Biomechanical Properties of Cancer Cells

Transformation of SH-SY5Y cell line into neuron-like cells: Investigation of electrophysiological and biomechanical changes

(2021) Meryem Şahin et al.   NEUROSCIENCE LETTERS

Effect of F-actin and Microtubules on Cellular Mechanical Behavior Studied Using Atomic Force Microscope and an Image Recognition-Based Cytoskeleton Quantification Approach

(2020) Yi Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cytotoxic and biomechanical effects of clinical dosing schemes of paclitaxel on neurons and cancer cells

(2020) Chou-Ching K. Lin et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications

(2020) Yuanyuan Zhang et al.   Cellular & Molecular Immunology

Direct evidence that tumor cells soften when navigating confined spaces

(2020) Carmela Rianna et al.   MOLECULAR BIOLOGY OF THE CELL

Nanomechanics and Histopathology as Diagnostic Tools to Characterize Freshly Removed Human Brain Tumors

(2020) Mateusz Cieśluk et al.   International Journal of Nanomedicine

Label‐Free Imaging of Cholesterol Assemblies Reveals Hidden Nanomechanics of Breast Cancer Cells

(2020) Andra C. Dumitru et al.   Advanced Science

In search of the correlation between nanomechanical and biomolecular properties of prostate cancer cells with different metastatic potential

(2020) Katarzyna Pogoda et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mechanical Adaptability of Tumor Cells in Metastasis

(2020) Valentin Gensbittel et al.   DEVELOPMENTAL CELL

Single Cell Mechanotype and Associated Molecular Changes in Urothelial Cell Transformation and Progression

(2020) Weibo Yu et al.   Frontiers in Cell and Developmental Biology

Advances in micropipette aspiration: applications in cell biomechanics, models and extended studies

(2019) Blanca González-Bermúdez et al.   BIOPHYSICAL JOURNAL

The relationship between metastatic potential and in vitro mechanical properties of osteosarcoma cells

(2019) Claude N. Holenstein et al.   MOLECULAR BIOLOGY OF THE CELL

Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization

(2019) Dominika A. Rudzka et al.   JOURNAL OF CELL SCIENCE

Lab on a tip: Applications of functional atomic force microscopy for the study of electrical properties in biology

(2019) Ling-Zhi Cheong et al.   Acta Biomaterialia

Cell swelling, softening and invasion in a three-dimensional breast cancer model

(2019) Yu Long Han et al.   Nature Physics

The Role of Tumor Microenvironment in Genomic Instability of Malignant Tumors

(2019) F. Gizem Sonugür et al.   Frontiers in Genetics

Intrafibrillar, bone-mimetic collagen mineralization regulates breast cancer cell adhesion and migration

(2018) Siyoung Choi et al.   BIOMATERIALS

Biomechanical measurement and analysis of colchicine-induced effects on cells by nanoindentation using an atomic force microscope

(2018) Lanjiao Liu et al.   JOURNAL OF BIOMECHANICS

Mechanotransduction in tumor progression: The dark side of the force

(2018) Florence Broders-Bondon et al.   JOURNAL OF CELL BIOLOGY

Epithelial-mesenchymal transition softens head and neck cancer cells to facilitate migration in 3D environments

(2018) Yin-Quan Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mechanical forces in skin disorders

(2018) Chao-Kai Hsu et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Clinical utility of circulating non-coding RNAs — an update

(2018) Simone Anfossi et al.   Nature Reviews Clinical Oncology

Profiling circulating tumour cells and other biomarkers of invasive cancers

(2018) Mahla Poudineh et al.   Nature Biomedical Engineering

Cancer cells’ ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential

(2018) Lena Wullkopf et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanical, nanomorphological and biological reconstruction of early‑stage apoptosis in HeLa cells induced by cytochalasin�B

(2018) Xuelian Su et al.   ONCOLOGY REPORTS

Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility

(2018) Amanpreet Kaur et al.   Cancer Discovery

Atomic Force Microscopy in Characterizing Cell Mechanics for Biomedical Applications: A Review

(2017) Mi Li et al.   IEEE TRANSACTIONS ON NANOBIOSCIENCE

Nanoscale imaging and force probing of biomolecular systems using atomic force microscopy: from single molecules to living cells

(2017) Mi Li et al.   Nanoscale

Prognostic and predictive biomarkers in breast cancer: Past, present and future

(2017) Andrea Nicolini et al.   SEMINARS IN CANCER BIOLOGY

Inertial Microfluidic Cell Stretcher (iMCS): Fully Automated, High-Throughput, and Near Real-Time Cell Mechanotyping

(2017) Yanxiang Deng et al.   Small

Mechanical mismatch between Ras transformed and untransformed epithelial cells

(2017) Corinne Gullekson et al.   Soft Matter

Actin stress fiber organization promotes cell stiffening and proliferation of pre-invasive breast cancer cells

(2017) Sandra Tavares et al.   Nature Communications

Enlightening discriminative network functional modules behind Principal Component Analysis separation in differential-omic science studies

(2017) Sara Ciucci et al.   Scientific Reports

Atomic force microscopy indentation and inverse analysis for non-linear viscoelastic identification of breast cancer cells

(2016) Nhung Nguyen et al.   MATHEMATICAL BIOSCIENCES

Nano-mechanical signature of brain tumours

(2016) Gabriele Ciasca et al.   Nanoscale

Quantitative analysis of the cell-surface roughness and viscoelasticity for breast cancer cells discrimination using atomic force microscopy

(2016) Yuhua Wang et al.   SCANNING

Mechanical Signals Inhibit Growth of a Grafted Tumor In Vivo: Proof of Concept

(2016) Rémy Brossel et al.   PLoS One

Correlating confocal microscopy and atomic force indentation reveals metastatic cancer cells stiffen during invasion into collagen I matrices

(2016) Jack R. Staunton et al.   Scientific Reports

Reprint of: Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria

(2015) S. Suresh et al.   Acta Biomaterialia

Nano-mechanical Reinforcement in Drug-Resistant Ovarian Cancer Cells

(2015) Young Ho Seo et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

ELASTICITY OF DIFFERENTIATED AND UNDIFFERENTIATED HUMAN NEUROBLASTOMA CELLS CHARACTERIZED BY ATOMIC FORCE MICROSCOPY

(2015) SHIJIA ZHAO et al.   Journal of Mechanics in Medicine and Biology

AFM-Based Study of Fullerenol (C 60 (OH) 24 )-Induced Changes of Elasticity in Living SMCC-7721 Cells

(2015) Yang Liu et al.   Journal of the Mechanical Behavior of Biomedical Materials

A monolithic glass chip for active single-cell sorting based on mechanical phenotyping

(2015) Christoph Faigle et al.   LAB ON A CHIP

The nanomechanical signature of liver cancer tissues and its molecular origin

(2015) Mengxin Tian et al.   Nanoscale

Mechanical phenotype of cancer cells: cell softening and loss of stiffness sensing

(2015) Hsi-Hui Lin et al.   Oncotarget

Cell jamming: Collective invasion of mesenchymal tumor cells imposed by tissue confinement

(2014) Anna Haeger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence

(2014) Kristin M. Riching et al.   BIOPHYSICAL JOURNAL

The role of Rho GTPase in cell stiffness and cisplatin resistance in ovarian cancer cells

(2014) Shivani Sharma et al.   Integrative Biology

Oncogenes induce a vimentin filament collapse mediated by HDAC6 that is linked to cell stiffness

(2014) L.-S. Z. Rathje et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanomechanical biomarkers of single circulating tumor cells for detection of castration resistant prostate cancer

(2014) Pawel Osmulski et al.   PROSTATE

Single-Molecule Reconstruction of Oligonucleotide Secondary Structure by Atomic Force Microscopy

(2014) Alice Pyne et al.   Small

The softening of human bladder cancer cells happens at an early stage of the malignancy process

(2014) Jorge R Ramos et al.   Beilstein Journal of Nanotechnology

Macroscopic Stiffness of Breast Tumors Predicts Metastasis

(2014) Joseph Fenner et al.   Scientific Reports

Investigating dynamic structural and mechanical changes of neuroblastoma cells associated with glutamate-mediated neurodegeneration

(2014) Yuqiang Fang et al.   Scientific Reports

Mechanotransduction at focal adhesions: from physiology to cancer development

(2013) Jihye Seong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Increased plasticity of the stiffness of melanoma cells correlates with their acquisition of metastatic properties

(2013) Gilles Weder et al.   Nanomedicine-Nanotechnology Biology and Medicine

Mechanics Meets Medicine

(2013) J. Guck et al.   Science Translational Medicine

Quantitative Diagnosis of Malignant Pleural Effusions by Single-Cell Mechanophenotyping

(2013) H. T. K. Tse et al.   Science Translational Medicine

Actin filaments play a primary role for structural integrity and viscoelastic response in cells

(2012) Alperen N. Ketene et al.   Integrative Biology

Higher cell stiffness indicating lower metastatic potential in B16 melanoma cell variants and in (−)-epigallocatechin gallate-treated cells

(2012) Tatsuro Watanabe et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Keratins Mediate Localization of Hemidesmosomes and Repress Cell Motility

(2012) Kristin Seltmann et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Comparison of mechanical properties of normal and malignant thyroid cells

(2012) Meenakshi Prabhune et al.   MICRON

The nanomechanical signature of breast cancer

(2012) Marija Plodinec et al.   Nature Nanotechnology

AFM-Detected Apoptotic Changes in Morphology and Biophysical Property Caused by Paclitaxel in Ishikawa and HeLa Cells

(2012) Kyung Sook Kim et al.   PLoS One

Cell Stiffness Is a Biomarker of the Metastatic Potential of Ovarian Cancer Cells

(2012) Wenwei Xu et al.   PLoS One

Microfluidics separation reveals the stem-cell-like deformability of tumor-initiating cells

(2012) W. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical Stiffness Grades Metastatic Potential in Patient Tumor Cells and in Cancer Cell Lines

(2011) V. Swaminathan et al.   CANCER RESEARCH

Photocatalytic and phototoxic properties of TiO2-based nanofilaments: ESR and AFM assays

(2011) Katarzyna Pierzchała et al.   Nanotoxicology

Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction

(2010) Denise N. Johnson-Lyles et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Extracellular Matrix Stiffness and Architecture Govern Intracellular Rheology in Cancer

(2009) Erin L. Baker et al.   BIOPHYSICAL JOURNAL

Oral Cancer Diagnosis by Mechanical Phenotyping

(2009) T. W. Remmerbach et al.   CANCER RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Endothelial actin and cell stiffness is modulated by substrate stiffness in 2D and 3D

(2009) Fitzroy J. Byfield et al.   JOURNAL OF BIOMECHANICS

Effects of fullerenol C60(OH)24 on the frequency of micronuclei and chromosome aberrations in CHO-K1 cells

(2009) Jasminka Mrđanović et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Compaction of cell shape occurs before decrease of elasticity in CHO-K1 cells treated with actin cytoskeleton disrupting drug cytochalasin D

(2009) Christian Schulze et al.   CELL MOTILITY AND THE CYTOSKELETON

MR Elastography of Liver Tumors: Preliminary Results

(2008) Sudhakar K. Venkatesh et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Measurement of elastic properties of prostate cancer cells using AFM

(2008) Elsa Correia Faria et al.   ANALYST

AFM indentation study of breast cancer cells

(2008) Q.S. Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AFM-based analysis of human metastatic cancer cells

(2008) Sarah E Cross et al.   NANOTECHNOLOGY