- Home
- Publications
- Publication Search
- Publication Details
Title
Interleukin-17A: The Key Cytokine in Neurodegenerative Diseases
Authors
Keywords
-
Journal
Frontiers in Aging Neuroscience
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-09-29
DOI
10.3389/fnagi.2020.566922
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Peripheral adaptive immunity of the triple transgenic mouse model of Alzheimer’s disease
- (2019) Isabelle St-Amour et al. Journal of Neuroinflammation
- Altered human oligodendrocyte heterogeneity in multiple sclerosis
- (2019) Sarah Jäkel et al. NATURE
- The IL-17 Family of Cytokines in Health and Disease
- (2019) Mandy J. McGeachy et al. IMMUNITY
- Immune Signaling in Neurodegeneration
- (2019) Timothy R. Hammond et al. IMMUNITY
- IL-17A exacerbates neuroinflammation and neurodegeneration by activating microglia in rodent models of Parkinson's disease
- (2019) Zhan Liu et al. BRAIN BEHAVIOR AND IMMUNITY
- Th17 cells in glaucoma patients promote Ig production in IL‐17A and IL‐21‐dependent manner
- (2019) Yongbo Ren et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- The Alzheimer’s Disease–Associated Protein BACE1 Modulates T Cell Activation and Th17 Function
- (2019) Gerard Hernandez-Mir et al. JOURNAL OF IMMUNOLOGY
- Oxymatrine can attenuate pathological deficits of Alzheimer's disease mice through regulation of neuroinflammation
- (2019) Yun Chen et al. JOURNAL OF NEUROIMMUNOLOGY
- RANTES-induced invasion of Th17 cells into substantia nigra potentiates dopaminergic cell loss in MPTP mouse model of Parkinson's disease
- (2019) Debashis Dutta et al. NEUROBIOLOGY OF DISEASE
- A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System
- (2018) Yan Qin et al. CELL
- TREM2 inhibits inflammatory responses in mouse microglia by suppressing the PI3K/NF-κB signaling
- (2018) Caixia Li et al. CELL BIOLOGY INTERNATIONAL
- Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson’s Disease
- (2018) Annika Sommer et al. Cell Stem Cell
- Neuroimmflammation and microglia in glaucoma: time for a paradigm shift
- (2018) Xin Wei et al. JOURNAL OF NEUROSCIENCE RESEARCH
- γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis
- (2018) Ayano C. Kohlgruber et al. NATURE IMMUNOLOGY
- Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy
- (2018) Krista J. Spiller et al. NATURE NEUROSCIENCE
- A stocked toolbox for understanding the role of astrocytes in disease
- (2018) Akshata Almad et al. Nature Reviews Neurology
- Organ-specific mechanisms linking innate and adaptive antifungal immunity
- (2018) Rebecca A. Drummond et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes
- (2018) Sara E. Nasrabady et al. Acta Neuropathologica Communications
- Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
- (2018) Tyler J. Bussian et al. NATURE
- Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model
- (2018) Giuseppe Locatelli et al. NATURE NEUROSCIENCE
- Focus on neurodegenerative disease
- (2018) NATURE NEUROSCIENCE
- Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia
- (2018) Jack Brelstaff et al. Cell Reports
- MiR-409-3p and MiR-1896 co-operatively participate in IL-17-induced inflammatory cytokine production in astrocytes and pathogenesis of EAE mice via targeting SOCS3/STAT3 signaling
- (2018) Xiaomei Liu et al. GLIA
- Reduced Annexin A1 Secretion by ABCA1 Causes Retinal Inflammation and Ganglion Cell Apoptosis in a Murine Glaucoma Model
- (2018) Lu Li et al. Frontiers in Cellular Neuroscience
- Neuroprotection for glaucoma: Requirements for clinical translation
- (2017) Leonard A. Levin et al. EXPERIMENTAL EYE RESEARCH
- Impaired IL-17 Production in Gut-Residing Immune Cells of 5xFAD Mice with Alzheimer’s Disease Pathology
