Molecular Mechanisms of Action of Novel Psychoactive Substances (NPS). A New Threat for Young Drug Users with Forensic-Toxicological Implications

How μ-opioid receptor recognizes fentanyl

(2021) Quynh N. Vo et al.   Nature Communications

Cannabidiol in Neurological and Neoplastic Diseases: Latest Developments on the Molecular Mechanism of Action

(2021) Marcin Ożarowski et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structure–Activity Relationship Study of Psychostimulant Synthetic Cathinones Reveals Nanomolar Antagonist Potency of α-Pyrrolidinohexiophenone at Human Muscarinic M2 Receptors

(2020) Yiming Chen et al.   ACS Chemical Neuroscience

Positive Allosteric Modulation of the 5-HT1A Receptor by Indole-Based Synthetic Cannabinoids Abused by Humans

(2020) Hideaki Yano et al.   ACS Chemical Neuroscience

25C-NBF, a new psychoactive substance, has addictive and neurotoxic potential in rodents

(2020) Kwang-Hyun Hur et al.   ARCHIVES OF TOXICOLOGY

Designer drugs: mechanism of action and adverse effects

(2020) Dino Luethi et al.   ARCHIVES OF TOXICOLOGY

The Effects of Intramuscular Naloxone Dose on Mu Receptor Displacement of Carfentanil in Rhesus Monkeys

(2020) Peter J. H. Scott et al.   MOLECULES

Drug trends and harm related to new psychoactive substances (NPS) in Sweden from 2010 to 2016: Experiences from the STRIDA project

(2020) Anders Helander et al.   PLoS One

Post-Mortem Toxicology: A Systematic Review of Death Cases Involving Synthetic Cannabinoid Receptor Agonists

(2020) Arianna Giorgetti et al.   Frontiers in Psychiatry

In vitro functional characterization of a panel of non-fentanyl opioid new psychoactive substances

(2020) Marthe M. Vandeputte et al.   ARCHIVES OF TOXICOLOGY

Assessment of structure-activity relationships and biased agonism at the Mu opioid receptor of novel synthetic opioids using a novel, stable bio-assay platform

(2020) Lakshmi Vasudevan et al.   BIOCHEMICAL PHARMACOLOGY

The Novel Psychoactive Substance Cumyl-CH-MEGACLONE: Human Phase-I Metabolism, Basic Pharmacological Characterization, and Comparison to Other Synthetic Cannabinoid Receptor Agonists with a γ-Carboline-1-one Core

(2020) Belal Haschimi et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Fentanyl but not Morphine Interacts with Nonopioid Recombinant Human Neurotransmitter Receptors and Transporters

(2020) Randy Torralva et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Two newly-emerging substituted phenethylamines MAL and BOD induce differential psychopharmacological effects in rodents

(2020) Raly James Perez Custodio et al.   JOURNAL OF PSYCHOPHARMACOLOGY

In vitro and in vivo pharmacological characterization of the synthetic opioid MT-45

(2020) S Bilel et al.   NEUROPHARMACOLOGY

Detrimental effects of the ‘bath salt’ methylenedioxypyrovalerone on social play behavior in male rats

(2020) Sara Schiavi et al.   NEUROPSYCHOPHARMACOLOGY

Four Synthetic Cathinones: 3-Chloromethcathinone, 4-Chloromethcathinone, 4-Fluoro-α-Pyrrolidinopentiophenone, and 4-Methoxy-α-Pyrrolidinopentiophenone Produce Changes in the Spontaneous Locomotor Activity and Motor Performance in Mice with Varied Profiles

(2020) Jakub Wojcieszak et al.   NEUROTOXICITY RESEARCH

Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity

(2020) Anna Pinson et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Exploring Stereochemical and Conformational Requirements at Cannabinoid Receptors for Synthetic Cannabinoids Related to SDB-006, 5F-SDB-006, CUMYL-PICA, and 5F-CUMYL-PICA

(2020) Adam Ametovski et al.   ACS Chemical Neuroscience

The neuropharmacology of cannabinoid receptor ligands in central signaling pathways

(2020) Tibor M. Brunt et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Molecular Pharmacology of Synthetic Cannabinoids: Delineating CB1 Receptor-Mediated Cell Signaling

(2020) Kenneth B. Walsh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synthetic cannabinoids enhanced ethanol-induced motor impairments through reduction of central glutamate neurotransmission

(2020) Masahiko Funada et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

U-47700 and Its Analogs: Non-Fentanyl Synthetic Opioids Impacting the Recreational Drug Market

(2020) Michael H. Baumann et al.   Brain Sciences

Neurochemical and Behavioral Characterization after Acute and Repeated Exposure to Novel Synthetic Cannabinoid Agonist 5-MDMB-PICA

(2020) Aurora Musa et al.   Brain Sciences

Psychopharmacological characterization of an emerging drug of abuse, a synthetic opioid U-47700, in adult zebrafish

(2020) Tatiana O. Kolesnikova et al.   BRAIN RESEARCH BULLETIN

Cannabinoid Ligands Targeting TRP Channels

(2019) Chanté Muller et al.   Frontiers in Molecular Neuroscience

Effects of the synthetic cannabinoid 5F-AMB on anxiety and recognition memory in mice

(2019) Shiho Ito et al.   PSYCHOPHARMACOLOGY

The Synthetic Cathinone Psychostimulant α-PPP Antagonizes Serotonin 5-HT2A Receptors: In Vitro and In Vivo Evidence

(2019) Yiming Chen et al.   Drug Testing and Analysis

Synthetic Cannabinoids and Cardiac Arrhythmia Risk: Review of the Literature

(2019) Hayriye Mihrimah Ozturk et al.   Cardiovascular Toxicology

Death cases involving certain new psychoactive substances: A review of the literature

(2019) Michael Kraemer et al.   FORENSIC SCIENCE INTERNATIONAL

para-Trifluoromethyl-methcathinone is an allosteric modulator of the serotonin transporter

(2019) Marco Niello et al.   NEUROPHARMACOLOGY

Pharmacological characterization of the aminorex analogs 4-MAR, 4,4′-DMAR, and 3,4-DMAR

(2019) Anna Rickli et al.   NEUROTOXICOLOGY

Metabolic Pathways and Potencies of New Fentanyl Analogs

(2019) Maurice Wilde et al.   Frontiers in Pharmacology

CUMYL-4CN-BINACA Is an Efficacious and Potent Pro-Convulsant Synthetic Cannabinoid Receptor Agonist

(2019) Richard C. Kevin et al.   Frontiers in Pharmacology

Opioid‐sparing effects of cannabinoids on morphine analgesia: participation of CB 1 and CB 2 receptors

(2019) Xiaohong Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Acute and repeated administration of MDPV increases aggressive behavior in mice: forensic implications

(2019) Fabio De-Giorgio et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Synthetic cannabinoids and their impact on neurodevelopmental processes

(2019) João Alexandre et al.   ADDICTION BIOLOGY

In vitro determination of the CB1 efficacy of illicit synthetic cannabinoids

(2019) Shivani Sachdev et al.   BRITISH JOURNAL OF PHARMACOLOGY

DARK Classics in Chemical Neuroscience: NBOMes

(2019) Christian B. M. Poulie et al.   ACS Chemical Neuroscience

25B‐NBOMe, a novel N ‐2‐methoxybenzyl‐phenethylamine (NBOMe) derivative, may induce rewarding and reinforcing effects via a dopaminergic mechanism: Evidence of abuse potential

(2019) Raly James Perez Custodio et al.   ADDICTION BIOLOGY

A novel designer drug, 25N-NBOMe, exhibits abuse potential via the dopaminergic system in rodents

(2019) Jee-Yeon Seo et al.   BRAIN RESEARCH BULLETIN

Report on a novel emerging class of highly potent benzimidazole NPS opioids: chemical and in vitro functional characterization of isotonitazene

(2019) Peter Blanckaert et al.   Drug Testing and Analysis

DARK Classics in Chemical Neuroscience: Synthetic Cannabinoids (Spice/K2)

(2019) Adam Worob et al.   ACS Chemical Neuroscience

Opioid analgesic drugs and serotonin toxicity (syndrome): mechanisms, animal models, and links to clinical effects

(2018) Brian A. Baldo   ARCHIVES OF TOXICOLOGY

Opioid-induced inhibition of the human 5-HT and noradrenaline transporters in vitro : link to clinical reports of serotonin syndrome

(2018) Anna Rickli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pro-psychotic effects of synthetic cannabinoids: interactions with central dopamine, serotonin, and glutamate systems

(2018) William E. Fantegrossi et al.   DRUG METABOLISM REVIEWS

The chemistry and pharmacology of synthetic cannabinoid SDB-006 and its regioisomeric fluorinated and methoxylated analogs

(2018) Samuel D. Banister et al.   Drug Testing and Analysis

Effects of the new psychoactive substances diclofensine, diphenidine, and methoxphenidine on monoaminergic systems

(2018) Dino Luethi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Abuse of fentanyl: An emerging problem to face

(2018) Katarzyna Kuczyńska et al.   FORENSIC SCIENCE INTERNATIONAL

Pharmacological evaluation of new constituents of “Spice”: synthetic cannabinoids based on indole, indazole, benzimidazole and carbazole scaffolds

(2018) Clara T. Schoeder et al.   Forensic Toxicology

Molecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICA

(2018) Thomas F. Gamage et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

“Ecstasy” to addiction: Mechanisms and reinforcing effects of three synthetic cathinone analogs of MDMA

(2018) Sean B. Dolan et al.   NEUROPHARMACOLOGY

Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace

(2018) Michael H. Baumann et al.   NEUROPHARMACOLOGY

Relative reinforcing effects of second-generation synthetic cathinones: Acquisition of self-administration and fixed ratio dose-response curves in rats

(2018) Brenda M. Gannon et al.   NEUROPHARMACOLOGY

Locomotor and reinforcing effects of pentedrone, pentylone and methylone in rats

(2018) Mehrak Javadi-Paydar et al.   NEUROPHARMACOLOGY

Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review

(2018) Patil Armenian et al.   NEUROPHARMACOLOGY

The synthetic cannabinoid 5F-AMB changes the balance between excitation and inhibition of layer V pyramidal neurons in the mouse medial prefrontal cortex

(2018) Masaki Domoto et al.   PSYCHOPHARMACOLOGY

Activity-Based Detection and Bioanalytical Confirmation of a Fatal Carfentanil Intoxication

(2018) Annelies Cannaert et al.   Frontiers in Pharmacology

Pharmacotoxicology of Non-fentanyl Derived New Synthetic Opioids

(2018) Renata Solimini et al.   Frontiers in Pharmacology

In Vitro Neurochemical Assessment of Methylphenidate and Its “Legal High” Analogs 3,4-CTMP and Ethylphenidate in Rat Nucleus Accumbens and Bed Nucleus of the Stria Terminalis

(2018) Colin Davidson et al.   Frontiers in Psychiatry

Repeated Exposure to the “Spice” Cannabinoid JWH-018 Induces Tolerance and Enhances Responsiveness to 5-HT1A Receptor Stimulation in Male Rats

(2018) Joshua S. Elmore et al.   Frontiers in Psychiatry

Synthesis and pharmacology of new psychoactive substance 5F-CUMYL-P7AICA, a scaffold hopping analogue of synthetic cannabinoid receptor agonists 5F-CUMYL-PICA and 5F-CUMYL-PINACA

(2018) Samuel D. Banister et al.   Drug Testing and Analysis

Full Title: Analytical quantification, intoxication case series, and pharmacological mechanism of action for N -ethylnorpentylone (N -ethylpentylone or ephylone)

