Bioactive half-sandwich Rh and Ir bipyridyl complexes containing artemisinin

Enhancing the Activity of Drugs by Conjugation to Organometallic Fragments

(2020) Prinessa Chellan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bio-organometallic peptide conjugates: recent advances in their synthesis and prospects for biomedical application

(2020) Fanny Guzman et al.   CURRENT ORGANIC CHEMISTRY

First insights into the novel class of organometallic compounds bearing a bidentate selenopyridone coordination motif: Synthesis, characterization, stability and biological investigations

(2020) Sophia Harringer et al.   INORGANICA CHIMICA ACTA

Evaluation of anticancer role of a novel ruthenium(II)-based compound compared with NAMI-A and cisplatin in impairing mitochondrial functionality and promoting oxidative stress in triple negative breast cancer models

(2020) Sonia Silvestri et al.   MITOCHONDRION

Drive to organoruthenium and organoiridium complexes from organoplatinum: Next-generation anticancer metallotherapeutics

(2020) Prithvi Moharana et al.   INORGANIC CHEMISTRY COMMUNICATIONS

Toward Multi-Targeted Platinum and Ruthenium Drugs—A New Paradigm in Cancer Drug Treatment Regimens?

(2019) Reece G. Kenny et al.   CHEMICAL REVIEWS

Artemisinin-(Iso)Quinoline Hybrids by C-H Activation and Click Chemistry: Combating Multidrug-Resistant Malaria

(2019) Aysun Çapcı et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New designs for phototherapeutic transition metal complexes

(2019) Peter J. Sadler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Platinum Complexes: A Big Step Forward for Effective Antitumor Compounds

(2019) Stéphane Bellemin-Laponnaz   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Structure–activity relationships for ruthenium and osmium anticancer agents – towards clinical development

(2018) Samuel M. Meier-Menches et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of Artemisinin-Derived Dimers, Trimers and Dendrimers: Investigation of Their Antimalarial and Antiviral Activities Including Putative Mechanisms of Action

(2018) Tony Fröhlich et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organometallic Conjugates of the Drug Sulfadoxine for Combatting Antimicrobial Resistance

(2018) Prinessa Chellan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Design of prospective antiparasitic metal-based compounds including selected organometallic cores

(2018) D. Gambino et al.   INORGANICA CHIMICA ACTA

Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433

(2018) Susan Monro et al.   CHEMICAL REVIEWS

Metal Drugs and the Anticancer Immune Response

(2018) Bernhard Englinger et al.   CHEMICAL REVIEWS

Metal Compounds against Neglected Tropical Diseases

(2018) Yih Ching Ong et al.   CHEMICAL REVIEWS

Evaluation of PTA-derived ruthenium(II) and iridium(III) quinoline complexes against chloroquine-sensitive and resistant strains of the Plasmodium falciparum malaria parasite

(2018) Tameryn Stringer et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Redox-Active Metal Complexes for Anticancer Therapy

(2017) Pingyu Zhang et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

A pyrazine amide – 4-aminoquinoline hybrid and its rhodium and iridium pentamethylcyclopentadienyl complexes; evaluation of anti-mycobacterial and anti-plasmodial activities

(2017) Erik Ekengard et al.   Journal of the Mexican Chemical Society

Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action

(2017) Yin Kwan Wong et al.   MEDICINAL RESEARCH REVIEWS

Platinum-based drugs: past, present and future

(2016) Shahana Dilruba et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Pentamethylcyclopentadienyl-rhodium and iridium complexes containing (N^N and N^O) bound chloroquine analogue ligands: synthesis, characterization and antimalarial properties

(2016) Erik Ekengard et al.   DALTON TRANSACTIONS

Large-scale production of Plasmodium falciparum gametocytes for malaria drug discovery

(2016) Sandra Duffy et al.   Nature Protocols

Ferrocifen type anti cancer drugs

(2015) Gérard Jaouen et al.   CHEMICAL SOCIETY REVIEWS

Polyamine quinoline rhodium complexes: synthesis and pharmacological evaluation as antiparasitic agents against Plasmodium falciparum and Trichomonas vaginalis

(2015) Tameryn Stringer et al.   DALTON TRANSACTIONS

Improved reaction conditions for the synthesis of new NKP-1339 derivatives and preliminary investigations on their anticancer potential

(2015) P.-S. Kuhn et al.   DALTON TRANSACTIONS

Half-sandwich rhodium(III) transfer hydrogenation catalysts: Reduction of NAD + and pyruvate, and antiproliferative activity

(2015) Joan J. Soldevila-Barreda et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Organoiridium Complexes: Anticancer Agents and Catalysts

(2014) Zhe Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

(2014) Suzanne Leijen et al.   INVESTIGATIONAL NEW DRUGS

PlasmodiumfalciparumClearance Is Rapid and Pitting Independent in Immune Malian Children Treated With Artesunate for Malaria

(2014) Papa Alioune Ndour et al.   JOURNAL OF INFECTIOUS DISEASES

NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application

(2014) Robert Trondl et al.   Chemical Science

The Ferroquine Antimalarial Conundrum: Redox Activation and Reinvasion Inhibition

(2013) Faustine Dubar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Exploration of the medical periodic table: towards new targets

(2013) Nicolas P. E. Barry et al.   CHEMICAL COMMUNICATIONS

Synthesis and evaluation of new polynuclear organometallic Ru(ii), Rh(iii) and Ir(iii) pyridyl ester complexes as in vitro antiparasitic and antitumor agents

(2013) Prinessa Chellan et al.   DALTON TRANSACTIONS

Identification of inhibitors of Plasmodium falciparum gametocyte development

(2013) Sandra Duffy et al.   MALARIA JOURNAL

Synthesis and Cytotoxicity of Novel 10-Substituted Dihydroartemisinin Derivatives Containing N-Arylphenyl-ethenesulfonamide Groups

(2013) Yajing Liu et al.   MOLECULES

The antimalarial ferroquine: from bench to clinic

(2013) C. Biot et al.   Parasite

Development and Optimization of a Novel 384-Well Anti-Malarial Imaging Assay Validated for High-Throughput Screening

(2012) Sandra Duffy et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Designing organometallic compounds for catalysis and therapy

(2012) Anna Louisa Noffke et al.   CHEMICAL COMMUNICATIONS

Perspectives on what ruthenium-based compounds could offer in the development of potential antiparasitic drugs

(2012) Dinorah Gambino et al.   INORGANICA CHIMICA ACTA

Effects of Antimalarial Molecules on the Gametocyte Stage of Plasmodium falciparum: The Debate

(2012) Odile Dechy-Cabaret et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antimalarial Activity of Pyrroloiminoquinones from the Australian Marine Sponge Zyzzya sp.

(2012) Rohan A. Davis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bioorganometallic Compounds with Antimalarial Targets: Inhibiting Hemozoin Formation

(2012) Maribel Navarro et al.   ORGANOMETALLICS

Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug

(2011) Maria P. Crespo-Ortiz et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Approaching tumour therapy beyond platinum drugs

(2011) A. Bergamo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Organometallic Half-Sandwich Iridium Anticancer Complexes

(2011) Zhe Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue

(2011) S. H. Adjalley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pathogenesis of Plasmodium falciparum malaria in humans: insights from splenic physiology

(2010) P. A. Buffet et al.   BLOOD

Pharmacokinetics of a novel anticancer ruthenium complex (KP1019, FFC14A) in a phase I dose-escalation study

(2009) Frederike Lentz et al.   ANTI-CANCER DRUGS

Discovery, mechanisms of action and combination therapy of artemisinin

(2009) Liwang Cui et al.   Expert Review of Anti-Infective Therapy

In Vitro Activity of Ferroquine Is Independent of Polymorphisms in Transport Protein Genes Implicated in Quinoline Resistance in Plasmodium falciparum

(2008) M. Henry et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients

(2008) Christian G. Hartinger et al.   CHEMISTRY & BIODIVERSITY

The Hydrolysis Mechanism of the Anticancer Ruthenium Drugs NAMI-A and ICR Investigated by DFT−PCM Calculations

(2008) Attilio V. Vargiu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Influence of the anionic ligands on the anticancer activity of Ru(II)–dmso complexes: Kinetics of aquation and in vitro cytotoxicity of new dicarboxylate compounds in comparison with their chloride precursors

(2007) Ioannis Bratsos et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Electron-transfer activated metal-based anticancer drugs

(2006) Erwin Reisner et al.   INORGANICA CHIMICA ACTA