Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion

Exposure of Candida albicans β (1,3)-glucan is promoted by activation of the Cek1 pathway

(2019) Tian Chen et al.   PLoS Genetics

Host Control of Fungal Infections: Lessons from Basic Studies and Human Cohorts

(2018) Michail S. Lionakis et al.   Annual Review of Immunology

Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs

(2018) Carmen Herrero-de-Dios et al.   mBio

Mannan Molecular Substructures Control Nanoscale Glucan Exposure in Candida

(2018) Matthew S. Graus et al.   Cell Reports

Memory in Fungal Pathogens Promotes Immune Evasion, Colonisation, and Infection

(2018) Alistair J.P. Brown et al.   TRENDS IN MICROBIOLOGY

Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling

(2018) Arnab Pradhan et al.   mBio

Evasion of Immune Surveillance in Low Oxygen Environments Enhances Candida albicans Virulence

(2018) José Pedro Lopes et al.   mBio

Global regulatory roles of the cAMP/PKA pathway revealed by phenotypic, transcriptomic and phosphoproteomic analyses in a null mutant of the PKA catalytic subunit in Candida albicans

(2017) Chengjun Cao et al.   MOLECULAR MICROBIOLOGY

Elevated catalase expression in a fungal pathogen is a double-edged sword of iron

(2017) Arnab Pradhan et al.   PLoS Pathogens

Adaptation of Candida albicans to environmental pH induces cell wall remodelling and enhances innate immune recognition

(2017) Sarah L. Sherrington et al.   PLoS Pathogens

Zinc Limitation Induces a Hyper-Adherent Goliath Phenotype in Candida albicans

(2017) Dhara Malavia et al.   Frontiers in Microbiology

Interactions of fungal pathogens with phagocytes

(2016) Lars P. Erwig et al.   NATURE REVIEWS MICROBIOLOGY

β-glucan Exposure on the Fungal Cell Wall Tightly Correlates with Competitive Fitness of Candida Species in the Mouse Gastrointestinal Tract

(2016) XiaoHui Sem et al.   Frontiers in Cellular and Infection Microbiology

Anti-Immune Strategies of Pathogenic Fungi

(2016) Caroline M. Marcos et al.   Frontiers in Cellular and Infection Microbiology

Lactate signalling regulates fungal β-glucan masking and immune evasion

(2016) Elizabeth R. Ballou et al.   Nature Microbiology

An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism

(2015) Sanne P. Smeekens et al.   CYTOKINE

Microbial ecology of Antarctic aquatic systems

(2015) Ricardo Cavicchioli   NATURE REVIEWS MICROBIOLOGY

Modeling the Transcriptional Regulatory Network That Controls the Early Hypoxic Response in Candida albicans

(2014) Adnane Sellam et al.   EUKARYOTIC CELL

Masking of β(1-3)-Glucan in the Cell Wall of Candida albicans from Detection by Innate Immune Cells Depends on Phosphatidylserine

(2014) Sarah E. Davis et al.   INFECTION AND IMMUNITY

Novel insights into host-fungal pathogen interactions derived from live-cell imaging

(2014) Judith Bain et al.   Seminars in Immunopathology

Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels

(2014) Alistair J.P. Brown et al.   TRENDS IN MICROBIOLOGY

Mechanisms Underlying the Exquisite Sensitivity of Candida albicans to Combinatorial Cationic and Oxidative Stress That Enhances the Potent Fungicidal Activity of Phagocytes

(2014) D. Kaloriti et al.   mBio

Stress adaptation in a pathogenic fungus

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The RodA Hydrophobin on Aspergillus fumigatus Spores Masks Dectin-1- and Dectin-2-Dependent Responses and Enhances Fungal Survival In Vivo

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Fungal Iron Availability during Deep Seated Candidiasis Is Defined by a Complex Interplay Involving Systemic and Local Events

(2013) Joanna Potrykus et al.   PLoS Pathogens

Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1

(2013) Mohlopheni J. Marakalala et al.   PLoS Pathogens

Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis

(2012) Agostinho Carvalho et al.   Cellular & Molecular Immunology

Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen

(2012) Iuliana V. Ene et al.   CELLULAR MICROBIOLOGY

The Cryptococcus neoformans Capsule: a Sword and a Shield

(2012) T. R. O'Meara et al.   CLINICAL MICROBIOLOGY REVIEWS

C-type lectin receptors orchestrate antifungal immunity

(2012) Sarah E Hardison et al.   NATURE IMMUNOLOGY

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Post-Transcriptional Regulation of the Sef1 Transcription Factor Controls the Virulence of Candida albicans in Its Mammalian Host

(2012) Changbin Chen et al.   PLoS Pathogens

Candida albicans Scavenges Host Zinc via Pra1 during Endothelial Invasion

(2012) Francesco Citiulo et al.   PLoS Pathogens

Innate Antifungal Immunity: The Key Role of Phagocytes

(2011) Gordon D. Brown   Annual Review of Immunology

An Iron Homeostasis Regulatory Circuit with Reciprocal Roles in Candida albicans Commensalism and Pathogenesis

(2011) Changbin Chen et al.   Cell Host & Microbe

Intestinal Resident Yeast Candida glabrata Requires Cyb2p-Mediated Lactate Assimilation to Adapt in Mouse Intestine

(2011) Keigo Ueno et al.   PLoS One

Regulation of the Hypoxic Response in Candida albicans

(2010) John M. Synnott et al.   EUKARYOTIC CELL

Activation of the heat shock transcription factor Hsf1 is essential for the full virulence of the fungal pathogen Candida albicans

(2010) Susan Nicholls et al.   FUNGAL GENETICS AND BIOLOGY

The Candida Th17 response is dependent on mannan- and  -glucan-induced prostaglandin E2

(2010) S. P. Smeekens et al.   INTERNATIONAL IMMUNOLOGY

A Multifunctional Mannosyltransferase Family in Candida albicans Determines Cell Wall Mannan Structure and Host-Fungus Interactions

(2010) Héctor M. Mora-Montes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early Stop Polymorphism in Human DECTIN‐1 Is Associated with IncreasedCandidaColonization in Hematopoietic Stem Cell Transplant Recipients

(2009) Theo S. Plantinga et al.   CLINICAL INFECTIOUS DISEASES

Goa1p ofCandida albicansLocalizes to the Mitochondria during Stress and Is Required for Mitochondrial Function and Virulence

(2009) Adrienne Bambach et al.   EUKARYOTIC CELL

Candida albicans iron acquisition within the host

(2009) Ricardo S. Almeida et al.   FEMS YEAST RESEARCH

Glucose Promotes Stress Resistance in the Fungal Pathogen Candida albicans

(2009) Alexandra Rodaki et al.   MOLECULAR BIOLOGY OF THE CELL

Adaptive prediction of environmental changes by microorganisms

(2009) Amir Mitchell et al.   NATURE

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dynamic, Morphotype-Specific Candida albicans β-Glucan Exposure during Infection and Drug Treatment

(2008) Robert T. Wheeler et al.   PLoS Pathogens