- (2017) Tamara Saksida et al. JOURNAL OF ALZHEIMERS DISEASE
- Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation
- (2017) Tao Peng et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Tenascin-C deficiency protects mice from experimental autoimmune encephalomyelitis
- (2017) Miljana Momčilović et al. JOURNAL OF NEUROIMMUNOLOGY
- Immunological alteration & toxic molecular inductions leading to cognitive impairment & neurotoxicity in transgenic mouse model of Alzheimer's disease
- (2017) Manuj Ahuja et al. LIFE SCIENCES
- The Role of IL-17 and Related Cytokines in Inflammatory Autoimmune Diseases
- (2017) Taku Kuwabara et al. MEDIATORS OF INFLAMMATION
- IL-17B: A new area of study in the IL-17 family
- (2017) Qingli Bie et al. MOLECULAR IMMUNOLOGY
- Reduced Activated T Lymphocytes (CD4+CD25+) and Plasma Levels of Cytokines in Parkinson’s Disease
- (2017) Natalia Pessoa Rocha et al. MOLECULAR NEUROBIOLOGY
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Amyotrophic Lateral Sclerosis
- (2017) Robert H. Brown et al. NEW ENGLAND JOURNAL OF MEDICINE
- Neuroprotective effects of ellagic acid on cuprizone-induced acute demyelination through limitation of microgliosis, adjustment of CXCL12/IL-17/IL-11 axis and restriction of mature oligodendrocytes apoptosis
- (2017) Nima Sanadgol et al. PHARMACEUTICAL BIOLOGY
- The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway
- (2017) Emilie Laprevotte et al. Oncotarget
- IL-17B activated mesenchymal stem cells enhance proliferation and migration of gastric cancer cells
- (2017) Qingli Bie et al. Oncotarget
- IL-17 signalling in astrocytes promotes glutamate excitotoxicity: Indications for the link between inflammatory and neurodegenerative events in multiple sclerosis
- (2017) Milos Kostic et al. Multiple Sclerosis and Related Disorders
- Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease
- (2017) Athanassios Fragoulis et al. Redox Biology
- Reactive gliosis in the pathogenesis of CNS diseases
- (2016) Milos Pekny et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- IL-17A and Multiple Sclerosis: Signaling Pathways, Producing Cells and Target Cells in the Central Nervous System
- (2016) Frank Kolbinger et al. CURRENT DRUG TARGETS
- An evolving view of transition zone and midmantle viscosity
- (2016) Scott D. King GEOCHEMISTRY GEOPHYSICS GEOSYSTEMS
- Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation
- (2016) Pawan Kumar et al. IMMUNITY
- Interleukin-17A neutralization alleviated ocular neovascularization by promoting M2 and mitigating M1 macrophage polarization
- (2016) Yanji Zhu et al. IMMUNOLOGY
- Th17 Cells Induce Dopaminergic Neuronal Death via LFA-1/ICAM-1 Interaction in a Mouse Model of Parkinson’s Disease
- (2016) Zhan Liu et al. MOLECULAR NEUROBIOLOGY
- Motor symptoms in Parkinson’s disease: A unified framework
- (2016) Ahmed A. Moustafa et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- How neuroinflammation contributes to neurodegeneration
- (2016) R. M. Ransohoff SCIENCE
- Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance
- (2016) Robert Saddawi-Konefka et al. Cell Reports
- The role of IL-17 in CNS diseases
- (2015) Ari Waisman et al. ACTA NEUROPATHOLOGICA
- Matrine improves cognitive impairment and modulates the balance of Th17/Treg cytokines in a rat model of A β1-42 -induced Alzheimer’s disease
- (2015) Yanfeng Zhang et al. Central European Journal of Immunology
- Astrocyte development: A Guide for the Perplexed
- (2015) Anna Victoria Molofsky et al. GLIA
- Interleukin-17B Antagonizes Interleukin-25-Mediated Mucosal Inflammation
- (2015) Joseph M. Reynolds et al. IMMUNITY
- IL-17–Mediated Immunity to the Opportunistic Fungal PathogenCandida albicans
