RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization

Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features

(2019) Rémi Buisson et al.   SCIENCE

Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancer

(2019) A. J. Robert McGray et al.   Journal for ImmunoTherapy of Cancer

CRISPR DNA base editors with reduced RNA off-target and self-editing activities

(2019) Julian Grünewald et al.   NATURE BIOTECHNOLOGY

Tumor associated macrophages in gynecologic cancers

(2018) Venkatesh Krishnan et al.   GYNECOLOGIC ONCOLOGY

Oncolytic Virus Combination Therapy: Killing One Bird with Two Stones

(2018) Nikolas Tim Martin et al.   MOLECULAR THERAPY

A-to-I RNA editing — immune protector and transcriptome diversifier

(2018) Eli Eisenberg et al.   NATURE REVIEWS GENETICS

Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes

(2017) Shraddha Sharma et al.   HUMAN MOLECULAR GENETICS

Promising landscape for regulating macrophage polarization: epigenetic viewpoint

(2017) Dexi Zhou et al.   Oncotarget

Stem-loop structure preference for site-specific RNA editing by APOBEC3A and APOBEC3G

(2017) Shraddha Sharma et al.   PeerJ

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

(2016) Evanna L. Mills et al.   CELL

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

(2016) Shih-Chin Cheng et al.   NATURE IMMUNOLOGY

Transient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes

(2016) Shraddha Sharma et al.   RNA Biology

The APOBEC Protein Family: United by Structure, Divergent in Function

(2016) Jason D. Salter et al.   TRENDS IN BIOCHEMICAL SCIENCES

The double-domain cytidine deaminase APOBEC3G is a cellular site-specific RNA editing enzyme

(2016) Shraddha Sharma et al.   Scientific Reports

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

(2015) Tamás Rőszer   MEDIATORS OF INFLAMMATION

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

(2015) Kin Chan et al.   NATURE GENETICS

UPR, autophagy, and mitochondria crosstalk underlies the ER stress response

(2015) Daniela Senft et al.   TRENDS IN BIOCHEMICAL SCIENCES

APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages

(2015) Shraddha Sharma et al.   Nature Communications

Macrophage polarization in response to ECM coated polypropylene mesh

(2014) Matthew T. Wolf et al.   BIOMATERIALS

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Endogenous APOBEC3A DNA Cytosine Deaminase Is Cytoplasmic and Nongenotoxic

(2013) Allison M. Land et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maraba Virus as a Potent Oncolytic Vaccine Vector

(2013) Jonathan G Pol et al.   MOLECULAR THERAPY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Transcriptional regulation of immediate-early gene response by THOC5, a member of mRNA export complex, contributes to the M-CSF-induced macrophage differentiation

(2013) D DH Tran et al.   Cell Death & Disease

Hypoxia-inducible C-to-U coding RNA editing downregulatesSDHBin monocytes

(2013) Bora E. Baysal et al.   PeerJ

Regulation ofAicdaexpression and AID activity

(2012) Hong Zan et al.   AUTOIMMUNITY

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

Identification of Genetically Modified Maraba Virus as an Oncolytic Rhabdovirus

(2010) Jan Brun et al.   MOLECULAR THERAPY

Molecular diversity through RNA editing: a balancing act

(2010) Sanaz Farajollahi et al.   TRENDS IN GENETICS

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The current structural and functional understanding of APOBEC deaminases

(2009) Ronda Bransteitter et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Macrophages and Inflammatory Mediators in Chemical Toxicity: A Battle of Forces

(2009) Debra L. Laskin   CHEMICAL RESEARCH IN TOXICOLOGY

Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA

(2009) Jun Katahira et al.   EMBO JOURNAL

THOC5 couples M-CSF receptor signaling to transcription factor expression

(2008) Louise Carney et al.   CELLULAR SIGNALLING

The AID/APOBEC family of nucleic acid mutators

(2008) Silvestro G Conticello   GENOME BIOLOGY

Macrophage activation by endogenous danger signals

(2007) X Zhang et al.   JOURNAL OF PATHOLOGY