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Title
Role of Hypoxia Inducible Factor-1α in Alzheimer’s Disease
Authors
Keywords
-
Journal
JOURNAL OF ALZHEIMERS DISEASE
Volume -, Issue -, Pages 1-13
Publisher
IOS Press
Online
2021-02-20
DOI
10.3233/jad-201448
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Note: Only part of the references are listed.- “Amyloid‐beta accumulation cycle” as a prevention and/or therapy target for Alzheimer's disease
- (2020) Chinthalapally V. Rao et al. AGING CELL
- Amyloid-β, tau, and the cholinergic system in Alzheimer’s disease: seeking direction in a tangle of clues
- (2020) Alireza Majdi et al. REVIEWS IN THE NEUROSCIENCES
- Inflammation in Neurological Disorders: The Thin Boundary Between Brain and Periphery
- (2020) Carlo Cervellati et al. ANTIOXIDANTS & REDOX SIGNALING
- Alzheimer’s disease beyond amyloid: Can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery?
- (2020) Kevin Mullane et al. BIOCHEMICAL PHARMACOLOGY
- Synergy between amyloid-β and tau in Alzheimer’s disease
- (2020) Marc Aurel Busche et al. NATURE NEUROSCIENCE
- Characterization of a new molecule capable of inhibiting several steps of the amyloid cascade in Alzheimer's disease
- (2020) Christian Peters et al. NEUROBIOLOGY OF DISEASE
- Challenges and Opportunities of Deferoxamine Delivery for Treatment of Alzheimer’s Disease, Parkinson’s Disease, and Intracerebral Hemorrhage
- (2020) Amy Corbin Farr et al. MOLECULAR PHARMACEUTICS
- Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
- (2019) D. Allan Butterfield et al. NATURE REVIEWS NEUROSCIENCE
- Microglia-mediated neuroinflammation in neurodegenerative diseases
- (2019) Charannya Sozheesvari Subhramanyam et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease
- (2019) Sung Hoon Baik et al. Cell Metabolism
- The Role of a Neurovascular Signaling Pathway Involving Hypoxia-Inducible Factor and Notch in the Function of the Central Nervous System
- (2019) Seunghee Kim et al. Biomolecules & Therapeutics
- In vivo characterization of functional states of cortical microglia during peripheral inflammation
- (2019) Karin Riester et al. BRAIN BEHAVIOR AND IMMUNITY
- Amyloid-β as a Blood Biomarker for Alzheimer’s Disease: A Review of Recent Literature
- (2019) Xiaoni Wang et al. JOURNAL OF ALZHEIMERS DISEASE
- Alzheimer’s Disease and Parkinson’s Disease: A Nutritional Toxicology Perspective of the Impact of Oxidative Stress, Mitochondrial Dysfunction, Nutrigenomics and Environmental Chemicals
- (2019) Aayushi Agnihotri et al. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
- Neuroinflammation in Huntington’s Disease: New Insights with 11C-PBR28 PET/MRI
- (2018) Cristina Lois et al. ACS Chemical Neuroscience
- Late neuroprogenitors contribute to normal retinal vascular development in a Hif2a-dependent manner
- (2018) Enrico Cristante et al. DEVELOPMENT
- Alzheimer’s Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies—Gains from AIBL and DIAN Cohort Studies
- (2018) Ralph N. Martins et al. JOURNAL OF ALZHEIMERS DISEASE
- Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer’s Disease
- (2018) D. Allan Butterfield et al. JOURNAL OF ALZHEIMERS DISEASE
- Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease
- (2018) Géraldine Gelders et al. Journal of Immunology Research
- Uncoupled Endothelial Nitric Oxide Synthase Enhances p-Tau in Chronic Traumatic Encephalopathy Mouse Model
- (2018) Nara Shin et al. ANTIOXIDANTS & REDOX SIGNALING
- Chronic Intermittent Hypoxia/Reoxygenation Facilitate Amyloid-β Generation in Mice
- (2018) Satomi Shiota et al. JOURNAL OF ALZHEIMERS DISEASE
- Inflammation: the link between comorbidities, genetics, and Alzheimer’s disease
- (2018) Estella A. Newcombe et al. Journal of Neuroinflammation
- Understanding the Role of Hypoxia Inducible Factor During Neurodegeneration for New Therapeutics Opportunities
- (2018) Amalia Merelli et al. Current Neuropharmacology
- Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of alzheimer disease and other selected age-related neurodegenerative disorders
- (2017) Fabio Di Domenico et al. FREE RADICAL BIOLOGY AND MEDICINE
- Hypoxia/ischemia activate processing of Amyloid Precursor Protein: impact of vascular dysfunction in the pathogenesis of Alzheimer's disease
- (2017) Antero Salminen et al. JOURNAL OF NEUROCHEMISTRY
- Α-synuclein induces microglial cell migration through stimulating HIF-1α accumulation
- (2017) Hongfei Qiao et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Clinical significance of changes in serum neuroglobin and HIF-1α concentrations during the early-phase of acute ischemic stroke
- (2017) Lixia Xue et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer's disease brain
- (2017) Nona Abolhassani et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Intranasal Lactoferrin Enhances α-Secretase-Dependent Amyloid Precursor Protein Processing via the ERK1/2-CREB and HIF-1α Pathways in an Alzheimer’s Disease Mouse Model
- (2017) Chuang Guo et al. NEUROPSYCHOPHARMACOLOGY
- Hypoxia-inducible factor-1 alpha is involved in RIP-induced necroptosis caused by in vitro and in vivo ischemic brain injury
- (2017) Xiao-Sa Yang et al. Scientific Reports
- Chronic hypoxia facilitates Alzheimer's disease through demethylation of γ-secretase by downregulating DNA methyltransferase 3b
- (2016) Hui Liu et al. Alzheimers & Dementia
- Molecular mechanism of prion-like tau-induced neurodegeneration
- (2016) Alejandra D. Alonso et al. Alzheimers & Dementia
- Hypoxia-inducible factor 3 biology: complexities and emerging themes
- (2016) Cunming Duan AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The hypoxic tumor microenvironment: A driving force for breast cancer progression
- (2016) Gregg L. Semenza BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The Role of Hypoxia-Inducible Factor 1 in Mild Cognitive Impairment
- (2016) Osigbemhe Iyalomhe et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Glucose Transporters in Brain: In Health and in Alzheimer’s Disease
- (2016) Leszek Szablewski JOURNAL OF ALZHEIMERS DISEASE
- Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders
- (2016) Md. Torequl Islam NEUROLOGICAL RESEARCH
- Microglia–blood vessel interactions: a double-edged sword in brain pathologies
- (2015) Nevenka Dudvarski Stankovic et al. ACTA NEUROPATHOLOGICA
- Dose-specific effect of simvastatin on hypoxia-induced HIF-1α and BACE expression in Alzheimer’s disease cybrid cells
- (2015) Jin-Heon Jeong et al. BMC Neurology
- Intranasal deferoxamine engages multiple pathways to decrease memory loss in the APP/PS1 model of amyloid accumulation
- (2015) Jared M. Fine et al. NEUROSCIENCE LETTERS
- Intranasal deferoxamine attenuates synapse loss via up-regulating the P38/HIF-1α pathway on the brain of APP/PS1 transgenic mice
- (2015) Chuang Guo et al. Frontiers in Aging Neuroscience
- Hypoxia Affects Neprilysin Expression Through Caspase Activation and an APP Intracellular Domain-dependent Mechanism
- (2015) Caroline Kerridge et al. Frontiers in Neuroscience
- The Novel Multi-Target Iron Chelator, M30 Modulates HIF-1α-Related Glycolytic Genes and Insulin Signaling Pathway in the Frontal Cortex of APP/PS1 Alzheimer’s Disease Mice