- (2015) Heather R. Conti et al. JOURNAL OF IMMUNOLOGY
- Preferential Recruitment of Neutrophils into the Cerebellum and Brainstem Contributes to the Atypical Experimental Autoimmune Encephalomyelitis Phenotype
- (2015) Yudong Liu et al. JOURNAL OF IMMUNOLOGY
- Tripchlorolide ameliorates experimental autoimmune encephalomyelitis by down-regulating ERK1/2-NF-κB and JAK/STAT signaling pathways
- (2015) Jian Zhang et al. JOURNAL OF NEUROCHEMISTRY
- IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation
- (2015) Jie Sun et al. Journal of Neuroinflammation
- A Study to Evaluate the Safety, Tolerability, and Efficacy of Brodalumab in Subjects with Rheumatoid Arthritis and an Inadequate Response to Methotrexate
- (2015) K. Pavelka et al. JOURNAL OF RHEUMATOLOGY
- Commensal–dendritic-cell interaction specifies a unique protective skin immune signature
- (2015) Shruti Naik et al. NATURE
- Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis
- (2015) Marianna Marino et al. NEUROBIOLOGY OF AGING
- All-trans-Retinoic Acid Modulates Nitric Oxide and Interleukin-17A Production by Peripheral Blood Mononuclear Cells from Patients with Alzheimer's Disease
- (2015) Nassima Behairi et al. NEUROIMMUNOMODULATION
- Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis
- (2015) Dominique Baeten et al. NEW ENGLAND JOURNAL OF MEDICINE
- Control of IL-17 receptor signaling and tissue inflammation by the p38α–MKP-1 signaling axis in a mouse model of multiple sclerosis
- (2015) Gonghua Huang et al. Science Signaling
- Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model
- (2015) Seung-Hoon Yang et al. Scientific Reports
- Control of IL-17 receptor signaling and tissue inflammation by the p38α–MKP-1 signaling axis in a mouse model of multiple sclerosis
- (2015) Gonghua Huang et al. Science Signaling
- Protection of TGF-β1 against Neuroinflammation and Neurodegeneration in Aβ1–42-Induced Alzheimer’s Disease Model Rats
- (2015) Jia-Hui Chen et al. PLoS One
- Fingolimod may support neuroprotection via blockade of astrocyte nitric oxide
- (2014) Emanuela Colombo et al. ANNALS OF NEUROLOGY
- Toll-like receptor signaling directly increases functional IL-17RA expression in neuroglial cells
- (2014) Guoping Liu et al. CLINICAL IMMUNOLOGY
- Increased Serum Levels of Interleukin-18, -23 and -17 in Chinese Patients with Alzheimer's Disease
- (2014) Jin-Mei Chen et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- IL-17A activates ERK1/2 and enhances differentiation of oligodendrocyte progenitor cells
- (2014) Jane M. Rodgers et al. GLIA
- Interleukin-17 (IL-17)-induced MicroRNA 873 (miR-873) Contributes to the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting A20 Ubiquitin-editing Enzyme
- (2014) Xiaomei Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IL-17A Induces MIP-1α Expression in Primary Astrocytes via Src/MAPK/PI3K/NF-kB Pathways: Implications for Multiple Sclerosis
- (2014) Hongwei Yi et al. Journal of Neuroimmune Pharmacology
- T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases
- (2014) Hugo González et al. Journal of Neuroinflammation
- Erythropoietin modulates the immune-inflammatory response of a SOD1G93A transgenic mouse model of amyotrophic lateral sclerosis (ALS)
- (2014) Min Young Noh et al. NEUROSCIENCE LETTERS
- IL-17 and Glutamate Excitotoxicity in the Pathogenesis of Multiple Sclerosis
- (2014) M. Kostic et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Inhibitory effect of IL-17 on neural stem cell proliferation and neural cell differentiation
- (2013) Zichen Li et al. BMC IMMUNOLOGY
- Neuroprotection effect of interleukin (IL)-17 secreted by reactive astrocytes is emerged from a high-level IL-17-containing environment during acute neuroinflammation
