Targeting CCL5 in inflammation

Interaction between RANTES Promoter Variant and CCR5 32 Favors Recovery from Hepatitis B

(2014) C. L. Thio et al.   JOURNAL OF IMMUNOLOGY

Peptide Inhibitor of CXCL4–CCL5 Heterodimer Formation, MKEY, Inhibits Experimental Aortic Aneurysm Initiation and Progression

(2013) Yasunori Iida et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Absence of CCR5 increases neutrophil recruitment in severe herpetic encephalitis

(2013) Márcia Carvalho Vilela et al.   BMC NEUROSCIENCE

Seasonal and pandemic influenza H1N1 viruses induce differential expression of SOCS-1 and RIG-I genes and cytokine/chemokine production in macrophages

(2013) Gustavo Ramírez-Martínez et al.   CYTOKINE

IL-22 modulates IL-17A production and controls inflammation and tissue damage in experimental dengue infection

(2013) Rodrigo Guabiraba et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Resolution of inflammation: Mechanisms and opportunity for drug development

(2013) Ana L. Alessandri et al.   PHARMACOLOGY & THERAPEUTICS

Asthma Phenotypes in Japanese Adults - Their Associations with the CCL5 ADRB2 Genotypes

(2013) Yoshiko Kaneko et al.   ALLERGOLOGY INTERNATIONAL

RANTES/CCL5-induced pro-angiogenic effects depend on CCR1, CCR5 and glycosaminoglycans

(2012) N. Suffee et al.   ANGIOGENESIS

CCR1 blockade reduces tumor burden and osteolysis in vivo in a mouse model of myeloma bone disease

(2012) D. J. Dairaghi et al.   BLOOD

The role of chemokines in the pathogenesis of neurotropic flaviviruses

(2012) Susana V. Bardina et al.   IMMUNOLOGIC RESEARCH

Subversion of cytokine networks by virally encoded decoy receptors

(2012) Megan L. Epperson et al.   IMMUNOLOGICAL REVIEWS

T cell homing to epithelial barriers in allergic disease

(2012) Sabina A Islam et al.   NATURE MEDICINE

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Innate Immune Response of Human Alveolar Macrophages during Influenza A Infection

(2012) Jieru Wang et al.   PLoS One

Regulation of Inflammatory Chemokine Receptors on Blood T Cells Associated to the Circulating Versus Liver Chemokines in Dengue Fever

(2012) Luzia Maria de-Oliveira-Pinto et al.   PLoS One

Human Cytomegalovirus Clinical Strain-Specific microRNA miR-UL148D Targets the Human Chemokine RANTES during Infection

(2012) Youngkyun Kim et al.   PLoS Pathogens

Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis

(2011) Zhiyong Mi et al.   CARCINOGENESIS

Pharmacokinetic and Pharmacodynamic Evaluation of the Novel CCR1 Antagonist CCX354 in Healthy Human Subjects: Implications for Selection of Clinical Dose

(2011) D J Dairaghi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Experimental Infection withSchistosoma mansoniin CCR5-Deficient Mice Is Associated with Increased Disease Severity, as CCR5 Plays a Role in Controlling Granulomatous Inflammation

(2011) Adriano L. S. Souza et al.   INFECTION AND IMMUNITY

Significantly increased CCL5/RANTES and CCR7 mRNA levels in localized scleroderma

(2011) Thilo Gambichler et al.   REGULATORY PEPTIDES

Astrocytes modulate the chemokine network in a pathogen-specific manner

(2010) Clive S. McKimmie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice

(2010) Marie-Luise Berres et al.   JOURNAL OF CLINICAL INVESTIGATION

Rabies Virus Nucleoprotein Functions To Evade Activation of the RIG-I-Mediated Antiviral Response

(2010) T. Masatani et al.   JOURNAL OF VIROLOGY

Tolerability and efficacy of inhaled AZD4818, a CCR1 antagonist, in moderate to severe COPD patients

(2010) Huib A. Kerstjens et al.   RESPIRATORY MEDICINE

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

(2009) H. Harlin et al.   CANCER RESEARCH

Chemokine receptor oligomerization: functional considerations

(2009) Marcus Thelen et al.   CURRENT OPINION IN PHARMACOLOGY

The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6

(2009) S. Vetrano et al.   GUT

CCL5 secreted by senescent aged fibroblasts induces proliferation of prostate epithelial cells and expression of genes that modulate angiogenesis

(2009) D. Eyman et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Unexpected Pleiotropic Activities of RANTES

(2009) J. A. Levy   JOURNAL OF IMMUNOLOGY

Hantaan Virus Triggers TLR3-Dependent Innate Immune Responses

(2009) W. Handke et al.   JOURNAL OF IMMUNOLOGY

Gamma Interferon Signaling in Macrophage Lineage Cells Regulates Central Nervous System Inflammation and Chemokine Production

(2009) A. A. Lin et al.   JOURNAL OF VIROLOGY

The Roles of Chemokines in Rabies Virus Infection: Overexpression May Not Always Be Beneficial

(2009) L. Zhao et al.   JOURNAL OF VIROLOGY

Role of the chemokines CCL3/MIP-1α and CCL5/RANTES in sponge-induced inflammatory angiogenesis in mice

(2009) Lucíola S. Barcelos et al.   MICROVASCULAR RESEARCH

Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

(2009) Rory R Koenen et al.   NATURE MEDICINE

Pathology, Molecular Biology, and Pathogenesis of Avian Influenza A (H5N1) Infection in Humans

(2008) Christine Korteweg et al.   AMERICAN JOURNAL OF PATHOLOGY

A Novel RANTES Antagonist Prevents Progression of Established Atherosclerotic Lesions in Mice

(2008) Vincent Braunersreuther et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Chemokines in Atherosclerosis

(2008) Alma Zernecke et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Housekeeping by chemokine scavenging

(2008) A. Mantovani et al.   BLOOD

Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues

(2008) A. E. Cardona et al.   BLOOD

The role of chemokines during herpes simplex virus-1 infection

(2008) Todd et al.   Frontiers in Bioscience-Landmark

CXC and CC Chemokines Form Mixed Heterodimers

(2008) Irina V. Nesmelova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ccr1 deficiency reduces inflammatory remodelling and preserves left ventricular function after myocardial infarction

(2008) E. A. Liehn et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Case of Yellow Fever Vaccine–Associated Viscerotropic Disease with Prolonged Viremia, Robust Adaptive Immune Responses, and Polymorphisms in CCR5 and RANTES Genes

(2008) Bali Pulendran et al.   JOURNAL OF INFECTIOUS DISEASES

A Deletion in the Chemokine Receptor 5(CCR5)Gene Is Associated with Tickborne Encephalitis

(2008) Elin Kindberg et al.   JOURNAL OF INFECTIOUS DISEASES

Astrocytes play a key role in activation of microglia by persistent Borna disease virus infection

(2008) Mikhail V Ovanesov et al.   Journal of Neuroinflammation

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

How chemokines invite leukocytes to dance

(2008) Marcus Thelen et al.   NATURE IMMUNOLOGY

Treatment of yellow fever

(2007) Thomas P. Monath   ANTIVIRAL RESEARCH