Microbiota-mediated protection against antibiotic-resistant pathogens

Development of the Microbiota and Associations With Birth Mode, Diet, and Atopic Disorders in a Longitudinal Analysis of Stool Samples, Collected From Infancy Through Early Childhood

(2020) Gianluca Galazzo et al.   GASTROENTEROLOGY

Cell envelope defects of different capsule‐null mutants in K1 hypervirulent Klebsiella pneumoniae can affect bacterial pathogenesis

(2020) Yi Han Tan et al.   MOLECULAR MICROBIOLOGY

Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota

(2020) Hiroko Nagao-Kitamoto et al.   NATURE MEDICINE

Commensal Bacteroidetes protect against Klebsiella pneumoniae colonization and transmission through IL-36 signalling

(2020) Richard P. Sequeira et al.   Nature Microbiology

Dietary Xanthan Gum Alters Antibiotic Efficacy against the Murine Gut Microbiota and Attenuates Clostridioides difficile Colonization

(2020) Matthew K. Schnizlein et al.   mSphere

A High-Fat/High-Protein, Atkins-Type Diet Exacerbates Clostridioides (Clostridium) difficile Infection in Mice, whereas a High-Carbohydrate Diet Protects

(2020) Chrisabelle C. Mefferd et al.   mSystems

Vancomycin exposure caused opportunistic pathogens bloom in intestinal microbiome by simulator of the human intestinal microbial ecosystem (SHIME)

(2020) Lei Liu et al.   ENVIRONMENTAL POLLUTION

Bacteria-Induced Group 2 Innate Lymphoid Cells in the Stomach Provide Immune Protection through Induction of IgA

(2020) Naoko Satoh-Takayama et al.   IMMUNITY

Microbial–host molecular exchange and its functional consequences in early mammalian life

(2020) Stephanie C. Ganal-Vonarburg et al.   SCIENCE

Gut microbial metabolites as multi-kingdom intermediates

(2020) Kimberly A. Krautkramer et al.   NATURE REVIEWS MICROBIOLOGY

Fecal Microbiota Transplantation is Superior to Fidaxomicin for Treatment of Recurrent Clostridium difficile Infection

(2019) Christian Lodberg Hvas et al.   GASTROENTEROLOGY

The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages

(2019) Julie Schulthess et al.   IMMUNITY

Microbial bile salt hydrolases mediate the efficacy of faecal microbiota transplant in the treatment of recurrent Clostridioides difficile infection

(2019) Benjamin H Mullish et al.   GUT

Dietary therapy for clostridium difficile colonization: A case series

(2019) David L. Suskind et al.   ANAEROBE

Pathogenicity of Enterococci

(2019) Elizabeth Fiore et al.   Microbiology Spectrum

Microbiota-derived lantibiotic restores resistance against vancomycin-resistant Enterococcus

(2019) Sohn G. Kim et al.   NATURE

Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth

(2019) Yan Shao et al.   NATURE

Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives

(2019) J. E. Choby et al.   JOURNAL OF INTERNAL MEDICINE

The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease

(2018) Kassem Makki et al.   Cell Host & Microbe

Mother-to-Infant Microbial Transmission from Different Body Sites Shapes the Developing Infant Gut Microbiome

(2018) Pamela Ferretti et al.   Cell Host & Microbe

Type 3 regulatory T cells at the interface of symbiosis

(2018) Joo-Hong Park et al.   JOURNAL OF MICROBIOLOGY

Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

(2018) Rebekah M. Martin et al.   Frontiers in Cellular and Infection Microbiology

Microbiota-accessible carbohydrates suppress Clostridium difficile infection in a murine model

(2018) Andrew J. Hryckowian et al.   Nature Microbiology

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

(2018) Niv Zmora et al.   CELL

Early-Life Formation of the Microbial and Immunological Environment of the Human Airways

(2018) Céline Pattaroni et al.   Cell Host & Microbe

Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification

(2018) Matthew T. Sorbara et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clostridioides difficile uses amino acids associated with gut microbial dysbiosis in a subset of patients with diarrhea

(2018) Eric J. Battaglioli et al.   Science Translational Medicine

The intestinal microbiota: Antibiotics, colonization resistance, and enteric pathogens

(2017) Sohn Kim et al.   IMMUNOLOGICAL REVIEWS

Carbapenem-resistant Enterobacteriaceae in patients admitted to the emergency department: prevalence, risk factors, and acquisition rate

(2017) M.C. Salomão et al.   JOURNAL OF HOSPITAL INFECTION

Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis

(2017) Wei Jia et al.   Nature Reviews Gastroenterology & Hepatology

The microbiota protects against respiratory infection via GM-CSF signaling

(2017) Rebecca L. Brown et al.   Nature Communications

Next-generation probiotics: the spectrum from probiotics to live biotherapeutics

(2017) Paul W. O’Toole et al.   Nature Microbiology

Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis

(2016) C. B. Hergott et al.   BLOOD

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

The regulation of host defences to infection by the microbiota

(2016) Rebecca L. Brown et al.   IMMUNOLOGY

Interactions between the microbiota and pathogenic bacteria in the gut

(2016) Andreas J. Bäumler et al.   NATURE

Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection

(2016) Joseph P Zackular et al.   NATURE MEDICINE

Clostridium difficile colitis: pathogenesis and host defence

(2016) Michael C. Abt et al.   NATURE REVIEWS MICROBIOLOGY

Resurrecting the intestinal microbiota to combat antibiotic-resistant pathogens

(2016) Eric G. Pamer   SCIENCE

How colonization by microbiota in early life shapes the immune system

(2016) Thomas Gensollen et al.   SCIENCE

Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population

(2016) I. Russel Lee et al.   Scientific Reports

Microbiota-Regulated IL-25 Increases Eosinophil Number to Provide Protection during Clostridium difficile Infection

(2016) Erica L. Buonomo et al.   Cell Reports

Cytokines IL-17 and IL-22 in the host response to infection

(2016) Maria Valeri et al.   Pathogens and Disease

Molecular Epidemiology of Colonizing and Infecting Isolates of Klebsiella pneumoniae

(2016) Rebekah M. Martin et al.   mSphere

An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses

(2015) Teruyuki Sano et al.   CELL

Innate Immune Defenses Mediated by Two ILC Subsets Are Critical for Protection against Acute Clostridium difficile Infection

(2015) Michael C. Abt et al.   Cell Host & Microbe

Rectal bacteriotherapy for recurrent Clostridium difficile-associated diarrhoea: results from a case series of 55 patients in Denmark 2000–2012

(2015) M. Tvede et al.   CLINICAL MICROBIOLOGY AND INFECTION

Commensal microbiota influence systemic autoimmune responses

(2015) J. T. Van Praet et al.   EMBO JOURNAL

Interleukin-22 and CD160 play additive roles in the host mucosal response toClostridium difficileinfection in mice

(2015) Amir A. Sadighi Akha et al.   IMMUNOLOGY

The Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae Colonization and Infection among Long-Term Acute Care Hospital Residents

(2015) John P Mills et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses

(2015) Darren Ruane et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gastrointestinal Tract Colonization Dynamics by DifferentEnterococcus faeciumClades

(2015) Maria Camila Montealegre et al.   JOURNAL OF INFECTIOUS DISEASES

Bacteriocin production augments niche competition by enterococci in the mammalian gastrointestinal tract

(2015) Sushma Kommineni et al.   NATURE

Complementarity and redundancy of IL-22-producing innate lymphoid cells

(2015) Lucille C Rankin et al.   NATURE IMMUNOLOGY

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

Burden of Clostridium difficile Infection in the United States

(2015) Fernanda C. Lessa et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clostridium difficile Infection

(2015) Daniel A. Leffler et al.   NEW ENGLAND JOURNAL OF MEDICINE

The role of the local microbial ecosystem in respiratory health and disease

(2015) Wouter A. A. de Steenhuijsen Piters et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Analysis of gene–environment interactions in postnatal development of the mammalian intestine

(2015) Seth Rakoff-Nahoum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The infant microbiome development: mom matters

(2015) Noel T. Mueller et al.   TRENDS IN MOLECULAR MEDICINE

Friend Turned Foe: Evolution of Enterococcal Virulence and Antibiotic Resistance

(2014) Daria Van Tyne et al.   Annual Review of Microbiology

Establishment of Intestinal Microbiota during Early Life: a Longitudinal, Explorative Study of a Large Cohort of Danish Infants

(2014) A. Bergstrom et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Epithelial IL-22RA1-Mediated Fucosylation Promotes Intestinal Colonization Resistance to an Opportunistic Pathogen

(2014) Tu Anh N. Pham et al.   Cell Host & Microbe

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile

(2014) Charlie G. Buffie et al.   NATURE

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice

(2014) Hitesh S Deshmukh et al.   NATURE MEDICINE

Multistate Point-Prevalence Survey of Health Care–Associated Infections

(2014) Shelley S. Magill et al.   NEW ENGLAND JOURNAL OF MEDICINE

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbiota-Dependent Crosstalk Between Macrophages and ILC3 Promotes Intestinal Homeostasis

(2014) A. Mortha et al.   SCIENCE

Microbial Programming of Systemic Innate Immunity and Resistance to Infection

(2014) Thomas B. Clarke   PLoS Pathogens

Meta-Analysis of Antibiotics and the Risk of Community-Associated Clostridium difficile Infection

(2013) Kevin A. Brown et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Microbiota signalling through MyD88 is necessary for a systemic neutrophilic inflammatory response

(2013) Dipti Karmarkar et al.   IMMUNOLOGY

Intestinal Microbiota Containing Barnesiella Species Cures Vancomycin-Resistant Enterococcus faecium Colonization

(2013) Carles Ubeda et al.   INFECTION AND IMMUNITY

Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis

(2013) Claudia Slimings et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Bioavailability of the anti-clostridial bacteriocin thuricin CD in gastrointestinal tract

(2013) M. C. Rea et al.   MICROBIOLOGY-SGM

Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria

(2013) Matthew R. Hepworth et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens

(2013) Katharine M. Ng et al.   NATURE

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nonredundant Function of Soluble LT 3 Produced by Innate Lymphoid Cells in Intestinal Homeostasis

(2013) A. A. Kruglov et al.   SCIENCE

The Microbiome in Infectious Disease and Inflammation

(2012) Kenya Honda et al.   Annual Review of Immunology

Novel screening assay for in vivo selection of Klebsiella pneumoniae genes promoting gastrointestinal colonisation

(2012) Erik J Boll et al.   BMC MICROBIOLOGY

Outer Membrane Vesicles of a Human Commensal Mediate Immune Regulation and Disease Protection

(2012) Yue Shen et al.   Cell Host & Microbe

Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity

(2012) Michael C. Abt et al.   IMMUNITY

Priming of Natural Killer Cells by Nonmucosal Mononuclear Phagocytes Requires Instructive Signals from Commensal Microbiota

(2012) Stephanie C. Ganal et al.   IMMUNITY

Critical Role for MyD88-Mediated Neutrophil Recruitment during Clostridium difficile Colitis

(2012) Irene Jarchum et al.   INFECTION AND IMMUNITY

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

(2012) Michael H. Shaw et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genomic variation landscape of the human gut microbiome

(2012) Siegfried Schloissnig et al.   NATURE

The human microbiome: at the interface of health and disease

(2012) Ilseung Cho et al.   NATURE REVIEWS GENETICS

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice

(2012) Trevor D. Lawley et al.   PLoS Pathogens

Inhibition of the NF-κB Pathway in Human Intestinal Epithelial Cells by Commensal Streptococcus salivarius

(2011) Ghalia Kaci et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Development of the Human Gastrointestinal Microbiota and Insights From High-Throughput Sequencing

(2011) Maria Gloria Dominguez-Bello et al.   GASTROENTEROLOGY

The influence of the microbiota on type-1 diabetes: on the threshold of a leap forward in our understanding

(2011) Diane Mathis et al.   IMMUNOLOGICAL REVIEWS

Nucleotide-Binding Oligomerization Domain 1 Mediates Recognition of Clostridium difficile and Induces Neutrophil Recruitment and Protection against the Pathogen

(2011) M. Hasegawa et al.   JOURNAL OF IMMUNOLOGY

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

(2011) Shinichiro Sawa et al.   NATURE IMMUNOLOGY

Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice

(2011) M. A. Kriegel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mammalian intestinal epithelium as integral player in the establishment and maintenance of host–microbial homeostasis

(2011) Claudia U. Duerr et al.   SEMINARS IN IMMUNOLOGY

A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins

(2011) Anthony Ryan et al.   PLoS Pathogens

miR-146a Mediates Protective Innate Immune Tolerance in the Neonate Intestine

(2010) Cécilia Chassin et al.   Cell Host & Microbe

Inhibiting the Initiation of Clostridium difficile Spore Germination using Analogs of Chenodeoxycholic Acid, a Bile Acid

(2010) J. A. Sorg et al.   JOURNAL OF BACTERIOLOGY

Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans

(2010) Carles Ubeda et al.   JOURNAL OF CLINICAL INVESTIGATION

Intestinal macrophages and response to microbial encroachment

(2010) P D Smith et al.   Mucosal Immunology

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Lactobacillus rhamnosus blocks inflammatory signaling in vivo via reactive oxygen species generation

(2009) Patricia W. Lin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites

(2009) Steven A. Saenz et al.   IMMUNOLOGICAL REVIEWS

Innate immunity

(2009) Stuart E. Turvey et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Carriage rate of carbapenem-resistant Klebsiella pneumoniae in hospitalised patients during a national outbreak

(2009) Y. Wiener-Well et al.   JOURNAL OF HOSPITAL INFECTION

In vivo equilibrium of proinflammatory IL-17+and regulatory IL-10+Foxp3+RORγt+T cells

(2008) Matthias Lochner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits

(2008) Katharina Brandl et al.   NATURE

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology