Sensing and Responding of Cardiomyocytes to Changes of Tissue Stiffness in the Diseased Heart
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Sensing and Responding of Cardiomyocytes to Changes of Tissue Stiffness in the Diseased Heart
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-02-26
DOI
10.3389/fcell.2021.642840
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair
- (2020) Filipa C. Simões et al. Nature Communications
- A cardiomyocyte show of force: A fluorescent alpha-actinin reporter line sheds light on human cardiomyocyte contractility versus substrate stiffness
- (2020) Marcelo C. Ribeiro et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Agrin Promotes Coordinated Therapeutic Processes Leading to Improved Cardiac Repair in Pigs
- (2020) Andrea Baehr et al. CIRCULATION
- Collagen, stiffness, and adhesion: the evolutionary basis of vertebrate mechanobiology
- (2020) Vivian W. Tang MOLECULAR BIOLOGY OF THE CELL
- Loss of Caveolin-1 and caveolae leads to increased cardiac cell stiffness and functional decline of the adult zebrafish heart
- (2020) Dimitrios Grivas et al. Scientific Reports
- Agrin-Mediated Cardiac Regeneration: Some Open Questions
- (2020) Maria Giulia Bigotti et al. Frontiers in Bioengineering and Biotechnology
- Microenvironment stiffness requires decellularized cardiac extracellular matrix to promote heart regeneration in the neonatal mouse heart
- (2020) Xinming Wang et al. Acta Biomaterialia
- Change the Laminin, Change the Cardiomyocyte: Improve Untreatable Heart Failure
- (2020) Camila Hochman-Mendez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mix and (mis-)match – The mechanosensing machinery in the changing environment of the developing, healthy adult and diseased heart
- (2019) Matthew Ward et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Cardiomyocytes facing fibrotic conditions re-express extracellular matrix transcripts
- (2019) Carlos O. Heras-Bautista et al. Acta Biomaterialia
- Material stiffness influences the polarization state, function and migration mode of macrophages
- (2019) Rukmani Sridharan et al. Acta Biomaterialia
- Cardiac fibrosis – A short review of causes and therapeutic strategies
- (2019) Svenja Hinderer et al. ADVANCED DRUG DELIVERY REVIEWS
- A Review of in vitro Platforms for Understanding Cardiomyocyte Mechanobiology
- (2019) Ian L. Chin et al. Frontiers in Bioengineering and Biotechnology
- Inhibition of Rho-associated kinases suppresses cardiac myofibroblast function in engineered connective and heart muscle tissues
- (2019) Gabriela Leão Santos et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Cardiomyocyte mechanodynamics under conditions of actin remodelling
- (2019) Ricardo H. Pires et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- The Giant Protein Titin’s Role in Cardiomyopathy: Genetic, Transcriptional, and Post-translational Modifications of TTN and Their Contribution to Cardiac Disease
- (2019) Charles A. Tharp et al. Frontiers in Physiology
- Desmin and Cardiac Disease
- (2018) Sonia R. Singh et al. CIRCULATION RESEARCH
- Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions
- (2018) Pragati Pandey et al. DEVELOPMENTAL CELL
- Cardiac macrophages promote diastolic dysfunction
- (2018) Maarten Hulsmans et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cardiac fibrosis: Cell biological mechanisms, molecular pathways and therapeutic opportunities
- (2018) Nikolaos G. Frangogiannis MOLECULAR ASPECTS OF MEDICINE
- The extracellular matrix in myocardial injury, repair, and remodeling
- (2017) Nikolaos G. Frangogiannis JOURNAL OF CLINICAL INVESTIGATION
- Effect of exercise on passive myocardial stiffness in mice with diastolic dysfunction
- (2017) Rebecca E. Slater et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The extracellular matrix protein agrin promotes heart regeneration in mice
- (2017) Elad Bassat et al. NATURE
- Multiscale force sensing in development
- (2017) Nicoletta I. Petridou et al. NATURE CELL BIOLOGY
- Role of titin in cardiomyopathy: from DNA variants to patient stratification
- (2017) James S. Ware et al. Nature Reviews Cardiology
- Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels
- (2017) William J. Hadden et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Agrin as a Mechanotransduction Signal Regulating YAP through the Hippo Pathway
- (2017) Sayan Chakraborty et al. Cell Reports
- Titin-Based Cardiac Myocyte Stiffening Contributes to Early Adaptive Ventricular Remodeling After Myocardial Infarction
- (2016) Sebastian Kötter et al. CIRCULATION RESEARCH
- Mechanisms of Hippo pathway regulation
- (2016) Zhipeng Meng et al. GENES & DEVELOPMENT
- Increases of desmin and α-actinin in mouse cardiac myofibrils as a response to diastolic dysfunction
- (2016) Juan-Juan Sheng et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Dystrophin-Deficient Cardiomyopathy
- (2016) Forum Kamdar et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity
- (2016) Alberto Elosegui-Artola et al. NATURE CELL BIOLOGY
- Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes
- (2016) P. Robison et al. SCIENCE
- Vinculin and Talin
- (2016) Alice Zemljic-Harpf et al. JOURNAL OF INVESTIGATIVE MEDICINE
- A role for matrix stiffness in the regulation of cardiac side population cell function
- (2015) Yiling Qiu et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Myocardial Stiffness in Patients With Heart Failure and a Preserved Ejection Fraction: Contributions of Collagen and Titin
- (2015) M. R. Zile et al. CIRCULATION
- Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration
- (2015) Jingli Cao et al. DEVELOPMENT
- Myocardin-related transcription factors are required for cardiac development and function
- (2015) Mayssa H. Mokalled et al. DEVELOPMENTAL BIOLOGY
- Hippo Pathway Effectors Control Cardiac Progenitor Cell Fate by Acting as Dynamic Sensors of Substrate Mechanics and Nanostructure
- (2014) Diogo Mosqueira et al. ACS Nano
- Role of nuclear Lamin A/C in cardiomyocyte functions
- (2014) Monica Carmosino et al. BIOLOGY OF THE CELL
- Myocardin-related transcription factors control the motility of epicardium-derived cells and the maturation of coronary vessels
- (2014) M. A. Trembley et al. DEVELOPMENT
- Appreciating force and shape — the rise of mechanotransduction in cell biology
- (2014) Thomas Iskratsch et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Differential changes in titin domain phosphorylation increase myofilament stiffness in failing human hearts
- (2013) Sebastian Kötter et al. CARDIOVASCULAR RESEARCH
- Heart-Specific Stiffening in Early Embryos Parallels Matrix and Myosin Expression to Optimize Beating
- (2013) Stephanie Majkut et al. CURRENT BIOLOGY
- Cardiac Titin and Heart Disease
- (2013) Martin M. LeWinter et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
- (2013) J. Swift et al. SCIENCE
- The constant beat: cardiomyocytes adapt their forces by equal contraction upon environmental stiffening
- (2013) N. Hersch et al. Biology Open
- Increased Passive Stiffness of Cardiomyocytes in the Transverse Direction and Residual Actin and Myosin Cross-Bridge Formation in Hypertrophied Rat Hearts Induced by Chronic ^|^beta;-Adrenergic Stimulation
- (2012) Wakako Sumita Yoshikawa et al. CIRCULATION JOURNAL
- Prevalence and Significance of Alterations in Cardiac Structure and Function in Patients With Heart Failure and a Preserved Ejection Fraction
- (2011) Michael R. Zile et al. CIRCULATION
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects
- (2010) Begoña López et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Passive Stiffness of Myocardium From Congenital Heart Disease and Implications for Diastole
- (2010) Rajiv R. Chaturvedi et al. CIRCULATION
- Myocardin-Related Transcription Factor A Is a Common Mediator of Mechanical Stress- and Neurohumoral Stimulation-Induced Cardiac Hypertrophic Signaling Leading to Activation of Brain Natriuretic Peptide Gene Expression
- (2010) K. Kuwahara et al. MOLECULAR AND CELLULAR BIOLOGY
- Influence of substrate stiffness on the phenotype of heart cells
- (2009) Bashir Bhana et al. BIOTECHNOLOGY AND BIOENGINEERING
- PKC Phosphorylation of Titin’s PEVK Element
- (2009) Carlos Hidalgo et al. CIRCULATION RESEARCH
- FAK signalling mediates NF-κB activation by mechanical stress in cardiac myocytes
- (2009) Daniella Pereira Crosara-Alberto et al. CLINICA CHIMICA ACTA
- Titin-based mechanical signalling in normal and failing myocardium
- (2009) Martina Krüger et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Substrate Stiffness Affects the Functional Maturation of Neonatal Rat Ventricular Myocytes
- (2008) Jeffrey G. Jacot et al. BIOPHYSICAL JOURNAL
- Protein Kinase G Modulates Human Myocardial Passive Stiffness by Phosphorylation of the Titin Springs
- (2008) Martina Krüger et al. CIRCULATION RESEARCH
- Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating
- (2008) A. J. Engler et al. JOURNAL OF CELL SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started