Mechanisms of Neurodegeneration in Various Forms of Parkinsonism—Similarities and Differences

Frequency of spinocerebellar ataxia mutations in patients with multiple system atrophy

(2021) Anna I. Wernick et al.   CLINICAL AUTONOMIC RESEARCH

T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease

(2020) Gregory P. Williams et al.   ACTA NEUROPATHOLOGICA

High-salt diet does not boost neuroinflammation and neurodegeneration in a model of α-synucleinopathy

(2020) Antonio Heras-Garvin et al.   Journal of Neuroinflammation

DNA damage and repair in Parkinson's disease: Recent advances and new opportunities

(2020) Claudia P. Gonzalez‐Hunt et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy

(2020) Mohammad Shahnawaz et al.   NATURE

Clinicopathologic and genetic features of multiple system atrophy with Lewy body disease

(2020) Shunsuke Koga et al.   BRAIN PATHOLOGY

Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration

(2020) Insup Choi et al.   Nature Communications

Biological links between traumatic brain injury and Parkinson’s disease

(2020) Vedad Delic et al.   Acta Neuropathologica Communications

Alpha‐Synuclein Oligomers and Neurofilament Light Chain in Spinal Fluid Differentiate Multiple System Atrophy from Lewy Body Synucleinopathies

(2020) Wolfgang Singer et al.   ANNALS OF NEUROLOGY

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models

(2020) Michiyo Iba et al.   Journal of Neuroinflammation

Spinocerebellar ataxia type 6 family with phenotypic overlap with Multiple System Atrophy

(2020) Rana Hanna Al-Shaikh et al.   Neurologia i Neurochirurgia Polska

Transcriptomic differences in MSA clinical variants

(2020) Alexandra Pérez-Soriano et al.   Scientific Reports

Circulating Inflammatory miRNAs Associated with Parkinson’s Disease Pathophysiology

(2020) Sara R. Oliveira et al.   Biomolecules

Neuroinflammation and Tau Colocalize in vivo in Progressive Supranuclear Palsy

(2020) Maura Malpetti et al.   ANNALS OF NEUROLOGY

Tau at the interface between neurodegeneration and neuroinflammation

(2020) Alessandro Didonna   GENES AND IMMUNITY

Inflammation in Experimental Models of α ‐Synucleinopathies

(2020) Ashley S. Harms et al.   MOVEMENT DISORDERS

Metabolic alterations in Parkinson’s disease astrocytes

(2020) Tuuli-Maria Sonninen et al.   Scientific Reports

Interleukin-17A: The Key Cytokine in Neurodegenerative Diseases

(2020) Junjue Chen et al.   Frontiers in Aging Neuroscience

Genetics of Progressive Supranuclear Palsy: A Review

(2020) Yafei Wen et al.   Journal of Parkinsons Disease

Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes

(2020) Hyuk Sung Kwon et al.   Translational Neurodegeneration

MAPT subhaplotypes in corticobasal degeneration: assessing associations with disease risk, severity of tau pathology, and clinical features

(2020) Rebecca R. Valentino et al.   Acta Neuropathologica Communications

Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose

(2019) Anna-Carin Hoffmann et al.   Scientific Reports

Microglia as modulators of exosomal alpha-synuclein transmission

(2019) Yun Xia et al.   Cell Death & Disease

Alpha-synuclein induces microglial migration via PKM2-dependent glycolysis

(2019) Hongfei Qiao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Increased immune activation by pathologic alpha‐synuclein in Parkinson's Disease

(2019) Veselin Grozdanov et al.   ANNALS OF NEUROLOGY

Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders

(2019) Allison J. Schaser et al.   Scientific Reports

Understanding the pathogenesis of multiple system atrophy: state of the art and future perspectives

(2019) Giacomo Monzio Compagnoni et al.   Acta Neuropathologica Communications

Interactions between iron and α-synuclein pathology in Parkinson's disease

(2019) Bingbing Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson’s disease and multiple system atrophy

