Mango (Mangifera indica L.) Polyphenols: Anti-Inflammatory Intestinal Microbial Health Benefits, and Associated Mechanisms of Actions

The Interactions between Polyphenols and Microorganisms, Especially Gut Microbiota

(2021) Małgorzata Makarewicz et al.   Antioxidants

Pasteurized Akkermansia muciniphila protects from fat mass gain but not from bone loss

(2020) Lina Lawenius et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Colorectal cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Mango (Mangifera indica L.) polyphenols reduce IL-8, GRO, and GM-SCF plasma levels and increase Lactobacillus species in a pilot study in patients with inflammatory bowel disease

(2020) Hyemee Kim et al.   NUTRITION RESEARCH

Changes in Intestinal Microbiota and Predicted Metabolic Pathways During Colonic Fermentation of Mango (Mangifera indica L.)—Based Bar Indigestible Fraction

(2020) Wilbert Gutiérrez-Sarmiento et al.   Nutrients

Proanthocyanidin-Rich Grape Seed Extract Reduces Inflammation and Oxidative Stress and Restores Tight Junction Barrier Function in Caco-2 Colon Cells

(2020) Rameshprabu Nallathambi et al.   Nutrients

Mango (Mangifera indica L.): a magnificent plant with cancer preventive and anticancer therapeutic potential

(2020) Bilal Mirza et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Acute Effects of a Polyphenol-Rich Leaf Extract of Mangifera indica L. (Zynamite) on Cognitive Function in Healthy Adults: A Double-Blind, Placebo-Controlled Crossover Study

(2020) Emma L. Wightman et al.   Nutrients

Human resident gut microbe Bacteroides thetaiotaomicron regulates colonic neuronal innervation and neurogenic function

(2020) Rubina Aktar et al.   Gut Microbes

Human-derived Bifidobacterium dentium modulates the mammalian serotonergic system and gut-brain axis

(2020) Melinda A. Engevik et al.   Cellular and Molecular Gastroenterology and Hepatology

Tannic acid prevents post-weaning diarrhea by improving intestinal barrier integrity and function in weaned piglets

(2020) Jie Yu et al.   Journal of Animal Science and Biotechnology

Gut microbes from the phylogenetically diverse genus Eubacterium and their various contributions to gut health

(2020) Arghya Mukherjee et al.   Gut Microbes

Comprehensive ESI-Q TRAP-MS/MS based characterization of metabolome of two mango (Mangifera indica L) cultivars from China

(2020) Lin Tan et al.   Scientific Reports

Role of Intestinal Microbiota in the Bioavailability and Physiological Functions of Dietary Polyphenols

(2019) Kyuichi Kawabata et al.   MOLECULES

Emerging Health Concepts in the Probiotics Field: Streamlining the Definitions

(2019) Rebeca Martín et al.   Frontiers in Microbiology

Polyphenols and Intestinal Permeability: Rationale and Future Perspectives

(2019) Stefano Bernardi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Defining Dysbiosis for a Cluster of Chronic Diseases

(2019) Lamont J. Wilkins et al.   Scientific Reports

Chemical Composition of Mango (Mangifera indica L.) Fruit: Nutritional and Phytochemical Compounds

(2019) Maria Elena Maldonado-Celis et al.   Frontiers in Plant Science

The Anti-Cancer Effect of Mangifera indica L. Peel Extract is Associated to γH2AX-mediated Apoptosis in Colon Cancer Cells

(2019) Marianna Lauricella et al.   Antioxidants

Polyphenol-rich Mango (Mangifera indica L.) Ameliorate Functional Constipation Symptoms in Humans beyond Equivalent Amount of Fiber

(2018) Vinicius P. Venancio et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Gallic Acid Content and an Antioxidant Mechanism Are Responsible for the Antiproliferative Activity of ‘Ataulfo’ Mango Peel on LS180 Cells

(2018) Gustavo. Velderrain-Rodríguez et al.   MOLECULES

Polyphenolic derivatives from mango ( Mangifera Indica L.) modulate fecal microbiome, short-chain fatty acids production and the HDAC1/AMPK/LC3 axis in rats with DSS-induced colitis

(2018) Hyemee Kim et al.   Journal of Functional Foods

Tannase improves gallic acid bioaccessibility and maintains the quality of mango juice

(2018) Maritza A. Sirven et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

The gut microbiome: Relationships with disease and opportunities for therapy

(2018) Juliana Durack et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Body Mass Index as a Determinant of Systemic Exposure to Gallotannin Metabolites during 6-Week Consumption of Mango (Mangifera indica L.) and Modulation of Intestinal Microbiota in Lean and Obese Individuals

(2018) Ryan C. Barnes et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Gallic acid improved inflammation via NF-κB pathway in TNBS-induced ulcerative colitis

(2018) Lei Zhu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Food quality and nutraceutical value of nine cultivars of mango (Mangifera indica L.) fruits grown in Mediterranean subtropical environment

(2018) Carla Gentile et al.   FOOD CHEMISTRY

Gallic acid disruption of Aβ1–42 aggregation rescues cognitive decline of APP/PS1 double transgenic mouse

(2018) Mei Yu et al.   NEUROBIOLOGY OF DISEASE

The effect of quercetin on the pharmacokinetics of chlorzoxazone, a CYP2E1 substrate, in healthy subjects

(2017) Satish Kumar Bedada et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Gut microbiota functions: metabolism of nutrients and other food components

(2017) Ian Rowland et al.   EUROPEAN JOURNAL OF NUTRITION

A Review on Ethnopharmacological Applications, Pharmacological Activities, and Bioactive Compounds of Mangifera indica (Mango)

(2017) Meran Keshawa Ediriweera et al.   Evidence-based Complementary and Alternative Medicine

Prebiotic effect of predigested mango peel on gut microbiota assessed in a dynamic in vitro model of the human colon (TIM-2)

(2017) Sonia G. Sáyago-Ayerdi et al.   FOOD RESEARCH INTERNATIONAL

Methylation of cytokines gene promoters in IL-1β-treated human intestinal epithelial cells

(2017) Fabio Caradonna et al.   INFLAMMATION RESEARCH

In vitro inhibition of human CYP2E1 and CYP3A by quercetin and myricetin in hepatic microsomes is not gender dependent

(2017) Johanna Östlund et al.   TOXICOLOGY

Mangos and their bioactive components: adding variety to the fruit plate for health

(2017) Britt M. Burton-Freeman et al.   Food & Function

Processing ‘Ataulfo’ Mango into Juice Preserves the Bioavailability and Antioxidant Capacity of Its Phenolic Compounds

(2017) Ana Quirós-Sauceda et al.   Nutrients

Gut microbiota as a potential target of metabolic syndrome: the role of probiotics and prebiotics

(2017) Mingqian He et al.   Cell and Bioscience

Polyphenols associated with dietary fibers in plant foods: molecular interactions and bioaccessibility

(2017) Gustavo A González-Aguilar et al.   Current Opinion in Food Science

Re-evaluation of the mechanisms of dietary fibre and implications for macronutrient bioaccessibility, digestion and postprandial metabolism

(2016) Myriam M.-L. Grundy et al.   BRITISH JOURNAL OF NUTRITION

Proanthocyanidins and hydrolysable tannins: occurrence, dietary intake and pharmacological effects

(2016) Antonella Smeriglio et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mangiferin attenuates DSS colitis in mice: Molecular docking and in vivo approach

(2016) Sahil Somani et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Ellagitannins, gallotannins and their metabolites- the contribution to the anti-inflammatory effect of food products and medicinal plants

(2016) Anna Kiss et al.   CURRENT MEDICINAL CHEMISTRY

Mangiferin corrects the imbalance of Th17/Treg cells in mice with TNBS-induced colitis

(2016) Su-Min Lim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mango Supplementation Modulates Gut Microbial Dysbiosis and Short-Chain Fatty Acid Production Independent of Body Weight Reduction in C57BL/6 Mice Fed a High-Fat Diet

(2016) Babajide Ojo et al.   JOURNAL OF NUTRITION

Inhibitory Effects of Eight Green Tea Catechins on Cytochrome P450 1A2, 2C9, 2D6, and 3A4 Activities

(2016) Takashi Satoh et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Mango polyphenolics reduce inflammation in intestinal colitis-involvement of the miR-126/PI3K/AKT/mTOR axis in vitro and in vivo

(2016) Hyemee Kim et al.   MOLECULAR CARCINOGENESIS

Long-Term Mangiferin Extract Treatment Improves Central Pathology and Cognitive Deficits in APP/PS1 Mice

(2016) Carmen Infante-Garcia et al.   MOLECULAR NEUROBIOLOGY

Comparison of anti-inflammatory mechanisms of mango (Mangifera IndicaL.) and pomegranate (Punica GranatumL.) in a preclinical model of colitis

(2016) Hyemee Kim et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Urinary metabolites from mango (Mangifera indicaL. cv. Keitt) galloyl derivatives and in vitro hydrolysis of gallotannins in physiological conditions

(2016) Ryan C. Barnes et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Therapeutic potentials of bioactive compounds from mango fruit wastes

(2016) Afifa Asif et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut

(2016) Audrey Rivière et al.   Frontiers in Microbiology

Evaluation of the proximate composition, antioxidant potential, and antimicrobial activity of mango seed kernel extracts

(2016) Jane K. Mutua et al.   Food Science & Nutrition

Role of Metabolic Enzymes P450 (CYP) on Activating Procarcinogen and their Polymorphisms on the Risk of Cancers

(2015) Xin He et al.   CURRENT DRUG METABOLISM

Comparative Assessment of Phenolic Content and in Vitro Antioxidant Capacity in the Pulp and Peel of Mango Cultivars

(2015) Arshad Abbasi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A breakthrough in probiotics: Clostridium butyricum regulates gut homeostasis and anti-inflammatory response in inflammatory bowel disease

(2015) Takanori Kanai et al.   JOURNAL OF GASTROENTEROLOGY

Cooperative Binding of Aflatoxin B1 by Cytochrome P450 3A4: A Computational Study

(2014) Urban Bren et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Analytical Methods for Determining Bioavailability and Bioaccessibility of Bioactive Compounds from Fruits and Vegetables: A Review

(2014) Juana M. Carbonell-Capella et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Sicilian pistachio (Pistacia vera L.) nut inhibits expression and release of inflammatory mediators and reverts the increase of paracellular permeability in IL-1β-exposed human intestinal epithelial cells

(2014) C. Gentile et al.   EUROPEAN JOURNAL OF NUTRITION

Protective effects of gallic acid against chronic cerebral hypoperfusion-induced cognitive deficit and brain oxidative damage in rats

(2014) Mehrdad Shahrani Korani et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mangiferin attenuates the symptoms of dextran sulfate sodium-induced colitis in mice via NF-κB and MAPK signaling inactivation

(2014) Wei Dou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Phytochemical Composition and Effects of Commercial Enzymes on the Hydrolysis of Gallic Acid Glycosides in Mango (Mangifera indica L. cv. ‘Keitt’) Pulp

(2014) Kimberly A. Krenek et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Immunomodulatory Effect of a Wild Blueberry Anthocyanin-Rich Extract in Human Caco-2 Intestinal Cells

(2014) Valentina Taverniti et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Time-dependent inhibition of CYP3A4 by gallic acid in human liver microsomes and recombinant systems

(2014) Qiang-Hong Pu et al.   XENOBIOTICA

Bioactive compounds produced by gut microbial tannase: implications for colorectal cancer development

(2014) Félix López de Felipe et al.   Frontiers in Microbiology

The Central Role of the Gut Microbiota in Chronic Inflammatory Diseases

(2014) Caroline Marcantonio Ferreira et al.   Journal of Immunology Research

Uncovering the Lactobacillus plantarum WCFS1 Gallate Decarboxylase Involved in Tannin Degradation

(2013) N. Jimenez et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Antistaphylococcal and biofilm inhibitory activities of gallic, caffeic, and chlorogenic acids

(2013) Ângelo Luís et al.   BIOFOULING

A decrease of the butyrate-producing speciesRoseburia hominisandFaecalibacterium prausnitziidefines dysbiosis in patients with ulcerative colitis

(2013) Kathleen Machiels et al.   GUT

Benefits of polyphenols on gut microbiota and implications in human health

(2013) Fernando Cardona et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mexican ‘Ataulfo’ mango (Mangifera indica L) as a source of hydrolyzable tannins. Analysis by MALDI-TOF/TOF MS

(2012) Sonia G. Sáyago-Ayerdi et al.   FOOD RESEARCH INTERNATIONAL

Metabolism of Anthocyanins by Human Gut Microflora and Their Influence on Gut Bacterial Growth

(2012) Maria Hidalgo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Defining the human microbiome

(2012) Luke K Ursell et al.   NUTRITION REVIEWS

Mangifera indicaL. Extract and Mangiferin Modulate Cytochrome P450 and UDP-Glucuronosyltransferase Enzymes in Primary Cultures of Human Hepatocytes

(2012) Idania Rodeiro et al.   PHYTOTHERAPY RESEARCH

The function of our microbiota: who is out there and what do they do?

(2012) Noora Ottman et al.   Frontiers in Cellular and Infection Microbiology

Disproportionate Exposures in Environmental Justice and Other Populations: The Importance of Outliers

(2011) Michael Gochfeld et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Effects of quercetin on the bioavailability of doxorubicin in rats: Role of CYP3A4 and P-gp inhibition by quercetin

(2011) Jun-Shik Choi et al.   ARCHIVES OF PHARMACAL RESEARCH

Studies on collagen-tannic acid-collagenase ternary system: Inhibition of collagenase against collagenolytic degradation of extracellular matrix component of collagen

(2011) Ganesan Krishnamoorthy et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Anti-inflammatory and immunomodulatory efficacy of indigenous probiotic Lactobacillus plantarum Lp91 in colitis mouse model

(2011) Raj Kumar Duary et al.   MOLECULAR BIOLOGY REPORTS

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Precipitation of low molecular weight phenolic compounds of grape seeds cv. Carménère (Vitis vinifera L.) by whole saliva

(2010) Elías Obreque-Slier et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Anticarcinogenic Effects of Polyphenolics from Mango (Mangifera indica) Varieties

(2010) Giuliana D. Noratto et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cytochrome P450-mediated metabolism in the human gut wall

(2010) Kirstin Thelen et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Anti-inflammatory effects ofMangifera indicaL. extract in a model of colitis

(2010) Lucía Márquez   WORLD JOURNAL OF GASTROENTEROLOGY

Microbial diversity in the human intestine and novel insights from metagenomics

(2009) Marco Ventura   Frontiers in Bioscience-Landmark

Antimicrobial Activity of Gallotannins Isolated from Mango (Mangifera indica L.) Kernels

(2009) Christina Engels et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Major Mango Polyphenols and Their Potential Significance to Human Health

(2008) Martin Masibo et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Inhibition of human P450 enzymes by natural extracts used in traditional medicine

(2008) Idania Rodeiro et al.   PHYTOTHERAPY RESEARCH