The Leukotriene Receptor Antagonist Montelukast as a Potential COVID-19 Therapeutic
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Title
The Leukotriene Receptor Antagonist Montelukast as a Potential COVID-19 Therapeutic
Authors
Keywords
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Journal
Frontiers in Molecular Biosciences
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-01-08
DOI
10.3389/fmolb.2020.610132
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Note: Only part of the references are listed.- Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2
- (2020) Xi Xu et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Stepping up infection control measures in ophthalmology during the novel coronavirus outbreak: an experience from Hong Kong
- (2020) Tracy H. T. Lai et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China
- (2020) Zunyou Wu et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China
- (2020) Dawei Wang et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The neuroinvasive potential of SARS‐CoV2 may be at least partially responsible for the respiratory failure of COVID‐19 patients
- (2020) Yan‐Chao Li et al. JOURNAL OF MEDICAL VIROLOGY
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study
- (2020) Heshui Shi et al. LANCET INFECTIOUS DISEASES
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies
- (2020) Julia Marschallinger et al. Neurotherapeutics
- Clinical Characteristics of Coronavirus Disease 2019 in China
- (2020) Wei-jie Guan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
- (2020) Qun Li et al. NEW ENGLAND JOURNAL OF MEDICINE
- Montelukast, an Anti-asthmatic Drug, Inhibits Zika Virus Infection by Disrupting Viral Integrity
- (2020) Yongkang Chen et al. Frontiers in Microbiology
- Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
- (2020) Canrong Wu et al. Acta Pharmaceutica Sinica B
- Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host–Virus Interaction, and Proposed Neurotropic Mechanisms
- (2020) Abdul Mannan Baig et al. ACS Chemical Neuroscience
- SARS-CoV-2 can induce brain and spine demyelinating lesions
- (2020) Luca Zanin et al. ACTA NEUROCHIRURGICA
- Hematological findings and complications of COVID ‐19
- (2020) Evangelos Terpos et al. AMERICAN JOURNAL OF HEMATOLOGY
- Mechanism of thrombocytopenia in COVID-19 patients
- (2020) Panyang Xu et al. ANNALS OF HEMATOLOGY
- COVID ‐19, pulmonary mast cells, cytokine storms, and beneficial actions of luteolin
- (2020) Theoharis C. Theoharides BIOFACTORS
- The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system
- (2020) Francesca Coperchini et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Clinical Presentation of COVID-19: A Systematic Review Focusing on Upper Airway Symptoms
- (2020) Andrea Lovato et al. ENT-EAR NOSE & THROAT JOURNAL
- Does SARS‐Cov‐2 invade the brain? Translational lessons from animal models
- (2020) S. Natoli et al. EUROPEAN JOURNAL OF NEUROLOGY
- COVID-19 update: Covid-19-associated coagulopathy
- (2020) Richard C. Becker JOURNAL OF THROMBOSIS AND THROMBOLYSIS
- Retinal findings in patients with COVID-19
- (2020) Paula M Marinho et al. LANCET
- COVID-19: consider cytokine storm syndromes and immunosuppression
- (2020) Puja Mehta et al. LANCET
- Association between platelet parameters and mortality in coronavirus disease 2019: Retrospective cohort study
- (2020) Yanli Liu et al. PLATELETS
- COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features
- (2020) Neo Poyiadji et al. RADIOLOGY
- Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
- (2020) Linlin Zhang et al. SCIENCE
- Sars-Cov-2: Underestimated damage to nervous system
- (2020) Lingyan Zhou et al. Travel Medicine and Infectious Disease
- Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China
- (2020) Ling Mao et al. JAMA Neurology
- Characteristics of Ocular Findings of Patients With Coronavirus Disease 2019 (COVID-19) in Hubei Province, China
- (2020) Ping Wu et al. JAMA Ophthalmology
- Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)
- (2020) Bo Diao et al. Frontiers in Immunology
- Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 — COVID-NET, 14 States, March 1–30, 2020
- (2020) Shikha Garg et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science
- (2020) Paul C Evans et al. CARDIOVASCULAR RESEARCH
- Neurological manifestations of COVID-19 and other coronavirus infections: A systematic review
- (2020) V. Montalvan et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- Potential Novel Role of COVID-19 in Alzheimer’s Disease and Preventative Mitigation Strategies
- (2020) Sean X. Naughton et al. JOURNAL OF ALZHEIMERS DISEASE
- Clinical manifestations and evidence of neurological involvement in 2019 novel coronavirus SARS-CoV-2: a systematic review and meta-analysis
- (2020) Lei Wang et al. JOURNAL OF NEUROLOGY
- Central nervous system manifestations of COVID-19: A systematic review
- (2020) Ali A. Asadi-Pooya et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface
- (2020) Joseph Collin et al. Ocular Surface
- Thrombosis risk associated with COVID-19 infection. A scoping review
- (2020) Fatimah Al-Ani et al. THROMBOSIS RESEARCH
- As a potential treatment of COVID-19: Montelukast
- (2020) Cihan Fidan et al. MEDICAL HYPOTHESES
- The association between obesity and poor outcome after COVID-19 indicates a potential therapeutic role for montelukast
- (2020) Muhammad Qutayba Almerie et al. MEDICAL HYPOTHESES
- Mechanisms involved in the development of thrombocytopenia in patients with COVID-19
- (2020) Yujiao Zhang et al. THROMBOSIS RESEARCH
- The synergistic effects of clopidogrel with montelukast may be beneficial for asthma treatment
- (2019) Hoang Kim Tu Trinh et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Leukotriene B 4 receptors mediate the production of IL ‐17, thus contributing to neutrophil‐dominant asthmatic airway inflammation
- (2019) MyungJa Ro et al. ALLERGY
- Effect of montelukast combined with methylprednisolone for the treatment of mycoplasma pneumonia
- (2019) Hongtu Wu et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Improvement of fiber connectivity and functional recovery after stroke by montelukast, an available and safe anti-asthmatic drug
- (2019) Paolo Gelosa et al. PHARMACOLOGICAL RESEARCH
- Montelukast, Leukotriene Inhibitor, Reduces LPS-Induced Acute Lung Inflammation and Human Neutrophil Activation
- (2019) Jaime Eduardo Davino-Chiovatto et al. ARCHIVOS DE BRONCONEUMOLOGIA
- Montelukast Prevents Early Diabetic Retinopathy in Mice
- (2019) Reena Bapputty et al. DIABETES
- Platelets: The missing link between the blood and brain?
- (2019) Odette Leiter et al. PROGRESS IN NEUROBIOLOGY
- Leukotriene receptors as potential therapeutic targets
- (2018) Takehiko Yokomizo et al. JOURNAL OF CLINICAL INVESTIGATION
- Effects of montelukast on M2-related cytokine and chemokine in M2 macrophages
- (2018) Yi-Ching Lin et al. JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
- Cangrelor alleviates pulmonary fibrosis by inhibiting GPR17-mediated inflammation in mice
- (2018) Tian-Wei Zhan et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Neurologic Alterations Due to Respiratory Virus Infections
- (2018) Karen Bohmwald et al. Frontiers in Cellular Neuroscience
- Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology
- (2017) Rudragouda Channappanavar et al. Seminars in Immunopathology
- Alveolar Macrophages Prevent Lethal Influenza Pneumonia By Inhibiting Infection Of Type-1 Alveolar Epithelial Cells
- (2017) Amber Cardani et al. PLoS Pathogens
- Effect of montelukast on markers of airway remodeling in children with asthma
- (2016) Laura Tenero et al. ALLERGY AND ASTHMA PROCEEDINGS
- Leukotriene E4elicits respiratory epithelial cell mucin release through the G-protein–coupled receptor, GPR99
- (2016) Lora G. Bankova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies
- (2016) Miles D. Thompson et al. Frontiers in Pharmacology
- Airway Platelet Activation Is Associated With Airway Eosinophilic Inflammation in Asthma
- (2016) Angela S. Benton et al. JOURNAL OF INVESTIGATIVE MEDICINE
- Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine- Directed Therapies
- (2015) Grant S. Schulert et al. Annual Review of Medicine
- P2Y12 antagonist attenuates eosinophilic inflammation and airway hyperresponsiveness in a mouse model of asthma
- (2015) Dong-Hyeon Suh et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Platelet-Driven Leukotriene C4–Mediated Airway Inflammation in Mice Is Aspirin-Sensitive and Depends on T Prostanoid Receptors
- (2015) Tao Liu et al. JOURNAL OF IMMUNOLOGY
- Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug
- (2015) Julia Marschallinger et al. Nature Communications
- Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7
- (2014) Magnus Bäck et al. BRITISH JOURNAL OF PHARMACOLOGY
- Montelukast reduces sepsis-induced lung and renal injury in rats
- (2014) Ahmed E. Khodir et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Coronaviruses: Important Emerging Human Pathogens
- (2014) C. M. Coleman et al. JOURNAL OF VIROLOGY
- Cysteinyl leukotriene receptor (CysLT) antagonists decrease pentylenetetrazol-induced seizures and blood–brain barrier dysfunction
- (2014) Q.F. Lenz et al. NEUROSCIENCE
- Antileukotriene Agents for the Treatment of Lung Disease
- (2013) Jacob P. Scott et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Targeting CCL5 in inflammation
- (2013) Rafael Elias Marques et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Cutting Edge: Leukotriene C4 Activates Mouse Platelets in Plasma Exclusively through the Type 2 Cysteinyl Leukotriene Receptor
- (2013) H. E. Cummings et al. JOURNAL OF IMMUNOLOGY
- Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group
- (2013) R. J. de Groot et al. JOURNAL OF VIROLOGY
- Characterisation of P2Y12 Receptor Responsiveness to Cysteinyl Leukotrienes
- (2013) Holly R. Foster et al. PLoS One
- Inhibitory effects of Montelukast on mediator release by nasal epithelial cells from asthmatic subjects with or without allergic rhinitis
- (2013) A. Scaife et al. RESPIRATORY MEDICINE
- Cysteinyl leukotriene receptor antagonist montelukast ameliorates acute lung injury following haemorrhagic shock in rats†
- (2012) Fadhil G. Al-Amran et al. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
- Nationwide cohort study of the leukotriene receptor antagonist montelukast and incident or recurrent cardiovascular disease
- (2012) Erik Ingelsson et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Leukotrienes and airway inflammation
- (2011) Katsuhide Okunishi et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Antiasthmatic Drugs Targeting the Cysteinyl Leukotriene Receptor 1 Alleviate Central Nervous System Inflammatory Cell Infiltration and Pathogenesis of Experimental Autoimmune Encephalomyelitis
- (2011) L. Wang et al. JOURNAL OF IMMUNOLOGY
- Montelukast during Primary Infection Prevents Airway Hyperresponsiveness and Inflammation after Reinfection with Respiratory Syncytial Virus
- (2010) Junyan Han et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Effect of Citrus Juice andSLCO2B1Genotype on the Pharmacokinetics of Montelukast
- (2010) E. B. Mougey et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Functional expression of cysteinyl leukotriene receptors on human platelets
- (2010) Shunji Hasegawa et al. PLATELETS
- Montelukast in asthma: a review of its efficacy and place in therapy
- (2010) Pierluigi Paggiaro et al. Therapeutic Advances in Chronic Disease
- Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-dependent mechanism
- (2009) Ronald Anderson et al. BRITISH JOURNAL OF PHARMACOLOGY
- Montelukast in the treatment of asthma and beyond
- (2009) Zuzana Diamant et al. Expert Review of Clinical Immunology
- Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response
- (2009) Edward B. Mougey et al. Pharmacogenetics and Genomics
- Montelukast inhibits tumour necrosis factor-α-mediated interleukin-8 expression through inhibition of nuclear factor-κB p65-associated histone acetyltransferase activity
- (2008) F. Tahan et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Expanding roles for leukotrienes in airway inflammation
- (2008) Marc Peters-Golden CURRENT ALLERGY AND ASTHMA REPORTS
- Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2
- (2008) J. Netland et al. JOURNAL OF VIROLOGY
- Dynamic Dissolution Testing To Establish In Vitro/In Vivo Correlations for Montelukast Sodium, a Poorly Soluble Drug
- (2008) Arthur Okumu et al. PHARMACEUTICAL RESEARCH
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