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Title
White matter aging drives microglial diversity
Authors
Keywords
microglia, aging, white matter, myelin, ApoE, Trem2
Journal
NEURON
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-02-19
DOI
10.1016/j.neuron.2021.01.027
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Note: Only part of the references are listed.- Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease
- (2020) Yingyue Zhou et al. NATURE MEDICINE
- Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
- (2020) Julia Marschallinger et al. NATURE NEUROSCIENCE
- Preservation of a remote fear memory requires new myelin formation
- (2020) Simon Pan et al. NATURE NEUROSCIENCE
- Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory
- (2020) Fei Wang et al. NATURE NEUROSCIENCE
- Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion
- (2020) Jason R. Plemel et al. Science Advances
- Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer’s Disease
- (2020) Wei-Ting Chen et al. CELL
- Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis
- (2020) Yun Chen et al. NEURON
- Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution
- (2019) Takahiro Masuda et al. NATURE
- Single-cell transcriptomic analysis of Alzheimer’s disease
- (2019) Hansruedi Mathys et al. NATURE
- A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
- (2019) Hannah Van Hove et al. NATURE NEUROSCIENCE
- The Major Risk Factors for Alzheimer’s Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques
- (2019) Carlo Sala Frigerio et al. Cell Reports
- Central nervous system regeneration is driven by microglia necroptosis and repopulation
- (2019) Amy F. Lloyd et al. NATURE NEUROSCIENCE
- Myelin in the Central Nervous System: Structure, Function, and Pathology
- (2019) Christine Stadelmann et al. PHYSIOLOGICAL REVIEWS
- Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
- (2019) Yingyao Zhou et al. Nature Communications
- Single-cell transcriptomic profiling of the aging mouse brain
- (2019) Methodios Ximerakis et al. NATURE NEUROSCIENCE
- Microglia Biology: One Century of Evolving Concepts
- (2019) Marco Prinz et al. CELL
- Mapping microglia states in the human brain through the integration of high-dimensional techniques
- (2019) Roman Sankowski et al. NATURE NEUROSCIENCE
- Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice
- (2019) Patrick E. Steadman et al. NEURON
- Continuous and Discrete Neuron Types of the Adult Murine Striatum
- (2019) Geoffrey Stanley et al. NEURON
- Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics
- (2018) Kelly Street et al. BMC GENOMICS
- Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
- (2018) Aleksandra Deczkowska et al. CELL
- Integrating single-cell transcriptomic data across different conditions, technologies, and species
- (2018) Andrew Butler et al. NATURE BIOTECHNOLOGY
- Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies
- (2018) Zhana Haimon et al. NATURE IMMUNOLOGY
- Epigenetic regulation of brain region-specific microglia clearance activity
- (2018) Pinar Ayata et al. NATURE NEUROSCIENCE
- Defective cholesterol clearance limits remyelination in the aged central nervous system
- (2018) Ludovico Cantuti-Castelvetri et al. SCIENCE
- A carbon nanotube tape for serial-section electron microscopy of brain ultrastructure
- (2018) Yoshiyuki Kubota et al. Nature Communications
- Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models
- (2018) Brad A. Friedman et al. Cell Reports
- White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes
- (2018) Sara E. Nasrabady et al. Acta Neuropathologica Communications
- From Light Microscopy to Analytical Scanning Electron Microscopy (SEM) and Focused Ion Beam (FIB)/SEM in Biology: Fixed Coordinates, Flat Embedding, Absolute References
- (2018) Manja Luckner et al. MICROSCOPY AND MICROANALYSIS
- TREM2 triggers microglial density and age‐related neuronal loss
- (2018) Bettina Linnartz‐Gerlach et al. GLIA
- Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
- (2018) Timothy R. Hammond et al. IMMUNITY
- Nanobody immunostaining for correlated light and electron microscopy with preservation of ultrastructure
- (2018) Tao Fang et al. NATURE METHODS
- Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing
- (2018) Qingyun Li et al. NEURON
- STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
- (2018) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- Microglia emerge as central players in brain disease
- (2017) Michael W Salter et al. NATURE MEDICINE
- Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging
- (2017) Petra Füger et al. NATURE NEUROSCIENCE
- Wrapped to Adapt: Experience-Dependent Myelination
- (2017) Christopher W. Mount et al. NEURON
- Elucidating the Role of TREM2 in Alzheimer’s Disease
- (2017) Jason D. Ulrich et al. NEURON
- Detecting Activated Cell Populations Using Single-Cell RNA-Seq
- (2017) Ye Emily Wu et al. NEURON
- Massively parallel digital transcriptional profiling of single cells
- (2017) Grace X. Y. Zheng et al. Nature Communications
- Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution
- (2017) Hansruedi Mathys et al. Cell Reports
- White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network
- (2016) Seonjoo Lee et al. ANNALS OF NEUROLOGY
- Inhomogeneous distribution of Iba-1 characterizes microglial pathology in Alzheimer's disease
- (2016) Jasmin Tischer et al. GLIA
- TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
- (2016) Yaming Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Age-related myelin degradation burdens the clearance function of microglia during aging
- (2016) Shima Safaiyan et al. NATURE NEUROSCIENCE
- Microglial brain region−dependent diversity and selective regional sensitivities to aging
- (2016) Kathleen Grabert et al. NATURE NEUROSCIENCE
- Cognitive deficits in single App knock-in mouse models
- (2016) Akira Masuda et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
- (2016) Felix L. Yeh et al. NEURON
- Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq
- (2016) Ozgun Gokce et al. Cell Reports
- TREM2 regulates microglial cell activation in response to demyelination in vivo
- (2015) Claudia Cantoni et al. ACTA NEUROPATHOLOGICA
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
- (2015) Yuka Atagi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Triggering Receptor Expressed on Myeloid Cells 2 Binds Apolipoprotein E
- (2015) Charles C. Bailey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TREM2 sustains microglial expansion during aging and response to demyelination
- (2015) Pietro Luigi Poliani et al. JOURNAL OF CLINICAL INVESTIGATION
- White matter hyperintensities, cognitive impairment and dementia: an update
- (2015) Niels D. Prins et al. Nature Reviews Neurology
- Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques
- (2015) Carlo Condello et al. Nature Communications
- Full-length RNA-seq from single cells using Smart-seq2
- (2014) Simone Picelli et al. Nature Protocols
- Microglial priming in neurodegenerative disease
- (2014) V. Hugh Perry et al. Nature Reviews Neurology
- Motor skill learning requires active central myelination
- (2014) I. A. McKenzie et al. SCIENCE
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- High-contrast en bloc staining of neuronal tissue for field emission scanning electron microscopy
- (2012) Juan Carlos Tapia et al. Nature Protocols
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- TrakEM2 Software for Neural Circuit Reconstruction
- (2012) Albert Cardona et al. PLoS One
- Nasu–Hakola disease and primary microglial dysfunction
- (2010) Marino M. Bianchin et al. Nature Reviews Neurology
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