Consideration of Gut Microbiome in Murine Models of Diseases

Gut microbiota impact on the peripheral immune response in non-alcoholic fatty liver disease related hepatocellular carcinoma

(2021) Jason Behary et al.   Nature Communications

The impact of interactions on invasion and colonization resistance in microbial communities

(2021) Helen M. Kurkjian et al.   PLoS Computational Biology

Exploring the Emerging Role of the Gut Microbiota and Tumor Microenvironment in Cancer Immunotherapy

(2021) Qin Qiu et al.   Frontiers in Immunology

The gut microbiome of laboratory mice: considerations and best practices for translational research

(2021) Aaron C. Ericsson et al.   MAMMALIAN GENOME

Impact of Dietary Flavanols on Microbiota, Immunity and Inflammation in Metabolic Diseases

(2021) María Ángeles Martín et al.   Nutrients

Polyphenols as Prebiotics in the Management of High-Fat Diet-Induced Obesity: A Systematic Review of Animal Studies

(2021) Mohanambal Moorthy et al.   Foods

Role of dietary polyphenols on gut microbiota, their metabolites and health benefits

(2021) S. Mithul Aravind et al.   FOOD RESEARCH INTERNATIONAL

Implications of the Gut Microbiome in Parkinson's Disease

(2020) Mohamed Elfil et al.   MOVEMENT DISORDERS

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

(2020) Aonghus Lavelle et al.   Nature Reviews Gastroenterology & Hepatology

Interaction between microbiota and immunity in health and disease

(2020) Danping Zheng et al.   CELL RESEARCH

The central role of gut microbiota in drug metabolism and personalized medicine

(2020) Gianni Colotti et al.   Future Medicinal Chemistry

Interaction between drugs and the gut microbiome

(2020) Rinse K Weersma et al.   GUT

The Gut Microbiota: Emerging Evidence in Autoimmune Diseases

(2020) Xuan Zhang et al.   TRENDS IN MOLECULAR MEDICINE

The Firmicutes/Bacteroidetes Ratio: A Relevant Marker of Gut Dysbiosis in Obese Patients?

(2020) Fabien Magne et al.   Nutrients

Specific gut microbiome signature predicts the early-stage lung cancer

(2020) Yajuan Zheng et al.   Gut Microbes

Integration of genomics, metagenomics, and metabolomics to identify interplay between susceptibility alleles and microbiota in adenoma initiation

(2020) Jacob E. Moskowitz et al.   BMC CANCER

Microbial Imidazole Propionate Affects Responses to Metformin through p38γ-Dependent Inhibitory AMPK Phosphorylation

(2020) Ara Koh et al.   Cell Metabolism

The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation

(2020) Chunliang Xu et al.   IMMUNITY

Potential therapeutic applications of the gut microbiome in obesity: from brain function to body detoxification

(2020) Béatrice S.-Y. Choi et al.   INTERNATIONAL JOURNAL OF OBESITY

Gut Microbiota and Liver Fibrosis: One Potential Biomarker for Predicting Liver Fibrosis

(2020) Zhiming Li et al.   Biomed Research International

Gut-liver axis modulation in fructose-fed mice: a role for PPAR-alpha and linagliptin

(2020) Flávia Maria Silva-Veiga et al.   JOURNAL OF ENDOCRINOLOGY

Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study)

(2020) Yifei Zhang et al.   Nature Communications

The Gut Microbiome Is Associated with Clinical Response to Anti–PD-1/PD-L1 Immunotherapy in Gastrointestinal Cancer

(2020) Zhi Peng et al.   Cancer Immunology Research

The Potential Gut Microbiota-Mediated Treatment Options for Liver Cancer

(2020) Chunye Zhang et al.   Frontiers in Oncology

Polymannuronic acid prevents dopaminergic neuronal loss via brain-gut-microbiota axis in Parkinson's disease model

(2020) Xiao-Li Dong et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The gut mycobiota: insights into analysis, environmental interactions and role in gastrointestinal diseases

(2019) Mathias L. Richard et al.   Nature Reviews Gastroenterology & Hepatology

The microbiome, cancer, and cancer therapy

(2019) Beth A. Helmink et al.   NATURE MEDICINE

Microbiome–metabolome reveals the contribution of gut–kidney axis on kidney disease

(2019) Yuan-Yuan Chen et al.   Journal of Translational Medicine

Microbes, metabolites, and the gut–lung axis

(2019) Anh Thu Dang et al.   Mucosal Immunology

Comparison of Co-housing and Littermate Methods for Microbiota Standardization in Mouse Models

