Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway

Autophagy fails to prevent glucose deprivation/glucose reintroduction-induced neuronal death due to calpain-mediated lysosomal dysfunction in cortical neurons

(2017) Cristian Gerónimo-Olvera et al.   Cell Death & Disease

CdSe/ZnS quantum dots induce hepatocyte pyroptosis and liver inflammation via NLRP3 inflammasome activation

(2016) Yonghui Lu et al.   BIOMATERIALS

Innate Immunity and Inflammation in NAFLD/NASH

(2016) Marco Arrese et al.   DIGESTIVE DISEASES AND SCIENCES

Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer

(2016) Anna M. Schläfli et al.   Oncotarget

An integrated metabonomic and proteomic study on Kidney-Yin Deficiency Syndrome patients with diabetes mellitus in China

(2015) Ning Jiang et al.   ACTA PHARMACOLOGICA SINICA

Cathepsins in heart disease–chewing on the heartache?

(2015) Jordan Blondelle et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Effects of Arsenite Exposure during Fetal Development on Energy Metabolism and Susceptibility to Diet-Induced Fatty Liver Disease in Male Mice

(2015) Eric J. Ditzel et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

NAFLD: A multisystem disease

(2015) Christopher D. Byrne et al.   JOURNAL OF HEPATOLOGY

LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells

(2015) Peidu Jiang et al.   METHODS

The role of immune mechanisms in alcoholic and nonalcoholic steatohepatitis: a 2015 update

(2015) Salvatore Sutti et al.   Expert Review of Gastroenterology & Hepatology

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

(2014) Alvin Lu et al.   CELL

Sodium arsenite induces ROS-dependent autophagic cell death in pancreatic β-cells

(2014) Xue-Xin Zhu et al.   FOOD AND CHEMICAL TOXICOLOGY

NLRP3 inflammasome activation is required for fibrosis development in NAFLD

(2014) Alexander Wree et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

(2013) Alexander Wree et al.   HEPATOLOGY

Immune and inflammatory pathways in NASH

(2013) Michal Ganz et al.   Hepatology International

Autophagy in the immune system

(2013) Daniel J. Puleston et al.   IMMUNOLOGY

Cathepsin B Contributes to Autophagy-related 7 (Atg7)-induced Nod-like Receptor 3 (NLRP3)-dependent Proinflammatory Response and Aggravates Lipotoxicity in Rat Insulinoma Cell Line

(2013) Shali Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arsenic Inhibits Autophagic Flux, Activating the Nrf2-Keap1 Pathway in a p62-Dependent Manner

(2013) A. Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

Groundwater Arsenic Contamination Throughout China

(2013) L. Rodriguez-Lado et al.   SCIENCE

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

(2012) Naga Chalasani et al.   HEPATOLOGY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

The potential usefulness of taurine on diabetes mellitus and its complications

(2011) Takashi Ito et al.   AMINO ACIDS

Lycium barbarum (Goji Berry) extracts and its taurine component inhibit PPAR-γ-dependent gene transcription in human retinal pigment epithelial cells: Possible implications for diabetic retinopathy treatment

(2011) M.K. Song et al.   BIOCHEMICAL PHARMACOLOGY

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells

(2011) Timea Csak et al.   HEPATOLOGY

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

Chronic subhepatotoxic exposure to arsenic enhances hepatic injury caused by high fat diet in mice

(2011) Min Tan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Guidelines for the diagnosis and management of nonalcoholic fatty liver disease: Update 2010

(2010) Jian Gao FAN et al.   Journal of Digestive Diseases

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet

(2009) Baukje de Roos et al.   PROTEOMICS