Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resistance to benzimidazoles

Modernizing the World Health Organization List of Essential Medicines for Preventing and Controlling Cardiovascular Diseases

(2018) Sandeep P. Kishore et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Sorption of thiabendazole in sub-tropical Brazilian soils

(2017) Odilon França de Oliveira Neto et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

WormBase ParaSite − a comprehensive resource for helminth genomics

(2017) Kevin L. Howe et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons

(2017) Stefan Zdraljevic et al.   PLoS Genetics

Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity

(2017) Stephen R. Doyle et al.   PLoS Neglected Tropical Diseases

Comparison of constitutive and thiabendazole-induced expression of five cytochrome P450 genes in fourth-stage larvae of Haemonchus contortus isolates with different drug susceptibility identifies one gene with high constitutive expression in a multi-resistant isolate

(2017) Esra Yilmaz et al.   International Journal for Parasitology-Drugs and Drug Resistance

Reduced efficacy of albendazole against Ascaris lumbricoides in Rwandan schoolchildren

(2017) Jürgen Krücken et al.   International Journal for Parasitology-Drugs and Drug Resistance

Benzimidazole resistance in helminths: From problem to diagnosis

(2016) Luis Fernando Viana Furtado et al.   ACTA TROPICA

Genotype Imputation with Millions of Reference Samples

(2016) Brian L. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

RVTESTS: an efficient and comprehensive tool for rare variant association analysis using sequence data: Table 1.

(2016) Xiaowei Zhan et al.   BIOINFORMATICS

Albendazole in environment: faecal concentrations in lambs and impact on lower development stages of helminths and seed germination

(2016) Lukáš Prchal et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length

(2016) Daniel E. Cook et al.   GENETICS

Drug Discovery in Fish, Flies, and Worms

(2016) Kevin Strange   ILAR JOURNAL

CeNDR, theCaenorhabditis elegansnatural diversity resource

(2016) Daniel E. Cook et al.   NUCLEIC ACIDS RESEARCH

Selection on a Subunit of the NURF Chromatin Remodeler Modifies Life History Traits in a Domesticated Strain of Caenorhabditis elegans

(2016) Edward E. Large et al.   PLoS Genetics

DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans

(2016) Erin Munkácsy et al.   PLoS Genetics

Predicting Resistance by Mutagenesis: Lessons from 45 Years of MBC Resistance

(2016) Nichola J. Hawkins et al.   Frontiers in Microbiology

The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length

(2016) Daniel E. Cook et al.   GENETICS

NHR-176 regulatescyp-35d1to control hydroxylation-dependent metabolism of thiabendazole inCaenorhabditis elegans

(2015) Laura M. Jones et al.   BIOCHEMICAL JOURNAL

High Efficiency, Homology-Directed Genome Editing in Caenorhabditis elegans Using CRISPR-Cas9 Ribonucleoprotein Complexes

(2015) A. Paix et al.   GENETICS

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

WormBase 2016: expanding to enable helminth genomic research

(2015) Kevin L. Howe et al.   NUCLEIC ACIDS RESEARCH

The Dfam database of repetitive DNA families

(2015) Robert Hubley et al.   NUCLEIC ACIDS RESEARCH

A Co-CRISPR Strategy for Efficient Genome Editing in Caenorhabditis elegans

(2014) Heesun Kim et al.   GENETICS

PopGenome: An Efficient Swiss Army Knife for Population Genomic Analyses in R

(2014) Bastian Pfeifer et al.   MOLECULAR BIOLOGY AND EVOLUTION

COPASutils: An R Package for Reading, Processing, and Visualizing Data from COPAS Large-Particle Flow Cytometers

(2014) Tyler C. Shimko et al.   PLoS One

Chasing helminths and their economic impact on farmed ruminants

(2014) Johannes Charlier et al.   TRENDS IN PARASITOLOGY

A Variant in the Neuropeptide Receptor npr-1 is a Major Determinant of Caenorhabditis elegans Growth and Physiology

(2014) Erik C. Andersen et al.   PLoS Genetics

The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected Tropical Diseases

(2014) Peter J. Hotez et al.   PLoS Neglected Tropical Diseases

A bioassay for the detection of benzimidazoles reveals their presence in a range of environmental samples

(2014) Terence S. Crofts et al.   Frontiers in Microbiology

Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions

(2014) Andrew C. Kotze et al.   International Journal for Parasitology-Drugs and Drug Resistance

Hookworm Infection among School Age Children in Kintampo North Municipality, Ghana: Nutritional Risk Factors and Response to Albendazole Treatment

(2013) Debbie Humphries et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Characterization and comparative analysis of the complete Haemonchus contortus β-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes

(2013) Gary Ian Saunders et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Towards the identification of the binding site of benzimidazoles to β-tubulin of Trichinella spiralis: Insights from computational and experimental data

(2013) Rodrigo Aguayo-Ortiz et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Molecular basis for benzimidazole resistance from a novel β-tubulin binding site model

(2013) Rodrigo Aguayo-Ortiz et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Phylogenetic Characterization of β-Tubulins and Development of Pyrosequencing Assays for Benzimidazole Resistance in Cattle Nematodes

(2013) Janina Demeler et al.   PLoS One

Genetic and Molecular Basis of Drug Resistance and Species-Specific Drug Action in Schistosome Parasites

(2013) C. L. L. Valentim et al.   SCIENCE

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity

(2012) Erik C Andersen et al.   NATURE GENETICS

Natural Variation in a Chloride Channel Subunit Confers Avermectin Resistance in C. elegans

(2012) R. Ghosh et al.   SCIENCE

A Research Agenda for Helminth Diseases of Humans: The Problem of Helminthiases

(2012) Sara Lustigman et al.   PLoS Neglected Tropical Diseases

Introgression of Ivermectin Resistance Genes into a Susceptible Haemonchus contortus Strain by Multiple Backcrossing

(2012) Elizabeth Redman et al.   PLoS Pathogens

The variant call format and VCFtools

(2011) P. Danecek et al.   BIOINFORMATICS

A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data

(2011) H. Li   BIOINFORMATICS

Intraflagellar transport delivers tubulin isotypes to sensory cilium middle and distal segments

(2011) Limin Hao et al.   NATURE CELL BIOLOGY

Ridge Regression and Other Kernels for Genomic Selection with R Package rrBLUP

(2011) Jeffrey B. Endelman   Plant Genome

Pooled Association Tests for Rare Variants in Exon-Resequencing Studies

(2010) Alkes L. Price et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

The Multipurpose 15-Protofilament Microtubules in C. elegans Have Specific Roles in Mechanosensation

(2009) Alexander Bounoutas et al.   CURRENT BIOLOGY

Genetic variation in resistance to mixed, predominantlyTeladorsagia circumcinctanematode infections of sheep: from heritabilities to gene identification

(2009) M. J. STEAR et al.   PARASITE IMMUNOLOGY

The use of DNA markers to map anthelmintic resistance loci in an intraspecific cross of Haemonchus contortus

(2009) P. W. HUNT et al.   PARASITOLOGY

Efficient Control of Population Structure in Model Organism Association Mapping

(2008) H. M. Kang et al.   GENETICS