TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins

Bacteria activate sensory neurons that modulate pain and inflammation

(2013) Isaac M. Chiu et al.   NATURE

TRPA1 channels in the vasculature

(2012) Scott Earley   BRITISH JOURNAL OF PHARMACOLOGY

Hypoxia-inducible Factor-1α (HIF1α) Switches on Transient Receptor Potential Ankyrin Repeat 1 (TRPA1) Gene Expression via a Hypoxia Response Element-like Motif to Modulate Cytokine Release

(2012) Noriyuki Hatano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The transient receptor potential channel TRPA1: from gene to pathophysiology

(2012) Bernd Nilius et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

TRPA1 Has a Key Role in the Somatic Pro-Nociceptive Actions of Hydrogen Sulfide

(2012) David A. Andersson et al.   PLoS One

Photomechanical Responses in Drosophila Photoreceptors

(2012) R. C. Hardie et al.   SCIENCE

The inflammatory response in sepsis

(2012) Markus Bosmann et al.   TRENDS IN IMMUNOLOGY

TRPA1 and Substance P Mediate Colitis in Mice

(2011) Matthias A. Engel et al.   GASTROENTEROLOGY

LPS Sensitizes TRPV1 via Activation of TLR4 in Trigeminal Sensory Neurons

(2011) A. Diogenes et al.   JOURNAL OF DENTAL RESEARCH

TRPA1 underlies a sensing mechanism for O2

(2011) Nobuaki Takahashi et al.   Nature Chemical Biology

Bacterial cell products signal to mouse colonic nociceptive dorsal root ganglia neurons

(2010) Fernando Ochoa-Cortes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Evidence for the pathophysiological relevance of TRPA1 receptors in the cardiovascular system in vivo

(2010) G. Pozsgai et al.   CARDIOVASCULAR RESEARCH

TRPA1 channels: Novel targets of 1,4-dihydropyridines

(2010) Otto Fajardo et al.   Channels

TAK-242 (Resatorvid), a Small-Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules

(2010) N. Matsunaga et al.   MOLECULAR PHARMACOLOGY

Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception

(2010) Kyeongjin Kang et al.   NATURE

TRPA1 Mediates Mechanical Currents in the Plasma Membrane of Mouse Sensory Neurons

(2010) Daniel Vilceanu et al.   PLoS One

Drosophila TRPA1 channel mediates chemical avoidance in gustatory receptor neurons

(2010) S. H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plant and Animal Sensors of Conserved Microbial Signatures

(2010) P. C. Ronald et al.   SCIENCE

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

TRPV1 controls acid- and heat-induced calcitonin gene-related peptide release and sensitization by bradykinin in the isolated mouse trachea

(2009) Tatjana I. Kichko et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli

(2009) Stuart M. Brierley et al.   GASTROENTEROLOGY

TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons

(2009) K. Y. Kwan et al.   JOURNAL OF NEUROSCIENCE

A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma

(2009) A. I. Caceres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipopolysaccharide-induced hypotension is mediated by a neural pathway involving the vagus nerve, the nucleus tractus solitarius and alpha-adrenergic receptors in the preoptic anterior hypothalamic area

(2008) M. Sertac Yilmaz et al.   JOURNAL OF NEUROIMMUNOLOGY

TRPA1 Channels Mediate Cold Temperature Sensing in Mammalian Vagal Sensory Neurons: Pharmacological and Genetic Evidence

(2008) O. Fajardo et al.   JOURNAL OF NEUROSCIENCE