Evolutionary Selection and Constraint on Human Knee Chondrocyte Regulation Impacts Osteoarthritis Risk

Published 2020 View Full Article

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Title
Evolutionary Selection and Constraint on Human Knee Chondrocyte Regulation Impacts Osteoarthritis Risk
Authors
Keywords
osteoarthritis, knee, gene regulation, ATAC-seq, human evolution, natural selection, genetic drift, GDF5, mouse model, chondrocyte
Journal
CELL
Volume 181, Issue 2, Pages 362-381.e28
Publisher
Elsevier BV
Online
2020-03-27
DOI
10.1016/j.cell.2020.02.057

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