Arsenite induces ferroptosis in the neuronal cells via activation of ferritinophagy

Arsenite induces testicular oxidative stress in vivo and in vitro leading to ferroptosis

(2020) Pan Meng et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Heterozygous disruption of beclin 1 mitigates arsenite-induced neurobehavioral deficits via reshaping gut microbiota-brain axis

(2020) Yujia Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Ferroptosis and Its Potential Role in Human Diseases

(2020) Chu Han et al.   Frontiers in Pharmacology

Using the Metabolome to Understand the Mechanisms Linking Chronic Arsenic Exposure to Microglia Activation, and Learning and Memory Impairment

(2020) Rui-Yuan Zhang et al.   NEUROTOXICITY RESEARCH

NCOA4-Mediated Ferritinophagy: A Potential Link to Neurodegeneration

(2019) Maria Quiles del Rey et al.   Frontiers in Neuroscience

Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis

(2019) Guo-Qing Chen et al.   CELL DEATH AND DIFFERENTIATION

Arsenic-induced neurotoxicity: a mechanistic appraisal

(2019) Carla Garza-Lombó et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

The chemical basis of ferroptosis

(2019) Marcus Conrad et al.   Nature Chemical Biology

Arsenic induces pancreatic dysfunction and ferroptosis via mitochondrial ROS-autophagy-lysosomal pathway

(2019) Sen Wei et al.   JOURNAL OF HAZARDOUS MATERIALS

In vivo evaluation of arsenic-associated behavioral and biochemical alterations in F0 and F1 mice

(2019) Sheta Biswas et al.   CHEMOSPHERE

GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues

(2018) Matilde Maiorino et al.   ANTIOXIDANTS & REDOX SIGNALING

Ameliorative effects of selenium on arsenic-induced cytotoxicity in PC12 cells via modulating autophagy/apoptosis

(2018) Md. Mostafizur Rahman et al.   CHEMOSPHERE

Sneaky Entry of IFNγ Through Arsenic-Induced Leaky Blood–Brain Barrier Reduces CD200 Expression by Microglial pro-Inflammatory Cytokine

(2018) Vikas Singh et al.   MOLECULAR NEUROBIOLOGY

Ferroptosis is newly characterized form of neuronal cell death in response to arsenite exposure

(2018) Qianghu Tang et al.   NEUROTOXICOLOGY

m6A demethylase FTO regulates dopaminergic neurotransmission deficits caused by arsenite

(2018) LuLu Bai et al.   TOXICOLOGICAL SCIENCES

Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis

(2018) Shashank Masaldan et al.   Redox Biology

Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood–brain barrier’s tight junction proteins

(2018) Ram Kumar Manthari et al.   ARCHIVES OF TOXICOLOGY

Novel antitumor compound optimized from natural saponin Albiziabioside A induced caspase-dependent apoptosis and ferroptosis as a p53 activator through the mitochondrial pathway

(2018) Gaofei Wei et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Striking while the iron is hot: Iron metabolism and Ferroptosis in neurodegeneration

(2018) Shashank Masaldan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Arsenic-Induced Autophagy in the Developing Mouse Cerebellum: Involvement of the Blood–Brain Barrier’s Tight-Junction Proteins and the PI3K–Akt–mTOR Signaling Pathway

(2018) Ram Kumar Manthari et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ferritinophagy/ferroptosis: Iron-related newcomers in human diseases

(2018) Mingzhu Tang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway

(2018) Tianming Qiu et al.   Cell Death & Disease

Role of pigment epithelium-derived factor (PEDF) on arsenic-induced neuronal apoptosis

(2018) Wei Zhang et al.   CHEMOSPHERE

Ferroptosis and Its Role in Diverse Brain Diseases

(2018) Abigail Weiland et al.   MOLECULAR NEUROBIOLOGY

Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis

(2017) Marietta Zille et al.   STROKE

From the Cover: Arsenic Induces Hippocampal Neuronal Apoptosis and Cognitive Impairments via an Up-Regulated BMP2/Smad-Dependent Reduced BDNF/TrkB Signaling in Rats

(2017) Rukmani Pandey et al.   TOXICOLOGICAL SCIENCES

Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration

(2017) William Sealy Hambright et al.   Redox Biology

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Postnatal arsenic exposure and attention impairment in school children

(2016) Miguel Rodríguez-Barranco et al.   CORTEX

From the Cover: Arsenic Induces Accumulation of α-Synuclein: Implications for Synucleinopathies and Neurodegeneration

(2016) Aram B. Cholanians et al.   TOXICOLOGICAL SCIENCES

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

NCOA4 Deficiency Impairs Systemic Iron Homeostasis

(2016) Roberto Bellelli et al.   Cell Reports

Mitochondrial oxidative stress and dysfunction in arsenic neurotoxicity: A review

(2015) Chandra Prakash et al.   JOURNAL OF APPLIED TOXICOLOGY

Iron and Neurodegeneration: Is Ferritinophagy the Link?

(2015) Giorgio Biasiotto et al.   MOLECULAR NEUROBIOLOGY

Role of autophagy in arsenite-induced neurotoxicity: The involvement of α-synuclein

(2015) Yu-Chun Teng et al.   TOXICOLOGY LETTERS

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

(2014) Rachid Skouta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Cellular protection using Flt3 and PI3Kα inhibitors demonstrates multiple mechanisms of oxidative glutamate toxicity

(2014) Yunyi Kang et al.   Nature Communications

The Developmental Neurotoxicity of Arsenic: Cognitive and Behavioral Consequences of Early Life Exposure

(2014) Molly Tolins et al.   Annals of Global Health

A review of arsenic presence in China drinking water

(2013) Jing He et al.   JOURNAL OF HYDROLOGY

Systemic Iron Homeostasis

(2013) Tomas Ganz   PHYSIOLOGICAL REVIEWS

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Effects of arsenite in astrocytes on neuronal signaling transduction

(2012) Yan Wang et al.   TOXICOLOGY

Effects of arsenic exposure from drinking water on spatial memory, ultra-structures and NMDAR gene expression of hippocampus in rats

(2008) Jiao-hua Luo et al.   TOXICOLOGY LETTERS