Deletion of arginase 2 attenuates neuroinflammation in an experimental model of optic neuritis

The proportion of myeloid-derived suppressor cells in the spleen is related to the severity of the clinical course and tissue damage extent in a murine model of multiple sclerosis

(2020) Carolina Melero-Jerez et al.   NEUROBIOLOGY OF DISEASE

Changes of B cell subsets in central pathological process of autoimmune encephalomyelitis in mice

(2019) Yingqiong Xiong et al.   BMC IMMUNOLOGY

Deletion of Arginase 2 Ameliorates Retinal Neurodegeneration in a Mouse Model of Multiple Sclerosis

(2019) Chithra D. Palani et al.   MOLECULAR NEUROBIOLOGY

The presence and suppressive activity of myeloid-derived suppressor cells are potentiated after interferon-β treatment in a murine model of multiple sclerosis

(2019) Carolina Melero-Jerez et al.   NEUROBIOLOGY OF DISEASE

Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis

(2019) Jing Jin et al.   Acta Neuropathologica Communications

When encephalitogenic T cells collaborate with microglia in multiple sclerosis

(2019) Yifei Dong et al.   Nature Reviews Neurology

Nav1.6 promotes inflammation and neuronal degeneration in a mouse model of multiple sclerosis

(2019) Barakat Alrashdi et al.   Journal of Neuroinflammation

Dexras1 Deletion and Iron Chelation Promote Neuroprotection in Experimental Optic Neuritis

(2019) Reas S. Khan et al.   Scientific Reports

Deficient arginase II expression without alteration in arginase I expression attenuated experimental autoimmune encephalomyelitis in mice

(2018) Mariam Choudry et al.   IMMUNOLOGY

Laquinimod protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model

(2018) Anna T. Wilmes et al.   Journal of Neuroinflammation

Early Nodal and Paranodal Disruption in Autoimmune Optic Neuritis

(2018) Aleksandar Stojic et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Arginase: A Multifaceted Enzyme Important in Health and Disease

(2018) R. William Caldwell et al.   PHYSIOLOGICAL REVIEWS

The Role of Astrocytes in Multiple Sclerosis

(2018) Gerald Ponath et al.   Frontiers in Immunology

Cyclic AMP Pathway Suppress Autoimmune Neuroinflammation by Inhibiting Functions of Encephalitogenic CD4 T Cells and Enhancing M2 Macrophage Polarization at the Site of Inflammation

(2018) Tatyana Veremeyko et al.   Frontiers in Immunology

Calcitonin gene-related peptide decreases IL-1beta, IL-6 as well as Ym1, Arg1, CD163 expression in a brain tissue context-dependent manner while ameliorating experimental autoimmune encephalomyelitis

(2018) Ilaria Rossetti et al.   JOURNAL OF NEUROIMMUNOLOGY

Further Evidence on Efficacy of Diet Supplementation with Fatty Acids in Ocular Pathologies: Insights from the EAE Model of Optic Neuritis

(2018) Filippo Locri et al.   Nutrients

Retinal Neuroprotection From Optic Nerve Trauma by Deletion of Arginase 2

(2018) Zhimin Xu et al.   Frontiers in Neuroscience

Sequential phases of RGC axonal and somatic injury in EAE mice examined using DTI and OCT

(2018) Christopher Nishioka et al.   Multiple Sclerosis and Related Disorders

Connexin 30 Deficiency Attenuates Chronic but Not Acute Phases of Experimental Autoimmune Encephalomyelitis Through Induction of Neuroprotective Microglia

(2018) Mei Fang et al.   Frontiers in Immunology

Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy

(2017) Yanji Zhu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Different distributions of M1 and M2 macrophages in a mouse model of laser-induced choroidal neovascularization

(2017) Yedi Zhou et al.   Molecular Medicine Reports

Macrophage physiology in the eye

(2017) Holly R Chinnery et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Targeting Different Monocyte/Macrophage Subsets Has No Impact on Outcome in Experimental Stroke

(2017) Antje Schmidt et al.   STROKE

Optic Nerve Degeneration after Retinal Ischemia/Reperfusion in a Rodent Model

(2017) Marina Renner et al.   Frontiers in Cellular Neuroscience

Arginase-1 is expressed exclusively by infiltrating myeloid cells in CNS injury and disease

(2016) Andrew D. Greenhalgh et al.   BRAIN BEHAVIOR AND IMMUNITY

Retinal and Optic Nerve Damage is Associated with Early Glial Responses in an Experimental Autoimmune Glaucoma Model

(2016) Rozina Noristani et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Increase of Alternatively Activated Antigen Presenting Cells in Active Experimental Autoimmune Encephalomyelitis

(2016) Beatrice Wasser et al.   Journal of Neuroimmune Pharmacology

Microglia response in retina and optic nerve in chronic experimental autoimmune encephalomyelitis

