Reduced Expression of Autophagy Markers and Expansion of Myeloid-Derived Suppressor Cells Correlate With Poor T Cell Response in Severe COVID-19 Patients

Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection

(2020) Livan Delgado-Roche et al.   ARCHIVES OF MEDICAL RESEARCH

Convalescent plasma in Covid-19: Possible mechanisms of action

(2020) Manuel Rojas et al.   AUTOIMMUNITY REVIEWS

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

(2020) Alba Grifoni et al.   CELL

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

(2020) Evangelos J. Giamarellos-Bourboulis et al.   Cell Host & Microbe

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

(2020) Shuai Xia et al.   CELL RESEARCH

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

(2020) Meijuan Zheng et al.   Cellular & Molecular Immunology

Handling and Processing of Blood Specimens from Patients with COVID-19 for Safe Studies on Cell Phenotype and Cytokine Storm

(2020) Andrea Cossarizza et al.   CYTOMETRY PART A

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Tocilizumab treatment in COVID-19: A single center experience

(2020) Pan Luo et al.   JOURNAL OF MEDICAL VIROLOGY

Autophagy inhibition by chloroquine and hydroxychloroquine could adversely affect acute kidney injury and other organ injury in critically ill patients with COVID-19

(2020) Charles L. Edelstein et al.   KIDNEY INTERNATIONAL

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

Cytokine release syndrome in severe COVID-19

(2020) John B. Moore et al.   SCIENCE

Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues

(2020) Meng-Yuan Li et al.   Infectious Diseases of Poverty

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

(2020) Yonggang Zhou et al.   National Science Review

Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)

(2020) Chiara Agrati et al.   CELL DEATH AND DIFFERENTIATION

Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent

(2020) Alessio Mazzoni et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of biomarkers in diagnosis of COVID-19 – A systematic review

(2020) Muhammed Kermali et al.   LIFE SCIENCES

Convergent antibody responses to SARS-CoV-2 in convalescent individuals

(2020) Davide F. Robbiani et al.   NATURE

Single-cell landscape of immunological responses in patients with COVID-19

(2020) Ji-Yuan Zhang et al.   NATURE IMMUNOLOGY

The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2; COVID-19): A systematic review and meta-analysis of 148 studies from 9 countries

(2020) Michael C. Grant et al.   PLoS One

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

(2020) Divij Mathew et al.   SCIENCE

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

(2020) Philip J. M. Brouwer et al.   SCIENCE

Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

(2020) Jose Mateus et al.   SCIENCE

SARS-CoV-2 Dissemination Through Peripheral Nerves Explains Multiple Organ Injury

(2020) Matija Fenrich et al.   Frontiers in Cellular Neuroscience

Vitamin D for COVID-19: a case to answer?

(2020) Adrian R Martineau et al.   Lancet Diabetes & Endocrinology

Mild Cytokine Elevation, Moderate CD4+ T Cell Response and Abundant Antibody Production in Children with COVID-19

(2020) Ran Jia et al.   VIROLOGICA SINICA

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

(2020) Daniela Weiskopf et al.   Science Immunology

Neutrophil extracellular traps in COVID-19

(2020) Yu Zuo et al.   JCI Insight

The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics

(2020) Mitra Abbasifard et al.   LIFE SCIENCES

5-Fluorouracil in combination with deoxyribonucleosides and deoxyribose as possible therapeutic options for the Coronavirus, COVID-19 infection

(2020) Shamim I. Ahmad   MEDICAL HYPOTHESES

SARS-CoV-2 ORF3b Is a Potent Interferon Antagonist Whose Activity Is Increased by a Naturally Occurring Elongation Variant

(2020) Yoriyuki Konno et al.   Cell Reports

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

(2018) Mario Mauthe et al.   Autophagy

Autophagy in dendritic cells

(2018) Ghita Ghislat et al.   Cellular & Molecular Immunology

Autophagy and MHC-restricted antigen presentation

(2018) Jan Valečka et al.   MOLECULAR IMMUNOLOGY

Osteopontin plays a pivotal role in increasing severity of respiratory syncytial virus infection

(2018) Viviana Sampayo-Escobar et al.   PLoS One

The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging

(2018) Evgeny S. Egorov et al.   Frontiers in Immunology

Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells

(2018) Sergej Tomić et al.   International Journal of Nanomedicine

Modelling IRF8 Deficient Human Hematopoiesis and Dendritic Cell Development with Engineered iPS Cells

(2017) Stephanie Sontag et al.   STEM CELLS

Myeloid-Derived Suppressor Cells

(2017) Dmitry I. Gabrilovich   Cancer Immunology Research

Arginine Metabolism in Myeloid Cells Shapes Innate and Adaptive Immunity

(2017) Paulo C. Rodriguez et al.   Frontiers in Immunology

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

IL-6 down-regulates HLA class II expression and IL-12 production of human dendritic cells to impair activation of antigen-specific CD4+ T cells

(2016) Yosuke Ohno et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

Human Ebola virus infection results in substantial immune activation

(2015) Anita K. McElroy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IRF8 directs stress-induced autophagy in macrophages and promotes clearance of Listeria monocytogenes

(2015) Monica Gupta et al.   Nature Communications

IL-6-stimulated CD11b+ CD14+ HLA-DR− myeloid-derived suppressor cells, are associated with progression and poor prognosis in squamous cell carcinoma of the esophagus

(2015) Miao-Fen Chen et al.   Oncotarget

Autophagy Inhibition by Sustained Overproduction of IL6 Contributes to Arsenic Carcinogenesis

(2014) Y. Qi et al.   CANCER RESEARCH

CD141+ dendritic cells produce prominent amounts of IFN-  after dsRNA recognition and can be targeted via DEC-205 in humanized mice

(2013) S. Meixlsperger et al.   BLOOD

202

(2013) Beibei Qin et al.   CYTOKINE

IRF8 Is a Negative Regulator of Myeloid-Derived Suppressor Cells

(2013)   Cancer Discovery

ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activation

(2012) S. Weissmuller et al.   BLOOD

Rapid and Massive Virus-Specific Plasmablast Responses during Acute Dengue Virus Infection in Humans

(2012) J. Wrammert et al.   JOURNAL OF VIROLOGY

Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity

(2010) Suzanne Ostrand-Rosenberg   CANCER IMMUNOLOGY IMMUNOTHERAPY

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity

(2010) J. Vincent et al.   CANCER RESEARCH

Cellular Immune Responses to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection in Senescent BALB/c Mice: CD4+ T Cells Are Important in Control of SARS-CoV Infection

(2009) J. Chen et al.   JOURNAL OF VIROLOGY