Growth differentiation factor 5 in cartilage and osteoarthritis: A possible therapeutic candidate
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Title
Growth differentiation factor 5 in cartilage and osteoarthritis: A possible therapeutic candidate
Authors
Keywords
-
Journal
CELL PROLIFERATION
Volume 54, Issue 3, Pages -
Publisher
Wiley
Online
2021-02-01
DOI
10.1111/cpr.12998
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Note: Only part of the references are listed.- Increasing the Medium Osmolarity Reduces the Inflammatory Status of Human OA Chondrocytes and Increases Their Responsiveness to GDF-5
- (2020) Tanja Mang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulation of Gdf5 expression in joint remodelling, repair and osteoarthritis
- (2020) Karolina Kania et al. Scientific Reports
- Evolutionary Selection and Constraint on Human Knee Chondrocyte Regulation Impacts Osteoarthritis Risk
- (2020) Daniel Richard et al. CELL
- Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex
- (2020) Tomas Malinauskas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interaction between GDF5 gene polymorphisms and environment factors increased the risk of knee osteoarthritis: a case–control study
- (2019) Sujie Zhang et al. BIOSCIENCE REPORTS
- Mechanisms of synovial joint and articular cartilage development
- (2019) Ryota Chijimatsu et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cells from a GDF5 origin produce zonal tendon‐to‐bone attachments following anterior cruciate ligament reconstruction
- (2019) Yusuke Hagiwara et al. Annals of the New York Academy of Sciences
- NF-κB Signaling Regulates Physiological and Pathological Chondrogenesis
- (2019) Eijiro Jimi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Impact of broad regulatory regions on Gdf5 expression and function in knee development and susceptibility to osteoarthritis
- (2018) Steven K Pregizer et al. ANNALS OF THE RHEUMATIC DISEASES
- MicroRNA-449a upregulation promotes chondrocyte extracellular matrix degradation in osteoarthritis
- (2018) Jianjun Wu et al. BIOMEDICINE & PHARMACOTHERAPY
- Molecular transport in articular cartilage — what have we learned from the past 50 years?
- (2018) Chris D. DiDomenico et al. Nature Reviews Rheumatology
- Bone morphogenetic proteins for articular cartilage regeneration
- (2018) Z.H. Deng et al. OSTEOARTHRITIS AND CARTILAGE
- Redox control of chondrocyte differentiation and chondrogenesis
- (2018) Yun Bai et al. FREE RADICAL BIOLOGY AND MEDICINE
- Ancient selection for derived alleles at a GDF5 enhancer influencing human growth and osteoarthritis risk
- (2017) Terence D Capellini et al. NATURE GENETICS
- Intra-articular therapy with recombinant human GDF5 arrests disease progression and stimulates cartilage repair in the rat medial meniscus transection (MMT) model of osteoarthritis
- (2017) W.R. Parrish et al. OSTEOARTHRITIS AND CARTILAGE
- Single nucleotide polymorphisms in DNA repair genes and putative cancer risk
- (2016) Beate Köberle et al. ARCHIVES OF TOXICOLOGY
- The cartilage extracellular matrix as a transient developmental scaffold for growth plate maturation
- (2016) James Melrose et al. MATRIX BIOLOGY
- Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis
- (2016) William H. Robinson et al. Nature Reviews Rheumatology
- Joint Development Involves a Continuous Influx of Gdf5-Positive Cells
- (2016) Yulia Shwartz et al. Cell Reports
- Heads, Shoulders, Elbows, Knees, and Toes: Modular Gdf5 Enhancers Control Different Joints in the Vertebrate Skeleton
- (2016) Hao Chen et al. PLoS Genetics
- GDF-5 can act as a context-dependent BMP-2 antagonist
- (2015) Uwe Klammert et al. BMC BIOLOGY
- The effective mode of growth and differentiation factor-5 in promoting the chondrogenic differentiation of adipose-derived stromal cells
- (2015) Changxu Han et al. CELL AND TISSUE BANKING
- Genetic contribution to osteoarthritis development
- (2015) John Loughlin CURRENT OPINION IN RHEUMATOLOGY
- Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation
- (2015) A. Ray et al. DEVELOPMENT
- A comprehensive meta-analysis of association between genetic variants of GDF5 and osteoarthritis of the knee, hip and hand
- (2015) Rui Zhang et al. INFLAMMATION RESEARCH
- Osteoarthritis
- (2015) S Glyn-Jones et al. LANCET
- Response of knee fibrocartilage to joint destabilization
- (2015) N.A. Dyment et al. OSTEOARTHRITIS AND CARTILAGE
- Regulation of α5 and αV Integrin Expression by GDF-5 and BMP-7 in Chondrocyte Differentiation and Osteoarthritis
- (2015) David Garciadiego-Cázares et al. PLoS One
- TGF-β1, GDF-5, and BMP-2 Stimulation Induces Chondrogenesis in Expanded Human Articular Chondrocytes and Marrow-Derived Stromal Cells
- (2015) Meghan K. Murphy et al. STEM CELLS
- Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells
- (2015) Alexandra Karystinou et al. ARTHRITIS RESEARCH & THERAPY
- Articular Cartilage: Structural and Developmental Intricacies and Questions
- (2015) Rebekah S. Decker et al. Current Osteoporosis Reports
- Association between GDF5 rs143383 polymorphism and knee osteoarthritis: an updated meta-analysis based on 23,995 subjects
- (2014) Feng Pan et al. BMC MUSCULOSKELETAL DISORDERS
- Repair of cartilage defects in BMSCs via CDMP1 gene transfection
- (2014) G. Wu et al. GENETICS AND MOLECULAR RESEARCH
- CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383
- (2014) Louise N. Reynard et al. HUMAN GENETICS
- GDF5 reduces MMP13 expression in human chondrocytes via DKK1 mediated canonical Wnt signaling inhibition
- (2014) L. Enochson et al. OSTEOARTHRITIS AND CARTILAGE
- Human Chondrocytes Respond Discordantly to the Protein Encoded by the Osteoarthritis Susceptibility Gene GDF5
- (2014) Madhushika Ratnayake et al. PLoS One
- Lineage Tracing of Resident Tendon Progenitor Cells during Growth and Natural Healing
- (2014) Nathaniel A. Dyment et al. PLoS One
- SOX11 contributes to the regulation of GDF5 in joint maintenance
- (2013) Akinori Kan et al. BMC DEVELOPMENTAL BIOLOGY
- Repairing cartilage defects with bone marrow mesenchymal stem cells induced by CDMP and TGF-β1
- (2013) Gang Wu et al. CELL AND TISSUE BANKING
- Regulatory mechanisms for the development of growth plate cartilage
- (2013) Toshimi Michigami CELLULAR AND MOLECULAR LIFE SCIENCES
- Growth Differentiation Factor-5 Enhances In Vitro Mesenchymal Stromal Cell Chondrogenesis and Hypertrophy
- (2013) Cynthia M. Coleman et al. STEM CELLS AND DEVELOPMENT
- The Identification of Trans-acting Factors That Regulate the Expression of GDF5 via the Osteoarthritis Susceptibility SNP rs143383
- (2013) Catherine M. Syddall et al. PLoS Genetics
- A rare variant in the osteoarthritis-associated locus GDF5 is functional and reveals a site that can be manipulated to modulate GDF5 expression
- (2012) Andrew W Dodd et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Genetic association analysis of GDF5 and ADAM12 for knee osteoarthritis
- (2012) Min-Ho Shin et al. JOINT BONE SPINE
- Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis
- (2012) Mary B. Goldring Therapeutic Advances in Musculoskeletal Disease
- Osteoarthritis susceptibility genes influence the association between hip morphology and osteoarthritis
- (2011) J. H. Waarsing et al. ARTHRITIS AND RHEUMATISM
- Genetic factors in OA pathogenesis
- (2011) Kay Chapman et al. BONE
- Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation
- (2011) Louise N. Reynard et al. HUMAN MOLECULAR GENETICS
- Human Mesenchymal Stem Cells Induced by Growth Differentiation Factor 5: An Improved Self-Assembly Tissue Engineering Method for Cartilage Repair
- (2011) Bo Zhang et al. TISSUE ENGINEERING PART C-METHODS
- GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes
- (2010) M. Daans et al. ANNALS OF THE RHEUMATIC DISEASES
- The genetic epidemiology of osteoarthritis
- (2010) Ana M Valdes et al. CURRENT OPINION IN RHEUMATOLOGY
- Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage
- (2010) Peter Dy et al. DEVELOPMENTAL BIOLOGY
- Directed differentiation of human embryonic stem cells toward chondrocytes
- (2010) Rachel A Oldershaw et al. NATURE BIOTECHNOLOGY
- Adipose-Derived Mesenchymal Stem Cells Treated with Growth Differentiation Factor-5 Express Tendon-Specific Markers
- (2010) Andrew Park et al. TISSUE ENGINEERING PART A
- Large-scale analysis of association betweenGDF5andFRZBvariants and osteoarthritis of the hip, knee, and hand
- (2009) Evangelos Evangelou et al. ARTHRITIS AND RHEUMATISM
- Functional analysis of the osteoarthritis susceptibility-associatedGDF5regulatory polymorphism
- (2009) Rainer J. Egli et al. ARTHRITIS AND RHEUMATISM
- Bone morphogenetic protein receptors and signal transduction
- (2009) K. Miyazono et al. JOURNAL OF BIOCHEMISTRY
- Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment
- (2009) B. Appel et al. OSTEOARTHRITIS AND CARTILAGE
- Growth Factors, Matrices, and Forces Combine and Control Stem Cells
- (2009) D. E. Discher et al. SCIENCE
- The Basic Science of Articular Cartilage: Structure, Composition, and Function
- (2009) Alice J. Sophia Fox et al. Sports Health-A Multidisciplinary Approach
- A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis
- (2008) Eiki Koyama et al. DEVELOPMENTAL BIOLOGY
- Trps1 plays a pivotal role downstream of Gdf5 signaling in promoting chondrogenesis and apoptosis of ATDC5 cells
- (2008) Shunji Itoh et al. GENES TO CELLS
- Adenovirus-mediated expression of growth and differentiation factor-5 promotes chondrogenesis of adipose stem cells
- (2008) Gang Feng et al. GROWTH FACTORS
- Effects induced by BMPS in cultures of human articular chondrocytes: Comparative studies
- (2008) Susan Chubinskaya et al. GROWTH FACTORS
- A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility
- (2008) K. Chapman et al. HUMAN MOLECULAR GENETICS
- Heterotypy in the N-Terminal Region of Growth/Differentiation Factor 5 (GDF5) Mature Protein during Teleost Evolution
- (2008) Koji Fujimura et al. MOLECULAR BIOLOGY AND EVOLUTION
- Modulatory effects of inflammation and therapy on GDF‐5 expression in rheumatoid arthritis synovium
- (2008) C. P. Bramlage et al. SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
- The growth differentiation factor 5 (GDF5) core promoter polymorphism is not associated with knee osteoarthritis in the greek population
- (2007) Aspasia Tsezou et al. JOURNAL OF ORTHOPAEDIC RESEARCH
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