Nav1.6 promotes inflammation and neuronal degeneration in a mouse model of multiple sclerosis

MiR-30b-5p attenuates oxaliplatin-induced peripheral neuropathic pain through the voltage-gated sodium channel Nav1.6 in rats

(2019) Lei Li et al.   NEUROPHARMACOLOGY

Laquinimod protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model

(2018) Anna T. Wilmes et al.   Journal of Neuroinflammation

In vivo imaging of adeno-associated viral vector labelled retinal ganglion cells

(2018) Corey A. Smith et al.   Scientific Reports

New Insights into the Role of IL-1β in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

(2017) Chih-Chung Lin et al.   JOURNAL OF IMMUNOLOGY

Sodium channels in astroglia and microglia

(2016) Laura W. Pappalardo et al.   GLIA

Microglia response in retina and optic nerve in chronic experimental autoimmune encephalomyelitis

(2016) Lioba Horstmann et al.   JOURNAL OF NEUROIMMUNOLOGY

Phenytoin for neuroprotection in patients with acute optic neuritis: a randomised, placebo-controlled, phase 2 trial

(2016) Rhian Raftopoulos et al.   LANCET NEUROLOGY

Selective Blocking Effects of 4,9-Anhydrotetrodotoxin, Purified from a Crude Mixture of Tetrodotoxin Analogues, on NaV1.6 Channels and Its Chemical Aspects

(2015) Noriyoshi Teramoto et al.   Marine Drugs

Imaging retinal ganglion cells: Enabling experimental technology for clinical application

(2015) Corey A. Smith et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Interactions between Neutrophils, Th17 Cells, and Chemokines during the Initiation of Experimental Model of Multiple Sclerosis

(2014) Dagmara Weronika Wojkowska et al.   MEDIATORS OF INFLAMMATION

Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis

(2014) Manuel A. Friese et al.   Nature Reviews Neurology

Targeted CNS delivery using human MiniPromoters and demonstrated compatibility with adeno-associated viral vectors

(2014) Charles N de Leeuw et al.   Molecular Therapy-Methods & Clinical Development

Optical neuritis induced by different concentrations of myelin oligodendrocyte glycoprotein presents different profiles of the inflammatory process

(2013) Rubens Murilo Gibaile Soares et al.   AUTOIMMUNITY

Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis

(2013) Damineh Morsali et al.   BRAIN

The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina

(2013) Allen R. Rodriguez et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Inflammatory demyelination induces glia alterations and ganglion cell loss in the retina of an experimental autoimmune encephalomyelitis model

(2013) Lioba Horstmann et al.   Journal of Neuroinflammation

Evidence for a role of Nav1.6 in facilitating increases in neuronal hyperexcitability during epileptogenesis

(2013) Nicholas J. Hargus et al.   JOURNAL OF NEUROPHYSIOLOGY

Axonal expression of sodium channels and neuropathology of the plaques in multiple sclerosis

(2013) Adel Bouafia et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Neurological perspectives on voltage-gated sodium channels

(2012) N. Eijkelkamp et al.   BRAIN

Capture, crawl, cross: the T cell code to breach the blood–brain barriers

(2012) Britta Engelhardt et al.   TRENDS IN IMMUNOLOGY

Differential patterns of spinal cord pathology induced by MP4, MOG peptide 35-55, and PLP peptide 178-191 in C57BL/6 mice

(2011) STEFANIE KUERTEN et al.   APMIS

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

(2011) Cris S Constantinescu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Optic Neuritis and Retinal Ganglion Cell Loss in a Chronic Murine Model of Multiple Sclerosis

(2011) Thomas A. Quinn et al.   Frontiers in Neurology

Lamotrigine for neuroprotection in secondary progressive multiple sclerosis: a randomised, double-blind, placebo-controlled, parallel-group trial

(2010) Raju Kapoor et al.   LANCET NEUROLOGY

Mechanisms of axonal injury: internodal nanocomplexes and calcium deregulation

(2010) David P. Stirling et al.   TRENDS IN MOLECULAR MEDICINE

Multiple sclerosis: Geoepidemiology, genetics and the environment

(2009) Ron Milo et al.   AUTOIMMUNITY REVIEWS

Sodium channel activity modulates multiple functions in microglia

(2009) Joel A. Black et al.   GLIA

Regulation of Podosome Formation in Macrophages by a Splice Variant of the Sodium ChannelSCN8A

(2009) Michael D. Carrithers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optic nerve diffusion changes and atrophy jointly predict visual dysfunction after optic neuritis

(2009) Scott Kolbe et al.   NEUROIMAGE

Inflammatory demyelination induces axonal injury and retinal ganglion cell apoptosis in experimental optic neuritis

(2008) Kenneth S. Shindler et al.   EXPERIMENTAL EYE RESEARCH

Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection

(2008) M Hellström et al.   GENE THERAPY

Loss of Na+ channel β2 subunits is neuroprotective in a mouse model of multiple sclerosis

(2008) Heather A. O'Malley et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

(2008) Satoshi Serada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Disease: sodium channels and neuroprotection in multiple sclerosis—current status

(2008) Stephen G Waxman   Nature clinical practice. Neurology