Immune cells fold and damage fungal hyphae

RHOA-mediated mechanical force generation through Dectin-1

(2020) Rohan P. Choraghe et al.   JOURNAL OF CELL SCIENCE

Mechanical force-induced morphology changes in a human fungal pathogen

(2020) Charles Puerner et al.   BMC BIOLOGY

Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides

(2019) Philip P. Ostrowski et al.   DEVELOPMENTAL CELL

Phospholipids: Pulling Back the Actin Curtain for Granule Delivery to the Immune Synapse

(2019) Christian M. Gawden-Bone et al.   Frontiers in Immunology

Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion

(2019) Arnab Pradhan et al.   Nature Communications

A novel 4-dimensional live-cell imaging system to study leukocyte-endothelial dynamics in ANCA-associated vasculitis

(2019) Catriona A. Walls et al.   AUTOIMMUNITY

Probing the mechanical landscape – new insights into podosome architecture and mechanics

(2019) Koen van den Dries et al.   JOURNAL OF CELL SCIENCE

Host Control of Fungal Infections: Lessons from Basic Studies and Human Cohorts

(2018) Michail S. Lionakis et al.   Annual Review of Immunology

Glucose Homeostasis Is Important for Immune Cell Viability during Candida Challenge and Host Survival of Systemic Fungal Infection

(2018) Timothy M. Tucey et al.   Cell Metabolism

The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis

(2018) Ivy M. Dambuza et al.   PLoS Pathogens

Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes

(2018) Michelle E Maxson et al.   eLife

Mannan Molecular Substructures Control Nanoscale Glucan Exposure in Candida

(2018) Matthew S. Graus et al.   Cell Reports

Long-range self-organization of cytoskeletal myosin II filament stacks

(2017) Shiqiong Hu et al.   NATURE CELL BIOLOGY

Zinc Limitation Induces a Hyper-Adherent Goliath Phenotype in Candida albicans

(2017) Dhara Malavia et al.   Frontiers in Microbiology

Diffusion Barriers, Mechanical Forces, and the Biophysics of Phagocytosis

(2016) Philip P. Ostrowski et al.   DEVELOPMENTAL CELL

Interactions of fungal pathogens with phagocytes

(2016) Lars P. Erwig et al.   NATURE REVIEWS MICROBIOLOGY

Lactate signalling regulates fungal β-glucan masking and immune evasion

(2016) Elizabeth R. Ballou et al.   Nature Microbiology

Global analysis of fungal morphology exposes mechanisms of host cell escape

(2015) Teresa R. O’Meara et al.   Nature Communications

CR3 and Dectin-1 Collaborate in Macrophage Cytokine Response through Association on Lipid Rafts and Activation of Syk-JNK-AP-1 Pathway

(2015) Juin-Hua Huang et al.   PLoS Pathogens

Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly

(2015) Sari Tojkander et al.   eLife

The role of the cytoskeleton at the immunological synapse

(2014) Alex T. Ritter et al.   IMMUNOLOGICAL REVIEWS

Dectin-1–Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages

(2014) Jenny M. Tam et al.   JOURNAL OF INFECTIOUS DISEASES

Cdc42 GTPase dynamics control directional growth responses

(2014) A. C. Brand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Candida albicans Hypha Formation and Mannan Masking of β-Glucan Inhibit Macrophage Phagosome Maturation

(2014) Judith M. Bain et al.   mBio

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation

(2014) Jeanette Wagener et al.   PLoS Pathogens

Candida albicans Triggers NLRP3-Mediated Pyroptosis in Macrophages

(2013) Melanie Wellington et al.   EUKARYOTIC CELL

Stress adaptation in a pathogenic fungus

(2013) A. J. P. Brown et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

IRSp53 Mediates Podosome Formation via VASP in NIH-Src Cells

(2013) Tsukasa Oikawa et al.   PLoS One

α-Actinin and fimbrin cooperate with myosin II to organize actomyosin bundles during contractile-ring assembly

(2012) Damien Laporte et al.   MOLECULAR BIOLOGY OF THE CELL

Characterisation of Innate Fungal Recognition in the Lung

(2012) Inês Faro-Trindade et al.   PLoS One

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Stage Specific Assessment of Candida albicans Phagocytosis by Macrophages Identifies Cell Wall Composition and Morphogenesis as Key Determinants

(2012) Leanne E. Lewis et al.   PLoS Pathogens

Innate Antifungal Immunity: The Key Role of Phagocytes

(2011) Gordon D. Brown   Annual Review of Immunology

Phosphorylation of VASP by AMPK alters actin binding and occurs at a novel site

(2011) David M. Thomson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MAPKKK-independent Regulation of the Hog1 Stress-activated Protein Kinase inCandida albicans

(2011) Jill Cheetham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of Syk/CARD9 coupled C-type lectins in antifungal immunity

(2010) Rebecca A. Drummond et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Podosome-type adhesions and focal adhesions, so alike yet so different

(2008) M BLOCK et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Actin and Phosphoinositide Recruitment to Fully Formed Candida albicans Phagosomes in Mouse Macrophages

(2008) Sigrid E.M. Heinsbroek et al.   Journal of Innate Immunity

Stage-Specific Sampling by Pattern Recognition Receptors during Candida albicans Phagocytosis

(2008) Sigrid E. M. Heinsbroek et al.   PLoS Pathogens

Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins

(2008) Louise A. Walker et al.   PLoS Pathogens

An integrated model of the recognition of Candida albicans by the innate immune system

(2007) Mihai G. Netea et al.   NATURE REVIEWS MICROBIOLOGY