Brilacidin Demonstrates Inhibition of SARS-CoV-2 in Cell Culture

Discovery and development of safe-in-man broad-spectrum antiviral agents

(2020) Petter I. Andersen et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Antimicrobial host defence peptides: functions and clinical potential

(2020) Neeloffer Mookherjee et al.   NATURE REVIEWS DRUG DISCOVERY

Computer-Aided Design of Antimicrobial Peptides: Are We Generating Effective Drug Candidates?

(2020) Marlon H. Cardoso et al.   Frontiers in Microbiology

Review of trials currently testing treatment and prevention of COVID-19

(2020) Paraskevi C. Fragkou et al.   CLINICAL MICROBIOLOGY AND INFECTION

Antimicrobial Peptides in Host Defense against Drug-Resistant Bacterial and Viral Infections

(2020) Yuanpu Peter Di   CURRENT MEDICINAL CHEMISTRY

Therapeutic and prophylactic potential of anti-microbial peptides against coronaviruses

(2020) Hamed Memariani et al.   IRISH JOURNAL OF MEDICAL SCIENCE

Rates of Co-infection Between SARS-CoV-2 and Other Respiratory Pathogens

(2020) David Kim et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Peptide-like and small-molecule inhibitors against Covid-19

(2020) Suyash Pant et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Blocking Coronavirus 19 Infection via the SARS-CoV-2 Spike Protein: Initial Steps

(2020) Jonathan Whisenant et al.   ACS Medicinal Chemistry Letters

Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths

(2020) William B. Grant et al.   Nutrients

The Current and Future State of Vaccines, Antivirals and Gene Therapies Against Emerging Coronaviruses

(2020) Longping V. Tse et al.   Frontiers in Microbiology

Protein- and Peptide-Based Virus Inactivators: Inactivating Viruses Before Their Entry Into Cells

(2020) Xiaojie Su et al.   Frontiers in Microbiology

Vitamin D Deficiency and Air Pollution Exacerbate COVID-19 Through Suppression of Antiviral Peptide LL37

(2020) Mardi A. Crane-Godreau et al.   Frontiers in Public Health

Evidence supporting the use of peptides and peptidomimetics as potential SARS-CoV-2 (COVID-19) therapeutics

(2020) Sonya VanPatten et al.   Future Medicinal Chemistry

Potential Anti-COVID-19 Therapeutics that Block the Early Stage of the Viral Life Cycle: Structures, Mechanisms, and Clinical Trials

(2020) Rami A. Al-Horani et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bacterial co-infections with SARS-CoV-2

(2020) Rasoul Mirzaei et al.   IUBMB LIFE

Inhibitors of SARS-CoV-2 Entry: Current and Future Opportunities

(2020) Siyu Xiu et al.   JOURNAL OF MEDICINAL CHEMISTRY

The value of antimicrobial peptides in the age of resistance

(2020) Maria Magana et al.   LANCET INFECTIOUS DISEASES

Longitudinal analyses reveal immunological misfiring in severe COVID-19

(2020) Carolina Lucas et al.   NATURE

Ongoing Clinical Trials for the Management of the COVID-19 Pandemic

(2020) Mark P. Lythgoe et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Molecular pathogenesis of secondary bacterial infection associated to viral infections including SARS-CoV-2

(2020) Sounik Manna et al.   Journal of Infection and Public Health

A New Era of Antibiotics: The Clinical Potential of Antimicrobial Peptides

(2020) Katrina Browne et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antiviral monotherapy for hospitalised patients with COVID-19 is not enough

(2020) Bin Cao et al.   LANCET

Covid-19, Ebola, and HIV — Leveraging Lessons to Maximize Impact

(2020) Connie Celum et al.   NEW ENGLAND JOURNAL OF MEDICINE

Will SARS-CoV-2 become endemic?

(2020) Jeffrey Shaman et al.   SCIENCE

Antimicrobial Peptides: Classification, Design, Application and Research Progress in Multiple Fields

(2020) Yuchen Huan et al.   Frontiers in Microbiology

The Potential of Antiviral Peptides as COVID-19 Therapeutics

(2020) Arun Suria Karnan Mahendran et al.   Frontiers in Pharmacology

Immunomodulatory Role of the Antimicrobial LL-37 Peptide in Autoimmune Diseases and Viral Infections

(2020) Bapi Pahar et al.   Vaccines

Integrative Network Biology Framework Elucidates Molecular Mechanisms of SARS-CoV-2 Pathogenesis

(2020) Nilesh Kumar et al.   iScience

Primed for global coronavirus pandemic: Emerging research and clinical outcome

(2020) Shakir Ahamad et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Peptides to combat viral infectious diseases

(2020) Shams Al-Azzam et al.   PEPTIDES

Reassessing the Host Defense Peptide Landscape

(2019) Evan F. Haney et al.   Frontiers in Chemistry

Antiviral peptides as promising therapeutic drugs

(2019) Liana Costa Pereira Vilas Boas et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Antimicrobial Peptide Database provides a platform for decoding the design principles of naturally occurring antimicrobial peptides

(2019) Guangshun Wang   PROTEIN SCIENCE

Human Antimicrobial Peptides as Therapeutics for Viral Infections

(2019) Aslaa Ahmed et al.   Viruses-Basel

Antiviral Activities of Human Host Defense Peptides

(2019) David C. Brice et al.   CURRENT MEDICINAL CHEMISTRY

FoldamerDB: a database of peptidic foldamers

(2019) Bilal Nizami et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of Action for Antimicrobial Peptides With Antibacterial and Antibiofilm Functions

(2019) Nigare Raheem et al.   Frontiers in Microbiology

Biomimetic antimicrobial polymers: recent advances in molecular design

(2018) Cansu Ergene et al.   Polymer Chemistry

Mining the tree of life: Host defense peptides as antiviral therapeutics

(2018) Jessica R. Shartouny et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Antiviral activity of cationic amphiphilic drugs

(2017) Cristiano Salata et al.   Expert Review of Anti-Infective Therapy

Mimics of Host Defense Proteins; Strategies for Translation to Therapeutic Applications

(2016) Richard W. Scott et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Therapeutic Potential of Foldamers: From Chemical Biology Tools To Drug Candidates?

(2016) Ranganath Gopalakrishnan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antiviral Mechanisms of Human Defensins

(2013) Sarah S. Wilson et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of Synthetic Host Defense Peptide Mimics That Exert Dual Antimicrobial and Anti-Inflammatory Activities

(2012) Abhigyan Som et al.   Clinical and Vaccine Immunology

Does Cholesterol Play a Role in the Bacterial Selectivity of Antimicrobial Peptides?

(2012) Jeffrey R. Brender et al.   Frontiers in Immunology

De Novo Design of Antimicrobial Polymers, Foldamers, and Small Molecules: From Discovery to Practical Applications

(2009) Gregory N. Tew et al.   ACCOUNTS OF CHEMICAL RESEARCH

Defensins in Viral Infections

(2009) Jian Ding et al.   Journal of Innate Immunity

De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers

(2009) S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo designed synthetic mimics of antimicrobial peptides

(2008) Richard W Scott et al.   CURRENT OPINION IN BIOTECHNOLOGY