The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen’s virulence factors, and the host’s mucosal immune response

The Adaptor Protein CIKS/Act1 Is Essential for IL-25-Mediated Allergic Airway Inflammation

(2014) E. Claudio et al.   JOURNAL OF IMMUNOLOGY

Immunoglobulin Responses at the Mucosal Interface

(2011) Andrea Cerutti et al.   Annual Review of Immunology

Eukaryotic signaling pathways targeted by Salmonella effector protein AvrA in intestinal infection in vivo

(2011) Xingyin Liu et al.   BMC MICROBIOLOGY

TLR Signaling Is Required for Salmonella typhimurium Virulence

(2011) Nicholas Arpaia et al.   CELL

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Activation of a RhoA/Myosin II-Dependent but Arp2/3 Complex-Independent Pathway Facilitates Salmonella Invasion

(2011) Jan Hänisch et al.   Cell Host & Microbe

Salmonella Typhimurium diarrhea: switching the mucosal epithelium from homeostasis to defense

(2011) Patrick Kaiser et al.   CURRENT OPINION IN IMMUNOLOGY

Impact of Usp18 and IFN signaling in Salmonella-induced typhlitis

(2011) E Richer et al.   GENES AND IMMUNITY

Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

(2011) Markus B. Geuking et al.   IMMUNITY

Protective Role of Akt2 in Salmonella enterica Serovar Typhimurium-Induced Gastroenterocolitis

(2011) Winnie W. S. Kum et al.   INFECTION AND IMMUNITY

Early MyD88-Dependent Induction of Interleukin-17A Expression during Salmonella Colitis

(2011) A. Marijke Keestra et al.   INFECTION AND IMMUNITY

Antibiotic Treatment Alters the Colonic Mucus Layer and Predisposes the Host to ExacerbatedCitrobacter rodentium-Induced Colitis

(2011) M. Wlodarska et al.   INFECTION AND IMMUNITY

The Chromobacterium violaceum type III effector CopE, a guanine nucleotide exchange factor for Rac1 and Cdc42, is involved in bacterial invasion of epithelial cells and pathogenesis

(2011) Tsuyoshi Miki et al.   MOLECULAR MICROBIOLOGY

Bifidobacteria can protect from enteropathogenic infection through production of acetate

(2011) Shinji Fukuda et al.   NATURE

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Fecal matters

(2011) Roxanne Palmer   NATURE MEDICINE

Identification of an innate T helper type 17 response to intestinal bacterial pathogens

(2011) Kaoru Geddes et al.   NATURE MEDICINE

Shifting the balance: antibiotic effects on host–microbiota mutualism

(2011) Benjamin P. Willing et al.   NATURE REVIEWS MICROBIOLOGY

The Intestinal Microbiota Plays a Role in Salmonella-Induced Colitis Independent of Pathogen Colonization

(2011) Rosana B. R. Ferreira et al.   PLoS One

Novel Murine Infection Models Provide Deep Insights into the “Ménage à Trois” of Campylobacter jejuni, Microbiota and Host Innate Immunity

(2011) Stefan Bereswill et al.   PLoS One

Salmonella-Induced Mucosal Lectin RegIIIβ Kills Competing Gut Microbiota

(2011) Christian Stelter et al.   PLoS One

Stromal IFN-γR-Signaling Modulates Goblet Cell Function During Salmonella Typhimurium Infection

(2011) Pascal Songhet et al.   PLoS One

The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

(2011) J. L. Round et al.   SCIENCE

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

(2011) A. Puel et al.   SCIENCE

The ecology of nasal colonization of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus: the role of competition and interactions with host's immune response

(2010) Elisa Margolis et al.   BMC MICROBIOLOGY

The Phosphoinositide Phosphatase SopB Manipulates Membrane Surface Charge and Trafficking of the Salmonella-Containing Vacuole

(2010) Malina A. Bakowski et al.   Cell Host & Microbe

Within-Host Competition Drives Selection for the Capsule Virulence Determinant of Streptococcus pneumoniae

(2010) Elena S. Lysenko et al.   CURRENT BIOLOGY

Mechanisms controlling pathogen colonization of the gut

(2010) Bärbel Stecher et al.   CURRENT OPINION IN MICROBIOLOGY

A global network of coexisting microbes from environmental and whole-genome sequence data

(2010) S. Chaffron et al.   GENOME RESEARCH

Infected Cell in Trouble: Bystander Cells Ring the Bell

(2010) Wolf-Dietrich Hardt   IMMUNITY

Cell-Cell Propagation of NF-κB Transcription Factor and MAP Kinase Activation Amplifies Innate Immunity against Bacterial Infection

(2010) Christoph Alexander Kasper et al.   IMMUNITY

Absence of Poly(ADP-Ribose) Polymerase 1 Delays the Onset of Salmonella enterica Serovar Typhimurium-Induced Gut Inflammation

(2010) M. Altmeyer et al.   INFECTION AND IMMUNITY

Salmonella entericaSerovar Typhimurium Binds to HeLa Cells via Fim-Mediated Reversible Adhesion and Irreversible Type Three Secretion System 1-Mediated Docking

(2010) Benjamin Misselwitz et al.   INFECTION AND IMMUNITY

Nod1 and Nod2 Regulation of Inflammation in the Salmonella Colitis Model

(2010) K. Geddes et al.   INFECTION AND IMMUNITY

Roles of spvB and spvC in S. Typhimurium colitis via the alternative pathway

(2010) Rina Käppeli et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans

(2010) Carles Ubeda et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology

(2010) Sofia Buonocore et al.   NATURE

Gut inflammation provides a respiratory electron acceptor for Salmonella

(2010) Sebastian E. Winter et al.   NATURE

In Macrophages, Caspase-1 Activation by SopE and the Type III Secretion System-1 of S. Typhimurium Can Proceed in the Absence of Flagellin

(2010) Claudia Hoffmann et al.   PLoS One

Bacteria Penetrate the Inner Mucus Layer before Inflammation in the Dextran Sulfate Colitis Model

(2010) Malin E. V. Johansson et al.   PLoS One

IL-17A/F-Signaling Does Not Contribute to the Initial Phase of Mucosal Inflammation Triggered by S. Typhimurium

(2010) Pascal Songhet et al.   PLoS One

Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting

(2010) N. Joller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Induction of lamina propria Th17 cells by intestinal commensal bacteria

(2010) Koji Atarashi et al.   VACCINE

Potentiation of Epithelial Innate Host Responses by Intercellular Communication

(2010) Tamas Dolowschiak et al.   PLoS Pathogens

Caspase-1 Activation via Rho GTPases: A Common Theme in Mucosal Infections?

(2010) Andreas J. Müller et al.   PLoS Pathogens

Regulatory T Cell Suppressive Potency Dictates the Balance between Bacterial Proliferation and Clearance during Persistent Salmonella Infection

(2010) Tanner M. Johanns et al.   PLoS Pathogens

Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

(2010) Kirk S. B. Bergstrom et al.   PLoS Pathogens

Like Will to Like: Abundances of Closely Related Species Can Predict Susceptibility to Intestinal Colonization by Pathogenic and Commensal Bacteria

(2010) Bärbel Stecher et al.   PLoS Pathogens

The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea

(2010) Kathrin Endt et al.   PLoS Pathogens

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

The S. Typhimurium Effector SopE Induces Caspase-1 Activation in Stromal Cells to Initiate Gut Inflammation

(2009) Andreas J. Müller et al.   Cell Host & Microbe

Lipocalin-2 Resistance Confers an Advantage to Salmonella enterica Serotype Typhimurium for Growth and Survival in the Inflamed Intestine

(2009) Manuela Raffatellu et al.   Cell Host & Microbe

Pathogenesis of enteric Salmonella infections

(2009) Guntram A Grassl et al.   CURRENT OPINION IN GASTROENTEROLOGY

Intestinal Lamina Propria Dendritic Cell Subsets Have Different Origin and Functions

(2009) Chen Varol et al.   IMMUNITY

Immune Responses to the Microbiota at the Intestinal Mucosal Surface

(2009) Breck A. Duerkop et al.   IMMUNITY

Accelerated Type III Secretion System 2-Dependent Enteropathogenesis by a Salmonella enterica Serovar Enteritidis PT4/6 Strain

(2009) M. Suar et al.   INFECTION AND IMMUNITY

O-Antigen-Negative Salmonella enterica Serovar Typhimurium Is Attenuated in Intestinal Colonization but Elicits Colitis in Streptomycin-Treated Mice

(2009) K. Ilg et al.   INFECTION AND IMMUNITY

Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts

(2009) T. D. Lawley et al.   INFECTION AND IMMUNITY

Metagenomic analyses reveal antibiotic-induced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasis

(2009) D A Hill et al.   Mucosal Immunology

Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics

(2009) Zhiwei Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Life in the inflamed intestine, Salmonella style

(2009) Renato L. Santos et al.   TRENDS IN MICROBIOLOGY

Clostridium difficile Toxin CDT Induces Formation of Microtubule-Based Protrusions and Increases Adherence of Bacteria

(2009) Carsten Schwan et al.   PLoS Pathogens

Salmonella Typhimurium Type III Secretion Effectors Stimulate Innate Immune Responses in Cultured Epithelial Cells

(2009) Vincent M. Bruno et al.   PLoS Pathogens

Selective Inhibition of Type III Secretion Activated Signaling by the Salmonella Effector AvrA

(2009) Fangyong Du et al.   PLoS Pathogens

Active Caspase-1 Is a Regulator of Unconventional Protein Secretion

(2008) Martin Keller et al.   CELL

Salmonella AvrA Coordinates Suppression of Host Immune and Apoptotic Defenses via JNK Pathway Blockade

(2008) Rheinallt M. Jones et al.   Cell Host & Microbe

Structure and Function of Salmonella SifA Indicate that Its Interactions with SKIP, SseJ, and RhoA Family GTPases Induce Endosomal Tubulation

(2008) Maikke B. Ohlson et al.   Cell Host & Microbe

Metabolic Diversity in Campylobacter jejuni Enhances Specific Tissue Colonization

(2008) Dirk Hofreuter et al.   Cell Host & Microbe

Nramp1 expression by dendritic cells modulates inflammatory responses duringSalmonellaTyphimurium infection

(2008) Yanet Valdez et al.   CELLULAR MICROBIOLOGY

Cooperation ofSalmonellapathogenicity islands 1 and 4 is required to breach epithelial barriers

(2008) Roman G. Gerlach et al.   CELLULAR MICROBIOLOGY

Motility allows S. Typhimurium to benefit from the mucosal defence

(2008) Bärbel Stecher et al.   CELLULAR MICROBIOLOGY

Nramp1 drives an accelerated inflammatory response duringSalmonella-induced colitis in mice

(2008) Yanet Valdez et al.   CELLULAR MICROBIOLOGY

Identification ofSalmonellaSPI-2 secretion system components required for SpvB-mediated cytotoxicity in macrophages and virulence in mice

(2008) Sara H. Browne et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Chronic Enteric Salmonella Infection in Mice Leads to Severe and Persistent Intestinal Fibrosis

(2008) Guntram A. Grassl et al.   GASTROENTEROLOGY

IL-1, IL-18, and IL-33 families of cytokines

(2008) William P. Arend et al.   IMMUNOLOGICAL REVIEWS

Interleukin-15 and NK1.1+ Cells Provide Innate Protection against Acute Salmonella enterica Serovar Typhimurium Infection in the Gut and in Systemic Tissues

(2008) A. A. Ashkar et al.   INFECTION AND IMMUNITY

Interleukin-23 Orchestrates Mucosal Responses to Salmonella enterica Serotype Typhimurium in the Intestine

(2008) I. Godinez et al.   INFECTION AND IMMUNITY

Antibiotic-Induced Perturbations of the Intestinal Microbiota Alter Host Susceptibility to Enteric Infection

(2008) I. Sekirov et al.   INFECTION AND IMMUNITY

T Cells Help To Amplify Inflammatory Responses Induced by Salmonella enterica Serotype Typhimurium in the Intestinal Mucosa

(2008) I. Godinez et al.   INFECTION AND IMMUNITY

CsrA and CsrB are required for the post-transcriptional control of the virulence-associated effector protein AvrA of Salmonella enterica

(2008) Tobias Kerrinnes et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

SopB promotes phosphatidylinositol 3-phosphate formation onSalmonellavacuoles by recruiting Rab5 and Vps34

(2008) Gustavo V. Mallo et al.   JOURNAL OF CELL BIOLOGY

Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent stepin ΔinvG S. Typhimurium colitis

(2008) Siegfried Hapfelmeier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen-activated protein kinases

(2008) Piotr Mazurkiewicz et al.   MOLECULAR MICROBIOLOGY

Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits

(2008) Katharina Brandl et al.   NATURE

Self-destructive cooperation mediated by phenotypic noise

(2008) Martin Ackermann et al.   NATURE

A Model of Salmonella Colitis with Features of Diarrhea in SLC11A1 Wild-Type Mice

(2008) Heungjeong Woo et al.   PLoS One

Hierarchical Effector Protein Transport by the Salmonella Typhimurium SPI-1 Type III Secretion System

(2008) Brit Winnen et al.   PLoS One

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing

(2008) Les Dethlefsen et al.   PLOS BIOLOGY