(2019) Chiara Maria Giulia De Luca et al.   Translational Neurodegeneration

Parkinson disease

(2019) R. Balestrino et al.   EUROPEAN JOURNAL OF NEUROLOGY

Frontrunner in Translation: Progressive Supranuclear Palsy

(2019) Ali Shoeibi et al.   Frontiers in Neurology

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

(2019) Mike A Nalls et al.   LANCET NEUROLOGY

A multi-faceted genotoxic network of alpha-synuclein in the nucleus and mitochondria of dopaminergic neurons in Parkinson’s disease: Emerging concepts and challenges

(2019) Velmarini Vasquez et al.   PROGRESS IN NEUROBIOLOGY

Astroglial and microglial contributions to iron metabolism disturbance in Parkinson's disease

(2018) Ning Song et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Repetitive Mild Closed Head Injury Alters Protein Expression and Dendritic Complexity in a Mouse Model

(2018) Jessica N. Saykally et al.   JOURNAL OF NEUROTRAUMA

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

(2018) Rita Guerreiro et al.   LANCET NEUROLOGY

Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson’s disease

(2018) Emily M. Rocha et al.   NEUROBIOLOGY OF DISEASE

Distinct α-Synuclein strains and implications for heterogeneity among α-Synucleinopathies

(2018) Chao Peng et al.   NEUROBIOLOGY OF DISEASE

Difficulties in the diagnosis of four repeats (4R) tauopathic parkinsonian syndromes

(2018) Piotr Alster et al.   Neurologia i Neurochirurgia Polska

Mild TBI and risk of Parkinson disease

(2018) Raquel C. Gardner et al.   NEUROLOGY

[11C]PK11195 binding in Alzheimer disease and progressive supranuclear palsy

(2018) Luca Passamonti et al.   NEUROLOGY

Thalamic GABA levels and occupational manganese neurotoxicity: Association with exposure levels and brain MRI

(2018) Ruoyun E. Ma et al.   NEUROTOXICOLOGY

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

(2018) Marthe H. R. Ludtmann et al.   Nature Communications

Mechanisms of α-Synuclein Induced Synaptopathy in Parkinson's Disease

(2018) Jessika C. Bridi et al.   Frontiers in Neuroscience

Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease

(2018) Géraldine Gelders et al.   Journal of Immunology Research

Mitochondrial dysfunction in fibroblasts of Multiple System Atrophy

(2018) Giacomo Monzio Compagnoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Genetics of Dementia with Lewy Bodies: Current Understanding and Future Directions

(2018) Tatiana Orme et al.   Current Neurology and Neuroscience Reports

Cerebrospinal fluid concentrations of inflammatory markers in Parkinson’s disease and atypical parkinsonian disorders

(2018) Sara Hall et al.   Scientific Reports

Expression of α-synuclein is regulated in a neuronal cell type-dependent manner

(2018) Katsutoshi Taguchi et al.   ANATOMICAL SCIENCE INTERNATIONAL

Atypical parkinsonian syndromes: a general neurologist's perspective

(2017) A. B. Deutschländer et al.   EUROPEAN JOURNAL OF NEUROLOGY

Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson’s Disease

(2017) Velmarini Vasquez et al.   JOURNAL OF ALZHEIMERS DISEASE

Dementia with Lewy bodies and Parkinson’s disease-dementia: current concepts and controversies

(2017) Kurt A. Jellinger   JOURNAL OF NEURAL TRANSMISSION

Parkinson's Disease Is Not Simply a Prion Disorder

(2017) D. James Surmeier et al.   JOURNAL OF NEUROSCIENCE

Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain

(2017) Sneha Narasimhan et al.   JOURNAL OF NEUROSCIENCE

Viral-mediated oligodendroglial alpha-synuclein expression models multiple system atrophy

(2017) Fares Bassil et al.   MOVEMENT DISORDERS

Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria

(2017) Günter U. Höglinger et al.   MOVEMENT DISORDERS

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies

(2017) Celia Kun-Rodrigues et al.   NEUROBIOLOGY OF AGING

Vagotomy and Parkinson disease

(2017) Bojing Liu et al.   NEUROLOGY

Diagnosis and management of dementia with Lewy bodies

(2017) Ian G. McKeith et al.   NEUROLOGY

CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP

(2017) Julio C. Rojas et al.   NEUROLOGY

Blood-based NfL

(2017) Oskar Hansson et al.   NEUROLOGY

DCTN1 -related neurodegeneration: Perry syndrome and beyond

(2017) Takuya Konno et al.   PARKINSONISM & RELATED DISORDERS

Pathological α-synuclein exacerbates the progression of Parkinson’s disease through microglial activation

(2017) Qiu-Shuang Zhang et al.   TOXICOLOGY LETTERS

Rab GTPases in Immunity and Inflammation

(2017) Akriti Prashar et al.   Frontiers in Cellular and Infection Microbiology

Research Gaps and Controversies in Chronic Traumatic Encephalopathy

(2017) Breton M. Asken et al.   JAMA Neurology

GABA transmission via ATP-dependent K+channels regulates α-synuclein secretion in mouse striatum

(2016) Evangelia Emmanouilidou et al.   BRAIN

Imaging Systemic Dysfunction in Parkinson’s Disease

(2016) Per Borghammer et al.   Current Neurology and Neuroscience Reports

How strong is the evidence that Parkinsonʼs disease is a prion disorder?

(2016) Patrik Brundin et al.   CURRENT OPINION IN NEUROLOGY

Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource

(2016) Michael J. Keogh et al.   GENOME RESEARCH

C9orf72 Hexanucleotide Repeat Analysis in Cases with Pathologically Confirmed Dementia with Lewy Bodies

(2016) Joshua T. Geiger et al.   Neurodegenerative Diseases

A genome-wide association study in multiple system atrophy

(2016) Anna Sailer et al.   NEUROLOGY

α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease

(2016) Roberto Di Maio et al.   Science Translational Medicine

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

(2016) Martin Steger et al.   eLife

Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings

(2016) Paul K. Crane et al.   JAMA Neurology

Mössbauer Studies of Pathological Brain Tissues Affected by PSP Disease

(2016) J. Gałązka-Friedman et al.   ACTA PHYSICA POLONICA A

α-Synuclein is a Novel Microtubule Dynamase

(2016) Daniele Cartelli et al.   Scientific Reports

Vagotomy and subsequent risk of Parkinson's disease

(2015) Elisabeth Svensson et al.   ANNALS OF NEUROLOGY

Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies

(2015) Anne Stuendl et al.   BRAIN

Expanding the spectrum of neuronal pathology in multiple system atrophy

(2015) Matthew D. Cykowski et al.   BRAIN

Widespread microglial activation in patients deceased from traumatic brain injury

(2015) Antonio Velázquez et al.   BRAIN INJURY

Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease

(2015) Dominik Haddad et al.   FEBS LETTERS

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

MDS clinical diagnostic criteria for Parkinson's disease

(2015) Ronald B. Postuma et al.   MOVEMENT DISORDERS

Structure of the toxic core of α-synuclein from invisible crystals

(2015) Jose A. Rodriguez et al.   NATURE

Low levels of astroglial markers in Parkinson’s disease: relationship to α-synuclein accumulation

(2015) Junchao Tong et al.   NEUROBIOLOGY OF DISEASE

Multiple-System Atrophy

(2015) Alessandra Fanciulli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

(2015) Stanley B. Prusiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

(2015) Naomi Kouri et al.   Nature Communications

Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer’s disease or corticobasal degeneration brains

(2014) Susana Boluda et al.   ACTA NEUROPATHOLOGICA

Cutaneous neuropathy in Parkinson’s disease: a window into brain pathology

(2014) Kathrin Doppler et al.   ACTA NEUROPATHOLOGICA

Causes and Consequences of Degeneration of the Dorsal Motor Nucleus of the Vagus Nerve in Parkinson's Disease

(2014) James G. Greene   ANTIOXIDANTS & REDOX SIGNALING

Serum Urate and the Risk of Parkinson's Disease: Results From a Meta-Analysis

(2014) Chunhong Shen et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Alpha-synuclein mRNA expression in oligodendrocytes in MSA

(2014) Yasmine T. Asi et al.   GLIA

Divergent CSF   alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy

(2014) D. Wagshal et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Alpha-synuclein and tau: teammates in neurodegeneration?

(2014) Simon Moussaud et al.   Molecular Neurodegeneration

Neuropathology of multiple system atrophy: New thoughts about pathogenesis

(2014) Kurt A. Jellinger   MOVEMENT DISORDERS

Postganglionic sudomotor denervation in patients with multiple system atrophy

(2014) V. Provitera et al.   NEUROLOGY

Skin nerve  -synuclein deposits: A biomarker for idiopathic Parkinson disease

(2014) V. Donadio et al.   NEUROLOGY

Peripheral nervous system involvement in Parkinson's disease: Evidence and controversies

(2014) C. Comi et al.   PARKINSONISM & RELATED DISORDERS

α-Synuclein inclusions in the skin of Parkinson's disease and parkinsonism

(2014) Ildefonso Rodríguez-Leyva et al.   Annals of Clinical and Translational Neurology

Characterization of tau oligomeric seeds in progressive supranuclear palsy

(2014) Julia E Gerson et al.   Acta Neuropathologica Communications

Pro-inflammatory cytokines modulate iron regulatory protein 1 expression and iron transportation through reactive oxygen/nitrogen species production in ventral mesencephalic neurons

(2013) Jia Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

March separate, strike together — Role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease

(2013) Anne Eckert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Prion-like spreading of pathological α-synuclein in brain

(2013) Masami Masuda-Suzukake et al.   BRAIN

Overview and Findings from the Religious Orders Study

(2013) David A. Bennett et al.   Current Alzheimer Research

Overview and Findings from the Rush Memory and Aging Project

(2013) David A. Bennett et al.   Current Alzheimer Research

Manganese neurotoxicity and the role of reactive oxygen species

(2013) Ebany J. Martinez-Finley et al.   FREE RADICAL BIOLOGY AND MEDICINE

Parkinson Disease Affects Peripheral Sensory Nerves in the Pharynx

(2013) Liancai Mu et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Alpha-Synuclein Pathology and Axonal Degeneration of the Peripheral Motor Nerves Innervating Pharyngeal Muscles in Parkinson Disease

(2013) Liancai Mu et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy

(2013) Victoria S Burchell et al.   NATURE NEUROSCIENCE

 -Synuclein in cutaneous autonomic nerves

(2013) N. Wang et al.   NEUROLOGY

Criteria for the diagnosis of corticobasal degeneration

(2013) M. J. Armstrong et al.   NEUROLOGY

Mutations in COQ2 in Familial and Sporadic Multiple-System Atrophy

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Transmission of multiple system atrophy prions to transgenic mice

(2013) J. C. Watts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model

(2013) S. Janezic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Large  -synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking

(2013) B.-K. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parkinson's Disease and Parkinsonism: Neuropathology

(2013) D. W. Dickson   Cold Spring Harbor Perspectives in Medicine

Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes

(2013) Lilach Soreq et al.   Frontiers in Molecular Neuroscience

Formation and Propagation of Tau Oligomeric Seeds

(2013) Julia E. Gerson et al.   Frontiers in Neurology

Role of Oxidative Stress in Parkinson's Disease

(2013) Onyou Hwang   Experimental Neurobiology

α-Synuclein oligomers and clinical implications for Parkinson disease

(2012) Lorraine V. Kalia et al.   ANNALS OF NEUROLOGY

Mitophagy: mechanisms, pathophysiological roles, and analysis

(2012) Wen-Xing Ding et al.   BIOLOGICAL CHEMISTRY

PINK1 stimulates interleukin-1β-mediated inflammatory signaling via the positive regulation of TRAF6 and TAK1

(2012) Hyun Jung Lee et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Effect of ferroportin polymorphism on iron homeostasis and infection

(2012) Ishmael Kasvosve   CLINICA CHIMICA ACTA

Inflammatory cytokines and NT-proCNP in Parkinson’s disease patients

(2012) Dariusz Koziorowski et al.   CYTOKINE

Phosphorylated α-synuclein as a potential biomarker for Parkinson’s disease and related disorders

(2012) Penelope Foulds et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Classic and New Animal Models of Parkinson's Disease

(2012) Javier Blesa et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Psychosis,C9ORF72and dementia with Lewy bodies: Table 1

(2012) Julie S Snowden et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Autopsy confirmed multiple system atrophy cases: Mayo experience and role of autonomic function tests

(2012) Valeria Iodice et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

A New Link to Mitochondrial Impairment in Tauopathies

(2012) Kathrin L. Schulz et al.   MOLECULAR NEUROBIOLOGY

Alpha-synuclein and Protein Degradation Systems: a Reciprocal Relationship

(2012) Maria Xilouri et al.   MOLECULAR NEUROBIOLOGY

Neuropathology and pathophysiology of multiple system atrophy

(2012) K. A. Jellinger   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

High hepcidin level accounts for the nigral iron accumulation in acute peripheral iron intoxication rats

(2012) Chao Sun et al.   TOXICOLOGY LETTERS

Transmission of Synucleinopathies in the Enteric Nervous System of A53T Alpha-Synuclein Transgenic Mice

(2012) He-Jin Lee et al.   Experimental Neurobiology

A proteomic study identifies different levels of light chain ferritin in corticobasal degeneration and progressive supranuclear palsy

(2011) Abdul Shukkur Ebrahim et al.   ACTA NEUROPATHOLOGICA

Widespread Tau and Amyloid-Beta Pathology Many Years After a Single Traumatic Brain Injury in Humans

(2011) Victoria E. Johnson et al.   BRAIN PATHOLOGY

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

(2011) Xinnan Wang et al.   CELL

Genome-wide association study confirms extant PD risk loci among the Dutch

(2011) Javier Simón-Sánchez et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Disruption of astrocytic glutamine turnover by manganese is mediated by the protein kinase C pathway

(2011) Marta Sidoryk-Wegrzynowicz et al.   GLIA

Hepcidin directly inhibits transferrin receptor 1 expression in astrocytes via a cyclic AMP-protein kinase a pathway

(2011) Fang Du et al.   GLIA

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

(2011)   LANCET

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

(2011) Günter U Höglinger et al.   NATURE GENETICS

Corticobasal degeneration: a pathologically distinct 4R tauopathy

(2011) Naomi Kouri et al.   Nature Reviews Neurology

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission

(2011) Lydia Alvarez-Erviti et al.   NEUROBIOLOGY OF DISEASE

Pathological correlates of gastrointestinal dysfunction in Parkinson's disease

(2011) Maria G. Cersosimo et al.   NEUROBIOLOGY OF DISEASE

A progranulin mutation associated with cortico-basal syndrome in an Italian family expressing different phenotypes of fronto-temporal lobar degeneration

(2011) Cinzia Coppola et al.   NEUROLOGICAL SCIENCES

MAPT H1 haplotype is a risk factor for essential tremor and multiple system atrophy

(2011) C. Vilarino-Guell et al.   NEUROLOGY

Cytokine expression and microglial activation in progressive supranuclear palsy

(2011) Rafael Fernández-Botrán et al.   PARKINSONISM & RELATED DISORDERS

Are dysautonomic and sensory symptoms present in early Parkinson’s disease?

(2010) O.-B. Tysnes et al.   ACTA NEUROLOGICA SCANDINAVICA

Papp–Lantos inclusions and the pathogenesis of multiple system atrophy: an update

(2010) Kurt A. Jellinger et al.   ACTA NEUROPATHOLOGICA

Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders

(2010) Thomas G. Beach et al.   ACTA NEUROPATHOLOGICA

The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia

(2010) Walter J. Schulz-Schaeffer   ACTA NEUROPATHOLOGICA

Hepcidin and Disorders of Iron Metabolism

(2010) Tomas Ganz et al.   Annual Review of Medicine

SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s disease

(2010) Pablo Garcia-Reitböck et al.   BRAIN

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1

(2010) Frits Kamp et al.   EMBO JOURNAL

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

(2010) I. Irrcher et al.   HUMAN MOLECULAR GENETICS

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

Over-expression of alpha-synuclein in the nervous system enhances axonal degeneration after peripheral nerve lesion in a transgenic mouse strain

(2010) Heike Siebert et al.   JOURNAL OF NEUROCHEMISTRY

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

(2010) Taye H Hamza et al.   NATURE GENETICS

Iron and reactive oxygen species activity in parkinsonian substantia nigra

(2010) Anna Wypijewska et al.   PARKINSONISM & RELATED DISORDERS

The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway

(2010) Angela C. Poole et al.   PLoS One

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

Circulating interleukin-10 and interleukin-12 in Parkinson’s disease

(2009) M. Rentzos et al.   ACTA NEUROLOGICA SCANDINAVICA

SNCAvariants are associated with increased risk for multiple system atrophy

(2009) Sonja W. Scholz et al.   ANNALS OF NEUROLOGY

α-Synuclein contributes to GSK-3β-catalyzed Tau phosphorylation in Parkinson’s disease models

(2009) Tetyana Duka et al.   FASEB JOURNAL

Ferroportin 1 but not hephaestin contributes to iron accumulation in a cell model of Parkinson's disease

(2009) Ning Song et al.   FREE RADICAL BIOLOGY AND MEDICINE

Degeneration in Different Parkinsonian Syndromes Relates to Astrocyte Type and Astrocyte Protein Expression

(2009) Yun Ju C. Song et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Molecular interaction of α-synuclein with tubulin influences on the polymerization of microtubule in vitro and structure of microtubule in cells

(2009) R. M. Zhou et al.   MOLECULAR BIOLOGY REPORTS

Serum levels of interleukin-6 are elevated in patients with Parkinson's disease and correlate with physical performance

(2009) Paula Scalzo et al.   NEUROSCIENCE LETTERS

Loss of A5 noradrenergic neurons in multiple system atrophy

(2008) Eduardo E. Benarroch et al.   ACTA NEUROPATHOLOGICA

Iron-enhanced paraquat-mediated dopaminergic cell death due to increased oxidative stress as a consequence of microglial activation

(2008) Jun Peng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Second consensus statement on the diagnosis of multiple system atrophy

(2008) S. Gilman et al.   NEUROLOGY

Serum interleukin (IL-2, IL-10, IL-6, IL-4), TNFα, and INFγ concentrations are elevated in patients with atypical and idiopathic parkinsonism

(2008) Bogdan Brodacki et al.   NEUROSCIENCE LETTERS

A Parkinsonian Syndrome in Methcathinone Users and the Role of Manganese

(2008) Ainārs Stepens et al.   NEW ENGLAND JOURNAL OF MEDICINE

Serum inflammatory biomarkers in Parkinson's disease

(2008) M. Dufek et al.   PARKINSONISM & RELATED DISORDERS

Axonal  -synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease

(2007) S. Orimo et al.   BRAIN