Two novel loci underlie natural differences in Caenorhabditis elegans abamectin responses

Natural variation in a glucuronosyltransferase modulates propionate sensitivity in a C. elegans propionic acidemia model

(2020) Huimin Na et al.   PLoS Genetics

Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus

(2019) Stephen R. Doyle et al.   BMC GENOMICS

A Novel Gene Underlies Bleomycin-Response Variation in Caenorhabditis elegans

(2019) Shannon C. Brady et al.   GENETICS

Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk

(2019) Alejandro Burga et al.   Nature Communications

Deep sampling of Hawaiian Caenorhabditis elegans reveals high genetic diversity and admixture with global populations

(2019) Tim A Crombie et al.   eLife

Similarities and differences in the biotransformation and transcriptomic responses of Caenorhabditis elegans and Haemonchus contortus to five different benzimidazole drugs

(2019) S.J. Stasiuk et al.   International Journal for Parasitology-Drugs and Drug Resistance

Discovery of genomic intervals that underlie nematode responses to benzimidazoles

(2018) Mostafa Zamanian et al.   PLoS Neglected Tropical Diseases

MIPhy: identify and quantify rapidly evolving members of large gene families

(2018) David M. Curran et al.   PeerJ

The sensory amphidial structures of Caenorhabditis elegans are involved in macrocyclic lactone uptake and anthelmintic resistance

(2018) Antony P. Page   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Genetic Markers of Benzimidazole Resistance among Human Hookworms (Necator americanus) in Kintampo North Municipality, Ghana

(2018) Ambrose R. Orr et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resistance to benzimidazoles

(2018) Steffen R. Hahnel et al.   PLoS Pathogens

WormBase ParaSite − a comprehensive resource for helminth genomics

(2017) Kevin L. Howe et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Genomic introgression mapping of field-derived multiple-anthelmintic resistance in Teladorsagia circumcincta

(2017) Young-Jun Choi et al.   PLoS Genetics

Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons

(2017) Stefan Zdraljevic et al.   PLoS Genetics

Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity

(2017) Stephen R. Doyle et al.   PLoS Neglected Tropical Diseases

Prospects and challenges of CRISPR/Cas genome editing for the study and control of neglected vector-borne nematode diseases

(2016) Mostafa Zamanian et al.   FEBS Journal

Evidence from two independent backcross experiments supports genetic linkage of microsatellite Hcms8a20, but not other candidate loci, to a major ivermectin resistance locus in Haemonchus contortus

(2016) Andrew M. Rezansoff et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Molecular mechanisms for anthelmintic resistance in strongyle nematode parasites of veterinary importance

(2016) J. H. Whittaker et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

The Role of Xenobiotic-Metabolizing Enzymes in Anthelmintic Deactivation and Resistance in Helminths

(2016) Petra Matoušková et al.   TRENDS IN PARASITOLOGY

A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains

(2015) Erik C. Andersen et al.   G3-Genes Genomes Genetics

The Emergence of Resistance to the Benzimidazole Anthlemintics in Parasitic Nematodes of Livestock Is Characterised by Multiple Independent Hard and Soft Selective Sweeps

(2015) Elizabeth Redman et al.   PLoS Neglected Tropical Diseases

Transgenically expressed Parascaris P-glycoprotein-11 can modulate ivermectin susceptibility in Caenorhabditis elegans

(2015) I. Jana I. Janssen et al.   International Journal for Parasitology-Drugs and Drug Resistance

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

COPASutils: An R Package for Reading, Processing, and Visualizing Data from COPAS Large-Particle Flow Cytometers

(2014) Tyler C. Shimko et al.   PLoS One

Chasing helminths and their economic impact on farmed ruminants

(2014) Johannes Charlier et al.   TRENDS IN PARASITOLOGY

A Variant in the Neuropeptide Receptor npr-1 is a Major Determinant of Caenorhabditis elegans Growth and Physiology

(2014) Erik C. Andersen et al.   PLoS Genetics

The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected Tropical Diseases

(2014) Peter J. Hotez et al.   PLoS Neglected Tropical Diseases

Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid

(2013) Harald Frankowski et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Finding the sources of missing heritability in a yeast cross

(2013) Joshua S. Bloom et al.   NATURE

Haemonchus contortus as a paradigm and model to study anthelmintic drug resistance

(2013) JOHN S. GILLEARD   PARASITOLOGY

History of Avermectin and Ivermectin, with Notes on the History of Other Macrocyclic Lactone Antiparasitic Agents

(2012) William C. Campbell   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Natural Variation in a Chloride Channel Subunit Confers Avermectin Resistance in C. elegans

(2012) R. Ghosh et al.   SCIENCE

A Research Agenda for Helminth Diseases of Humans: The Problem of Helminthiases

(2012) Sara Lustigman et al.   PLoS Neglected Tropical Diseases

A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data

(2011) H. Li   BIOINFORMATICS

Gene expression changes in a P-glycoprotein (Tci-pgp-9) putatively associated with ivermectin resistance in Teladorsagia circumcincta

(2011) Alison J. Dicker et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Integrated parasite management: Products for adoption by the Australian sheep industry

(2011) L.P. Kahn et al.   VETERINARY PARASITOLOGY

Ridge Regression and Other Kernels for Genomic Selection with R Package rrBLUP

(2011) Jeffrey B. Endelman   Plant Genome

Selection at Linked Sites Shapes Heritable Phenotypic Variation in C. elegans

(2010) M. V. Rockman et al.   SCIENCE

Anthelmintic resistance in nematode parasites of cattle: a global issue?

(2010) Ian A. Sutherland et al.   TRENDS IN PARASITOLOGY

Rescuing the bottom billion through control of neglected tropical diseases

(2009) Peter J Hotez et al.   LANCET

Genetic variation in resistance to mixed, predominantlyTeladorsagia circumcinctanematode infections of sheep: from heritabilities to gene identification

(2009) M. J. STEAR et al.   PARASITE IMMUNOLOGY

Recombinational Landscape and Population Genomics of Caenorhabditis elegans

(2009) Matthew V. Rockman et al.   PLoS Genetics