Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

T cell responses induced by attenuated flavivirus vaccination are specific and show limited cross-reactivity with other flavivirus species

(2020) Alba Grifoni et al.   JOURNAL OF VIROLOGY

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

An interactive web-based dashboard to track COVID-19 in real time

(2020) Ensheng Dong et al.   LANCET INFECTIOUS DISEASES

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

(2020) Alba Grifoni et al.   CELL

Epidemiology of Seasonal Coronaviruses: Establishing the Context for the Emergence of Coronavirus Disease 2019

(2020) Sema Nickbakhsh et al.   JOURNAL OF INFECTIOUS DISEASES

A serological assay to detect SARS-CoV-2 seroconversion in humans

(2020) Fatima Amanat et al.   NATURE MEDICINE

Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19

(2020) Irani Thevarajan et al.   NATURE MEDICINE

A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV

(2020) Meng Yuan et al.   SCIENCE

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period

(2020) Stephen M. Kissler et al.   SCIENCE

COVID-19: an Immunopathological View

(2020) Kamran Kadkhoda   mSphere

Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients

(2020) Jing Liu et al.   EBioMedicine

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

(2020) Nina Le Bert et al.   NATURE

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

(2020) Divij Mathew et al.   SCIENCE

Broad neutralization of SARS-related viruses by human monoclonal antibodies

(2020) Anna Z. Wec et al.   SCIENCE

The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients

(2020) Lakshmanane Premkumar et al.   Science Immunology

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

(2020) Daniela Weiskopf et al.   Science Immunology

Human coronavirus circulation in the United States 2014–2017

(2018) Marie E. Killerby et al.   JOURNAL OF CLINICAL VIROLOGY

Original antigenic sin: A comprehensive review

(2017) Anup Vatti et al.   JOURNAL OF AUTOIMMUNITY

Global Assessment of Dengue Virus-Specific CD4+ T Cell Responses in Dengue-Endemic Areas

(2017) Alba Grifoni et al.   Frontiers in Immunology

Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4+ T Cell Responses

(2017) Ricardo da Silva Antunes et al.   PLoS One

Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells

(2017) Samantha Reiss et al.   PLoS One

Th1 versus Th2 T cell polarization by whole-cell and acellular childhood pertussis vaccines persists upon re-immunization in adolescence and adulthood

(2016) Tara Bancroft et al.   CELLULAR IMMUNOLOGY

Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with the allergen-specific modulation of immune reactivity

(2016) D. Hinz et al.   CLINICAL AND EXPERIMENTAL ALLERGY

A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+T Cells in Blood

(2016) Jennifer M. Dan et al.   JOURNAL OF IMMUNOLOGY

Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique

(2016) Colin Havenar-Daughton et al.   JOURNAL OF IMMUNOLOGY

HLA-DRB1 Alleles Are Associated With Different Magnitudes of Dengue Virus–Specific CD4+T-Cell Responses

(2016) Daniela Weiskopf et al.   JOURNAL OF INFECTIOUS DISEASES

A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans

(2016) Cecilia S. Lindestam Arlehamn et al.   PLoS Pathogens

Protective Role of Cross-Reactive CD8 T Cells Against Dengue Virus Infection

(2016) Annie Elong Ngono et al.   EBioMedicine

Definition of a pool of epitopes that recapitulates the T cell reactivity against major house dust mite allergens

(2015) D. Hinz et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Human CD8+T-Cell Responses Against the 4 Dengue Virus Serotypes Are Associated With Distinct Patterns of Protein Targets

(2015) Daniela Weiskopf et al.   JOURNAL OF INFECTIOUS DISEASES

Automatic Generation of Validated Specific Epitope Sets

(2015) Sebastian Carrasco Pro et al.   Journal of Immunology Research

Clinical Impact of Human Coronaviruses 229E and OC43 Infection in Diverse Adult Populations

(2013) E. E. Walsh et al.   JOURNAL OF INFECTIOUS DISEASES

Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes

(2011) Jason Greenbaum et al.   IMMUNOGENETICS

Prevalence of Antibodies to Four Human Coronaviruses Is Lower in Nasal Secretions than in Serum

(2010) G. J. Gorse et al.   Clinical and Vaccine Immunology

Molecular Determinants of T Cell Epitope Recognition to the Common Timothy Grass Allergen

(2010) C. Oseroff et al.   JOURNAL OF IMMUNOLOGY