(2019) Susan J. Robertson et al.   Cell Reports

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

(2019) Gil Sharon et al.   CELL

Littermate wanted: standardizing mouse gut microbiota requires more than cohousing

(2019) Ellen P. Neff   LAB ANIMAL

Uses for humanised mouse models in precision medicine for neurodegenerative disease

(2019) Remya R. Nair et al.   MAMMALIAN GENOME

Fecal microbiota transplantation to treat Parkinsonʼs disease with constipation

(2019) Hongli Huang et al.   MEDICINE

Gut Microbiota and Colonization Resistance against Bacterial Enteric Infection

(2019) Q. R. Ducarmon et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Mapping human microbiome drug metabolism by gut bacteria and their genes

(2019) Michael Zimmermann et al.   NATURE

Microbiota therapy acts via a regulatory T cell MyD88/RORγt pathway to suppress food allergy

(2019) Azza Abdel-Gadir et al.   NATURE MEDICINE

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

(2019) Clara Depommier et al.   NATURE MEDICINE

Long-term benefit of Microbiota Transfer Therapy on autism symptoms and gut microbiota

(2019) Dae-Wook Kang et al.   Scientific Reports

Type 1 Diabetes: an Association Between Autoimmunity, the Dynamics of Gut Amyloid-producing E. coli and Their Phages

(2019) George Tetz et al.   Scientific Reports

The Microbiome and Irritable Bowel Syndrome – A Review on the Pathophysiology, Current Research and Future Therapy

(2019) Pei Pei Chong et al.   Frontiers in Microbiology

Gut microbiome affects the response to anti-PD-1 immunotherapy in patients with hepatocellular carcinoma

(2019) Yi Zheng et al.   Journal for ImmunoTherapy of Cancer

The path toward using microbial metabolites as therapies

(2019) Hélène C. Descamps et al.   EBioMedicine

Therapeutic Opportunities in Inflammatory Bowel Disease: Mechanistic Dissection of Host-Microbiome Relationships

(2019) Damian R. Plichta et al.   CELL

The evolution of the use of faecal microbiota transplantation and emerging therapeutic indications

(2019) Jessica R Allegretti et al.   LANCET

The gut microbiome in neurological disorders

(2019) John F Cryan et al.   LANCET NEUROLOGY

The gut microbiota modulates differential adenoma suppression by B6/J and B6/N genetic backgrounds in ApcMin mice

(2019) Jacob E. Moskowitz et al.   MAMMALIAN GENOME

Gut microbiota depletion from early adolescence alters adult immunological and neurobehavioral responses in a mouse model of multiple sclerosis

(2019) Maryam Zeraati et al.   NEUROPHARMACOLOGY

Beneficial Effects of Dietary Polyphenols on Gut Microbiota and Strategies to Improve Delivery Efficiency

(2019) Amit Kumar Singh et al.   Nutrients

Induction of Intestinal Th17 Cells by Flagellins From Segmented Filamentous Bacteria

(2019) Yanling Wang et al.   Frontiers in Immunology

The role of gut microbiota in obesity, diabetes mellitus, and effect of metformin: new insights into old diseases

(2019) Alessia Pascale et al.   CURRENT OPINION IN PHARMACOLOGY

The Human Gut Microbiome: From Association to Modulation

(2018) Thomas S.B. Schmidt et al.   CELL

Dietary Interventions to Modulate the Gut Microbiome—How Far Away Are We From Precision Medicine

(2018) Francesca De Filippis et al.   INFLAMMATORY BOWEL DISEASES

The gut–liver axis and the intersection with the microbiome

(2018) Anupriya Tripathi et al.   Nature Reviews Gastroenterology & Hepatology

Microbiome: Gut microbiota sways response to cancer immunotherapy

(2018) Ashley York   NATURE REVIEWS MICROBIOLOGY

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

(2018) Vyara Matson et al.   SCIENCE

Multi-cohort analysis of colorectal cancer metagenome identified altered bacteria across populations and universal bacterial markers

(2018) Zhenwei Dai et al.   Microbiome

A Gut Commensal-Produced Metabolite Mediates Colonization Resistance to Salmonella Infection

(2018) Amanda Jacobson et al.   Cell Host & Microbe

Short-Chain Fatty Acids Manifest Stimulative and Protective Effects on Intestinal Barrier Function Through the Inhibition of NLRP3 Inflammasome and Autophagy

(2018) Yanhai Feng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome

(2018) Daria V. Zhernakova et al.   NATURE GENETICS

Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility

(2018) Towfique Raj et al.   NATURE GENETICS

Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis

(2018) Mingming Sun et al.   Nature Communications

The influence of caging, bedding, and diet on the composition of the microbiota in different regions of the mouse gut

(2018) Aaron C. Ericsson et al.   Scientific Reports

Development of outbred CD1 mouse colonies with distinct standardized gut microbiota profiles for use in complex microbiota targeted studies

(2018) Marcia L. Hart et al.   Scientific Reports

Segmented Filamentous Bacteria – Metabolism Meets Immunity

(2018) Grant A. Hedblom et al.   Frontiers in Microbiology

Butyrate Produced by Commensal Bacteria Down-Regulates Indolamine 2,3-Dioxygenase 1 (IDO-1) Expression via a Dual Mechanism in Human Intestinal Epithelial Cells

(2018) Camille Martin-Gallausiaux et al.   Frontiers in Immunology

Gut microbiome structure and metabolic activity in inflammatory bowel disease

(2018) Eric A. Franzosa et al.   Nature Microbiology

Gut microbiota functions: metabolism of nutrients and other food components

(2017) Ian Rowland et al.   EUROPEAN JOURNAL OF NUTRITION

Identification of an Intestinal Microbiota Signature Associated With Severity of Irritable Bowel Syndrome

(2017) Julien Tap et al.   GASTROENTEROLOGY

Homeostatic Immunity and the Microbiota

(2017) Yasmine Belkaid et al.   IMMUNITY

Association between the gut microbiota and mineral metabolism

(2017) Katarzyna Skrypnik et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Microbiota and reproducibility of rodent models

(2017) Craig L Franklin et al.   LAB ANIMAL

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

(2017) Wei Zhao et al.   NATURE GENETICS

Bifidobacteriumcan mitigate intestinal immunopathology in the context of CTLA-4 blockade

(2017) Feng Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical transformation of xenobiotics by the human gut microbiota

(2017) Nitzan Koppel et al.   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Gut microbiome interactions with drug metabolism, efficacy, and toxicity

(2017) Ian D. Wilson et al.   Translational Research

Gut microbiome in chronic kidney disease: challenges and opportunities

(2017) Anitha Nallu et al.   Translational Research

Making Mouse Models That Reflect Human Immune Responses

(2017) Lili Tao et al.   TRENDS IN IMMUNOLOGY

The gut microbiome in atherosclerotic cardiovascular disease

(2017) Zhuye Jie et al.   Nature Communications

Variable Colonization after Reciprocal Fecal Microbiota Transfer between Mice with Low and High Richness Microbiota

(2017) Aaron C. Ericsson et al.   Frontiers in Microbiology

Differing Complex Microbiota Alter Disease Severity of the IL-10−/− Mouse Model of Inflammatory Bowel Disease

(2017) Marcia L. Hart et al.   Frontiers in Microbiology

Dynamics of the human gut microbiome in inflammatory bowel disease

(2017) Jonas Halfvarson et al.   Nature Microbiology

Modulation of Gut Microbiota in Pathological States

(2017) Yulan Wang et al.   Engineering

Bacteriophages as potential new mammalian pathogens

(2017) George V. Tetz et al.   Scientific Reports

Gut microbiome alterations in Alzheimer’s disease

(2017) Nicholas M. Vogt et al.   Scientific Reports

Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract

(2016) Jenessa A. Winston et al.   ANAEROBE

Using the mouse to model human disease: increasing validity and reproducibility

(2016) Monica J. Justice et al.   Disease Models & Mechanisms

A Novel Microbiome Therapeutic Increases Gut Microbial Diversity and Prevents RecurrentClostridium difficileInfection

(2016) Sahil Khanna et al.   JOURNAL OF INFECTIOUS DISEASES

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

The effect of host genetics on the gut microbiome

(2016) Marc Jan Bonder et al.   NATURE GENETICS

Breakthroughs in the treatment and prevention of Clostridium difficile infection

(2016) Larry K. Kociolek et al.   Nature Reviews Gastroenterology & Hepatology

The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility

(2016) Tugba Ozdal et al.   Nutrients

Genome-guided design of a defined mouse microbiota that confers colonization resistance against Salmonella enterica serovar Typhimurium

(2016) Sandrine Brugiroux et al.   Nature Microbiology

Fecal Microbiota Transplantation forClostridium difficileInfection

(2015) Dimitri Drekonja et al.   ANNALS OF INTERNAL MEDICINE

The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

(2015) Aleksandar D. Kostic et al.   Cell Host & Microbe

Commensal Microbiome Promotes Resistance to Local and Systemic Infections

(2015) Qiu-Shui He et al.   CHINESE MEDICAL JOURNAL

BALB/c and C57BL/6 Mice Differ in Polyreactive IgA Abundance, which Impacts the Generation of Antigen-Specific IgA and Microbiota Diversity

(2015) Floris Fransen et al.   IMMUNITY

Protective effects of butyrate on intestinal ischemia–reperfusion injury in rats

(2015) Yingli Qiao et al.   JOURNAL OF SURGICAL RESEARCH

How bacterial pathogens colonize their hosts and invade deeper tissues

(2015) David Ribet et al.   MICROBES AND INFECTION

The human gut mycobiome: pitfalls and potentials--a mycologists perspective

(2015) M. J. Suhr et al.   MYCOLOGIA

Growth and host interaction of mouse segmented filamentous bacteria in vitro

(2015) Pamela Schnupf et al.   NATURE

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

(2015) M. Vetizou et al.   SCIENCE

Gut microbiome development along the colorectal adenoma–carcinoma sequence

(2015) Qiang Feng et al.   Nature Communications

Effects of Vendor and Genetic Background on the Composition of the Fecal Microbiota of Inbred Mice

(2015) Aaron C. Ericsson et al.   PLoS One

Immunoglobulin A Coating Identifies Colitogenic Bacteria in Inflammatory Bowel Disease

(2014) Noah W. Palm et al.   CELL

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

Probiotic Mix VSL#3 Is Effective Adjunctive Therapy for Mild to Moderately Active Ulcerative Colitis

(2014) Houssam E. Mardini et al.   INFLAMMATORY BOWEL DISEASES

Structural and functional changes in the gut microbiota associated to Clostridium difficile infection

(2014) Ana E. Pérez-Cobas et al.   Frontiers in Microbiology

Animal models of human disease: Challenges in enabling translation

(2013) Paul McGonigle et al.   BIOCHEMICAL PHARMACOLOGY

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

Intestinal Dysbiosis and Depletion of Butyrogenic Bacteria in Clostridium difficile Infection and Nosocomial Diarrhea

(2013) V. C. Antharam et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Quantitatively Different, yet Qualitatively Alike: A Meta-Analysis of the Mouse Core Gut Microbiome with a View towards the Human Gut Microbiome

(2013) Lukasz Krych et al.   PLoS One

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

(2013) Michelle M Simon et al.   GENOME BIOLOGY

Alterations in composition and diversity of the intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome

(2012) I. M. Carroll et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Mispairing C57BL/6 Substrains of Genetically Engineered Mice and Wild-Type Controls Can Lead to Confounding Results as It Did in Studies of JNK2 in Acetaminophen and Concanavalin A Liver Injury

(2011) Mohammed Bourdi et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

(2011) A. D. Kostic et al.   GENOME RESEARCH

The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen’s virulence factors, and the host’s mucosal immune response

(2011) Patrick Kaiser et al.   IMMUNOLOGICAL REVIEWS

Intestinal Microbiota Promote Enteric Virus Replication and Systemic Pathogenesis

(2011) S. K. Kuss et al.   SCIENCE

Dysbiosis of fecal microbiota in Crohnʼs disease patients as revealed by a custom phylogenetic microarray

(2010) Seungha Kang et al.   INFLAMMATORY BOWEL DISEASES

Diet-induced Obesity in Two C57BL/6 Substrains With Intact or Mutant Nicotinamide Nucleotide Transhydrogenase (Nnt) Gene

(2010) Anthony Nicholson et al.   Obesity

Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

(2010) B. D. Wallace et al.   SCIENCE

The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea

(2010) Kathrin Endt et al.   PLoS Pathogens

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Secretory IgA-Mediated Neutralization of Shigella flexneri Prevents Intestinal Tissue Destruction by Down-Regulating Inflammatory Circuits

(2009) S. Boullier et al.   JOURNAL OF IMMUNOLOGY

Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers

(2009) Luying Peng et al.   JOURNAL OF NUTRITION

Human genetic variation and its contribution to complex traits

(2009) Kelly A. Frazer et al.   NATURE REVIEWS GENETICS

The Biology of Intestinal Immunoglobulin A Responses

(2008) Andrea Cerutti et al.   IMMUNITY

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE