Medicinal Plants with Anti-Leukemic Effects: A Review

Development and characterization of a novel flavopiridol formulation for treatment of acute myeloid leukemia

(2021) Kent T.J. Chen et al.   JOURNAL OF CONTROLLED RELEASE

Therapeutic Efficacy of Nyctanthes arbor-tristis Flowers to Inhibit Proliferation of Acute and Chronic Primary Human Leukemia Cells, with Adipocyte Differentiation and in Silico Analysis of Interactions between Survivin Protein and Selected Secondary Metabolites

(2020) Saumya Nishanga Heendeniya et al.   Biomolecules

Xanthine Oxidase Inhibitory Activity, Chemical Composition, Antioxidant Properties and GC-MS Analysis of Keladi Candik (Alocasia longiloba Miq)

(2020) Ferid Abdulhafiz et al.   MOLECULES

Micropropagation of Alocasia longiloba Miq and Comparative Antioxidant Properties of Ethanolic Extracts of the Field-Grown Plant, In Vitro Propagated and In Vitro-Derived Callus

(2020) Ferid Abdulhafiz et al.   Plants-Basel

Ficus deltoidea: Effects of solvent polarity on antioxidant and anti-proliferative activities in breast and colon cancer cells

(2019) Mitra Abolmaesoomi et al.   European Journal of Integrative Medicine

Oxidative stress mediated cytotoxicity in leukemia cells induced by active phyto-constituents isolated from traditional herbal drugs of West Bengal

(2019) Monaj Kumar Sarkar et al.   JOURNAL OF ETHNOPHARMACOLOGY

Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead

(2018) Emanuela Martino et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antiproliferative activities and phenolic acid content of water and ethanolic extracts of the powdered formula of Houttuynia cordata Thunb. fermented broth and Phyllanthus emblica Linn. fruit

(2018) Piyawan Kumnerdkhonkaen et al.   BMC Complementary and Alternative Medicine

Chemical Constituents of Coreopsis lanceolata Stems and Their Antitermitic Activity Against the Subterranean Termite Coptotermes curvignathus

(2018) Antoni Pardede et al.   JOURNAL OF ECONOMIC ENTOMOLOGY

Viscum articulatum Burm. f. aqueous extract exerts antiproliferative effect and induces cell cycle arrest and apoptosis in leukemia cells

(2018) Ruchi Mishra et al.   JOURNAL OF ETHNOPHARMACOLOGY

IMGN779, a Novel CD33-Targeting Antibody–Drug Conjugate with DNA-Alkylating Activity, Exhibits Potent Antitumor Activity in Models of AML

(2018) Yelena Kovtun et al.   MOLECULAR CANCER THERAPEUTICS

Rapid and Simultaneous Determination of Three Active Components in Raw and Processed Root Samples of Scutellaria baicalensis by Near-infrared Spectroscopy

(2018) Xue Jintao et al.   PLANTA MEDICA

Infectious complications in adults undergoing intensive chemotherapy for acute myeloid leukemia in 2001–2005 using the Japan Adult Leukemia Study Group AML201 protocols

(2018) Hideaki Kato et al.   SUPPORTIVE CARE IN CANCER

Oxidative DNA Damage Is Prevented by Extracts of Olive Oil, Hydroxytyrosol, and Other Olive Phenolic Compounds in Human Blood Mononuclear Cells and HL60 Cells

(2018) Roberto Fabiani et al.   JOURNAL OF NUTRITION

In vitro mitochondria-mediated anticancer and antiproliferative effects of Annona glabra leaf extract against human leukemia cells

(2018) Ying Liu et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Berberine: Botanical Occurrence, Traditional Uses, Extraction Methods, and Relevance in Cardiovascular, Metabolic, Hepatic, and Renal Disorders

(2018) Maria A. Neag et al.   Frontiers in Pharmacology

In Vivo Anticancer Activity of Basella alba Leaf and Seed Extracts against Ehrlich's Ascites Carcinoma (EAC) Cell Line

(2018) Md. Shihabul Islam et al.   Evidence-based Complementary and Alternative Medicine

(+)-Isobicyclogermacrenal and spathulenol from Aristolochia yunnanensis alleviate cardiac fibrosis by inhibiting transforming growth factor β /small mother against decapentaplegic signaling pathway

(2018) Lan-Lan Lou et al.   PHYTOTHERAPY RESEARCH

A review of botany, phytochemical and pharmacological properties of Ferulago angulata

(2017) Zahra Lorigooini et al.   Toxin Reviews

Oral Mucositis in Pediatric Patients in Treatment for Acute Lymphoblastic Leukemia

(2017) Isabella Ribeiro et al.   International Journal of Environmental Research and Public Health

In Vitro Pro-apoptotic and Anti-migratory Effects of Ficus deltoidea L. Plant Extracts on the Human Prostate Cancer Cell Lines PC3

(2017) Mohd M. M. Hanafi et al.   Frontiers in Pharmacology

Flavonoid profile and antileukemic activity of Coreopsis lanceolata flowers

(2016) Antoni Pardede et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cell Cycle-Dependent Mechanisms Underlie Vincristine-Induced Death of Primary Acute Lymphoblastic Leukemia Cells

(2016) A. Kothari et al.   CANCER RESEARCH

A review: benefit and bioactive properties of olive (Olea europaea L.) leaves

(2016) Mehmet Musa Özcan et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Cancer Patients' Experiences of Using Mistletoe (Viscum album): A Qualitative Systematic Review and Synthesis

(2016) Maggie Evans et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

Natural product discovery: past, present, and future

(2016) Leonard Katz et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Polyphenols derived from four indigenous Indian fruits for cancer chemoprevention and chemotherapy

(2016) Biswas Majee Sutapa et al.   Journal of Medicinal Plants Research

A new cytotoxic diterpenoid glycoside from the leaves of Blumea lacera and its effects on apoptosis and cell cycle

(2016) Raushanara Akter et al.   NATURAL PRODUCT RESEARCH

Antioxidant and Anti-proliferative Activities of Flavonoids from Bidens pilosa L var radiata Sch Bip

(2016) Jun Yi et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Cross-species biosynthesis of maytansine in Maytenus serrata

(2016) Parijat Kusari et al.   RSC Advances

Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

(2015) Anuradha Thakur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Identification of phenolics in litchi and evaluation of anticancer cell proliferation activity and intracellular antioxidant activity

(2015) Lingrong Wen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Optimizing the extraction of anti-tumor alkaloids from the stem of Berberis amurensis by response surface methodology

(2015) Junkai Wu et al.   INDUSTRIAL CROPS AND PRODUCTS

Clinical activity of alvocidib (flavopiridol) in acute myeloid leukemia

(2015) Joshua F. Zeidner et al.   LEUKEMIA RESEARCH

Phytochemical profile and therapeutic potential ofViscum albumL.

(2015) Jolanta Nazaruk et al.   NATURAL PRODUCT RESEARCH

Chemical constituents of theAnnona glabrafruit and their cytotoxic activity

(2015) Nguyen Thi Thu Hien et al.   PHARMACEUTICAL BIOLOGY

The Effects of Herbs and Fruits on Leukaemia

(2014) Tayebeh Azam Saedi et al.   Evidence-based Complementary and Alternative Medicine

Baicalin from the extract of Scutellaria baicalensis affects the innate immunity and apoptosis in leukocytes of children with acute lymphocytic leukemia

(2014) B. Orzechowska et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Olive (Olea europaea) Leaf Extract Induces Apoptosis and Monocyte/Macrophage Differentiation in Human Chronic Myelogenous Leukemia K562 Cells: Insight into the Underlying Mechanism

(2014) Imen Samet et al.   Oxidative Medicine and Cellular Longevity

In VitroAntioxidant, Antiproliferative, and Phytochemical Study in Different Extracts ofNyctanthes arbortristisFlowers

(2014) Manjulatha Khanapur et al.   Biomed Research International

Bidens pilosaL. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology

(2013) Arlene P. Bartolome et al.   Evidence-based Complementary and Alternative Medicine

Synthesis of novel anticancer iridoid derivatives and their cell cycle arrest and caspase dependent apoptosis

(2013) Sukanya Pandeti et al.   PHYTOMEDICINE

Identification of flavonoids in litchi (Litchi chinensis Sonn.) leaf and evaluation of anticancer activities

(2013) Lingrong Wen et al.   Journal of Functional Foods

Houttuynia cordata Thunb Fraction Induces Human Leukemic Molt-4 Cell Apoptosis through the Endoplasmic Reticulum Stress Pathway

(2012) Adchara Prommaban et al.   Asian Pacific Journal of Cancer Prevention

Identification of a novel phenolic compound in litchi (Litchi chinensis Sonn.) pericarp and bioactivity evaluation

(2012) Guoxiang Jiang et al.   FOOD CHEMISTRY

Vitexin and isovitexin from the Leaves of Ficus deltoidea with in-vivo α-glucosidase inhibition

(2012) C.Y. Choo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia

(2011) Simona Lapusan et al.   INVESTIGATIONAL NEW DRUGS

Berbamine inhibits proliferation and induces apoptosis of KU812 cells by increasing Smad3 activity

(2011) Yun Liang et al.   Journal of Zhejiang University-SCIENCE B

The Antioxidant and Anti-proliferative Activity of the Lebanese Olea europaea Extract

(2011) Rida Fares et al.   PLANT FOODS FOR HUMAN NUTRITION

Potential of Plant-Derived Natural Products in the Treatment of Leukemia and Lymphoma

(2010) David M. Lucas et al.   CURRENT DRUG TARGETS

In VitroUltramorphological Assessment of Apoptosis on CEMss Induced by Linoleic Acid-Rich Fraction fromTyphonium flagelliformeTuber

(2010) Syam Mohan et al.   Evidence-based Complementary and Alternative Medicine

Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome c release: Its activation coupled with G0/G1 phase cell cycle arrest

(2010) Syam Mohan et al.   JOURNAL OF ETHNOPHARMACOLOGY

Typhonium flagelliforme inhibits the proliferation of murine leukemia WEHI-3 cells in vitro and induces apoptosis in vivo

(2010) Syam Mohan et al.   LEUKEMIA RESEARCH

Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules

(2010) M. Lopus et al.   MOLECULAR CANCER THERAPEUTICS

Inhibitory Effects of Rosemary Extracts, Carnosic Acid and Rosmarinic Acid on the Growth of Various Human Cancer Cell Lines

(2010) Ozlem Yesil-Celiktas et al.   PLANT FOODS FOR HUMAN NUTRITION

Berbamine exhibits potent antitumor effects on imatinib-resistant CML cells in vitro and in vivo

(2009) Yan-lin Wei et al.   ACTA PHARMACOLOGICA SINICA

Berbamine derivatives: A novel class of compounds for anti-leukemia activity

(2009) Jinwen Xie et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Immunomodulatory Activities of Various Medicinal Plant Extracts: Effects on Human Lymphocytes Apoptosis

(2009) Zahra Amirghofran et al.   IMMUNOLOGICAL INVESTIGATIONS

Phytochemicals in olive-leaf extracts and their antiproliferative activity against cancer and endothelial cells

(2009) Vlassios Goulas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Salvia Fruticosa, Salvia Officinalis,and Rosmarinic Acid Induce Apoptosis and Inhibit Proliferation of Human Colorectal Cell Lines: The Role in MAPK/ERK Pathway

(2009) Cristina P. R. Xavier et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells

(2009) Sheng-Teng Huang et al.   PHYTOMEDICINE

Bone mineral density in young adult survivors of acute lymphoblastic leukemia

(2008) Inas H. Thomas et al.   CANCER

Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro

(2008) Georg Seifert et al.   CANCER LETTERS

Typhonium flagelliforme inhibits cancer cell growth in vitro and induces apoptosis: An evaluation by the bioactivity guided approach

(2008) Choon-Sheen Lai et al.   JOURNAL OF ETHNOPHARMACOLOGY

In vitroAntitumor Mechanisms of VariousScutellariaExtracts and Constituent Flavonoids

(2008) Prahlad Parajuli et al.   PLANTA MEDICA