Combination of Ru(ii) complexes and light: new frontiers in cancer therapy
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Title
Combination of Ru(ii) complexes and light: new frontiers in cancer therapy
Authors
Keywords
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Journal
Chemical Science
Volume 6, Issue 5, Pages 2660-2686
Publisher
Royal Society of Chemistry (RSC)
Online
2015-01-13
DOI
10.1039/c4sc03759f
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Note: Only part of the references are listed.- Towards Tris(diimine)–Ruthenium(II) and Bis(quinoline)–Re(I)(CO)3 Complexes as Photoactivated Anticancer Drug Candidates
- (2015) Tanmaya Joshi et al. SYNLETT
- A Bis(dipyridophenazine)(2-(2-pyridyl)pyrimidine-4-carboxylic acid)ruthenium(II) Complex with Anticancer Action upon Photodeprotection
- (2014) Tanmaya Joshi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- DNA Intercalating RuIIPolypyridyl Complexes as Effective Photosensitizers in Photodynamic Therapy
- (2014) Cristina Mari et al. CHEMISTRY-A EUROPEAN JOURNAL
- Bis(dipyridophenazine)(2-(2′-pyridyl)pyrimidine-4-carboxylic acid)ruthenium(II) Hexafluorophosphate: A Lesson in Stubbornness
- (2014) Tanmaya Joshi et al. ChemMedChem
- Inhibition of Cathepsin Activity in a Cell-Based Assay by a Light-Activated Ruthenium Compound
- (2014) Tomasz Respondek et al. ChemMedChem
- Metal complexes as structural templates for targeting proteins
- (2014) Markus Dörr et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Fusion of photodynamic therapy and photoactivated chemotherapy: a novel Ru(ii) arene complex with dual activities of photobinding and photocleavage toward DNA
- (2014) Yongjie Chen et al. DALTON TRANSACTIONS
- Toxicity and localization studies of a potential photodynamic therapy agent inDrosophila
- (2014) Joshua Yoho et al. GENESIS
- In Vitro Multiwavelength PDT with 3IL States: Teaching Old Molecules New Tricks
- (2014) Huimin Yin et al. INORGANIC CHEMISTRY
- Photoactive Ru(II) Complexes With Dioxinophenanthroline Ligands Are Potent Cytotoxic Agents
- (2014) Achmad N. Hidayatullah et al. INORGANIC CHEMISTRY
- Modifying Charge and Hydrophilicity of Simple Ru(II) Polypyridyl Complexes Radically Alters Biological Activities: Old Complexes, Surprising New Tricks
- (2014) Matthew Dickerson et al. INORGANIC CHEMISTRY
- Ruthenium Tris(2-pyridylmethyl)amine as an Effective Photocaging Group for Nitriles
- (2014) Rajgopal Sharma et al. INORGANIC CHEMISTRY
- Synthesis, Characterization, and Biological Evaluation of New Ru(II) Polypyridyl Photosensitizers for Photodynamic Therapy
- (2014) Angelo Frei et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cytotoxicity Studies of Cyclometallated Ruthenium(II) Compounds: New Applications for Ruthenium Dyes
- (2014) Bruno Peña et al. ORGANOMETALLICS
- In vivo anti-tumor activity of the organometallic ruthenium(ii)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) in human ovarian and colorectal carcinomas
- (2014) Andrea Weiss et al. Chemical Science
- NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application
- (2014) Robert Trondl et al. Chemical Science
- Two-Photon Optical Interrogation of Individual Dendritic Spines with Caged Dopamine
- (2013) Roberto Araya et al. ACS Chemical Neuroscience
- Diazido Mixed-Amine Platinum(IV) Anticancer Complexes Activatable by Visible-Light Form Novel DNA Adducts
- (2013) Yao Zhao et al. CHEMISTRY-A EUROPEAN JOURNAL
- Transferrin Serves As a Mediator to Deliver Organometallic Ruthenium(II) Anticancer Complexes into Cells
- (2013) Wei Guo et al. INORGANIC CHEMISTRY
- Light-Activated Metal Complexes that Covalently Modify DNA
- (2013) Edith C. Glazer ISRAEL JOURNAL OF CHEMISTRY
- Exploitation of Long-Lived 3IL Excited States for Metal–Organic Photodynamic Therapy: Verification in a Metastatic Melanoma Model
- (2013) Richard Lincoln et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cellular Toxicity Induced by the Photorelease of a Caged Bioactive Molecule: Design of a Potential Dual-Action Ru(II) Complex
- (2013) Mark A. Sgambellone et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cytotoxicity of cyclometallated ruthenium complexes: the role of ligand exchange on the activity
- (2013) A. M. Palmer et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
- Photoactivatable metal complexes: from theory to applications in biotechnology and medicine
- (2013) N. A. Smith et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
- RuBiGABA-2: a hydrophilic caged GABA with long wavelength sensitivity
- (2013) Oscar Filevich et al. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
- New cyclometallated Ru(ii) complex for potential application in photochemotherapy?
- (2013) Bryan A. Albani et al. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
- Photodynamic inactivation of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus with Ru(II)-based type I/type II photosensitizers
- (2013) Yaxal Arenas et al. Photodiagnosis and Photodynamic Therapy
- New avenues in the design and potential application of metal complexes for photodynamic therapy
- (2013) Oliver J. Stacey et al. RSC Advances
- Designing Red-Light-Activated Multifunctional Agents for the Photodynamic Therapy
- (2012) Samantha L. H. Higgins et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Sixty Years Young: The Diverse Biological Activities of Metal Polypyridyl Complexes Pioneered by Francis P. Dwyer
- (2012) Nathan L. Kilah et al. AUSTRALIAN JOURNAL OF CHEMISTRY
- Comparative Studies of the Cellular Uptake, Subcellular Localization, and Cytotoxic and Phototoxic Antitumor Properties of Ruthenium(II)–Porphyrin Conjugates with Different Linkers
- (2012) Jing-Xiang Zhang et al. BIOCONJUGATE CHEMISTRY
- Rapid Development of a Potent Photo-triggered Inhibitor of the Serine Hydrolase RBBP9
- (2012) Xiaodan Liu et al. CHEMBIOCHEM
- Light-activated ruthenium complexes photobind DNA and are cytotoxic in the photodynamic therapy window
- (2012) Erin Wachter et al. CHEMICAL COMMUNICATIONS
- What Does the Future Hold for Photo-Oxidizing RuII Complexes with Polyazaaromatic Ligands in Medicinal Chemistry?
- (2012) Jonathan Ghesquiere et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Nickel, copper, and zinc centered ruthenium-substituted porphyrins: effect of transition metals on photoinduced DNA cleavage and photoinduced melanoma cell toxicity
- (2012) Patrick Sweigert et al. DALTON TRANSACTIONS
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- (2012) A Reschner et al. GENE THERAPY
- Systems biology approach for in vivo photodynamic therapy optimization of ruthenium-porphyrin compounds
- (2012) Marlène Pernot et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
- Mesoscale DNA Structural Changes on Binding and Photoreaction with Ru[(TAP)2PHEHAT]2+
- (2012) Willem Vanderlinden et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Strained Ruthenium Complexes Are Potent Light-Activated Anticancer Agents
- (2012) Brock S. Howerton et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Molecular and Cellular Characterization of the Biological Effects of Ruthenium(II) Complexes Incorporating 2-Pyridyl-2-pyrimidine-4-carboxylic Acid
- (2012) Vanessa Pierroz et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: A Light-Activated Antitumor Platinum Complex That Kills Human Cancer Cells by an Apoptosis-Independent Mechanism
- (2012) A. F. Westendorf et al. MOLECULAR CANCER THERAPEUTICS
- Efficient photodynamic therapy of cancer using chemotherapeutic porphyrin–ruthenium metalla-cubes
- (2011) Frédéric Schmitt et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- In vivo photorelease of GABA in the mouse cortex
- (2011) V. Lopes-dos-Santos et al. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Targeted and multifunctional arene ruthenium chemotherapeutics
- (2011) Gregory S. Smith et al. DALTON TRANSACTIONS
- Polypyridyl Metal Complexes with Biological Activity
- (2011) Luca Salassa EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
- Approaching tumour therapy beyond platinum drugs
- (2011) A. Bergamo et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Organometallic Cages as Vehicles for Intracellular Release of Photosensitizers
- (2011) Frédéric Schmitt et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Photocontrolled DNA Binding of a Receptor-Targeted Organometallic Ruthenium(II) Complex
- (2011) Flavia Barragán et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Efficient DNA photocleavage by [Ru(bpy)2(dppn)]2+ with visible light
- (2010) Yujie Sun et al. CHEMICAL COMMUNICATIONS
- Contributions to the development of ruthenium-based sensitizers for dye-sensitized solar cells
- (2010) Georgios C. Vougioukalakis et al. COORDINATION CHEMISTRY REVIEWS
- Photo-reactive RuII-oligonucleotide conjugates: influence of an intercalating ligand on the inter- and intra-strand photo-ligation processes
- (2010) Stéphane Le Gac et al. DALTON TRANSACTIONS
- Photoactivated Biological Activity of Transition-Metal Complexes
- (2010) Ulrich Schatzschneider EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
- A caged nicotine with nanosecond range kinetics and visible light sensitivity
- (2010) Oscar Filevich et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Ruthenium−Porphyrin Conjugates with Cytotoxic and Phototoxic Antitumor Activity
- (2010) Teresa Gianferrara et al. JOURNAL OF MEDICINAL CHEMISTRY
- Organometallic ruthenium-based antitumor compounds with novel modes of action
- (2010) Wee Han Ang et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates
- (2010) Jiyong Lee et al. Nature Chemical Biology
- Photoactivated chemotherapy (PACT): the potential of excited-state d-block metals in medicine
- (2009) Nicola J. Farrer et al. DALTON TRANSACTIONS
- Nuclear targets of photodynamic tridentate ruthenium complexes
- (2009) Ran Zhao et al. DALTON TRANSACTIONS
- Synthetic strategies towards ruthenium–porphyrin conjugates for anticancer activity
- (2009) Teresa Gianferrara et al. DALTON TRANSACTIONS
- On the Viability of Cyclometalated Ru(II) Complexes for Light-Harvesting Applications
- (2009) Paolo G. Bomben et al. INORGANIC CHEMISTRY
- A ruthenium(II) polypyridyl complex for direct imaging of DNA structure in living cells
- (2009) Martin R. Gill et al. Nature Chemistry
- RuBi-Glutamate: Two-photon and visible-light photoactivation of neurons and dendritic spines
- (2009) Elodie Fino Frontiers in Neural Circuits
- PCNA damage caused by antineoplastic drugs
- (2008) Soo In Bae et al. BIOCHEMICAL PHARMACOLOGY
- KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients
- (2008) Christian G. Hartinger et al. CHEMISTRY & BIODIVERSITY
- Cellular Uptake, Cytotoxicity, and Metabolic Profiling of Human Cancer Cells Treated with Ruthenium(II) Polypyridyl Complexes [Ru(bpy)2(NN)]Cl2with NN=bpy, phen, dpq, dppz, and dppn
- (2008) Ulrich Schatzschneider et al. ChemMedChem
- A Fluorinated Ruthenium Porphyrin as a Potential Photodynamic Therapy Agent: Synthesis, Characterization, DNA Binding, and Melanoma Cell Studies
- (2008) Sandya Rani-Beeram et al. INORGANIC CHEMISTRY
- Ru(II) Complexes of New Tridentate Ligands: Unexpected High Yield of Sensitized1O2
- (2008) Yao Liu et al. INORGANIC CHEMISTRY
- Combined arene ruthenium porphyrins as chemotherapeutics and photosensitizers for cancer therapy
- (2008) Frédéric Schmitt et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Half-sandwich RuII[9]aneS3 complexes structurally similar to antitumor-active organometallic piano-stool compounds: Preparation, structural characterization and in vitro cytotoxic activity
- (2008) Ioannis Bratsos et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Ruthenium Porphyrin Compounds for Photodynamic Therapy of Cancer
- (2008) Frédéric Schmitt et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes
- (2008) Jasna Maksimoska et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Photophysics and photochemistry of photodynamic therapy: fundamental aspects
- (2008) K. Plaetzer et al. LASERS IN MEDICAL SCIENCE
- Prodrugs: design and clinical applications
- (2008) Jarkko Rautio et al. NATURE REVIEWS DRUG DISCOVERY
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