Profiling circulating tumour cells and other biomarkers of invasive cancers

Enhanced Isolation and Release of Circulating Tumor Cells Using Nanoparticle Binding and Ligand Exchange in a Microfluidic Chip

(2017) Myoung-Hwan Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Circulating and disseminated tumor cells: harbingers or initiators of metastasis?

(2017) Arko Dasgupta et al.   Molecular Oncology

Integrating liquid biopsies into the management of cancer

(2017) Giulia Siravegna et al.   Nature Reviews Clinical Oncology

Current approaches for avoiding the limitations of circulating tumor cells detection methods—implications for diagnosis and treatment of patients with solid tumors

(2017) Artur Kowalik et al.   Translational Research

Profiling protein expression in circulating tumour cells using microfluidic western blotting

(2017) Elly Sinkala et al.   Nature Communications

Circulating Tumor DNA as Biomarkers for Cancer Detection

(2017) Xiao Han et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Clinical prospects of liquid biopsies

(2017) Catherine Alix-Panabières et al.   Nature Biomedical Engineering

Profiling Functional and Biochemical Phenotypes of Circulating Tumor Cells Using a Two-Dimensional Sorting Device

(2016) Mahla Poudineh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stem-like features of cancer cells on their way to metastasis

(2016) Sofia Gkountela et al.   Biology Direct

Imaging Tumor Metabolism to Assess Disease Progression and Treatment Response

(2016) K. N. Timm et al.   CLINICAL CANCER RESEARCH

Accession of Tumor Heterogeneity by Multiplex Transcriptome Profiling of Single Circulating Tumor Cells

(2016) Tobias M. Gorges et al.   CLINICAL CHEMISTRY

Circulating Tumor Cells: A Review of Non-EpCAM-Based Approaches for Cell Enrichment and Isolation

(2016) M. T. Gabriel et al.   CLINICAL CHEMISTRY

Decline in Circulating Tumor Cell Count and Treatment Outcome in Advanced Prostate Cancer

(2016) David Lorente et al.   EUROPEAN UROLOGY

A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells

(2016) G.E. Hvichia et al.   INTERNATIONAL JOURNAL OF CANCER

Circulating tumor cell clusters: What we know and what we expect (Review)

(2016) Yupeng Hong et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Epithelial-mesenchymal plasticity in circulating tumor cells

(2016) Catherine Alix-Panabières et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Circulating tumor cell technologies

(2016) Meghaan M. Ferreira et al.   Molecular Oncology

Metastatic colonization by circulating tumour cells

(2016) Joan Massagué et al.   NATURE

Integrated digital error suppression for improved detection of circulating tumor DNA

(2016) Aaron M Newman et al.   NATURE BIOTECHNOLOGY

Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer

(2016) Louise Carter et al.   NATURE MEDICINE

Nanoscale lateral displacement arrays for the separation of exosomes and colloids down to 20 nm

(2016) Benjamin H. Wunsch et al.   Nature Nanotechnology

Tracking the dynamics of circulating tumour cell phenotypes using nanoparticle-mediated magnetic ranking

(2016) Mahla Poudineh et al.   Nature Nanotechnology

Clusters of circulating tumor cells traverse capillary-sized vessels

(2016) Sam H. Au et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy

(2016) C. Alix-Panabieres et al.   Cancer Discovery

Blood-Based Analysis of Circulating Cell-Free DNA and Tumor Cells for Early Cancer Detection

(2016) Klaus Pantel   PLOS MEDICINE

Association of AR-V7 on Circulating Tumor Cells as a Treatment-Specific Biomarker With Outcomes and Survival in Castration-Resistant Prostate Cancer

(2016) Howard I. Scher et al.   JAMA Oncology

Identification of Circulating Tumor DNA for the Early Detection of Small-cell Lung Cancer

(2016) Lynnette Fernandez-Cuesta et al.   EBioMedicine

The Challenges of Detecting Circulating Tumor Cells in Sarcoma

(2016) Marta Tellez-Gabriel et al.   Frontiers in Oncology

A novel approach for next-generation sequencing of circulating tumor cells

(2016) Stephanie S. Yee et al.   Molecular Genetics & Genomic Medicine

Single-Cell Codetection of Metabolic Activity, Intracellular Functional Proteins, and Genetic Mutations from Rare Circulating Tumor Cells

(2015) Yu Zhang et al.   ANALYTICAL CHEMISTRY

Beyond the Capture of Circulating Tumor Cells: Next-Generation Devices and Materials

(2015) Brenda J. Green et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diagnostic technologies for circulating tumour cells and exosomes

(2015) H. Shao et al.   BIOSCIENCE REPORTS

Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease

(2015) Eleonor Olsson et al.   EMBO Molecular Medicine

The potential of tumor-derived exosomes for noninvasive cancer monitoring

(2015) Theresa L Whiteside   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Challenges for CTC-based liquid biopsies: low CTC frequency and diagnostic leukapheresis as a potential solution

(2015) Nikolas H. Stoecklein et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Circulating Cell-Free Tumour DNA in the Management of Cancer

(2015) Glenn Francis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Importance of circulating tumor cells in newly diagnosed colorectal cancer

(2015) GUUS VAN DALUM et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Epithelial-Mesenchymal Transition Phenotype Is Associated with Clinicopathological Factors That Indicate Aggressive Biological Behavior and Poor Clinical Outcomes in Invasive Breast Cancer

(2015) Young Kyung Bae et al.   Journal of Breast Cancer

Do Circulating Tumor Cells, Exosomes, and Circulating Tumor Nucleic Acids Have Clinical Utility?

(2015) Bert Gold et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Challenges in circulating tumor cell detection by the CellSearch system

(2015) Kiki C. Andree et al.   Molecular Oncology

Velocity valleys enable efficient capture and spatial sorting of nanoparticle-bound cancer cells

(2015) Justin D. Besant et al.   Nanoscale

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

A microfluidic device for label-free, physical capture of circulating tumor cell clusters

(2015) A Fatih Sarioglu et al.   NATURE METHODS

The biology of circulating tumor cells

(2015) K Pantel et al.   ONCOGENE

Interrogating Circulating Microsomes and Exosomes Using Metal Nanoparticles

(2015) Yi-Ge Zhou et al.   Small

Classification of Circulating Tumor Cells by Epithelial-Mesenchymal Transition Markers

(2015) Shiyang Wu et al.   PLoS One

Overexpression of MMP Family Members Functions as Prognostic Biomarker for Breast Cancer Patients: A Systematic Review and Meta-Analysis

(2015) Fanghui Ren et al.   PLoS One

Emerging Role of Nanomaterials in Circulating Tumor Cell Isolation and Analysis

(2014) Hyeun Joong Yoon et al.   ACS Nano

Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

(2014) Nicola Aceto et al.   CELL

Biology, detection, and clinical implications of circulating tumor cells

(2014) S. A. Joosse et al.   EMBO Molecular Medicine

Circulating tumor DNA and circulating tumor cells in metastatic triple negative breast cancer patients

(2014) Jordan Madic et al.   INTERNATIONAL JOURNAL OF CANCER

Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data

(2014) François-Clément Bidard et al.   LANCET ONCOLOGY

Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor

(2014) Hyungsoon Im et al.   NATURE BIOTECHNOLOGY

Collective and individual migration following the epithelial–mesenchymal transition

(2014) Ian Y. Wong et al.   NATURE MATERIALS

Molecular analysis of circulating tumour cells—biology and biomarkers

(2014) Matthew G. Krebs et al.   Nature Reviews Clinical Oncology

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

(2014) Emmanuel S. Antonarakis et al.   NEW ENGLAND JOURNAL OF MEDICINE

NanoFlares for the detection, isolation, and culture of live tumor cells from human blood

(2014) Tiffany L. Halo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Chemokines in Cancer

(2014) M. T. Chow et al.   Cancer Immunology Research

Versatile Immunomagnetic Nanocarrier Platform for Capturing Cancer Cells

(2013) Chun-Hsien Wu et al.   ACS Nano

Micropatterned Sensing Hydrogels Integrated with Reconfigurable Microfluidics for Detecting Protease Release from Cells

(2013) Kyung Jin Son et al.   ANALYTICAL CHEMISTRY

Programmable Interactions of Functionalized Single Bioparticles in a Dielectrophoresis-Based Microarray Chip

(2013) Melanie Abonnenc et al.   ANALYTICAL CHEMISTRY

Assembled gold nanoparticles on nitrogen-doped graphene for ultrasensitive electrochemical detection of matrix metalloproteinase-2

(2013) Guohai Yang et al.   CARBON

Prognostic Relevance of Viable Circulating Tumor Cells Detected by EPISPOT in Metastatic Breast Cancer Patients

(2013) J.-M. Ramirez et al.   CLINICAL CHEMISTRY

Capture of Viable Circulating Tumor Cells in the Liver of Colorectal Cancer Patients

(2013) E. Deneve et al.   CLINICAL CHEMISTRY

Epithelial-mesenchymal plasticity in carcinoma metastasis

(2013) J. H. Tsai et al.   GENES & DEVELOPMENT

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Platelets in Tumor Progression: A Host Factor That Offers Multiple Potential Targets in the Treatment of Cancer

(2013) Deva Sharma et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Technologies for label-free separation of circulating tumor cells: from historical foundations to recent developments

(2013) Chao Jin et al.   LAB ON A CHIP

Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay

(2013) Irène Baccelli et al.   NATURE BIOTECHNOLOGY

Sensitive capture of circulating tumour cells by functionalized graphene oxide nanosheets

(2013) Hyeun Joong Yoon et al.   Nature Nanotechnology

Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

(2013) Sarah-Jane Dawson et al.   NEW ENGLAND JOURNAL OF MEDICINE

In Vitro Model of Tumor Cell Extravasation

(2013) Jessie S. Jeon et al.   PLoS One

Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

(2013) M. Yu et al.   SCIENCE

Inertial Focusing for Tumor Antigen-Dependent and -Independent Sorting of Rare Circulating Tumor Cells

(2013) E. Ozkumur et al.   Science Translational Medicine

The Identification and Characterization of Breast Cancer CTCs Competent for Brain Metastasis

(2013) L. Zhang et al.   Science Translational Medicine

How does cancer cell metabolism affect tumor migration and invasion?

(2013) Tianyu Han et al.   Cell Adhesion & Migration

Tumor cell migration in complex microenvironments

(2012) William J. Polacheck et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Circulating Tumor Cells: Liquid Biopsy of Cancer

(2012) C. Alix-Panabieres et al.   CLINICAL CHEMISTRY

RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis

(2012) Min Yu et al.   NATURE

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Body fluid derived exosomes as a novel template for clinical diagnostics

(2011) Sascha Keller et al.   Journal of Translational Medicine

Quantitative Nanostructural and Single-Molecule Force Spectroscopy Biomolecular Analysis of Human-Saliva-Derived Exosomes

(2011) Shivani Sharma et al.   LANGMUIR

Mechanism of the Mesenchymal-Epithelial Transition and Its Relationship with Metastatic Tumor Formation

(2011) D. Yao et al.   MOLECULAR CANCER RESEARCH

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

(2011) S. C. Bendall et al.   SCIENCE

A Novel Platform for Detection of CK+ and CK- CTCs

(2011) C. V. Pecot et al.   Cancer Discovery

Detection of EpCAM-Negative and Cytokeratin-Negative Circulating Tumor Cells in Peripheral Blood

(2011) Stephen D. Mikolajczyk et al.   Journal of Oncology

Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting

(2010) Chrisostomi Gialeli et al.   FEBS Journal

Characterization of metastatic breast cancer patients with nondetectable circulating tumor cells

(2010) Michal Mego et al.   INTERNATIONAL JOURNAL OF CANCER

Isolation of circulating tumor cells using a microvortex-generating herringbone-chip

(2010) S. L. Stott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Label-free impedance detection of low levels of circulating endothelial progenitor cells for point-of-care diagnosis

(2009) Shi Yun Ng et al.   BIOSENSORS & BIOELECTRONICS

Epithelial-Mesenchymal Transition and Cell Cooperativity in Metastasis

(2009) T. Tsuji et al.   CANCER RESEARCH

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer micrometastases

(2009) Klaus Pantel et al.   Nature Reviews Clinical Oncology

Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device

(2009) A. H. Talasaz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Inhibition of Tumor Cell Intravasation and Subsequent Metastasis via Regulation of In Vivo Tumor Cell Motility by the Tetraspanin CD151

(2008) Andries Zijlstra et al.   CANCER CELL

Highly Efficient Circulating Tumor Cell Isolation from Whole Blood and Label-Free Enumeration Using Polymer-Based Microfluidics with an Integrated Conductivity Sensor

(2008) André A. Adams et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Focusing and continuous separation of cells in a microfluidic device using lateral dielectrophoresis

(2007) N DEMIERRE et al.   SENSORS AND ACTUATORS B-CHEMICAL