Auranofin-Mediated NRF2 Induction Attenuates Interleukin 1 Beta Expression in Alveolar Macrophages

Selenium-independent antioxidant and anti-inflammatory effects of thioredoxin reductase inhibition in alveolar macrophages

(2020) Sara Staples et al.   LIFE SCIENCES

Recent Advances of Gold Compounds in Anticancer Immunity

(2020) Shuang Yue et al.   Frontiers in Chemistry

An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation

(2020) Sarmistha Saha et al.   MOLECULES

Thioredoxin Reductase-1 Inhibition Augments Endogenous Glutathione-Dependent Antioxidant Responses in Experimental Bronchopulmonary Dysplasia

(2019) Stephanie B. Wall et al.   Oxidative Medicine and Cellular Longevity

Role of Nrf2 and Its Activators in Respiratory Diseases

(2019) Qinmei Liu et al.   Oxidative Medicine and Cellular Longevity

Protective mechanism of sulforaphane in Nrf2 and anti-lung injury in ARDS rabbits

(2018) Zongjian Sun et al.   Experimental and Therapeutic Medicine

Thioredoxin Reductase Inhibition Attenuates Neonatal Hyperoxic Lung Injury and Enhances Nuclear Factor E2–Related Factor 2 Activation

(2016) Qian Li et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

(2016) Eri H. Kobayashi et al.   Nature Communications

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

(2015) Joanna D. Wardyn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Inhibiting I B -NF B signaling attenuates the expression of select pro-inflammatory genes

(2015) S. McKenna et al.   JOURNAL OF CELL SCIENCE

Auranofin: Repurposing an Old Drug for a Golden New Age

(2015) Christine Roder et al.   Drugs in research & development

Suppression of the pro-inflammatory NLRP3/interleukin-1β pathway in macrophages by the thioredoxin reductase inhibitor auranofin

(2014) Elina Isakov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Transcription Factors NRF2 and NF-κB Are Coordinated Effectors of the Rho Family, GTP-binding Protein RAC1 during Inflammation

(2014) Antonio Cuadrado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IκBβ-Mediated NF-κB Activation Confers Protection Against Hyperoxic Lung Injury

(2013) Katherine A Michaelis et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Thioredoxin Reductase-1 Inhibitor Aurothioglucose Attenuates Lung Injury and Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome

(2013) Rodney D. Britt et al.   ANTIOXIDANTS & REDOX SIGNALING

Thioredoxin Reductase Inhibition Elicits Nrf2-Mediated Responses in Clara Cells: Implications for Oxidant-Induced Lung Injury

(2012) Morgan L. Locy et al.   ANTIOXIDANTS & REDOX SIGNALING

Lipopolysaccharide-induced Cyclooxygenase-2 Expression in Mouse Transformed Clara Cells

(2012) Rodney D. Britt Jr. et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

IκBβ acts to inhibit and activate gene expression during the inflammatory response

(2010) Ping Rao et al.   NATURE

Disruption of Nrf2 Impairs the Resolution of Hyperoxia-Induced Acute Lung Injury and Inflammation in Mice

(2009) N. M. Reddy et al.   JOURNAL OF IMMUNOLOGY

Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

(2008) David Michaelson et al.   JOURNAL OF CELL BIOLOGY