- (2014) Danit Mechlovich et al. Current Alzheimer Research
- A viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis
- (2014) Yimin Sun et al. Neural Regeneration Research
- Hypoxia-inducible factor-1α upregulation in microglia following hypoxia protects against ischemia-induced cerebral infarction
- (2014) Tao Huang et al. NEUROREPORT
- Hypoxia Induces Autophagic Cell Death through Hypoxia-Inducible Factor 1α in Microglia
- (2014) Zhao Yang et al. PLoS One
- Amyloid-β and Tau
- (2014) George S. Bloom JAMA Neurology
- Structural and functional analysis of amphioxus HIFα reveals ancient features of the HIFα family
- (2013) Shan Gao et al. FASEB JOURNAL
- Evaluation of hypoxia inducible factor expression in inflammatory and neurodegenerative brain models
- (2013) Maria Luisa de Lemos et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Allosteric inhibition of hypoxia inducible factor-2 with small molecules
- (2013) Thomas H Scheuermann et al. Nature Chemical Biology
- The Novel Multi-Target Iron Chelating-Radical Scavenging Compound M30 Possesses Beneficial Effects on Major Hallmarks of Alzheimer's Disease
- (2012) Lana Kupershmidt et al. ANTIOXIDANTS & REDOX SIGNALING
- The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
- (2012) Iryna Benilova et al. NATURE NEUROSCIENCE
- Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain
- (2012) Chuang Guo et al. NEUROCHEMISTRY INTERNATIONAL
- Nuclear and mitochondrial DNA oxidation in Alzheimer's disease
- (2011) Renato X. Santos et al. FREE RADICAL RESEARCH
- The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis
- (2011) Jie Zhao et al. Journal of Neuroinflammation
- Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils
- (2011) Jan Bieschke et al. Nature Chemical Biology
- Oxidative Stress and Hypoxia Contribute to Alzheimer's Disease Pathogenesis: Two Sides of the Same Coin
- (2011) Michela Guglielmotto et al. TheScientificWorldJOURNAL
- Melatonin reduces hippocampal β-amyloid generation in rats exposed to chronic intermittent hypoxia
- (2010) Kwong-Man Ng et al. BRAIN RESEARCH
- Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
- (2010) Lars M. Ittner et al. CELL
- Fyn-Tau-Amyloid: A Toxic Triad
- (2010) Christian Haass et al. CELL
- Amyloid β oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors
- (2010) Elena Alberdi et al. CELL CALCIUM
- Up-Regulation of Hypoxia-Inducible Factor (HIF)-1α and HIF-Target Genes in Cortical Neurons by the Novel Multifunctional Iron Chelator Anti-Alzheimer Drug, M30
- (2010) Y. Avramovich-Tirosh et al. Current Alzheimer Research
- Presenilin-1 regulates induction of hypoxia inducible factor-1α: altered activation by a mutation associated with familial Alzheimer's disease
- (2010) Rita De Gasperi et al. Molecular Neurodegeneration
- Contribution of hypoxia to Alzheimer’s disease: is HIF-1α a mediator of neurodegeneration?
- (2009) O. O. Ogunshola et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The induction of HIF-1 reduces astrocyte activation by amyloid beta peptide
- (2009) David Schubert et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Hypoxia-inducible factor 1: a new hope to counteract neurodegeneration?
- (2009) Sónia C. Correia et al. JOURNAL OF NEUROCHEMISTRY
- Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease
- (2008) Ying Liu et al. FEBS LETTERS
- The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α
- (2008) Michela Guglielmotto et al. JOURNAL OF NEUROCHEMISTRY
- Hypoxia increases Aβ generation by altering β- and γ-cleavage of APP
- (2007) Liang Li et al. NEUROBIOLOGY OF AGING
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