COVID ‐19, pulmonary mast cells, cytokine storms, and beneficial actions of luteolin

Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury

(2020) Clark D Russell et al.   LANCET

Emergence of a novel human coronavirus threatening human health

(2020) Leo L. M. Poon et al.   NATURE MEDICINE

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine

(2020) Wanbo Tai et al.   Cellular & Molecular Immunology

Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19

(2020) Irani Thevarajan et al.   NATURE MEDICINE

A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19

(2020) Andrea Cortegiani et al.   JOURNAL OF CRITICAL CARE

Luteolin decreases the yield of influenza A virus in vitro by interfering with the coat protein I complex expression

(2019) Haiyan Yan et al.   Journal of Natural Medicines

Mast Cell Responses to Viruses and Pathogen Products

(2019) Jean S. Marshall et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of SARS-CoV 3CL protease by flavonoids

(2019) Seri Jo et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IL-33 stimulates human mast cell release of CCL5 and CCL2 via MAPK and NF-κB, inhibited by methoxyluteolin

(2019) Mona Abubakr Bawazeer et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mast cells as sources of cytokines, chemokines, and growth factors

(2018) Kaori Mukai et al.   IMMUNOLOGICAL REVIEWS

Mast cells signal their importance in health and disease

(2018) Ana Olivera et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Substance P and IL-33 administered together stimulate a marked secretion of IL-1β from human mast cells, inhibited by methoxyluteolin

(2018) Alexandra Taracanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methoxyluteolin Inhibits Neuropeptide-stimulated Proinflammatory Mediator Release via mTOR Activation from Human Mast Cells

(2017) Arti B. Patel et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Metabolic interactions between acetaminophen (paracetamol) and two flavonoids, luteolin and quercetin, through in-vitro inhibition studies

(2017) Lei Cao et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors

(2017) Alexandra Taracanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A structural mechanism of flavonoids in inhibiting serine proteases

(2017) Guangpu Xue et al.   Food & Function

Antiviral activity of luteolin against Japanese encephalitis virus

(2016) Wenchun Fan et al.   VIRUS RESEARCH

The novel flavone tetramethoxyluteolin is a potent inhibitor of human mast cells

(2015) Zuyi Weng et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mast Cells, Mastocytosis, and Related Disorders

(2015) Theoharis C. Theoharides et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of Luteolin as Enterovirus 71 and Coxsackievirus A16 Inhibitors through Reporter Viruses and Cell Viability-Based Screening

(2014) Lin Xu et al.   Viruses-Basel

Developmental Origin and Functional Specialization of Mast Cell Subsets

(2012) Michael F. Gurish et al.   IMMUNITY

Mast cells and inflammation

(2010) Theoharis C. Theoharides et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Anti-Oxidant, Anti-Inflammatory and Anti-Allergic Activities of Luteolin

(2008) Günter Seelinger et al.   PLANTA MEDICA

Mast cell renin and a local renin-angiotensin system in the airway: Role in bronchoconstriction

(2008) A. Veerappan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA