Baicalein inhibits heparin-induced Tau aggregation by initializing non-toxic Tau oligomer formation

Re-epithelialization and immune cell behaviour in an ex vivo human skin model

(2020) Ana Rakita et al.   Scientific Reports

Role of cysteines in accelerating Tau filament formation

(2020) Hariharakrishnan Chidambaram et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Protein-Capped Metal Nanoparticles Inhibit Tau Aggregation in Alzheimer’s Disease

(2019) Shweta Kishor Sonawane et al.   ACS Omega

Molecular Cobalt(II) Complexes for Tau Polymerization in Alzheimer’s Disease

(2019) Nalini Vijay Gorantla et al.   ACS Omega

Baicalein suppresses Repeat Tau fibrillization by sequestering oligomers

(2019) Shweta Kishor Sonawane et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Brahmi (Bacopa monnieri): An ayurvedic herb against the Alzheimer's disease

(2019) Tushar Dubey et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Melatonin interacts with repeat domain of Tau to mediate disaggregation of paired helical filaments

(2019) Abhishek Ankur Balmik et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Spreading of Tau Pathology in Sporadic Alzheimer’s Disease Along Cortico-cortical Top-Down Connections

(2018) Heiko Braak et al.   CEREBRAL CORTEX

Natural Polyphenols in the Treatment of Alzheimer’s Disease

(2018) Syed-Badrul Syarifah-Noratiqah et al.   CURRENT DRUG TARGETS

Prion-Like Propagation of Post-Translationally Modified Tau in Alzheimer’s Disease: A Hypothesis

(2018) Shweta Kishor Sonawane et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Natural polyphenols effects on protein aggregates in Alzheimer's and Parkinson's prion-like diseases

(2018) AgnèsRioux Bilan et al.   Neural Regeneration Research

Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease

(2018) Fuyuki Kametani et al.   Frontiers in Neuroscience

Interaction of Cinnamaldehyde and Epicatechin with Tau: Implications of Beneficial Effects in Modulating Alzheimer's Disease Pathogenesis

(2018) Roshni C. George et al.   JOURNAL OF ALZHEIMERS DISEASE

Comprehensive review of antimicrobial activities of plant flavonoids

(2018) Ireneusz Górniak et al.   PHYTOCHEMISTRY REVIEWS

Biocompatible nanoemulsions based on hemp oil and less surfactants for oral delivery of baicalein with enhanced bioavailability

(2017) Juntao Yin et al.   International Journal of Nanomedicine

Curcumin Inhibits Tau Aggregation and Disintegrates Preformed Tau Filaments in vitro

(2017) Jitendra Subhash Rane et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer’s Disease: Past, Present, and Future

(2017) Mark W. Bondi et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Neuroprotective Effects of Baicalein on Acrolein-induced Neurotoxicity in the Nigrostriatal Dopaminergic System of Rat Brain

(2017) Wei-Zhong Zhao et al.   MOLECULAR NEUROBIOLOGY

A systemic view of Alzheimer disease — insights from amyloid-β metabolism beyond the brain

(2017) Jun Wang et al.   Nature Reviews Neurology

The Effects of Baicalin and Baicalein on Cerebral Ischemia: A Review

(2017) Wei Liang et al.   Aging and Disease

Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells

(2017) Xiaping He et al.   Frontiers in Neuroscience

Cinnamon Extract Inhibits Tau Aggregation Associated with Alzheimer's Disease In Vitro

(2017) Dylan W. Peterson et al.   JOURNAL OF ALZHEIMERS DISEASE

2016 Alzheimer's disease facts and figures

(2016)   Alzheimers & Dementia

The flavonoid baicalein rescues synaptic plasticity and memory deficits in a mouse model of Alzheimer’s disease

(2016) Xun-Hu Gu et al.   BEHAVIOURAL BRAIN RESEARCH

Neuroprotective Role of Natural Polyphenols

(2016) Carmela Spagnuolo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Baicalein attenuates α-synuclein aggregation, inflammasome activation and autophagy in the MPP+-treated nigrostriatal dopaminergic system in vivo

(2016) Kai-Chih Hung et al.   JOURNAL OF ETHNOPHARMACOLOGY

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Tau Structures

(2016) Jesus Avila et al.   Frontiers in Aging Neuroscience

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

Baicalein prevents human prion protein-induced neuronal cell death by regulating JNK activation

(2014) JI-HONG MOON et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction

(2014) Anna Mietelska-Porowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stages and Conformations of the Tau Repeat Domain during Aggregation and Its Effect on Neuronal Toxicity

(2014) Satish Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Baicalin, a metabolite of baicalein with antiviral activity against dengue virus

(2014) Ehsan Moghaddam et al.   Scientific Reports

Mechanistic Basis of Phenothiazine-Driven Inhibition of Tau Aggregation

(2013) Elias Akoury et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interaction between baicalein and amyloid-β fibrils studied by fluorescence spectroscopy

(2013) Sheng-mei Song et al.   CHEMICAL RESEARCH IN CHINESE UNIVERSITIES

Aminothienopyridazines and Methylene Blue Affect Tau Fibrillization via Cysteine Oxidation

(2013) Alex Crowe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-  species

(2013) S.-J. Hyung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural polyphenols against neurodegenerative disorders: Potentials and pitfalls

(2012) Azadeh Ebrahimi et al.   AGEING RESEARCH REVIEWS

The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System

(2012) Hwan-Ching Tai et al.   AMERICAN JOURNAL OF PATHOLOGY

Structural Properties of EGCG-Induced, Nontoxic Alzheimer's Disease Aβ Oligomers

(2012) Juan Miguel Lopez del Amo et al.   JOURNAL OF MOLECULAR BIOLOGY

Synapses and Alzheimer's Disease

(2012) M. Sheng et al.   Cold Spring Harbor Perspectives in Biology

Baicalein Inhibits Formation of α-Synuclein Oligomers within Living Cells and Prevents Aβ Peptide Fibrillation and Oligomerisation

(2011) Jia-Hong Lu et al.   CHEMBIOCHEM

Post-translational modifications of tau protein: Implications for Alzheimer's disease

(2011) Ludovic Martin et al.   NEUROCHEMISTRY INTERNATIONAL

Baicalein inhibits oxidative stress-induced cellular damage via antioxidant effects

(2011) Kyoung Ah Kang et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Oxidative stress and Alzheimer’s disease: dietary polyphenols as potential therapeutic agents

(2010) Altaf S Darvesh et al.   Expert Review of Neurotherapeutics

Binding Modes of Flavones to Human Serum Albumin: Insights from Experimental and Computational Studies

(2010) Hui Liu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau

(2009) Wenkai Li et al.   JOURNAL OF NEUROCHEMISTRY

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

(2009) Diane P. Hanger et al.   TRENDS IN MOLECULAR MEDICINE

Structural Characteristics of α-Synuclein Oligomers Stabilized by the Flavonoid Baicalein

(2008) Dong-Pyo Hong et al.   JOURNAL OF MOLECULAR BIOLOGY