- (2013) M. H. Hu et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- From Mechanosensitivity to Inflammatory Responses: New Players in the Pathology of Glaucoma
- (2013) David Križaj et al. CURRENT EYE RESEARCH
- IL-17 inhibits adipogenesis in part via C/EBPα, PPARγ and Krüppel-like factors
- (2013) Mushtaq Ahmed et al. CYTOKINE
- IL-17 family: Cytokines, receptors and signaling
- (2013) Chunfang Gu et al. CYTOKINE
- IL-17 targeted therapies for psoriasis
- (2013) Andrea Chiricozzi et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- IFN- Production by Amyloid -Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer's Disease
- (2013) T. C. Browne et al. JOURNAL OF IMMUNOLOGY
- Act1 mediates IL-17–induced EAE pathogenesis selectively in NG2+ glial cells
- (2013) Zizhen Kang et al. NATURE NEUROSCIENCE
- Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
- (2013) Shin H Kang et al. NATURE NEUROSCIENCE
- Respiratory infection promotes T cell infiltration and amyloid-β deposition in APP/PS1 mice
- (2013) Róisín M. McManus et al. NEUROBIOLOGY OF AGING
- Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP
- (2013) W. T. Hu et al. NEUROLOGY
- A Formalized Design Process for Bacterial Consortia That Perform Logic Computing
- (2013) Weiyue Ji et al. PLoS One
- CNS-Targeted Production of IL-17A Induces Glial Activation, Microvascular Pathology and Enhances the Neuroinflammatory Response to Systemic Endotoxemia
- (2013) Julian Zimmermann et al. PLoS One
- Does autoimmunity play a part in the pathogenesis of glaucoma?
- (2013) Katharina Bell et al. PROGRESS IN RETINAL AND EYE RESEARCH
- The Deubiquitinase A20 Mediates Feedback Inhibition of Interleukin-17 Receptor Signaling
- (2013) A. V. Garg et al. Science Signaling
- National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
- (2012) Bradley T. Hyman et al. Alzheimers & Dementia
- Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease
- (2012) James D. Doecke ARCHIVES OF NEUROLOGY
- Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression of T cell-mediated neuronal inflammation in mice
- (2012) Jun Wang et al. EXPERIMENTAL NEUROLOGY
- The Antimicrobial Protein REG3A Regulates Keratinocyte Proliferation and Differentiation after Skin Injury
- (2012) Yuping Lai et al. IMMUNITY
- Neuronal IL-17 receptor upregulates TRPV4 but not TRPV1 receptors in DRG neurons and mediates mechanical but not thermal hyperalgesia
- (2012) Gisela Segond von Banchet et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- CNS-specific Therapy for Ongoing EAE by Silencing IL-17 Pathway in Astrocytes
- (2012) Yaping Yan et al. MOLECULAR THERAPY
- Matrine Suppresses Production of IL-23/IL-17 and Ameliorates Experimental Autoimmune Encephalomyelitis
- (2011) Xiaoyu Zhao et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Recent advances in the IL-17 cytokine family
- (2011) Sarah L Gaffen CURRENT OPINION IN IMMUNOLOGY
- Life before Seventeen: Cloning of the IL-17 Receptor
- (2011) S. L. Gaffen JOURNAL OF IMMUNOLOGY
- IL-17C regulates the innate immune function of epithelial cells in an autocrine manner
- (2011) Vladimir Ramirez-Carrozzi et al. NATURE IMMUNOLOGY
- Chronic Mucocutaneous Candidiasis in Humans With Inborn Errors of Interleukin-17 Immunity
- (2011) Douglas F. McMahon et al. PEDIATRICS
- A CC' Loop Decoy Peptide Blocks the Interaction Between Act1 and IL-17RA to Attenuate IL-17- and IL-25-Induced Inflammation
- (2011) C. Liu et al. Science Signaling
- Alzheimer's Disease: The Challenge of the Second Century
- (2011) D. M. Holtzman et al. Science Translational Medicine
- Interleukin-17 and interleukin-23 are elevated in serum and cerebrospinal fluid of patients with ALS: a reflection of Th17 cells activation?
- (2010) M. Rentzos et al. ACTA NEUROLOGICA SCANDINAVICA
- Clinical progression in Parkinson disease and the neurobiology of axons
- (2010) Hsiao-Chun Cheng et al. ANNALS OF NEUROLOGY
- Increased activity of Th-17 and Th-9 lymphocytes and a skewing of the post-thymic differentiation pathway are seen in Alzheimer’s disease
- (2010) Marina Saresella et al. BRAIN BEHAVIOR AND IMMUNITY
- A biomechanical paradigm for axonal insult within the optic nerve head in aging and glaucoma
- (2010) Claude F. Burgoyne EXPERIMENTAL EYE RESEARCH
- Astrocyte-Restricted Ablation of Interleukin-17-Induced Act1-Mediated Signaling Ameliorates Autoimmune Encephalomyelitis
- (2010) Zizhen Kang et al. IMMUNITY
- Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease
- (2010) Reiko M. Onishi et al. IMMUNOLOGY
- Induction of Neutrophil Gelatinase-associated Lipocalin Expression by Co-stimulation with Interleukin-17 and Tumor Necrosis Factor-α Is Controlled by IκB-ζ but neither by C/EBP-β nor C/EBP-δ
- (2010) Joachim R. Karlsen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IL-17RC Is Required for IL-17A- and IL-17F-Dependent Signaling and the Pathogenesis of Experimental Autoimmune Encephalomyelitis
- (2010) Y. Hu et al. JOURNAL OF IMMUNOLOGY
- Synergistic activity of interleukin-17 and tumor necrosis factor-α enhances oxidative stress-mediated oligodendrocyte apoptosis
- (2010) Manjeet K. Paintlia et al. JOURNAL OF NEUROCHEMISTRY
- IL-17A is increased in the serum and in spinal cord CD8 and mast cells of ALS patients
- (2010) Milan Fiala et al. Journal of Neuroinflammation
- Novel CSF biomarkers for frontotemporal lobar degenerations
- (2010) W. T. Hu et al. NEUROLOGY
- Evolving expectations around early management of multiple sclerosis
- (2010) Ralf Gold et al. Therapeutic Advances in Neurological Disorders
- Oligodendrocytes: biology and pathology
- (2009) Monika Bradl et al. ACTA NEUROPATHOLOGICA
- Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
- (2009) Ivaylo I. Ivanov et al. CELL
- HLA-DR Alleles in Amyloid -Peptide Autoimmunity: A Highly Immunogenic Role for the DRB1*1501 Allele
- (2009) V. Zota et al. JOURNAL OF IMMUNOLOGY
- Functional interleukin-17 receptor A is expressed in central nervous system glia and upregulated in experimental autoimmune encephalomyelitis
- (2009) Jayasri Sarma et al. Journal of Neuroinflammation
- Structural basis of receptor sharing by interleukin 17 cytokines
- (2009) Lauren K Ely et al. NATURE IMMUNOLOGY
- Production and functions of IL-17 in microglia
- (2008) Jun Kawanokuchi et al. JOURNAL OF NEUROIMMUNOLOGY
- Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
- (2008) Jing-Ji Jin et al. Journal of Neuroinflammation
- Induced Autoimmunity to Heat Shock Proteins Elicits Glaucomatous Loss of Retinal Ganglion Cell Neurons via Activated T-Cell-Derived Fas-Ligand
- (2008) M. B. Wax et al. JOURNAL OF NEUROSCIENCE
- Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis
- (2008) Ying Wang et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells
- (2008) Ingunn M Stromnes et al. NATURE MEDICINE
- Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis
- (2007) John S. Tzartos et al. AMERICAN JOURNAL OF PATHOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation