SIRT1, a promising regulator of bone homeostasis

Sirtuin-1 and Its Relevance in Vascular Calcification

(2020) Chien-Lin Lu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Suppression of osteogenic differentiation and mitochondrial function change in human periodontal ligament stem cells by melatonin at physiological levels

(2020) Miaomiao Zheng et al.   PeerJ

17β-Estradiol improves osteoblastic cell function through the Sirt1/NF-κB/MMP-8 pathway

(2020) H.-L. Zuo et al.   CLIMACTERIC

Functional Relationship between Osteogenesis and Angiogenesis in Tissue Regeneration

(2020) Francesca Diomede et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Resveratrol promotes osteogenesis via activating SIRT1/FoxO1 pathway in osteoporosis mice

(2020) Yixuan Jiang et al.   LIFE SCIENCES

Comparison between teriparatide and bisphosphonates for improving bone mineral density in postmenopausal osteoporosis patients

(2020) Guiyong Fan et al.   MEDICINE

Nicotinamide mononucleotide attenuates glucocorticoid‑induced osteogenic inhibition by regulating the SIRT1/PGC‑1α signaling pathway

(2020) Rui‑Xiong Huang et al.   Molecular Medicine Reports

MiR-155 inhibition alleviates suppression of osteoblastic differentiation by high glucose and free fatty acids in human bone marrow stromal cells by upregulating SIRT1

(2020) Bo Qu et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Activation of FoxO1/SIRT1/RANKL/OPG pathway may underlie the therapeutic effects of resveratrol on aging-dependent male osteoporosis

(2020) Omnia Ameen et al.   BMC MUSCULOSKELETAL DISORDERS

Sirtuin 1 deficiency decreases bone mass and increases bone marrow adiposity in a mouse model of chronic energy deficiency

(2020) Loïc Louvet et al.   BONE

β-mercaptoethanol promotes osteogenesis of human mesenchymal stem cells via sirt1-ERK pathway

(2020) Jiaxing Liu et al.   CYTOTECHNOLOGY

Suppression of SIRT1 in Diabetic Conditions Induces Osteogenic Differentiation of Human Vascular Smooth Muscle Cells via RUNX2 Signalling

(2019) F. Bartoli-Leonard et al.   Scientific Reports

Sirt1 Promotes Osteogenic Differentiation and Increases Alveolar Bone Mass via Bmi1 Activation in Mice

(2019) Hua Wang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

On mechanically driven biological stimulus for bone remodeling as a diffusive phenomenon

(2019) Ivan Giorgio et al.   Biomechanics and Modeling in Mechanobiology

Sirtuins and FoxOs in osteoporosis and osteoarthritis

(2019) Maria Almeida et al.   BONE

Treatment of mandibular osteoradionecrosis by periosteal free flaps

(2019) J. Bettoni et al.   BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY

Drugs targeting SIRT1, a new generation of therapeutics for osteoporosis and other bone related disorders?

(2019) Kayvan Zainabadi   PHARMACOLOGICAL RESEARCH

Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrow

(2019) Jie Song et al.   Cell Death & Disease

“Tree to Bone”: Lignin/Polycaprolactone Nanofibers for Hydroxyapatite Biomineralization

(2019) Ding Wang et al.   BIOMACROMOLECULES

Gaucher Disease in Bone: From Pathophysiology to Practice

(2019) Derralynn Hughes et al.   JOURNAL OF BONE AND MINERAL RESEARCH

SIRT1 suppresses p53-dependent apoptosis by modulation of p21 in osteoblast-like MC3T3-E1 cells exposed to fluoride

(2019) Xiaolong Gu et al.   TOXICOLOGY IN VITRO

Inositol pyrophosphates mediated the apoptosis induced by hypoxic injury in bone marrow-derived mesenchymal stem cells by autophagy

(2019) Jingyu Deng et al.   Stem Cell Research & Therapy

MicroRNA‐506 upregulation contributes to sirtuin 1 inhibition of osteoclastogenesis in bone marrow stromal cells induced by TNF‐α treatment

(2019) Shu Yan et al.   CELL BIOCHEMISTRY AND FUNCTION

Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity

(2019) Juliane-Susanne Jung et al.   Cellular Reprogramming

Glycyrrhizic acid suppresses osteoclast differentiation and postmenopausal osteoporosis by modulating the NF-κB, ERK, and JNK signaling pathways

(2019) Ziqing Yin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Melatonin restores the osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells by preserving SIRT1-mediated intracellular antioxidant properties

(2019) Weikai Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Recovery Of Bone And Muscle Mass In Patients With Chronic Kidney Disease And Iron Overload On Hemodialysis And Taking Combined Supplementation With Curcumin And Resveratrol

(2019) Blanca Olivia Murillo Ortiz et al.   Clinical Interventions in Aging

Update on Menopausal Hormone Therapy for Fracture Prevention

(2019) Jan J. Stepan et al.   Current Osteoporosis Reports

NF-κB Signaling Regulates Physiological and Pathological Chondrogenesis

(2019) Eijiro Jimi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Estrogen-SIRT1 Axis Plays a Pivotal Role in Protecting Arteries Against Menopause-Induced Senescence and Atherosclerosis

(2019) Yuichi Sasaki et al.   Journal of Atherosclerosis and Thrombosis

The Role and Mechanism of SIRT1 in Resveratrol-regulated Osteoblast Autophagy in Osteoporosis Rats

(2019) Xuhao Yang et al.   Scientific Reports

MiR-449 overexpression inhibits osteogenic differentiation of bone marrow mesenchymal stem cells via suppressing Sirt1/Fra-1 pathway in high glucose and free fatty acids microenvironment

(2018) Bo Qu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fam83h mutation inhibits the mineralization in ameloblasts by activating Wnt/β-catenin signaling pathway

(2018) Mei Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Particle-induced SIRT1 downregulation promotes osteoclastogenesis and osteolysis through ER stress regulation

(2018) Liang Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

SIRT1 and microRNAs: The role in breast, lung and prostate cancers

(2018) Hedyieh Karbasforooshan et al.   EXPERIMENTAL CELL RESEARCH

Spontaneous up-regulation of SIRT1 during osteogenesis contributes to stem cells’ resistance to oxidative stress

(2018) Mao Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

NAMPT expression in osteoblasts controls osteoclast recruitment in alveolar bone remodeling

(2018) Bassam Hassan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Overexpression of Sirt1 in Mesenchymal Stem Cells Protects against Bone Loss in Mice by FOXO3a Deacetylation and Oxidative Stress Inhibition

(2018) Wen Sun et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

SIRT1 suppresses high glucose and palmitate-induced osteoclast differentiation via deacetylating p66Shc

(2018) Bo Qu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Sirtuin activators and inhibitors: Promises, achievements, and challenges

(2018) Han Dai et al.   PHARMACOLOGY & THERAPEUTICS

Resveratrol Attenuates Lipopolysaccharides (LPS)-Induced Inhibition of Osteoblast Differentiation in MC3T3-E1 Cells

(2018) Jun Ma et al.   MEDICAL SCIENCE MONITOR

Perivascular Adipose Tissue as a Relevant Fat Depot for Cardiovascular Risk in Obesity

(2018) Rafael M. Costa et al.   Frontiers in Physiology

Role of Marrow Adipocytes in Regulation of Energy Metabolism and Bone Homeostasis

(2018) Jillian Cornish et al.   Current Osteoporosis Reports

Comparison of bone turnover markers in peripheral blood and bone marrow aspirate

(2018) M.J. Ornstrup et al.   BONE

Mechanical stretch induces antioxidant responses and osteogenic differentiation in human mesenchymal stem cells through activation of the AMPK-SIRT1 signaling pathway

(2018) Xi Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of resveratrol on bone health in type 2 diabetic patients. A double-blind randomized-controlled trial

(2018) Simona Bo et al.   Nutrition & Diabetes

SIRT1 and Estrogen Signaling Cooperation for Breast Cancer Onset and Progression

(2018) Sergio Liarte et al.   Frontiers in Endocrinology

Runx1 regulates osteogenic differentiation of BMSCs by inhibiting adipogenesis through Wnt/β-catenin pathway

(2018) Yuan Luo et al.   ARCHIVES OF ORAL BIOLOGY

Genistein protects against ox-LDL-induced senescence through enhancing SIRT1/LKB1/AMPK-mediated autophagy flux in HUVECs

(2018) Huaping Zhang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Nicotinamide phosphoribosyltransferase (Nampt) may serve as the marker for osteoblast differentiation of bone marrow-derived mesenchymal stem cells

(2017) Xu He et al.   EXPERIMENTAL CELL RESEARCH

SIRT1/HERC4 Locus Associated With Bisphosphonate-Induced Osteonecrosis of the Jaw: An Exome-Wide Association Analysis

(2017) Guang Yang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

SIRT1-SIRT3 Axis Regulates Cellular Response to Oxidative Stress and Etoposide

(2017) Ilaria Carnevale et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Coalignment of osteocyte canaliculi and collagen fibers in human osteonal bone

(2017) Felix Repp et al.   JOURNAL OF STRUCTURAL BIOLOGY

Romosozumab (sclerostin monoclonal antibody) versus teriparatide in postmenopausal women with osteoporosis transitioning from oral bisphosphonate therapy: a randomised, open-label, phase 3 trial

(2017) Bente L Langdahl et al.   LANCET

Overexpression of SIRT1 prevents hypoxia-induced apoptosis in osteoblast cells

(2017) Lu Zhou et al.   Molecular Medicine Reports

Obesity is a concern for bone health with aging

(2017) Sue A. Shapses et al.   NUTRITION RESEARCH

Resveratrol suppresses the alveolar bone resorption induced by artificial trauma from occlusion in mice

(2017) Y Matsuda et al.   ORAL DISEASES

Sirt1 Inhibits Oxidative Stress in Vascular Endothelial Cells

(2017) Weijin Zhang et al.   Oxidative Medicine and Cellular Longevity

CACUL1 reciprocally regulates SIRT1 and LSD1 to repress PPARγ and inhibit adipogenesis

(2017) Min Jun Jang et al.   Cell Death & Disease

Interferon β protects against avascular osteonecrosis through interleukin 6 inhibition and silent information regulator transcript-1 upregulation

(2017) Kyoung Min Kim et al.   Oncotarget

10 years of denosumab treatment in postmenopausal women with osteoporosis: results from the phase 3 randomised FREEDOM trial and open-label extension

(2017) Henry G Bone et al.   Lancet Diabetes & Endocrinology

SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis

(2017) Kayvan Zainabadi et al.   PLoS One

An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers

(2017) Sophia E. Airhart et al.   PLoS One

MiR-132 regulates osteogenic differentiation via downregulating Sirtuin1 in a peroxisome proliferator-activated receptor β/δ–dependent manner

(2016) Kai Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Equine metabolic syndrome impairs adipose stem cells osteogenic differentiation by predominance of autophagy over selective mitophagy

(2016) Krzysztof Marycz et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mechanism of osteogenic and adipogenic differentiation of tendon stem cells induced by sirtuin 1

(2016) Junpeng Liu et al.   Molecular Medicine Reports

Postmenopausal Osteoporosis

(2016) Dennis M. Black et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reduced Sirtuin1 expression at the femoral neck in women who sustained an osteoporotic hip fracture

(2016) M. El-Haj et al.   OSTEOPOROSIS INTERNATIONAL

Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo

(2016) Deheng Chen et al.   Cell Death & Disease

Cellular localization of NRF2 determines the self-renewal and osteogenic differentiation potential of human MSCs via the P53–SIRT1 axis

(2016) D S Yoon et al.   Cell Death & Disease

SIRT1-mediated FoxOs pathways protect against apoptosis by promoting autophagy in osteoblast-like MC3T3-E1 cells exposed to sodium fluoride

(2016) Xiaolong Gu et al.   Oncotarget

SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro

(2016) Yuanfei Zhou et al.   Oncotarget

Different effects of resveratrol on early and late passage mesenchymal stem cells through β-catenin regulation

(2015) Dong Suk Yoon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Suppression of RANKL-induced osteoclast differentiation by cilostazol via SIRT1-induced RANK inhibition

(2015) So Youn Park et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Endoplasmic reticulum stress-mediated inflammatory signaling pathways within the osteolytic periosteum and interface membrane in particle-induced osteolysis

(2015) Guoyin Liu et al.   CELL AND TISSUE RESEARCH

Sirtuin 1 Is a Negative Regulator of Parathyroid Hormone Stimulation of Matrix Metalloproteinase 13 Expression in Osteoblastic Cells

(2015) Yurong Fei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases

(2015) Danielle A. Callaway et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Resveratrol Potentiates Vitamin D and Nuclear Receptor Signaling

(2015) Angelika Dampf Stone et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

SIRT1 Protects Against Oxidative Stress-Induced Endothelial Progenitor Cells Apoptosis by Inhibiting FOXO3a via FOXO3a Ubiquitination and Degradation

(2015) Yu-Qiang Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs

(2015) Ha-Neui Kim et al.   MOLECULAR ENDOCRINOLOGY

Short-term and long-term effects of osteoporosis therapies

(2015) Ian R. Reid   Nature Reviews Endocrinology

A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease

(2015) R. Scott Turner et al.   NEUROLOGY

2,4,5-Trimethoxyldalbergiquinol promotes osteoblastic differentiation and mineralization via the BMP and Wnt/β-catenin pathway

(2015) H-M Yun et al.   Cell Death & Disease

Protective effects of resveratrol on postmenopausal osteoporosis: regulation of SIRT1-NF-κB signaling pathway

(2014) Jing Feng et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Identification of serum sirtuins as novel noninvasive protein markers for frailty

(2014) Rahul Kumar et al.   AGING CELL

Autophagy in osteoblasts is involved in mineralization and bone homeostasis

(2014) Marie Nollet et al.   Autophagy

Angiotensin II induces mitochondrial oxidative stress and mtDNA damage in osteoblasts by inhibiting SIRT1–FoxO3a–MnSOD pathway

(2014) Yong Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bone marrow blood vessel ossification and “microvascular dead space” in rat and human long bone

(2014) Rhonda D. Prisby   BONE

Intracellular NAMPT–NAD+–SIRT1 cascade improves post-ischaemic vascular repair by modulating Notch signalling in endothelial progenitors

(2014) Pei Wang et al.   CARDIOVASCULAR RESEARCH

Senescence and apoptosis: dueling or complementary cell fates?

(2014) B. G. Childs et al.   EMBO REPORTS

The Sirtuin1 Activator SRT3025 Down-Regulates Sclerostin and Rescues Ovariectomy-Induced Bone Loss and Biomechanical Deterioration in Female Mice

(2014) Hanna Artsi et al.   ENDOCRINOLOGY

BRG1 expression is increased in thoracic aortic aneurysms and regulates proliferation and apoptosis of vascular smooth muscle cells through the long non-coding RNA HIF1A-AS1 in vitro

(2014) Shuwei Wang et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Sirtuin1 (Sirt1) Promotes Cortical Bone Formation by Preventing β-Catenin Sequestration by FoxO Transcription Factors in Osteoblast Progenitors

(2014) Srividhya Iyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiaging Properties of a Grape-Derived Antioxidant Are Regulated by Mitochondrial Balance of Fusion and Fission Leading to Mitophagy Triggered by a Signaling Network of Sirt1-Sirt3-Foxo3-PINK1-PARKIN

(2014) Somak Das et al.   Oxidative Medicine and Cellular Longevity

Caspase-2 Maintains Bone Homeostasis by Inducing Apoptosis of Oxidatively-Damaged Osteoclasts

(2014) Ramaswamy Sharma et al.   PLoS One

SIRT1 Directly Regulates SOX2 to Maintain Self-Renewal and Multipotency in Bone Marrow-Derived Mesenchymal Stem Cells

(2014) Dong Suk Yoon et al.   STEM CELLS

SIRT1 and other sirtuins in metabolism

(2014) Hung-Chun Chang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Effects of Resveratrol Supplementation on Bone Growth in Young Rats and Microarchitecture and Remodeling in Ageing Rats

(2014) Alice Lee et al.   Nutrients

SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin

(2014) Huiqiang Chen et al.   Frontiers in Aging Neuroscience

SIRT1 Inhibition Affects Angiogenic Properties of Human MSCs

(2014) Botti Chiara et al.   Biomed Research International

Role of SIRT1 and AMPK in mesenchymal stem cells differentiation

(2013) Huiqiang Chen et al.   AGEING RESEARCH REVIEWS

Low sirtuin 1 levels in human osteoarthritis subchondral osteoblasts lead to abnormal sclerostin expression which decreases Wnt/β-catenin activity

(2013) Élie Abed et al.   BONE

SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin

(2013) Petra Simic et al.   EMBO Molecular Medicine

NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity

(2013) Sathisha Upparahalli Venkateshaiah et al.   EXPERIMENTAL HEMATOLOGY

Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process

(2013) Antero Salminen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Blueberry consumption prevents loss of collagen in bone matrix and inhibits senescence pathways in osteoblastic cells

(2012) Jian Zhang et al.   AGE

Measles virus nucleocapsid protein, a key contributor to Paget's disease, increases IL-6 expression via down-regulation of FoxO3/Sirt1 signaling

(2012) Feng-Ming Wang et al.   BONE

Porphyromonas gingivalis lipopolysaccharide regulates interleukin (IL)-17 and IL-23 expression via SIRT1 modulation in human periodontal ligament cells

(2012) Yong-Duk Park et al.   CYTOKINE

Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling

(2012) James R Edwards et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Resveratrol Mediated Modulation of Sirt-1/Runx2 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells: Potential Role of Runx2 Deacetylation

(2012) Mehdi Shakibaei et al.   PLoS One

Resveratrol Exerts Dosage and Duration Dependent Effect on Human Mesenchymal Stem Cell Development

(2012) Lindsay Peltz et al.   PLoS One

EXPRESSION OF SIRT1 IN CHOROIDAL NEOVASCULAR MEMBRANES

(2012) Shawn C. Maloney et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Sirt1 Is a Regulator of Bone Mass and a Repressor ofSostEncoding for Sclerostin, a Bone Formation Inhibitor

(2011) Einav Cohen-Kfir et al.   ENDOCRINOLOGY

Oxidative stress induces senescence in human mesenchymal stem cells

(2011) Anita Brandl et al.   EXPERIMENTAL CELL RESEARCH

PGC-1α Mediates Differentiation of Mesenchymal Stem Cells to Brown Adipose Cells

(2011) Pin-I Huang et al.   Journal of Atherosclerosis and Thrombosis

Resveratrol-mediated SIRT-1 Interactions with p300 Modulate Receptor Activator of NF-κB Ligand (RANKL) Activation of NF-κB Signaling and Inhibit Osteoclastogenesis in Bone-derived Cells

(2011) Mehdi Shakibaei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: A possible cause for reduced osteogenesis and increased adipogenesis in older individuals

(2011) Yan Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism

(2011) Gerald J Atkins et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Resveratrol promotes osteogenesis of human mesenchymal stem cells by upregulating RUNX2 gene expression via the SIRT1/FOXO3A axis

(2011) Pei-Chi Tseng et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The role of sirtuin 1 in osteoblastic differentiation in human periodontal ligament cells

(2011) Y.-M. Lee et al.   JOURNAL OF PERIODONTAL RESEARCH

Advances in osteoclast biology: old findings and new insights from mouse models

(2011) James R. Edwards et al.   Nature Reviews Rheumatology

Cigarette smoke-induced autophagy is regulated by SIRT1–PARP-1-dependent mechanism: Implication in pathogenesis of COPD

(2010) Jae-woong Hwang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Resveratrol prevents RANKL-induced osteoclast differentiation of murine osteoclast progenitor RAW 264.7 cells through inhibition of ROS production

(2010) Xu He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

C/EBPα regulates SIRT1 expression during adipogenesis

(2010) Qihuang Jin et al.   CELL RESEARCH

Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats

(2010) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

SIRT1 modulates high-mobility group box 1-induced osteoclastogenic cytokines in human periodontal ligament cells

(2010) Young-Suk Kim et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Potential involvement of SIRT1 in the pathogenesis of osteoarthritis through the modulation of chondrocyte gene expressions

(2010) Norifumi Fujita et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

Effect of estrogens on bone marrow adipogenesis and Sirt1 in aging C57BL/6J mice

(2009) Alexander Elbaz et al.   BIOGERONTOLOGY

Calorie Restriction and Bone Health in Young, Overweight Individuals

(2008) Leanne M. Redman   ARCHIVES OF INTERNAL MEDICINE

Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling

(2008) Chang Hyun Byon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH