Recent advances in the therapeutic application of short-chain fatty acids (SCFAs): An updated review

Short chain fatty acids produced by colonizing intestinal commensal bacterial interaction with expressed breast milk are anti-inflammatory in human immature enterocytes

(2020) Nan Zheng et al.   PLoS One

Effects of Gut Microbiome and Short-Chain Fatty Acids (SCFAs) on Finishing Weight of Meat Rabbits

(2020) Shaoming Fang et al.   Frontiers in Microbiology

Exploring the Molecular Mechanisms Underlying the Protective Effects of Microbial SCFAs on Intestinal Tolerance and Food Allergy

(2020) Maik Luu et al.   Frontiers in Immunology

Oral neonatal antibiotic treatment perturbs gut microbiota and aggravates central nervous system autoimmunity in Dark Agouti rats

(2019) Suzana Stanisavljević et al.   Scientific Reports

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases

(2019) Serena Sanna et al.   NATURE GENETICS

Immunomodulatory potential of gut microbiome-derived short-chain fatty acids (SCFAs)

(2019) Weronika Ratajczak et al.   ACTA BIOCHIMICA POLONICA

Prebiotics from acorn and sago prevent high-fat-diet-induced insulin resistance via microbiome–gut–brain axis modulation

(2019) Shokouh Ahmadi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Corrigendum: Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases

(2019) Daniela Parada Venegas et al.   Frontiers in Immunology

Stable isotope labeling combined with liquid chromatography-tandem mass spectrometry for comprehensive analysis of short-chain fatty acids

(2019) Jie Zheng et al.   ANALYTICA CHIMICA ACTA

Fecal microbiota transplantation alleviated Alzheimer’s disease-like pathogenesis in APP/PS1 transgenic mice

(2019) Jing Sun et al.   Translational Psychiatry

Butyrate suppresses demyelination and enhances remyelination

(2019) Tong Chen et al.   Journal of Neuroinflammation

Dietary SCFAs, IL-22, and GFAP: The Three Musketeers in the Gut–Neuro–Immune Network in Type 1 Diabetes

(2019) Abhirup Jayasimhan et al.   Frontiers in Immunology

Short-chain fatty acids and microbiota metabolites attenuate ghrelin receptor signaling

(2019) Cristina Torres-Fuentes et al.   FASEB JOURNAL

Enhanced bioproduction of short-chain fatty acids from waste activated sludge by potassium ferrate pretreatment

(2018) Lin Li et al.   CHEMICAL ENGINEERING JOURNAL

Pro- and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells

(2018) Meng Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Short-chain fatty acids administration is protective in colitis-associated colorectal cancer development

(2018) Yun Tian et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Low amounts of dietary fibre increase in vitro production of short-chain fatty acids without changing human colonic microbiota structure

(2018) Daisuke Sasaki et al.   Scientific Reports

Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects

(2018) Rudimar L. Frozza et al.   Frontiers in Neuroscience

Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain-gut axis alterations

(2018) Marcel van de Wouw et al.   JOURNAL OF PHYSIOLOGY-LONDON

Microbiome—The Missing Link in the Gut-Brain Axis: Focus on Its Role in Gastrointestinal and Mental Health

(2018) Karolina Skonieczna-Żydecka et al.   Journal of Clinical Medicine

Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms

(2017) Lap Ho et al.   Expert Review of Neurotherapeutics

Prebiotics and Inflammatory Bowel Disease

(2017) Heather E. Rasmussen et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Altered Gut Microbiota in a Mouse Model of Alzheimer’s Disease

(2017) Ling Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Probiotics are a good choice in remission of inflammatory bowel diseases: A meta analysis and systematic review

(2017) Mahboube Ganji-Arjenaki et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Microbial-Derived Butyrate Promotes Epithelial Barrier Function through IL-10 Receptor–Dependent Repression of Claudin-2

(2017) Leon Zheng et al.   JOURNAL OF IMMUNOLOGY

Increasing acetyl-CoA metabolism attenuates injury and alters spinal cord lipid content in mice subjected to experimental autoimmune encephalomyelitis

(2017) Amber C. Chevalier et al.   JOURNAL OF NEUROCHEMISTRY

Role of short-chain fatty acids in colonic inflammation, carcinogenesis, and mucosal protection and healing

(2017) Christina M. van der Beek et al.   NUTRITION REVIEWS

Microbiota-Derived Short-Chain Fatty Acids Modulate Expression of Campylobacter jejuni Determinants Required for Commensalism and Virulence

(2017) Paul M. Luethy et al.   mBio

Short Chain Fatty Acids in the Colon and Peripheral Tissues: A Focus on Butyrate, Colon Cancer, Obesity and Insulin Resistance

(2017) Sean McNabney et al.   Nutrients

Age Drives Distortion of Brain Metabolic, Vascular and Cognitive Functions, and the Gut Microbiome

(2017) Jared D. Hoffman et al.   Frontiers in Aging Neuroscience

Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms

(2017) Lap Ho et al.   Expert Review of Neurotherapeutics

Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial

(2017) Emanuel E. Canfora et al.   Scientific Reports

Longitudinal Patterns of Glycemic Control and Blood Pressure in Pregnant Women with Type 1 Diabetes Mellitus: Phenotypes from Functional Data Analysis

(2016) Dan Li et al.   AMERICAN JOURNAL OF PERINATOLOGY

Glucose- and glycaemic factor-lowering effects of probiotics on diabetes: a meta-analysis of randomised placebo-controlled trials

(2016) Jing Sun et al.   BRITISH JOURNAL OF NUTRITION

Gut Microbiota Dysbiosis as Risk and Premorbid Factors of IBD and IBS Along the Childhood–Adulthood Transition

(2016) Lorenza Putignani et al.   INFLAMMATORY BOWEL DISEASES

Systemic availability and metabolism of colonic-derived short-chain fatty acids in healthy subjects: a stable isotope study

(2016) Eef Boets et al.   JOURNAL OF PHYSIOLOGY-LONDON

The role of Gut Microbiota in the development of obesity and Diabetes

(2016) Othman A. Baothman et al.   Lipids in Health and Disease

Alterations of the human gut microbiome in multiple sclerosis

(2016) Sushrut Jangi et al.   Nature Communications

The Dual Role of Neutrophils in Inflammatory Bowel Diseases

(2016) Odile Wéra et al.   Journal of Clinical Medicine

The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging

(2015) Michael E. Walsh et al.   AGING CELL

SCFAs Take a Toll En Route to Metabolic Syndrome

(2015) André Marette et al.   Cell Metabolism

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine

(2015) Aiden Haghikia et al.   IMMUNITY

Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats

(2015) Xu Zhang et al.   Scientific Reports

Biological significance of short-chain fatty acid metabolism by the intestinal microbiome

(2014) Elena Puertollano et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Evidence for the Gut Microbiota Short-Chain Fatty Acids as Key Pathophysiological Molecules Improving Diabetes

(2014) Alessandra Puddu et al.   MEDIATORS OF INFLAMMATION

The Gastrointestinal Tract Microbiome and Potential Link to Alzheimer’s Disease

(2014) James M. Hill et al.   Frontiers in Neurology

Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion

(2013) Hariom Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

The intestinal fatty acid propionate inhibitsSalmonellainvasion through the post-translational control of HilD

(2013) Chien-Che Hung et al.   MOLECULAR MICROBIOLOGY

The Expression of stlA in Photorhabdus luminescens Is Controlled by Nutrient Limitation

(2013) Lea Lango-Scholey et al.   PLoS One

Butyrate increases IL-23 production by stimulated dendritic cells

(2012) Bradford E. Berndt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells

(2012) Mary A. Zimmerman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial

(2012) Rubhana Raqib et al.   BMC INFECTIOUS DISEASES

Elevated Fecal Short Chain Fatty Acid and Ammonia Concentrations in Children with Autism Spectrum Disorder

(2012) Lv Wang et al.   DIGESTIVE DISEASES AND SCIENCES

The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates

(2012) Erwin G Zoetendal et al.   ISME Journal

Bacteria, Colonic Fermentation, and Gastrointestinal Health

(2012) George T. Macfarlane et al.   JOURNAL OF AOAC INTERNATIONAL

Fatty Acids Regulate Stress Resistance and Virulence Factor Production for Listeria monocytogenes

(2012) Y. Sun et al.   JOURNAL OF BACTERIOLOGY

Investigation of the Listeria monocytogenes Scott A Acid Tolerance Response and Associated Physiological and Phenotypic Features via Whole Proteome Analysis

(2012) John P. Bowman et al.   JOURNAL OF PROTEOME RESEARCH

The health benefits of dietary fiber: Beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer

(2012) Melissa M. Kaczmarczyk et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Genomic variation landscape of the human gut microbiome

(2012) Siegfried Schloissnig et al.   NATURE

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms

(2012) Hua V. Lin et al.   PLoS One

Modulation of Antimicrobial Host Defense Peptide Gene Expression by Free Fatty Acids

(2012) Lakshmi T. Sunkara et al.   PLoS One

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Short chain fatty acids and their receptors: new metabolic targets

(2012) Brian T. Layden et al.   Translational Research

Stoichiometric and energetic analyses of non-photosynthetic CO2-fixation pathways to support synthetic biology strategies for production of fuels and chemicals

(2012) Alan G Fast et al.   Current Opinion in Chemical Engineering

Propionate. Anti-obesity and satiety enhancing factor?

(2011) Tulika Arora et al.   APPETITE

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

Carbohydrate metabolism in Bifidobacteria

(2011) Karina Pokusaeva et al.   Genes and Nutrition

Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives

(2011) M. Joossens et al.   GUT

Progress in genomics, metabolism and biotechnology of bifidobacteria

(2011) Michelle Cronin et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

The monocarboxylate transporter family-Role and regulation

(2011) Andrew P. Halestrap et al.   IUBMB LIFE

A review of practical Salmonella control measures in animal feed

(2011) F. T. Jones   JOURNAL OF APPLIED POULTRY RESEARCH

Salmonella spp. survival strategies within the host gastrointestinal tract

(2011) A. Alvarez-Ordonez et al.   MICROBIOLOGY-SGM

Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements

(2011) Alexander R. C. Wong et al.   MOLECULAR MICROBIOLOGY

Bifidobacteria can protect from enteropathogenic infection through production of acetate

(2011) Shinji Fukuda et al.   NATURE

Butyrate Enhances Disease Resistance of Chickens by Inducing Antimicrobial Host Defense Peptide Gene Expression

(2011) Lakshmi T. Sunkara et al.   PLoS One

Understanding the role of gut microbiome–host metabolic signal disruption in health and disease

(2011) Elaine Holmes et al.   TRENDS IN MICROBIOLOGY

Campylobacter control in poultry by current intervention measures ineffective: Urgent need for intensified fundamental research

(2011) David Hermans et al.   VETERINARY MICROBIOLOGY

Short chain fatty acids (propionic and hexanoic) decrease Staphylococcus aureus internalization into bovine mammary epithelial cells and modulate antimicrobial peptide expression

(2011) Nayeli Alva-Murillo et al.   VETERINARY MICROBIOLOGY

Regulation of Inflammation by Short Chain Fatty Acids

(2011) Marco A.R. Vinolo et al.   Nutrients

Transcriptomic and Phenotypic Responses of Listeria monocytogenes Strains Possessing Different Growth Efficiencies under Acidic Conditions

(2010) J. P. Bowman et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Activation of Motility by Sensing Short-Chain Fatty Acids via Two Steps in a Flagellar Gene Regulatory Cascade in EnterohemorrhagicEscherichia coli

(2010) Toru Tobe et al.   INFECTION AND IMMUNITY

Blockade of Dendritic Cell Development by Bacterial Fermentation Products Butyrate and Propionate through a Transporter (Slc5a8)-dependent Inhibition of Histone Deacetylases

(2010) Nagendra Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissecting thein VivoMetabolic Potential of Two Human Gut Acetogens

(2010) Federico E. Rey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARγ-related adipogenesis in the white adipose tissue of high-fat diet-fed mice

(2010) Evelyne M. Dewulf et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

Short-chain fatty acids and poly-β-hydroxyalkanoates: (New) Biocontrol agents for a sustainable animal production

(2009) Tom Defoirdt et al.   BIOTECHNOLOGY ADVANCES

Characterization of the expression of Salmonella Type III secretion system factor PrgI, SipA, SipB, SopE2, SpaO, and SptP in cultures and in mice

(2009) Hao Gong et al.   BMC MICROBIOLOGY

GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

(2009) M. Thangaraju et al.   CANCER RESEARCH

Short-chain fatty acids stimulate the migration of neutrophils to inflammatory sites

(2009) Marco A. R. Vinolo et al.   CLINICAL SCIENCE

Chemical Treatment of Animal Feed and Water for the Control of Salmonella

(2009) Andrew D. Wales et al.   Foodborne Pathogens and Disease

Prebiotics in Chronic Intestinal Inflammation

(2009) Mirjam A.C. Looijer–Van Langen et al.   INFLAMMATORY BOWEL DISEASES

Advances in enteropathogen control in poultry production

(2009) J.M. Cox et al.   JOURNAL OF APPLIED MICROBIOLOGY

Prebiotic oligosaccharides change the concentrations of short-chain fatty acids and the microbial population of mouse bowel

(2009) Xiao-dong Pan et al.   Journal of Zhejiang University-SCIENCE B

Regulation of virulence by butyrate sensing in enterohaemorrhagic Escherichia coli

(2009) N. Nakanishi et al.   MICROBIOLOGY-SGM

Differential effects of short-chain fatty acids and iron on expression of iha in Shiga-toxigenic Escherichia coli

(2009) S. Herold et al.   MICROBIOLOGY-SGM

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways

(2009) Michiko Aoyama et al.   NUTRITION

Butyric acid-based feed additives help protect broiler chickens from Salmonella Enteritidis infection

(2009) C. Fernandez-Rubio et al.   POULTRY SCIENCE

Butyrate protects Caco-2 cells from Campylobacter jejuni invasion and translocation

(2008) Kim Van Deun et al.   BRITISH JOURNAL OF NUTRITION

Formate Acts as a Diffusible Signal To Induce Salmonella Invasion

(2008) Y. Huang et al.   JOURNAL OF BACTERIOLOGY

PU.1 and bacterial metabolites regulate the human gene CAMP encoding antimicrobial peptide LL-37 in colon epithelial cells

(2008) Stefan Termén et al.   MOLECULAR IMMUNOLOGY

Coated fatty acids alter virulence properties of Salmonella Typhimurium and decrease intestinal colonization of pigs

(2008) F. Boyen et al.   VETERINARY MICROBIOLOGY

Gastrointestinal microbial ecology and the safety of our food supply as related to Salmonella1,2

(2007) T. R. Callaway et al.   JOURNAL OF ANIMAL SCIENCE