Bioanalytical Method Development and Validation Study of Neuroprotective Extract of Kashmiri Saffron Using Ultra-Fast Liquid Chromatography-Tandem Mass Spectrometry (UFLC-MS/MS): In Vivo Pharmacokinetics of Apocarotenoids and Carotenoids

Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway

(2021) Abubakar Wani et al.   Autophagy

Bioaccessibility and Pharmacokinetics of a Commercial Saffron (Crocus sativus L.) Extract

(2020) Paula Almodóvar et al.   Evidence-based Complementary and Alternative Medicine

Chemical analysis of saffron by HPLC based crocetin estimation

(2020) Chilakala Nagarjuna Reddy et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Nutraceutical Regulations: An Opportunities in ASEAN Countries

(2020) Chandani Tripathi et al.   NUTRITION

Isolation, purification and characterization of naturally derived Crocetin beta-d-glucosyl ester from Crocus sativus L. against breast cancer and its binding chemistry with ER-alpha/HDAC2

(2020) Mudasir A. Mir et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Bioactivity and Bioavailability of the Major Metabolites of Crocus sativus L. Flower

(2019) Moratalla-López et al.   MOLECULES

A novel UHPLC-HRMS-based metabolomics strategy enables the discovery of potential neuroactive metabolites in mice plasma, following i.p. administration of the main Crocus sativus L. bioactive component

(2019) Evangelia Karkoula et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Antioxidant Properties of Crocus Sativus L. and its Constituents and Relevance to Neurodegenerative Diseases; Focus on Alzheimer’s And Parkinson’s disease

(2018) Kyriaki Hatziagapiou et al.   Current Neuropharmacology

UHPLC Analysis of Saffron (Crocus sativus L.): Optimization of Separation Using Chemometrics and Detection of Minor Crocetin Esters

(2018) Angelo D’Archivio et al.   MOLECULES

Preparation, chemical characterization and determination of crocetin's pharmacokinetics after oral and intravenous administration of saffron (Crocus sativus L.) aqueous extract to C57/BL6J mice

(2018) Eirini Christodoulou et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Comparative evaluation of an ISO 3632 method and an HPLC-DAD method for safranal quantity determination in saffron

(2017) M. Valle García-Rodríguez et al.   FOOD CHEMISTRY

Saffron carotenoids (crocin and crocetin) binding to human serum albumin as investigated by different spectroscopic methods and molecular docking

(2017) Moslem Jafarisani et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Crocin Attenuates Kindling Development and Associated Cognitive Impairments in Mice via Inhibiting Reactive Oxygen Species-Mediated NF-κB Activation

(2016) Arindam Ghosh Mazumder et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Efficacy and Safety of Crocus sativus L. in Patients with Mild Cognitive Impairment: One Year Single-Blind Randomized, with Parallel Groups, Clinical Trial

(2016) Magda Tsolaki et al.   JOURNAL OF ALZHEIMERS DISEASE

Bioactive volatiles in Sicilian (South Italy) saffron: safranal and its related compounds

(2016) Concetta Condurso et al.   JOURNAL OF ESSENTIAL OIL RESEARCH

Neuropharmacological Aspects of Crocus sativus L.: A Review of Preclinical Studies and Ongoing Clinical Research

(2015) Damanpreet Singh   CNS & Neurological Disorders-Drug Targets

Sensory Threshold Studies of Picrocrocin, the Major Bitter Compound of Saffron

(2015) Andreas Chrysanthou et al.   JOURNAL OF FOOD SCIENCE

Simultaneous quantification of crocetin esters and picrocrocin changes in Chinese saffron by high-performance liquid chromatography-diode array detector during 15 years of storage

(2015) Ping Wang et al.   Pharmacognosy Magazine

Intestinal formation of trans-crocetin from saffron extract (Crocus sativus L.) and in vitro permeation through intestinal and blood brain barrier

(2015) M. Lautenschläger et al.   PHYTOMEDICINE

Safranal ofCrocus sativusL. Inhibits Inducible Nitric Oxide Synthase and Attenuates Asthma in a Mouse Model of Asthma

(2015) Syed Imran Bukhari et al.   PHYTOTHERAPY RESEARCH

The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety

(2014) Martins Ekor   Frontiers in Pharmacology

Avicenna's (Ibn Sina) the Canon of Medicine and Saffron (Crocus sativus): A Review

(2012) Hossein Hosseinzadeh et al.   PHYTOTHERAPY RESEARCH

Selective Th2 Upregulation byCrocus sativus: A Neutraceutical Spice

(2010) Sarang Bani et al.   Evidence-based Complementary and Alternative Medicine

Crocus sativus L. (saffron) attenuates isoproterenol-induced myocardial injury via preserving cardiac functions and strengthening antioxidant defense system

(2010) Jaspreet Sachdeva et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

The pharmacokinetic profile of crocetin in healthy adult human volunteers after a single oral administration

(2010) N. Umigai et al.   PHYTOMEDICINE

Picrocrocin Content and Quality Categories in Different (345) Worldwide Samples of Saffron (Crocus sativus L.)

(2009) C. Priscila del Campo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer’s disease

(2009) Shahin Akhondzadeh et al.   PSYCHOPHARMACOLOGY

Traditional medicinal plants of cold desert Ladakh—Used against kidney and urinary disorders

(2008) Basant Ballabh et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antioxidant potential of crocins and ethanol extracts of Gardenia jasminoides ELLIS and Crocus sativus L.: A relationship investigation between antioxidant activity and crocin contents

(2007) Yang Chen et al.   FOOD CHEMISTRY