Transient receptor potential channels in sensory mechanisms of the lower urinary tract

TRPV4 Mediates Acute Bladder Responses to Bacterial Lipopolysaccharides

(2020) Yeranddy A. Alpizar et al.   Frontiers in Immunology

Bladder overactivity and afferent hyperexcitability induced by prostate-to-bladder cross-sensitization in rats with prostatic inflammation

(2019) Yasuhito Funahashi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Autonomic dysregulation at multiple sites is implicated in age‐associated underactive bladder in female mice

(2019) Mariana Gonçalves Oliveira et al.   NEUROUROLOGY AND URODYNAMICS

TRPV4 receptor as a functional sensory molecule in bladder urothelium: Stretch‐independent, tissue‐specific actions and pathological implications

(2019) Max W. G. Roberts et al.   FASEB JOURNAL

TRPV1 in experimental autoimmune prostatitis

(2019) Kenny Roman et al.   PROSTATE

Cross-organ sensitization between the colon and bladder: to pee or not to pee?

(2018) Luke Grundy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Urothelial bladder afferent neurons in the rat are anatomically and neurochemically distinct from non-urothelial afferents

(2018) Buffie J. Clodfelder-Miller et al.   BRAIN RESEARCH

Intravesical Activation of the Cation Channel TRPV4 Improves Bladder Function in a Rat Model for Detrusor Underactivity

(2018) Yves Deruyver et al.   EUROPEAN UROLOGY

Single-cell RNAseq reveals seven classes of colonic sensory neuron

(2018) James R F Hockley et al.   GUT

TRPV1 alterations in urinary bladder dysfunction in a rat model of STZ-induced diabetes

(2018) Bizhan R. Sharopov et al.   LIFE SCIENCES

Effects of nerve growth factor neutralization on TRP channel expression in laser-captured bladder afferent neurons in mice with spinal cord injury

(2018) Nobutaka Shimizu et al.   NEUROSCIENCE LETTERS

KPR-2579, a novel TRPM8 antagonist, inhibits acetic acid-induced bladder afferent hyperactivity in rats

(2018) Naoki Aizawa et al.   NEUROUROLOGY AND URODYNAMICS

Detecting and Avoiding Problems When Using the Cre–lox System

(2018) Allisa J. Song et al.   TRENDS IN GENETICS

The oscillation of intracellular Ca2+ influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium

(2018) Tatsuya Ihara et al.   Scientific Reports

TRPV1 enhances the afferent response to P2X receptor activation in the mouse urinary bladder

(2018) Luke Grundy et al.   Scientific Reports

Muscarinic receptor-induced contractions of the detrusor are impaired in TRPC4 deficient mice

(2018) Caoimhin S. Griffin et al.   Scientific Reports

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

A TRP channel trio mediates acute noxious heat sensing

(2018) Ine Vandewauw et al.   NATURE

Involvement of TRPM4 in detrusor overactivity following spinal cord transection in mice

(2018) F. Aura Kullmann et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Effect of TRPV4 activation in a rat model of detrusor underactivity induced by bilateral pelvic nerve crush injury

(2018) Ei-ichiro Takaoka et al.   NEUROUROLOGY AND URODYNAMICS

Attenuated lipopolysaccharide-induced inflammatory bladder hypersensitivity in mice deficient of transient receptor potential ankilin1

(2018) Jun Kamei et al.   Scientific Reports

Innervation of the Epithelium and Lamina Propria of the Urethra of the Female Rat

(2018) Monica Eggermont et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

TRPM4 channel is involved in regulating epithelial to mesenchymal transition, migration, and invasion of prostate cancer cell lines

(2018) Alfredo I. Sagredo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Gain-of-function mutations in TRPM4 activation gate cause progressive symmetric erythrokeratoderma

(2018) Huijun Wang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

A wireless closed-loop system for optogenetic peripheral neuromodulation

(2018) Aaron D. Mickle et al.   NATURE

A corticopontine circuit for initiation of urination

(2018) Jiwei Yao et al.   NATURE NEUROSCIENCE

RQ-00434739, a novel TRPM8 antagonist, inhibits prostaglandin E2-induced hyperactivity of the primary bladder afferent nerves in rats

(2018) Naoki Aizawa et al.   LIFE SCIENCES

Identifying unique subtypes of spinal afferent nerve endings within the urinary bladder of mice