(2018) Jose Luiz Costa et al.   Drug Testing and Analysis

Effect of cannabinoid receptor agonists on isolated rat atria

(2018) Simran Maggo et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Effects of repeated treatment with methcathinone, mephedrone, and fenfluramine on intracranial self-stimulation in rats

(2018) J. A. Suyama et al.   PSYCHOPHARMACOLOGY

Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ9-THC

(2018) Rachel D. Hutchison et al.   Frontiers in Pharmacology

Cannabinoid exposure during pregnancy and its impact on immune function

(2018) Catherine Dong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Application of an activity-based receptor bioassay to investigate the in vitro activity of selected indole- and indazole-3-carboxamide-based synthetic cannabinoids at CB1 and CB2 receptors

(2018) Carolina Noble et al.   Drug Testing and Analysis

The search for the “next” euphoric non-fentanil novel synthetic opioids on the illicit drugs market: current status and horizon scanning

(2018) Kirti Kumari Sharma et al.   Forensic Toxicology

Independent elevation of peripheral oxytocin concentrations and reduction in cognitive empathy during 4-fluoroamphetamine intoxication

(2018) Patrick C. Dolder et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice

(2018) Catheryn D. Wilson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Pharmacological Research as a Key Component in Mitigating the Opioid Overdose Crisis

(2018) Michael H. Baumann et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Comparison of electroencephalogram (EEG) response to MDPV versus the hallucinogenic drugs MK-801 and ketamine in rats

(2018) Ibrahim M. Shokry et al.   EXPERIMENTAL NEUROLOGY

Evaluation of carboxamide-type synthetic cannabinoids as CB1/CB2 receptor agonists: difference between the enantiomers

(2017) Takahiro Doi et al.   Forensic Toxicology

Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies

(2017) Isabella Canazza et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Fentanyl novel derivative-related deaths

(2017) Arianna Giorgetti et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Misuse of Novel Synthetic Opioids

(2017) Matthew P. Prekupec et al.   Journal of Addiction Medicine

Chiral Resolution and Enantioselectivity of Synthetic Cathinones: A Brief Review

(2017) Bárbara Silva et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Apparent Affinity Estimates and Reversal of the Effects of Synthetic Cannabinoids AM-2201, CP-47,497, JWH-122, and JWH-250 by Rimonabant in Rhesus Monkeys

(2017) Lenka Hruba et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Ephenidine: A new psychoactive agent with ketamine-like NMDA receptor antagonist properties

(2017) Heather Kang et al.   NEUROPHARMACOLOGY

ACPA and JWH-133 modulate the vascular tone of superior mesenteric arteries through cannabinoid receptors, BK Ca channels, and nitric oxide dependent mechanisms

(2017) Evelyn López-Dyck et al.   Pharmacological Reports

The synthetic cannabinoid WIN-55,212 induced-apoptosis in cytotrophoblasts cells by a mechanism dependent on CB1 receptor

(2017) Marta Almada et al.   TOXICOLOGY

Synthetic Pot: Not Your Grandfather’s Marijuana

(2017) Benjamin M. Ford et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Psychostimulant Effect of the Synthetic Cannabinoid JWH-018 and AKB48: Behavioral, Neurochemical, and Dopamine Transporter Scan Imaging Studies in Mice

(2017) Andrea Ossato et al.   Frontiers in Psychiatry

Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues

(2016) Samuel D. Banister et al.   ACS Chemical Neuroscience

Comparing rewarding and reinforcing properties between ‘bath salt’ 3,4-methylenedioxypyrovalerone (MDPV) and cocaine using ultrasonic vocalizations in rats

(2016) Steven J. Simmons et al.   ADDICTION BIOLOGY

Detection and Activity Profiling of Synthetic Cannabinoids and Their Metabolites with a Newly Developed Bioassay

(2016) Annelies Cannaert et al.   ANALYTICAL CHEMISTRY

The expression of methiopropamine-induced locomotor sensitization requires dopamine D2, but not D1, receptor activation in the rat

(2016) Hyung Shin Yoon et al.   BEHAVIOURAL BRAIN RESEARCH

Methoxetamine, a novel psychoactive substance with serious adverse pharmacological effects

(2016) Mary T. Zanda et al.   BEHAVIOURAL PHARMACOLOGY

Neurobiology of 3,4-methylenedioxypyrovalerone (MDPV) and α-pyrrolidinovalerophenone (α-PVP)

(2016) Richard A. Glennon et al.   BRAIN RESEARCH BULLETIN

Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and itsN-methoxy positional isomer,N-methoxymephedrone

(2016) Gavin McLaughlin et al.   Drug Testing and Analysis

Toxicological impact of JWH-018 and its phase I metabolite N-(3-hydroxypentyl) on human cell lines

(2016) Joana Couceiro et al.   FORENSIC SCIENCE INTERNATIONAL

Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice

(2016) Cornelius Hess et al.   Forensic Toxicology

Evaluation of first generation synthetic cannabinoids on binding at non-cannabinoid receptors and in a battery of in vivo assays in mice

(2016) Jenny L. Wiley et al.   NEUROPHARMACOLOGY

The new psychoactive substances 5-(2-aminopropyl)indole (5-IT) and 6-(2-aminopropyl)indole (6-IT) interact with monoamine transporters in brain tissue

(2016) Julie A. Marusich et al.   NEUROPHARMACOLOGY

Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies

(2016) Isabella Canazza et al.   PSYCHOPHARMACOLOGY

Self-administration and behavioral economics of second-generation synthetic cathinones in male rats

(2016) S.L. Huskinson et al.   PSYCHOPHARMACOLOGY

Δ9-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids in mice and rats

(2016) Michael B. Gatch et al.   PSYCHOPHARMACOLOGY

Cooling down the bath salts: Carvedilol attenuation of methylone and mephedrone mediated hyperthermia

(2016) Luke C. Zona et al.   TOXICOLOGY LETTERS

Synthetic cannabinoid, JWH-030, induces QT prolongation through hERG channel inhibition

(2016) Jaesuk Yun et al.   Toxicology Research

4-Fluoroamphetamine in the Netherlands: more than a one-night stand

(2015) Felix Linsen et al.   ADDICTION

Recent advances in the neuropsychopharmacology of serotonergic hallucinogens

(2015) Adam L. Halberstadt   BEHAVIOURAL BRAIN RESEARCH

Pharmacological profile of novel psychoactive benzofurans

(2015) Anna Rickli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cathinone Neurotoxicity (“The “3Ms”)

(2015) Steven Karch   Current Neuropharmacology

Effects of acute and repeated dosing of the synthetic cannabinoid CP55,940 on intracranial self-stimulation in mice

(2015) Travis W. Grim et al.   DRUG AND ALCOHOL DEPENDENCE

AH-7921: the list of new psychoactive opioids is expanded

(2015) Maria Katselou et al.   Forensic Toxicology

Cannabinoid-Induced Changes in the Activity of Electron Transport Chain Complexes of Brain Mitochondria

(2015) Namrata Singh et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

MAM-2201, a synthetic cannabinoid drug of abuse, suppresses the synaptic input to cerebellar Purkinje cells via activation of presynaptic CB1 receptors

(2015) Tomohiko Irie et al.   NEUROPHARMACOLOGY

Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice

(2015) A. Vigolo et al.   NEUROPHARMACOLOGY

Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signaling

(2015) M Liechti   SWISS MEDICAL WEEKLY

Amphetamines, new psychoactive drugs and the monoamine transporter cycle

(2015) Harald H. Sitte et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives

(2014) Linda D. Simmler et al.   BIOCHEMICAL PHARMACOLOGY

Cannabinoids inhibit cholinergic contraction in human airways through prejunctional CB1receptors

(2014) S Grassin-Delyle et al.   BRITISH JOURNAL OF PHARMACOLOGY

Characterization of a novel and potentially lethal designer drug(±)-cis-para-methyl-4-methylaminorex (4,4'-DMAR, or ‘Serotoni’)

(2014) Simon D. Brandt et al.   Drug Testing and Analysis

Direct effects of morphine but not of fentanyl-type opioids on human 5-HT3Areceptors in outside-out patch-clamp studies

(2014) T. Schaaf et al.   EUROPEAN JOURNAL OF PAIN

Effects of opioids on human serotonin transporters

(2014) M. Barann et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Pharmacology of novel synthetic stimulants structurally related to the “bath salts” constituent 3,4-methylenedioxypyrovalerone (MDPV)

(2014) Julie A. Marusich et al.   NEUROPHARMACOLOGY

Investigation of the in vitro toxicological properties of the synthetic cannabimimetic drug CP-47,497-C8

(2014) Verena J. Koller et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Toxicological profiles of selected synthetic cannabinoids showing high binding affinities to the cannabinoid receptor subtype CB1

(2013) Verena J. Koller et al.   ARCHIVES OF TOXICOLOGY

Substituted methcathinones differ in transporter and receptor interactions

(2013) Amy J. Eshleman et al.   BIOCHEMICAL PHARMACOLOGY

5-(2-Aminopropyl)indole (5-IT): a psychoactive substance used for recreational purposes is an inhibitor of human monoamine oxidase (MAO)

(2013) Tomás Herraiz et al.   Drug Testing and Analysis

Emerging Drugs of Abuse

(2013) Michael E. Nelson et al.   EMERGENCY MEDICINE CLINICS OF NORTH AMERICA

Mephedrone: Public health risk, mechanisms of action, and behavioral effects

(2013) Nicholas F. Dybdal-Hargreaves et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Bath salts and synthetic cathinones: An emerging designer drug phenomenon

(2013) Christopher L. German et al.   LIFE SCIENCES

Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ9-THC: Mechanism underlying greater toxicity?

(2013) William E. Fantegrossi et al.   LIFE SCIENCES

15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse

(2013) Pauline Charbogne et al.   NEUROPHARMACOLOGY

Monoamine transporter and receptor interaction profiles of a new series of designer cathinones

(2013) L.D. Simmler et al.   NEUROPHARMACOLOGY

The effects of benzofury (5-APB) on the dopamine transporter and 5-HT2-dependent vasoconstriction in the rat

(2013) Patrick Dawson et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors

(2013) Maheswari Rajasekaran et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death

(2013) Ken-ichi Tomiyama et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Pharmacological characterization of designer cathinonesin vitro

(2012) LD Simmler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neurochemical profiles of some novel psychoactive substances

(2012) Les Iversen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inhibition of 5-HT3 receptors-activated currents by cannabinoids in rat trigeminal ganglion neurons

(2012) Bo Shi et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Molecular Mechanisms of Opioid Receptor-dependent Signaling and Behavior

(2011) Ream Al-Hasani et al.   ANESTHESIOLOGY

Synthetic cannabinoid JWH-018 and psychosis: An explorative study

(2011) Susanna Every-Palmer   DRUG AND ALCOHOL DEPENDENCE

Journals publishing bio-medicolegal research in Europe

(2011) Rafael Boscolo-Berto et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

WIN55,212-2 induced deficits in spatial learning are mediated by cholinergic hypofunction

(2010) Lianne Robinson et al.   BEHAVIOURAL BRAIN RESEARCH

Non-CB1, Non-CB2 Receptors for Endocannabinoids, Plant Cannabinoids, and Synthetic Cannabimimetics: Focus on G-protein-coupled Receptors and Transient Receptor Potential Channels

(2009) Luciano De Petrocellis et al.   Journal of Neuroimmune Pharmacology

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE