Evaluation of Perylene Bisimide-Based RuIIand IrIIIComplexes as Photosensitizers for Photodynamic Therapy

Organometallic Rhenium Complexes Divert Doxorubicin to the Mitochondria

(2016) Sebastian Imstepf et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cellular Uptake and Photo-Cytotoxicity of a Gadolinium(III)-DOTA-Naphthalimide Complex “Clicked” to a Lipidated Tat Peptide

(2016) William O’Malley et al.   MOLECULES

A ruthenium(ii) based photosensitizer and transferrin complexes enhance photo-physical properties, cell uptake, and photodynamic therapy safety and efficacy

(2016) Pavel Kaspler et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Noncovalent Ruthenium(II) Complexes–Single-Walled Carbon Nanotube Composites for Bimodal Photothermal and Photodynamic Therapy with Near-Infrared Irradiation

(2015) Pingyu Zhang et al.   ACS Applied Materials & Interfaces

Highly Charged Ruthenium(II) Polypyridyl Complexes as Lysosome-Localized Photosensitizers for Two-Photon Photodynamic Therapy

(2015) Huaiyi Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphorescent iridium(III)-bis-N-heterocyclic carbene complexes as mitochondria-targeted theranostic and photodynamic anticancer agents

(2015) Yi Li et al.   BIOMATERIALS

Cobalt(III) Chaperone Complexes of Curcumin: Photoreduction, Cellular Accumulation and Light-Selective Toxicity towards Tumour Cells

(2015) Anna K. Renfrew et al.   CHEMISTRY-A EUROPEAN JOURNAL

Lightening up Ruthenium Complexes to Fight Cancer?

(2015) Cristina Mari et al.   CHIMIA

Control and utilization of ruthenium and rhodium metal complex excited states for photoactivated cancer therapy

(2015) Jessica D. Knoll et al.   COORDINATION CHEMISTRY REVIEWS

Synthesis, characterization and biological evaluation of mixed-ligand ruthenium(ii) complexes for photodynamic therapy

(2015) Huaiyi Huang et al.   DALTON TRANSACTIONS

Towards Selective Light-Activated RuII-Based Prodrug Candidates

(2015) Cristina Mari et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

A Luminescent Poly(amidoamine)–Iridium Complex as a New Singlet-Oxygen Sensitizer for Photodynamic Therapy

(2015) Daniela Maggioni et al.   INORGANIC CHEMISTRY

Drug Carrier for Photodynamic Cancer Therapy

(2015) Tilahun Debele et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A novel class of ruthenium-based photosensitizers effectively kills in vitro cancer cells and in vivo tumors

(2015) Jamie Fong et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

An iridium(iii)-based irreversible protein–protein interaction inhibitor of BRD4 as a potent anticancer agent

(2015) Hai-Jing Zhong et al.   Chemical Science

Cyclometalated iridium(iii) complexes as lysosome-targeted photodynamic anticancer and real-time tracking agents

(2015) Liang He et al.   Chemical Science

Combination of Ru(ii) complexes and light: new frontiers in cancer therapy

(2015) Cristina Mari et al.   Chemical Science

Organoiridium Complexes: Anticancer Agents and Catalysts

(2014) Zhe Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Group 9 Organometallic Compounds for Therapeutic and Bioanalytical Applications

(2014) Dik-Lung Ma et al.   ACCOUNTS OF CHEMICAL RESEARCH

Underestimated Potential of Organometallic Rhenium Complexes as Anticancer Agents

(2014) Anna Leonidova et al.   ACS Chemical Biology

Near-IR Phosphorescent Ruthenium(II) and Iridium(III) Perylene Bisimide Metal Complexes

(2014) Marcus Schulze et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Bis(dipyridophenazine)(2-(2-pyridyl)pyrimidine-4-carboxylic acid)ruthenium(II) Complex with Anticancer Action upon Photodeprotection

(2014) Tanmaya Joshi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Comparison Between Polypyridyl and Cyclometalated Ruthenium(II) Complexes: Anticancer Activities Against 2D and 3D Cancer Models

(2014) Huaiyi Huang et al.   CHEMISTRY-A EUROPEAN JOURNAL

DNA Intercalating RuIIPolypyridyl Complexes as Effective Photosensitizers in Photodynamic Therapy

(2014) Cristina Mari et al.   CHEMISTRY-A EUROPEAN JOURNAL

Shifting the Light Activation of Metallodrugs to the Red and Near-Infrared Region in Anticancer Phototherapy

(2014) Sylvestre Bonnet   COMMENTS ON INORGANIC CHEMISTRY

In Vitro Multiwavelength PDT with 3IL States: Teaching Old Molecules New Tricks

(2014) Huimin Yin et al.   INORGANIC CHEMISTRY

Targeted Singlet Oxygen Generation Using Different DNA-Interacting Perylene Diimide Type Photosensitizers

(2014) Haluk Dinçalp et al.   JOURNAL OF FLUORESCENCE

Synthesis, Characterization, and Biological Evaluation of New Ru(II) Polypyridyl Photosensitizers for Photodynamic Therapy

(2014) Angelo Frei et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting Nucleus DNA with a Cyclometalated Dipyridophenazineruthenium(II) Complex

(2014) Huaiyi Huang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Two in One: Luminescence Imaging and 730 nm Continuous Wave Laser Driven Photodynamic Therapy of Iridium Complexes

(2014) Fengfeng Xue et al.   ORGANOMETALLICS

In vivo anti-tumor activity of the organometallic ruthenium(ii)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) in human ovarian and colorectal carcinomas

(2014) Andrea Weiss et al.   Chemical Science

NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application

(2014) Robert Trondl et al.   Chemical Science

Enhanced Cytotoxicity through Conjugation of a “Clickable” Luminescent Re(I) Complex to a Cell-Penetrating Lipopeptide

(2014) Anna Leonidova et al.   ACS Medicinal Chemistry Letters

Mitochondria-targeting cyclometalated iridium(III)–PEG complexes with tunable photodynamic activity

(2013) Steve Po-Yam Li et al.   BIOMATERIALS

Exploration of the medical periodic table: towards new targets

(2013) Nicolas P. E. Barry et al.   CHEMICAL COMMUNICATIONS

Rhenium Complexes with Visible-Light-Induced Anticancer Activity

(2013) Anja Kastl et al.   ChemMedChem

Chiral ruthenium(ii) complexes with phenolic hydroxyl groups as dual poisons of topoisomerases I and IIα

(2013) Pingyu Zhang et al.   DALTON TRANSACTIONS

Towards cancer cell-specific phototoxic organometallic rhenium(i) complexes

(2013) Anna Leonidova et al.   DALTON TRANSACTIONS

Novel water-soluble 99mTc(I)/Re(I)-porphyrin conjugates as potential multimodal agents for molecular imaging

(2013) Cinzia Spagnul et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Cellular Toxicity Induced by the Photorelease of a Caged Bioactive Molecule: Design of a Potential Dual-Action Ru(II) Complex

(2013) Mark A. Sgambellone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New avenues in the design and potential application of metal complexes for photodynamic therapy

(2013) Oliver J. Stacey et al.   RSC Advances

Photodynamic Effect in Near-IR Light by a Photocytotoxic Iron(III) Cellular Imaging Agent

(2012) Uttara Basu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Designing Red-Light-Activated Multifunctional Agents for the Photodynamic Therapy

(2012) Samantha L. H. Higgins et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A novel ruthenium(ii)–cobaloxime supramolecular complex for photocatalytic H2 evolution: synthesis, characterisation and mechanistic studies

(2012) Donald M. Cropek et al.   DALTON TRANSACTIONS

Transition metal complexes meet the rylenes

(2012) Felix N. Castellano   DALTON TRANSACTIONS

Phenytoin reduces 5-aminolevulinic acid-induced protoporphyrin IX accumulation in malignant glioma cells

(2012) Martin Hefti et al.   JOURNAL OF NEURO-ONCOLOGY

Strained Ruthenium Complexes Are Potent Light-Activated Anticancer Agents

(2012) Brock S. Howerton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Towards the Preparation of Novel Re/99mTc Tricarbonyl-Containing Peptide Nucleic Acid Bioconjugates

(2011) Gilles Gasser et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Synthesis, characterisation and bioimaging of a fluorescent rhenium-containing PNA bioconjugate

(2011) Gilles Gasser et al.   DALTON TRANSACTIONS

Recent Exploitation of Luminescent Rhenium(I) Tricarbonyl Polypyridine Complexes as Biomolecular and Cellular Probes

(2011) Kenneth Kam-Wing Lo et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Approaching tumour therapy beyond platinum drugs

(2011) A. Bergamo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Organometallic Half-Sandwich Iridium Anticancer Complexes

(2011) Zhe Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Exceptional Intersystem Crossing in Di(perylene bisimide)s: A Structural Platform toward Photosensitizers for Singlet Oxygen Generation

(2010) Yishi Wu et al.   Journal of Physical Chemistry Letters

Susceptibility to 5-Aminolevulinic Acid Based Photodynamic Therapy in WHO I Meningioma Cells Corresponds to Ferrochelatase Activity

(2010) Martin Hefti et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Porphyrin and Nonporphyrin Photosensitizers in Oncology: Preclinical and Clinical Advances in Photodynamic Therapy

(2009) Aisling E. O’Connor et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients

(2008) Christian G. Hartinger et al.   CHEMISTRY & BIODIVERSITY

Cellular Uptake, Cytotoxicity, and Metabolic Profiling of Human Cancer Cells Treated with Ruthenium(II) Polypyridyl Complexes [Ru(bpy)2(NN)]Cl2with NN=bpy, phen, dpq, dppz, and dppn

(2008) Ulrich Schatzschneider et al.   ChemMedChem

Photophysics and photochemistry of photodynamic therapy: fundamental aspects

(2008) K. Plaetzer et al.   LASERS IN MEDICAL SCIENCE