(2017) Nick J. Spencer et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Sensory feedback from the urethra evokes state-dependent lower urinary tract reflexes in rat

(2017) Zachary C. Danziger et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Circadian expression of Piezo1 , TRPV4 , Connexin26 , and VNUT , associated with the expression levels of the clock genes in mouse primary cultured urothelial cells

(2017) Tatsuya Ihara et al.   NEUROUROLOGY AND URODYNAMICS

Intravesical vanilloids for treating neurogenic lower urinary tract dysfunction in patients with multiple sclerosis: A systematic review and meta-analysis. A report from the Neuro-Urology Promotion Committee of the International Continence Society (ICS)

(2017) Véronique Phé et al.   NEUROUROLOGY AND URODYNAMICS

TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells

(2017) Yeranddy A. Alpizar et al.   Nature Communications

Optogenetic Modulation of Urinary Bladder Contraction for Lower Urinary Tract Dysfunction

(2017) Jae Hong Park et al.   Scientific Reports

TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization

(2017) Olivier Gouin et al.   Protein & Cell

Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes

(2017) M Rocio Servin-Vences et al.   eLife

Premature contractions of the bladder are suppressed by interactions between TRPV4 and SK3 channels in murine detrusor PDGFRα+ cells

(2017) Haeyeong Lee et al.   Scientific Reports

Optogenetic silencing of nociceptive primary afferents reduces evoked and ongoing bladder pain

(2017) Vijay K. Samineni et al.   Scientific Reports

Novel regulatory mechanism in human urinary bladder: central role of transient receptor potential melastatin 4 channels in detrusor smooth muscle function

(2016) Kiril L. Hristov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

TRPM8 antagonists to treat lower urinary tract symptoms: don't lose your cool just yet

(2016) Wouter Everaerts et al.   BJU INTERNATIONAL

Electrophysiological properties of lumbosacral primary afferent neurons innervating urothelial and non-urothelial layers of mouse urinary bladder

(2016) Hirosato Kanda et al.   BRAIN RESEARCH

Transient contractions of urinary bladder smooth muscle are drivers of afferent nerve activity during filling

(2016) Thomas J. Heppner et al.   JOURNAL OF GENERAL PHYSIOLOGY

Muscarinic Receptor Induced Contractions of the Detrusor are Mediated by Activation of TRPC4 Channels

(2016) Caoimhin S. Griffin et al.   JOURNAL OF UROLOGY

The impact of extended lymph node dissection versus neoadjuvant therapy with limited lymph node dissection on biochemical recurrence in high-risk prostate cancer patients treated with radical prostatectomy: a multi-institutional analysis

(2016) Takuma Narita et al.   MEDICAL ONCOLOGY

The Clock mutant mouse is a novel experimental model for nocturia and nocturnal polyuria

(2016) Tatsuya Ihara et al.   NEUROUROLOGY AND URODYNAMICS

Social stress in mice induces urinary bladder overactivity and increases TRPV1 channel-dependent afferent nerve activity

(2015) Gerald C. Mingin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Functional role of the transient receptor potential melastatin 8 (TRPM8) ion channel in the urinary bladder assessed by conscious cystometry andex vivomeasurements of single-unit mechanosensitive bladder afferent activities in the rat

(2015) Hiroki Ito et al.   BJU INTERNATIONAL

Transient receptor potential channel modulators as pharmacological treatments for lower urinary tract symptoms (LUTS): myth or reality?

(2015) Yves Deruyver et al.   BJU INTERNATIONAL

9-Phenanthrol inhibits recombinant and arterial myocyte TMEM16A channels

(2015) Sarah K Burris et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Underactive Bladder: A New Clinical Concept?

(2015) Christopher R. Chapple et al.   EUROPEAN UROLOGY

Essential Role of Transient Receptor Potential M8 (TRPM8) in a Model of Acute Cold-induced Urinary Urgency

(2015) Pieter Uvin et al.   EUROPEAN UROLOGY

Trpm7 Protein Contributes to Intercellular Junction Formation in Mouse Urothelium

(2015) Masaki Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neural control of micturition in humans: a working model

(2015) Derek Griffiths   Nature Reviews Urology

Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice – potential role of TRPA1 in osteoarthritis

(2015) L.J. Moilanen et al.   OSTEOARTHRITIS AND CARTILAGE

A Transient Receptor Potential Ion Channel inChlamydomonasShares Key Features with Sensory Transduction-Associated TRP Channels in Mammals

(2015) Luis Arias-Darraz et al.   PLANT CELL

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain

(2015) Mark D. Andrews et al.   ACS Medicinal Chemistry Letters

Transient receptor potential melastatin 4 channel contributes to migration of androgen-insensitive prostate cancer cells

(2015) Christian Holzmann et al.   Oncotarget

Urate Crystal Induced Inflammation and Joint Pain Are Reduced in Transient Receptor Potential Ankyrin 1 Deficient Mice – Potential Role for Transient Receptor Potential Ankyrin 1 in Gout

(2015) Lauri J. Moilanen et al.   PLoS One

Social stress induces changes in urinary bladder function, bladder NGF content, and generalized bladder inflammation in mice

(2014) Gerald C. Mingin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Intravesical TRPV4 blockade reduces repeated variate stress-induced bladder dysfunction by increasing bladder capacity and decreasing voiding frequency in male rats

(2014) Liana Merrill et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cross-talk between alpha1D-adrenoceptors and transient receptor potential vanilloid type 1 triggers prostate cancer cell proliferation

(2014) Maria Beatrice Morelli et al.   BMC CANCER

TRPM4 inhibitor 9-phenanthrol activates endothelial cell intermediate conductance calcium-activated potassium channels in rat isolated mesenteric artery

(2014) C J Garland et al.   BRITISH JOURNAL OF PHARMACOLOGY

The TRPM4 channel inhibitor 9-phenanthrol

(2014) R Guinamard et al.   BRITISH JOURNAL OF PHARMACOLOGY

The role of TRPM8 in the Guinea-pig bladder-cooling reflex investigated using a novel TRPM8 antagonist

(2014) Jennifer C. Gardiner et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cross-sensitization mechanisms between colon and bladder via transient receptor potential A1 stimulation in rats

(2014) Akira Furuta et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Calcium entry via TRPV1 but not ASICs induces neuropeptide release from sensory neurons

(2014) Aurélien Boillat et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

(2014) Dmitry Usoskin et al.   NATURE NEUROSCIENCE

Contemporary concepts in the aetiopathogenesis of detrusor underactivity

(2014) Nadir I. Osman et al.   Nature Reviews Urology

TRPA1 mediates bladder hyperalgesia in a mouse model of cystitis

(2014) Jennifer J. DeBerry et al.   PAIN

Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes

(2014) K. Deckmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain

(2014) Lavanya Moparthi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Severity of Inflammation Correlates with Elevated Expression of TRPV1 Nerve Fibers and Nerve Growth Factor on Interstitial Cystitis/Bladder Pain Syndrome

(2014) Bo-long Liu et al.   UROLOGIA INTERNATIONALIS

TRPV2 is critical for the maintenance of cardiac structure and function in mice

(2014) Yuki Katanosaka et al.   Nature Communications

TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins

(2014) Victor Meseguer et al.   Nature Communications

Classical Transient Receptor Potential 1 (TRPC1): Channel or Channel Regulator?

(2014) Alexander Dietrich et al.   Cells

Novel role for the transient potential receptor melastatin 4 channel in guinea pig detrusor smooth muscle physiology

(2013) Amy C. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse

(2013) Ine Vandewauw et al.   BMC NEUROSCIENCE

Role of CXCR2 and TRPV1 in functional, inflammatory and behavioural changes in the rat model of cyclophosphamide-induced haemorrhagic cystitis

(2013) Fabiana N Dornelles et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antagonism of the transient receptor potential ankyrin 1 (TRPA1) attenuates hyperalgesia and urinary bladder overactivity in cyclophosphamide-induced haemorrhagic cystitis

(2013) Flavia C. Meotti et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Implication of the TRPM4 nonselective cation channel in mammalian sinus rhythm

(2013) Thomas Hof et al.   HEART RHYTHM

Cold stress induces lower urinary tract symptoms

(2013) Tetsuya Imamura et al.   INTERNATIONAL JOURNAL OF UROLOGY

The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential

(2013) Christophe Simard et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Increased TRPV4 Expression in Urinary Bladder and Lumbosacral Dorsal Root Ganglia in Mice with Chronic Overexpression of NGF in Urothelium

(2013) Beatrice M. Girard et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Co-Cultures Provide a New Tool to Probe Communication Between Adult Sensory Neurons and Urothelium

(2013) Lauren M. O'Mullane et al.   JOURNAL OF UROLOGY

Human white adipocytes express the cold receptor TRPM8 which activation induces UCP1 expression, mitochondrial activation and heat production

(2013) Marco Rossato et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The role of transient receptor potential ankyrin 1 (TRPA1) channel in activation of single unit mechanosensitive bladder afferent activities in the rat

(2013) Tomonori Minagawa et al.   NEUROUROLOGY AND URODYNAMICS

Isoform- and receptor-specific channel property of canonical transient receptor potential (TRPC)1/4 channels

(2013) Jinsung Kim et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Crucial Role of TRPC1 and TRPC4 in Cystitis-Induced Neuronal Sprouting and Bladder Overactivity

(2013) Mathieu Boudes et al.   PLoS One

TRPA1: A Gatekeeper for Inflammation

(2012) Diana M. Bautista et al.   Annual Review of Physiology

Function of Transient Receptor Potential Cation Channel Subfamily V Member 4 (TRPV4) as a Mechanical Transducer in Flow-sensitive Segments of Renal Collecting Duct System

(2012) Jonathan Berrout et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of Transient Receptor Potential Ankyrin 1 in Human Dental Pulp

(2012) Yun Sook Kim et al.   JOURNAL OF ENDODONTICS

NMDA Receptor-Dependent Synaptic Activation of TRPC Channels in Olfactory Bulb Granule Cells

(2012) O. Stroh et al.   JOURNAL OF NEUROSCIENCE

Environmental Cues to Urgency and Leakage Episodes in Patients With Overactive Bladder Syndrome

(2012) Elizabeth Victor et al.   Journal of Wound Ostomy and Continence Nursing

Transient Receptor Potential Melastatin 8 (TRPM8) Channels are Involved in Body Temperature Regulation

(2012) Narender R Gavva et al.   Molecular Pain

TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis

(2012) Benjamin Schattling et al.   NATURE MEDICINE

An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure

(2012) Kevin S. Thorneloe et al.   Science Translational Medicine

Psychosocial Difficulties in Children Referred to Pediatric Urology: A Closer Look

(2012) Cortney Wolfe-Christensen et al.   UROLOGY

Activation of the cold-sensing TRPM8 channel triggers UCP1-dependent thermogenesis and prevents obesity

(2012) Shuangtao Ma et al.   Journal of Molecular Cell Biology

Function of the Cold Receptor (TRPM8) Associated with Voiding Dysfunction in Bladder Outlet Obstruction in Rats

(2012) Ji Hee Jun et al.   International Neurourology Journal

Effects of Combination Treatment of Intravesical Resiniferatoxin Instillation and Hydrodistention in Patients with Refractory Painful Bladder Syndrome/Interstitial Cystitis: A Pilot Study

(2012) Byeong Kuk Ham et al.   International Neurourology Journal

Worldwide prevalence estimates of lower urinary tract symptoms, overactive bladder, urinary incontinence and bladder outlet obstruction

(2011) Debra E. Irwin et al.   BJU INTERNATIONAL

The Capsaicin Receptor TRPV1 Is a Crucial Mediator of the Noxious Effects of Mustard Oil

(2011) Wouter Everaerts et al.   CURRENT BIOLOGY

The GUDMAP database - an online resource for genitourinary research

(2011) S. D. Harding et al.   DEVELOPMENT

Transient Receptor Potential Channel 1 (TRPC1) Reduces Calcium Permeability in Heteromeric Channel Complexes

(2011) Ursula Storch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platelet-derived growth factor receptor-α cells in mouse urinary bladder: a new class of interstitial cells

(2011) Byoung H. Koh et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Human Dental Pulp Fibroblasts Express the “Cold-sensing” Transient Receptor Potential Channels TRPA1 and TRPM8

(2011) Ikhlas A. El Karim et al.   JOURNAL OF ENDODONTICS

The proximodistal aggravation of colitis depends on substance P released from TRPV1-expressing sensory neurons

(2011) Matthias A. Engel et al.   JOURNAL OF GASTROENTEROLOGY

The Expression Pattern of TRPV1 in Brain

(2011) A. Menigoz et al.   JOURNAL OF NEUROSCIENCE

Trpv1 Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells

(2011) D. J. Cavanaugh et al.   JOURNAL OF NEUROSCIENCE

TRP Vanilloid 2 Knock-Out Mice Are Susceptible to Perinatal Lethality But Display Normal Thermal and Mechanical Nociception

(2011) U. Park et al.   JOURNAL OF NEUROSCIENCE

The Mechanoreceptor TRPV4 is Localized in Adherence Junctions of the Human Bladder Urothelium: A Morphological Study

(2011) Dick A.W. Janssen et al.   JOURNAL OF UROLOGY

Mechanoreception in motile flagella of Chlamydomonas

(2011) Kenta Fujiu et al.   NATURE CELL BIOLOGY

OAB. Are we barking up the wrong tree? A lesson from my dog

(2011) Norman R. Zinner   NEUROUROLOGY AND URODYNAMICS

Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat

(2011) Naoki Aizawa et al.   NEUROUROLOGY AND URODYNAMICS

Cholinergic chemosensory cells in the trachea regulate breathing

(2011) G. Krasteva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV1, NK1 receptor and substance P immunoreactivity and gene expression in the rat lumbosacral spinal cord and urinary bladder after systemic, low dose vanilloid administration

(2011) Yujing J. Heng et al.   REGULATORY PEPTIDES

Functional TRPV4 channels and an absence of capsaicin-evoked currents in freshly-isolated, guinea-pig urothelial cells

(2010) Xiaoping Xu et al.   Channels

Gain-of-Function Mutations in TRPM4 Cause Autosomal Dominant Isolated Cardiac Conduction Disease

(2010) Hui Liu et al.   Circulation-Cardiovascular Genetics

Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice

(2010) Ilka Mathar et al.   JOURNAL OF CLINICAL INVESTIGATION

TRPV2 Enhances Axon Outgrowth through Its Activation by Membrane Stretch in Developing Sensory and Motor Neurons

(2010) K. Shibasaki et al.   JOURNAL OF NEUROSCIENCE

TRPA1 Receptor Induced Relaxation of the Human Urethra Involves TRPV1 and Cannabinoid Receptor Mediated Signals, and Cyclooxygenase Activation

(2010) Philipp Weinhold et al.   JOURNAL OF UROLOGY

High-performance genetically targetable optical neural silencing by light-driven proton pumps

(2010) Brian Y. Chow et al.   NATURE

TRPV2 has a pivotal role in macrophage particle binding and phagocytosis

(2010) Tiffany M Link et al.   NATURE IMMUNOLOGY

The bladder–brain connection: putative role of corticotropin-releasing factor

(2010) Rita J. Valentino et al.   Nature Reviews Urology

Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

(2010) W. Everaerts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals

(2010) M. Tizzano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV2 Activation Induces Apoptotic Cell Death in Human T24 Bladder Cancer Cells: A Potential Therapeutic Target for Bladder Cancer

(2010) Takahiro Yamada et al.   UROLOGY

TRPM7 is essential for Mg2+ homeostasis in mammals

(2010) Lillia V. Ryazanova et al.   Nature Communications

Social stress-induced bladder dysfunction: potential role of corticotropin-releasing factor

(2009) Susan K. Wood et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Identification and characterization of novel TRPV4 modulators

(2009) Fabien Vincent et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The prevalence of lower urinary tract symptoms (LUTS) in the USA, the UK and Sweden: results from the Epidemiology of LUTS (EpiLUTS) study

(2009) Karin S. Coyne et al.   BJU INTERNATIONAL

Essential Role for TRPC5 in Amygdala Function and Fear-Related Behavior

(2009) Antonio Riccio et al.   CELL

Deletion of TRPC4 and TRPC6 in Mice Impairs Smooth Muscle Contraction and Intestinal Motility In Vivo

(2009) Volodymyr V. Tsvilovskyy et al.   GASTROENTEROLOGY

The TRPV4 Cation Channel Mediates Stretch-evoked Ca2+Influx and ATP Release in Primary Urothelial Cell Cultures

(2009) Tsutomu Mochizuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of TRPV1 Mediates Calcitonin Gene-Related Peptide Release, Which Excites Trigeminal Sensory Neurons and Is Attenuated by a Retargeted Botulinum Toxin with Anti-Nociceptive Potential

(2009) J. Meng et al.   JOURNAL OF NEUROSCIENCE

TRPV1 Is Activated by Both Acidic and Basic pH

(2009) A. Dhaka et al.   JOURNAL OF NEUROSCIENCE

De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury

(2009) Volodymyr Gerzanich et al.   NATURE MEDICINE

Where is TRPV1 expressed in the bladder, do we see the real channel?

(2009) Wouter Everaerts et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Expression of the TRPM8-immunoreactivity in dorsal root ganglion neurons innervating the rat urinary bladder

(2009) Tokumasa Hayashi et al.   NEUROSCIENCE RESEARCH

The vanilloid transient receptor potential channel TRPV4: From structure to disease

(2009) Wouter Everaerts et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Urinary incontinence in women is not exclusively a medical problem: A population-based study on urinary incontinence and general living conditions

(2009) Karin Franzén et al.   SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY

The economic impact of overactive bladder syndrome in six Western countries

(2008) Debra E. Irwin et al.   BJU INTERNATIONAL

9-Phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels

(2008) T Grand et al.   BRITISH JOURNAL OF PHARMACOLOGY

TRPV4-Mediated Calcium Influx Regulates Terminal Differentiation of Osteoclasts

(2008) Ritsuko Masuyama et al.   Cell Metabolism

Calcium elevation in mouse pancreatic beta cells evoked by extracellular human islet amyloid polypeptide involves activation of the mechanosensitive ion channel TRPV4

(2008) S. Casas et al.   DIABETOLOGIA

Transient Receptor Potential A1 (TRPA1) Activity in the Human Urethra—Evidence for a Functional Role for TRPA1 in the Outflow Region

(2008) Christian Gratzke et al.   EUROPEAN UROLOGY

TRPA1 is a major oxidant sensor in murine airway sensory neurons

(2008) Bret F. Bessac et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential Localizations of the Transient Receptor Potential Channels TRPV4 and TRPV1 in the Mouse Urinary Bladder

(2008) Takahiro Yamada et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Visualizing Cold Spots: TRPM8-Expressing Sensory Neurons and Their Projections

(2008) A. Dhaka et al.   JOURNAL OF NEUROSCIENCE

Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress

(2008) D. A. Andersson et al.   JOURNAL OF NEUROSCIENCE

TRPV2 Is Activated by Cannabidiol and Mediates CGRP Release in Cultured Rat Dorsal Root Ganglion Neurons

(2008) N. Qin et al.   JOURNAL OF NEUROSCIENCE

N-((1S)-1- -3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Part I

(2008) K. S. Thorneloe et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

HC-030031, a TRPA1 Selective Antagonist, Attenuates Inflammatory- and Neuropathy-Induced Mechanical Hypersensitivity

(2008) Samer R Eid et al.   Molecular Pain

The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells

(2008) Gaëtan Barbet et al.   NATURE IMMUNOLOGY

Lack of TRPV1 inhibits cystitis-induced increased mechanical sensitivity in mice

(2008) Zun-Yi Wang et al.   PAIN

TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells

(2008) I. M. Lorenzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of Trpm7 Disrupts Embryonic Development and Thymopoiesis Without Altering Mg2+ Homeostasis

(2008) J. Jin et al.   SCIENCE

Differential Expression Profile of Cold (TRPA1) and Cool (TRPM8) Receptors in Human Urogenital Organs

(2008) Shuqi Du et al.   UROLOGY

Transient Receptor Potential Vanilloid Type 2 (TRPV2) Expression in Normal Urothelium and in Urothelial Carcinoma of Human Bladder: Correlation with the Pathologic Stage

(2007) Sara Caprodossi et al.   EUROPEAN UROLOGY

Distribution and Function of the Hydrogen Sulfide–Sensitive TRPA1 Ion Channel in Rat Urinary Bladder

(2007) Tomi Streng et al.   EUROPEAN UROLOGY

Characterization of Mouse Lumbar Splanchnic and Pelvic Nerve Urinary Bladder Mechanosensory Afferents

(2007) Linjing Xu et al.   JOURNAL OF NEUROPHYSIOLOGY

Cold environmental stress induces detrusor overactivity via resiniferatoxin-sensitive nerves in conscious rats

(2007) Tetsuya Imamura et al.   NEUROUROLOGY AND URODYNAMICS