(2016) Lioba Horstmann et al.   JOURNAL OF NEUROIMMUNOLOGY

Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury

(2016) Esraa Shosha et al.   Cell Death & Disease

Prior regular exercise improves clinical outcome and reduces demyelination and axonal injury in experimental autoimmune encephalomyelitis

(2015) Danielle Bernardes et al.   JOURNAL OF NEUROCHEMISTRY

Purkinje Cell Pathology and Loss in Multiple Sclerosis Cerebellum

(2014) Juliana Redondo et al.   BRAIN PATHOLOGY

Re-evaluating the treatment of acute optic neuritis

(2014) Jeffrey L Bennett et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Microglia activation in multiple sclerosis black holes predicts outcome in progressive patients: An in vivo [(11)C](R)-PK11195-PET pilot study

(2014) Paolo Giannetti et al.   NEUROBIOLOGY OF DISEASE

The synthetic retinoid Am80 delays recovery in a model of multiple sclerosis by modulating myeloid-derived suppressor cell fate and viability

(2014) Verónica Moliné-Velázquez et al.   NEUROBIOLOGY OF DISEASE

Axonal transport rate decreased at the onset of optic neuritis in EAE mice

(2014) Tsen-Hsuan Lin et al.   NEUROIMAGE

Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolism

(2014) S P Narayanan et al.   Cell Death & Disease

Incidence and prevalence of multiple sclerosis in Europe: a systematic review

(2013) Elaine Kingwell et al.   BMC Neurology

The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina

(2013) Allen R. Rodriguez et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis

(2013) Wan-fu Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic inactivation of the p66 isoform of ShcA is neuroprotective in a murine model of multiple sclerosis

(2012) Kimmy G. Su et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis

(2012) Roberta Brambilla et al.   Journal of Neuroinflammation

Modulation of nitric oxide synthase by arginase and methylated arginines during the acute phase of experimental multiple sclerosis

(2012) Srdjan Ljubisavljevic et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Multiple sclerosis: new measures to monitor the disease

(2012) Massimo Filippi et al.   LANCET NEUROLOGY

The reduced glutathione and S-nitrosothiols levels in acute phase of experimental demyelination – Pathophysiological approach and possible clinical relevancy

(2012) S. Ljubisavljevic et al.   NEUROSCIENCE

Ganglion Cell Loss in Relation to Visual Disability in Multiple Sclerosis

(2012) Scott D. Walter et al.   OPHTHALMOLOGY

Myeloid-Derived Suppressor Cells Limit the Inflammation by Promoting T Lymphocyte Apoptosis in the Spinal Cord of a Murine Model of Multiple Sclerosis

(2011) Verónica Moliné-Velázquez et al.   BRAIN PATHOLOGY

Optic neuritis

(2011) D Pau et al.   EYE

The molecular basis of neurodegeneration in multiple sclerosis

(2011) Hans Lassmann et al.   FEBS LETTERS

Suppression of EAE and prevention of blood–brain barrier breakdown after vaccination with novel bifunctional peptide inhibitor

(2011) Ahmed H. Badawi et al.   NEUROPHARMACOLOGY

Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis

(2011) A. Castegna et al.   NEUROSCIENCE

Aminoguanidine andN-acetyl-cysteine supress oxidative and nitrosative stress in EAE rat brains

(2011) Srdjan Ljubisavljevic et al.   REDOX REPORT

Bilateral and recurrent optic neuritis in multiple sclerosis

(2010) J. Burman et al.   ACTA NEUROLOGICA SCANDINAVICA

Are current disease-modifying therapeutics in multiple sclerosis justified on the basis of studies in experimental autoimmune encephalomyelitis?

(2010) Nasr Farooqi et al.   JOURNAL OF NEUROCHEMISTRY

Blood–brain barrier disruption and enhanced vascular permeability in the multiple sclerosis model EAE

(2010) Jami Bennett et al.   JOURNAL OF NEUROIMMUNOLOGY

Activated Microglia Mediate Axoglial Disruption That Contributes to Axonal Injury in Multiple Sclerosis

(2010) Owain W. Howell et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mechanisms of acute axonal degeneration in the optic nerve in vivo

(2010) J. Knoferle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Synthesis of Spermidine as a Result of Upregulation of Arginase I Promotes Axonal Regeneration in Culture and In Vivo

(2009) K. Deng et al.   JOURNAL OF NEUROSCIENCE

Temporal trends in the incidence of multiple sclerosis: A systematic review

(2008) A. Alonso et al.   NEUROLOGY

Optical coherence tomography: a window into the mechanisms of multiple sclerosis

(2008) Elliot M Frohman et al.   Nature clinical practice. Neurology

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark