal Motility via Toll-Like Receptor 4 Signaling

(2012) Mallappa Anitha et al.   GASTROENTEROLOGY

Intestinal colonization resistance

(2012) Trevor D. Lawley et al.   IMMUNOLOGY

Structural Determinants ofClostridium difficileToxin A Glucosyltransferase Activity

(2012) Rory N. Pruitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic kidney disease alters intestinal microbial flora

(2012) Nosratola D. Vaziri et al.   KIDNEY INTERNATIONAL

Temporal and spatial interplay of microbiota and intestinal mucosa drive establishment of immune homeostasis in conventionalized mice

(2012) Sahar El Aidy et al.   Mucosal Immunology

A framework for human microbiome research

(2012)   NATURE

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome

(2012) H. Duboc et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Bifidobacterium longum CECT 7347 Modulates Immune Responses in a Gliadin-Induced Enteropathy Animal Model

(2012) José Moisés Laparra et al.   PLoS One

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Interaction between the intestinal microbiota and host in Clostridium difficile colonization resistance

(2012) Robert A. Britton et al.   TRENDS IN MICROBIOLOGY

Gastrointestinal flora and gastrointestinal status in children with autism – comparisons to typical children and correlation with autism severity

(2011) James B Adams et al.   BMC GASTROENTEROLOGY

The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon

(2011) Dallas R. Donohoe et al.   Cell Metabolism

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

(2011) M. Castellarin et al.   GENOME RESEARCH

Effect of oligofructose-enriched inulin (OF-IN) on bacterial composition and disease activity of patients with Crohn's disease: results from a double-blinded randomised controlled trial: Table 1

(2011) Marie Joossens et al.   GUT

Unraveling the Ties between Celiac Disease and Intestinal Microbiota

(2011) Yolanda Sanz et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers

(2011) Tingting Wang et al.   ISME Journal

B-Group vitamin production by lactic acid bacteria - current knowledge and potential applications

(2011) J.G. LeBlanc et al.   JOURNAL OF APPLIED MICROBIOLOGY

The Prevalence of Gastrointestinal Problems in Children Across the United States With Autism Spectrum Disorders From Families With Multiple Affected Members

(2011) Lulu W. Wang et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

A unique homologue of the eukaryotic protein-modifier ubiquitin present in the bacterium Bacteroides fragilis, a predominant resident of the human gastrointestinal tract

(2011) S. Patrick et al.   MICROBIOLOGY-SGM

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Prebiotic Effects of Wheat Arabinoxylan Related to the Increase in Bifidobacteria, Roseburia and Bacteroides/Prevotella in Diet-Induced Obese Mice

(2011) Audrey M. Neyrinck et al.   PLoS One

Immunomodulatory Effects of Lactobacillus casei Administration in a Mouse Model of Gliadin-Sensitive Enteropathy

(2011) R. D’Arienzo et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria

(2010) Chin Wen Png et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The prevalence of celiac disease in Europe: Results of a centralized, international mass screening project

(2010) Kirsi Mustalahti et al.   ANNALS OF MEDICINE

Intestinal dysbiosis and reduced immunoglobulin-coated bacteria associated with coeliac disease in children

(2010) Giada De Palma et al.   BMC MICROBIOLOGY

Live probiotic Bifidobacterium lactis bacteria inhibit the toxic effects induced by wheat gliadin in epithelial cell culture

(2010) K. Lindfors et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Short-Chain Fatty Acids Regulate the Enteric Neurons and Control Gastrointestinal Motility in Rats

(2010) Rodolphe Soret et al.   GASTROENTEROLOGY

A Pyrosequencing Study in Twins Shows That Gastrointestinal Microbial Profiles Vary With Inflammatory Bowel Disease Phenotypes

(2010) Ben P. Willing et al.   GASTROENTEROLOGY

Creating and characterizing communities of human gut microbes in gnotobiotic mice

(2010) Jeremiah J Faith et al.   ISME Journal

Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARγ-related adipogenesis in the white adipose tissue of high-fat diet-fed mice

(2010) Evelyne M. Dewulf et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Tumor Necrosis Factor-α Mediates the Blood–Brain Barrier Dysfunction Induced by Activated Microglia in Mouse Brain Microvascular Endothelial Cells

(2010) Tsuyoshi Nishioku et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression

(2010) L. Desbonnet et al.   NEUROSCIENCE

Further evidence that the rs1858830 C variant in the promoter region of theMETgene is associated with autistic disorder

(2009) Pamela B. Jackson et al.   Autism Research

GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

(2009) M. Thangaraju et al.   CANCER RESEARCH

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Influence of breast milk polyamines on suckling rat immune system maturation

(2009) Francisco J. Pérez-Cano et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Bile Acids and Metabolic Regulation: Mechanisms and clinical responses to bile acid sequestration

(2009) B. Staels et al.   DIABETES CARE

Towards the human intestinal microbiota phylogenetic core

(2009) Julien Tap et al.   ENVIRONMENTAL MICROBIOLOGY

Reproducible Community Dynamics of the Gastrointestinal Microbiota following Antibiotic Perturbation

(2009) D. A. Antonopoulos et al.   INFECTION AND IMMUNITY

Small-Intestinal Histopathology and Mortality Risk in Celiac Disease

(2009) Jonas F. Ludvigsson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Interaction between Phenolics and Gut Microbiota: Role in Human Health

(2009) María V. Selma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bile acids as regulatory molecules

(2009) Phillip B. Hylemon et al.   JOURNAL OF LIPID RESEARCH

Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism☆

(2009) Mar Larrosa et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Enteric defensins are essential regulators of intestinal microbial ecology

(2009) Nita H Salzman et al.   NATURE IMMUNOLOGY

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

(2009) Shaoguang Wu et al.   NATURE MEDICINE

Distinct Genetic Risk Based on Association of MET in Families With Co-occurring Autism and Gastrointestinal Conditions

(2009) D. B. Campbell et al.   PEDIATRICS

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Dysbiosis in inflammatory bowel disease: a role for bacteriophages?

(2008) P Lepage et al.   GUT

Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease

(2008) Nobito Higuchi et al.   HEPATOLOGY RESEARCH

Bile Salts and Glycine as Cogerminants for Clostridium difficile Spores

(2008) J. A. Sorg et al.   JOURNAL OF BACTERIOLOGY

Bifidobacterium strains suppress in vitro the pro-inflammatory milieu triggered by the large intestinal microbiota of coeliac patients

(2008) Marcela Medina et al.   Journal of Inflammation-London

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibiotic-Associated Diarrhea: Candidate Organisms other than Clostridium Difficile

(2008) Hyun Joo Song et al.   KOREAN JOURNAL OF INTERNAL MEDICINE