A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms
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Title
A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate
Pseudomonas aeruginosa
Biofilms
Authors
Keywords
-
Journal
Advanced Science
Volume -, Issue -, Pages 2004369
Publisher
Wiley
Online
2021-03-19
DOI
10.1002/advs.202004369
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Note: Only part of the references are listed.- Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections
- (2020) Duy‐Khiet Ho et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa
- (2020) Fadi Soukarieh et al. Frontiers in Chemistry
- Preclinical Development of Orally Inhaled Drugs (OIDs)—Are Animal Models Predictive or Shall We Move Towards In Vitro Non-Animal Models?
- (2020) Dania Movia et al. Animals
- Micro-rheological properties of lung homogenates correlate with infection severity in a mouse model of Pseudomonas aeruginosa lung infection
- (2020) Xabier Murgia et al. Scientific Reports
- Evaluation of 1,2,3-Triazoles as Amide Bioisosteres In Cystic Fibrosis Transmembrane Conductance Regulator Modulators VX-770 and VX-809
- (2019) Jake E. Doiron et al. CHEMISTRY-A EUROPEAN JOURNAL
- Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface
- (2019) Sankalp Malhotra et al. CLINICAL MICROBIOLOGY REVIEWS
- Flexible Fragment Growing Boosts Potency of Quorum‐Sensing Inhibitors against Pseudomonas aeruginosa Virulence
- (2019) Michael Zender et al. ChemMedChem
- Challenges and strategies in drug delivery systems for treatment of pulmonary infections
- (2019) Duy-Khiet Ho et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Antibiotic efficacy varies based on the infection model and treatment regimen for Pseudomonas aeruginosa
- (2019) Cristina Cigana et al. EUROPEAN RESPIRATORY JOURNAL
- The challenge of converting Gram-positive-only compounds into broad-spectrum antibiotics
- (2018) Michelle F. Richter et al. Annals of the New York Academy of Sciences
- Pseudomonas aeruginosatranscriptome during human infection
- (2018) Daniel M. Cornforth et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting the Pseudomonas quinolone signal quorum sensing system for the discovery of novel anti-infective pathoblockers
- (2018) Christian Schütz et al. Beilstein Journal of Organic Chemistry
- Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: A longitudinal study
- (2017) Helen L. Barr et al. Journal of Cystic Fibrosis
- Predictive compound accumulation rules yield a broad-spectrum antibiotic
- (2017) Michelle F. Richter et al. NATURE
- Structure–functionality relationship and pharmacological profiles of Pseudomonas aeruginosa alkylquinolone quorum sensing modulators
- (2017) Ahmed A. M. Kamal et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Bezlotoxumab: A Novel Agent for the Prevention of Recurrent Clostridium difficile Infection
- (2017) Wesley D. Kufel et al. PHARMACOTHERAPY
- Application of Dual Inhibition Concept within Looped Autoregulatory Systems toward Antivirulence Agents against Pseudomonas aeruginosa Infections
- (2016) Andreas Thomann et al. ACS Chemical Biology
- Biofilm Antimicrobial Susceptibility Increases With Antimicrobial Exposure Time
- (2016) Paulo Castaneda et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
- The Approach to Pseudomonas aeruginosa in Cystic Fibrosis
- (2016) Jaideep S. Talwalkar et al. CLINICS IN CHEST MEDICINE
- Insights into host-pathogen interactions from state-of-the-art animal models of respiratoryPseudomonas aeruginosainfections
- (2016) Anne Lorenz et al. FEBS LETTERS
- Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections
- (2016) Stefanie Wagner et al. JOURNAL OF MEDICINAL CHEMISTRY
- Therapeutic challenges posed by critical drug-drug interactions in cystic fibrosis
- (2016) Cameron L. Jordan et al. PEDIATRIC PULMONOLOGY
- Unravelling the Genome-Wide Contributions of Specific 2-Alkyl-4-Quinolones and PqsE to Quorum Sensing in Pseudomonas aeruginosa
- (2016) Giordano Rampioni et al. PLoS Pathogens
- An analysis of the attrition of drug candidates from four major pharmaceutical companies
- (2015) Michael J. Waring et al. NATURE REVIEWS DRUG DISCOVERY
- Identification of Anti-virulence Compounds That Disrupt Quorum-Sensing Regulated Acute and Persistent Pathogenicity
- (2014) Melissa Starkey et al. PLoS Pathogens
- Extracellular DNA Shields against Aminoglycosides in Pseudomonas aeruginosa Biofilms
- (2013) Wen-Chi Chiang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Platforms for antibiotic discovery
- (2013) Kim Lewis NATURE REVIEWS DRUG DISCOVERY
- Braces for the Peptide Backbone: Insights into Structure-Activity Relationships of Protease Inhibitor Mimics with Locked Amide Conformations
- (2012) Marco Tischler et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Pseudomonas aeruginosa: all roads lead to resistance
- (2011) Elena B.M. Breidenstein et al. TRENDS IN MICROBIOLOGY
- Murine models of acute and chronic lung infection with cystic fibrosis pathogens
- (2010) Alessandra Bragonzi INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- Anti-virulence strategies to combat bacteria-mediated disease
- (2010) David A. Rasko et al. NATURE REVIEWS DRUG DISCOVERY
- Pseudomonas aeruginosa – a phenomenon of bacterial resistance
- (2009) Tanya Strateva et al. JOURNAL OF MEDICAL MICROBIOLOGY
- Synthesis and Antibiofilm Activity of a Second-Generation Reverse-Amide Oroidin Library: A Structure-Activity Relationship Study
- (2008) T. Eric Ballard et al. CHEMISTRY-A EUROPEAN JOURNAL
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