Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies

Cellular signalling of cysteinyl leukotriene type 1 receptor variants CysLT1-G300S and CysLT1-I206S

(2016) Louiza Yaddaden et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Genome-wide association study of leukotriene modifier response in asthma

(2015) A Dahlin et al.   PHARMACOGENOMICS JOURNAL

Prevalence and severity of asthmatic symptoms in Grenadian school children: the Grenada National Asthma Survey

(2015) D Thongkham et al.   BMJ Open

Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma

(2015) Amber Dahlin et al.   PLoS One

OX1 and OX2 orexin/hypocretin receptor pharmacogenetics

(2014) Miles D. Thompson et al.   Frontiers in Neuroscience

LTC4 synthase polymorphism modifies efficacy of botanical seed oil combination in asthma

(2014) Shamsah Kazani et al.   SpringerPlus

Identification of GPR99 Protein as a Potential Third Cysteinyl Leukotriene Receptor with a Preference for Leukotriene E4Ligand

(2013) Yoshihide Kanaoka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estimating heritability in pharmacogenetic studies

(2013) Scott L Marshall et al.   PHARMACOGENOMICS

Interaction between Retinoid Acid Receptor-Related Orphan Receptor Alpha (RORA) and Neuropeptide S Receptor 1 (NPSR1) in Asthma

(2013) Nathalie Acevedo et al.   PLoS One

Does homologous reinfection drive multiple-wave influenza outbreaks? Accounting for immunodynamics in epidemiological models

(2013) A. Camacho et al.   Epidemics

The −444A/C Polymorphism in the LTC4S Gene and the Risk of Asthma: A Meta-analysis

(2012) Yonggang Zhang et al.   ARCHIVES OF MEDICAL RESEARCH

ALOX5Polymorphism associates with increased leukotriene production and reduced lung function and asthma control in children with poorly controlled asthma

(2012) E. Mougey et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Genome-wide association study of body mass index in 23 000 individuals with and without asthma

(2012) E. Melén et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Association of the –1072G/A Polymorphism in the LTC4S Gene with Asthma in an Indian Population

(2012) Amrendra Kumar et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma

(2012) V Berce et al.   PHARMACOGENOMICS JOURNAL

Polymorphisms of the PTGDR and LTC4S influence responsiveness to leukotriene receptor antagonists in Korean children with asthma

(2011) Mi-Jin Kang et al.   JOURNAL OF HUMAN GENETICS

Chromosome 1p36 in migraine with aura

(2011) Miles D. Thompson et al.   NEUROREPORT

Explaining rapid reinfections in multiple-wave influenza outbreaks: Tristan da Cunha 1971 epidemic as a case study

(2011) A. Camacho et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The asthma candidate gene NPSR1 mediates isoform specific downstream signalling

(2011) Christina Orsmark Pietras et al.   BMC Pulmonary Medicine

Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia

(2010) Manuel A R Ferreira et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Effect of Citrus Juice andSLCO2B1Genotype on the Pharmacokinetics of Montelukast

(2010) E. B. Mougey et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Cysteinyl leukotriene receptor 2 gene polymorphism -1220 A/C is not associated with atopic dermatitis or psoriasis vulgaris in Japanese patients

(2010) Toyoaki KATO et al.   JOURNAL OF DERMATOLOGY

Differential Signaling Defects Associated with the M201V Polymorphism in the Cysteinyl Leukotriene Type 2 Receptor

(2010) A. Brochu-Bourque et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

GPCRDB: information system for G protein-coupled receptors

(2010) B. Vroling et al.   NUCLEIC ACIDS RESEARCH

Unifying Candidate Gene and GWAS Approaches in Asthma

(2010) Sven Michel et al.   PLoS One

Variable expression of cysteinyl leukotriene type I receptor splice variants in asthmatic females with different promoter haplotypes

(2009) Milena Sokolowska et al.   BMC IMMUNOLOGY

In silico mutagenesis: a case study of the melanocortin 4 receptor

(2009) Yana Bromberg et al.   FASEB JOURNAL

Association of the cysteinyl leukotriene receptor 1 gene with atopy in the British 1958 birth cohort

(2009) Nathalie P. Duroudier et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Adrenergic β2-receptor genotype predisposes to exacerbations in steroid-treated asthmatic patients taking frequent albuterol or salmeterol

(2009) Kaninika Basu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genetics and pharmacogenetics of the leukotriene pathway

(2009) Kelan G. Tantisira et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A genome-wide association study on African-ancestry populations for asthma

(2009) Rasika A. Mathias et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Variants ofDENND1BAssociated with Asthma in Children

(2009) Patrick M.A. Sleiman et al.   NEW ENGLAND JOURNAL OF MEDICINE

5-Lipoxygenase pharmacogenetics in asthma: overlap with Cys-leukotriene receptor antagonist loci

(2009) Kelan G. Tantisira et al.   Pharmacogenetics and Genomics

Influence of leukotriene gene polymorphisms on chronic rhinosinusitis

(2008) Hasan Al-Shemari et al.   BMC Medical Genetics

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation

(2008) Jing Wu et al.   CELL RESEARCH

Cysteinyl leukotriene receptor 1 gene variation and risk of asthma

(2008) X. Hong et al.   EUROPEAN RESPIRATORY JOURNAL

Genetic variations in chemoattractant receptor expressed on Th2 cells (CRTH2) is associated with asthma susceptibility in Chinese children

(2008) Jinhui Wang et al.   MOLECULAR BIOLOGY REPORTS

Clinical consequences of ADRβ2 polymorphisms

(2008) Gregory A Hawkins et al.   PHARMACOGENOMICS

ALOX5 promoter genotype and response to montelukast in moderate persistent asthma

(2008) Juan J. Telleria et al.   RESPIRATORY MEDICINE