Chondrocyte ferroptosis contribute to the progression of osteoarthritis

The Application of Ferroptosis in Diseases

(2020) Yangmin Qiu et al.   PHARMACOLOGICAL RESEARCH

Regulation of stress signaling pathways by protein lipoxidation

(2019) Tommi Patinen et al.   Redox Biology

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways

(2019) Xudong Yao et al.   Frontiers in Pharmacology

Wnt16 attenuates osteoarthritis progression through a PCP/JNK-mTORC1-PTHrP cascade

(2019) Wenxue Tong et al.   ANNALS OF THE RHEUMATIC DISEASES

Association between the ABO blood group and primary knee osteoarthritis: A case–control study

(2019) Changchuan Li et al.   Journal of Orthopaedic Translation

Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis

(2019) Kai Sun et al.   Aging-US

Insight into the mechanism of ferroptosis inhibition by ferrostatin-1

(2019) Giovanni Miotto et al.   Redox Biology

Quercetin attenuates mitochondrial dysfunction and biogenesis via upregulated AMPK/SIRT1 signaling pathway in OA rats

(2018) Linan Qiu et al.   BIOMEDICINE & PHARMACOTHERAPY

NRF2 and the Hallmarks of Cancer

(2018) Montserrat Rojo de la Vega et al.   CANCER CELL

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Ligustrazine protects chondrocyte against IL-1β induced injury by regulation of SOX9/NF-κB signaling pathway

(2018) Tao Yu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration

(2018) Moataz Abdalkader et al.   Frontiers in Neuroscience

Role of GPX4 in ferroptosis and its pharmacological implication

(2018) Tobias M. Seibt et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fibroblast growth factor 18 exerts anti-osteoarthritic effects through PI3K-AKT signaling and mitochondrial fusion and fission

(2018) Xudong Yao et al.   PHARMACOLOGICAL RESEARCH

Interleukin-1β signaling in osteoarthritis – chondrocytes in focus

(2018) Zsuzsa Jenei-Lanzl et al.   CELLULAR SIGNALLING

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Spencer L James et al.   LANCET

An overview of the role of lipid peroxidation-derived 4-hydroxynonenal in osteoarthritis

(2017) Jamilah Abusarah et al.   INFLAMMATION RESEARCH

Hyperlipidaemia and incident osteoarthritis of the hand: a population-based case-control study

(2017) N. Frey et al.   OSTEOARTHRITIS AND CARTILAGE

Serum Lipid Levels and Risk Of Hand Osteoarthritis: The Chingford Prospective Cohort Study

(2017) M. Garcia-Gil et al.   Scientific Reports

Identification of ACSL4 as a biomarker and contributor of ferroptosis

(2016) Hua Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SOX9 and the many facets of its regulation in the chondrocyte lineage

(2016) Véronique Lefebvre et al.   CONNECTIVE TISSUE RESEARCH

Iron Homeostasis in Health and Disease

(2016) Raffaella Gozzelino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Iron overload in a murine model of hereditary hemochromatosis is associated with accelerated progression of osteoarthritis under mechanical stress

(2016) A. Camacho et al.   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression

(2015) Giuseppe Musumeci et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The detrimental effects of iron on the joint: a comparison between haemochromatosis and haemophilia

(2015) Lize F D van Vulpen et al.   JOURNAL OF CLINICAL PATHOLOGY

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Identification and expression of iron regulators in human synovium: evidence for upregulation in haemophilic arthropathy compared to rheumatoid arthritis, osteoarthritis, and healthy controls

(2013) L. Nieuwenhuizen et al.   HAEMOPHILIA

The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities

(2012) Jan Lewerenz et al.   ANTIOXIDANTS & REDOX SIGNALING

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Expression of the H- and L-subunits of ferritin in bone marrow macrophages of patients with osteoarthritis

(2012) Alida Maria Koorts et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Inflammation in osteoarthritis

(2011) Mary B. Goldring et al.   CURRENT OPINION IN RHEUMATOLOGY

Hereditary hemochromatosis is characterized by a clinically definable arthropathy that correlates with iron load

(2010) G. J. Carroll et al.   ARTHRITIS AND RHEUMATISM

The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis

(2010) Jérémie Sellam et al.   Nature Reviews Rheumatology