Comparison Between Polypyridyl and Cyclometalated Ruthenium(II) Complexes: Anticancer Activities Against 2D and 3D Cancer Models

Cytotoxicity Studies of Cyclometallated Ruthenium(II) Compounds: New Applications for Ruthenium Dyes

(2014) Bruno Peña et al.   ORGANOMETALLICS

Phosphorescent iridium(III) complexes as multicolor probes for specific mitochondrial imaging and tracking

(2013) Yu Chen et al.   BIOMATERIALS

Differential effects of cell adhesion, modulus and VEGFR-2 inhibition on capillary network formation in synthetic hydrogel arrays

(2013) Eric H. Nguyen et al.   BIOMATERIALS

Chiral ruthenium(ii) complexes with phenolic hydroxyl groups as dual poisons of topoisomerases I and IIα

(2013) Pingyu Zhang et al.   DALTON TRANSACTIONS

Studies on the interactions of bioactive quinone avarone and its methylamino derivatives with calf thymus DNA

(2013) Miroslava T. Vujčić et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Dual topoisomerase I and II poisoning by chiral Ru(II) complexes containing 2-thiophenylimidazo[4,5-f][1,10]phenanthroline derivatives

(2013) Yu-Chuan Wang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The induction of mitochondria-mediated apoptosis in cancer cells by ruthenium(ii) asymmetric complexes

(2013) Chen Qian et al.   Metallomics

Single-chromosome transcriptional profiling reveals chromosomal gene expression regulation

(2013) Marshall J Levesque et al.   NATURE METHODS

A dinuclear iridium(iii) complex as a visual specific phosphorescent probe for endogenous sulphite and bisulphite in living cells

(2013) Guanying Li et al.   Chemical Science

Induction of caspase 8 and reactive oxygen species by ruthenium-derived anticancer compounds with improved water solubility and cytotoxicity

(2012) Vania Vidimar et al.   BIOCHEMICAL PHARMACOLOGY

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Targeting and delivery of platinum-based anticancer drugs

(2012) Xiaoyong Wang et al.   CHEMICAL SOCIETY REVIEWS

Dual Targeting of Hypoxic and Acidic Tumor Environments with a Cobalt(III) Chaperone Complex

(2012) Natsuho Yamamoto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Excited State Dynamics of Two New Ru(II) Cyclometallated Dyes: Relation to Cells for Solar Energy Conversion and Comparison to Conventional Systems

(2012) Bruno Peña et al.   Journal of Physical Chemistry C

Strained Ruthenium Complexes Are Potent Light-Activated Anticancer Agents

(2012) Brock S. Howerton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular and Cellular Characterization of the Biological Effects of Ruthenium(II) Complexes Incorporating 2-Pyridyl-2-pyrimidine-4-carboxylic Acid

(2012) Vanessa Pierroz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Getting to the core of platinum drug bio-distributions: the penetration of anti-cancer platinum complexes into spheroid tumour models

(2012) Jenny Z. Zhang et al.   Metallomics

Osmium(vi) nitrido complexes bearing azole heterocycles: a new class of antitumor agents

(2012) Wen-Xiu Ni et al.   Chemical Science

Library of second-generation cycloruthenated compounds and evaluation of their biological properties as potential anticancer drugs: Passing the nanomolar barrier

(2011) Ludivine Fetzer et al.   DALTON TRANSACTIONS

Synthesis, DNA-binding and topoisomerase inhibitory activity of ruthenium(II) polypyridyl complexes

(2011) Ke-Jie Du et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Chiral ruthenium(II) anthraquinone complexes as dual inhibitors of topoisomerases I and II

(2011) Jun-Feng Kou et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

A Nonemissive Iridium(III) Complex That Specifically Lights-Up the Nuclei of Living Cells

(2011) Chunyan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Morphological and cytoskeletal changes of pancreatic cancer cells in three-dimensional spheroidal culture

(2011) Yoko Matsuda et al.   Medical Molecular Morphology

High drug attrition rates—where are we going wrong?

(2011) Lisa Hutchinson et al.   Nature Reviews Clinical Oncology

Lipophilic ruthenium complexes with tuned cell membrane affinity and photoactivated uptake

(2010) Frida R. Svensson et al.   BIOPHYSICAL CHEMISTRY

Droplet-based microfluidic system for multicellular tumor spheroid formation and anticancer drug testing

(2010) Linfen Yu et al.   LAB ON A CHIP

Microarrays for the scalable production of metabolically relevant tumour spheroids: a tool for modulating chemosensitivity traits

(2010) Heike Hardelauf et al.   LAB ON A CHIP

A Ruthenium-Containing Organometallic Compound Reduces Tumor Growth through Induction of the Endoplasmic Reticulum Stress Gene CHOP

(2009) Xiangjun Meng et al.   CANCER RESEARCH

In Vitro Transcription Inhibition by Ruthenium(II) Polypyridyl Complexes with Electropositive Ancillary Ligands

(2009) Feng Gao et al.   INORGANIC CHEMISTRY

Photophysical Properties and Singlet Oxygen Production by Ruthenium(II) Complexes of Benzo[i]dipyrido[3,2-a:2′,3′-c]phenazine: Spectroscopic and TD-DFT Study

(2009) Simon P. Foxon et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

Identification of Gastric Cancer Stem Cells Using the Cell Surface Marker CD44

(2009) Shigeo Takaishi et al.   STEM CELLS

Mechanism of Cellular Uptake of a Ruthenium Polypyridyl Complex†

(2008) Cindy A. Puckett et al.   BIOCHEMISTRY

Bioorganometallic chemistry—from teaching paradigms to medicinal applications

(2008) Christian G. Hartinger et al.   CHEMICAL SOCIETY REVIEWS

New trends for metal complexes with anticancer activity

(2008) Pieter CA Bruijnincx et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?

(2008) Giovanna Mazzoleni et al.   Genes and Nutrition

3-D Tumor Model forIn VitroEvaluation of Anticancer Drugs

(2008) Jayme L. Horning et al.   MOLECULAR PHARMACEUTICS

A chemical method for fast and sensitive detection of DNA synthesis in vivo

(2008) A. Salic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA